Jing Jin

  • 3888 Citations
19982023
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Personal profile

Research Interests

The lab is generally interested in the pathological mechanisms of kidney and vascular diseases. We take a proteomic approach to study molecules that serve structural or functional roles in kidney filtration. Particularly, we are trying to understand how the kidney podocytes maintain and regulate their slit diaphragm, as well as their interactions with the glomerular basement membrane.

Education/Academic qualification

PhD, University of Toronto

… → 2003

MD, Peking University

… → 1992

Research interests

  • Angiogenesis
  • Biochemistry: Proteins
  • Cardiovascular Diseases
  • Hypertension
  • Nephrology
  • Proteomics
  • Vascular Biology

Fingerprint Dive into the research topics where Jing Jin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Proto-Oncogene Proteins c-akt Medicine & Life Sciences
Phosphatidylinositol 3-Kinase Medicine & Life Sciences
Protein Kinases Medicine & Life Sciences
Proteins Medicine & Life Sciences
Phosphorylation Chemical Compounds
Carcinogenesis Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Angiopoietins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2014 2023

Focal Segmental Glomerulosclerosis
Organoids
Kidney
Proteome
Proteomics
Kidney
Kidney Diseases
Research Personnel
Therapeutics
Nanomedicine
Autoantibodies
Arginine
Antigens
Protein Array Analysis
Immune Tolerance
Angiopoietins
Ocular Hypertension
Glaucoma
Intraocular Pressure
Drainage
Insulin
Islets of Langerhans
Immune System
Antibodies
Poisons

Research Output 1998 2018

  • 3888 Citations
  • 31 Article
  • 3 Review article
  • 1 Comment/debate
10 Citations (Scopus)

Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP

Souma, T., Thomson, B. R., Heinen, S., Carota, I. A., Yamaguchi, S., Onay, T., Liu, P., Ghosh, A. K., Li, C., Eremina, V., Hong, Y. K., Economides, A. N., Vestweber, D., Peters, K. G., Jin, J. & Quaggina, S. E., Feb 6 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 6, p. 1298-1303 6 p.

Research output: Contribution to journalArticle

Class 3 Receptor-Like Protein Tyrosine Phosphatases
Angiopoietin-2
Phosphoric Monoester Hydrolases
Lymphatic Endothelium
Blood Vessels
4 Citations (Scopus)
Renin-Angiotensin System
Angiotensin II
Hypertension
Blood Pressure
Transgenic Mice
1 Citation (Scopus)

Selective permeability of mouse blood-aqueous barrier as determined by15N-heavy isotope tracing and mass spectrometry

Liu, P., Thomson, B. R., Khalatyan, N., Feng, L., Liu, X., Savas, J. N., Quaggin, S. E. & Jin, J., Sep 4 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 36, p. 9032-9037 6 p.

Research output: Contribution to journalArticle

Blood-Aqueous Barrier
Isotopes
Permeability
Mass Spectrometry
Blood Proteins
1 Citation (Scopus)

Transcription factor 21 is required for branching morphogenesis and regulates the Gdnf-Axis in kidney development

Ide, S., Finer, G., Maezawa, Y., Onay, T., Souma, T., Scott, R. P., Ide, K., Akimoto, Y., Li, C., Ye, M., Zhao, X., Baba, Y., Minamizuka, T., Jin, J., Takemoto, M., Yokote, K. & Quaggin, S. E., Dec 1 2018, In : Journal of the American Society of Nephrology. 29, 12, p. 2795-2808 14 p.

Research output: Contribution to journalArticle

Morphogenesis
Transcription Factors
Mesoderm
Kidney
Down-Regulation
3 Citations (Scopus)

A Fluorometric Method of Measuring Carboxypeptidase Activities for Angiotensin II and Apelin-13

Liu, P., Wysocki, J., Serfozo, P., Ye, M., Souma, T., Batlle, D. & Jin, J., Apr 5 2017, In : Scientific reports. 7, 45473.

Research output: Contribution to journalArticle

Carboxypeptidases
Phenylalanine
Angiotensin II
Proline
Enzymes