Grants per year
Personal profile
Research Interests
The lab is generally interested in the pathological mechanisms of kidney and vascular diseases. We take a proteomic approach to study molecules that serve structural or functional roles in kidney filtration. Particularly, we are trying to understand how the kidney podocytes maintain and regulate their slit diaphragm, as well as their interactions with the glomerular basement membrane.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Biophysics, University of Toronto
… → 2003
MD, Medicine, Peking University
… → 1992
Research interests keywords
- Angiogenesis
- Biochemistry: Proteins
- Cardiovascular Diseases
- Hypertension
- Nephrology
- Proteomics
- Vascular Biology
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Collaborations and top research areas from the last five years
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Rationally Designed, Target-specific Imaging Probe
Jin, J., Zhao, M., Lee, J. & Quaggin, S. E.
National Institute of Biomedical Imaging and Bioengineering
4/15/23 → 2/28/27
Project: Research project
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The role of Angiopoietin-TEK signaling in polypoidal choroidal vasculopathy
Thomson, B. R., Fawzi, A. A. & Jin, J.
6/1/21 → 5/31/26
Project: Research project
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The identification and pathophysiology of non-infarcted but injured myocardium in the post-ischemic heart
Arora, R. K., Zhao, M., Jin, J., Kume, T., Kwasny, M. J. & Lomasney, J. W.
National Heart, Lung, and Blood Institute
1/1/21 → 12/31/24
Project: Research project
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Activation of the Angiopoietin-Tie2/TEK Pathway to Treat Ocular Hypertension and Glaucoma
9/1/20 → 6/30/25
Project: Research project
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A Master Role of Symmetric Arginine Dimethylation in Lupus Autoantibody Response
Jin, J., Ghossein, C., Pope, R. M. & Ramsey-Goldman, R.
National Institute of Allergy and Infectious Diseases
5/15/18 → 4/30/21
Project: Research project
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Activation of Angiopoietin-Tie2 Signaling Protects the Kidney from Ischemic Injury by Modulation of Endothelial-Specific Pathways
Li, Y., Liu, P., Zhou, Y., Maekawa, H., Silva, J. B., Ansari, M. J., Boubes, K., Alia, Y., Deb, D. K., Thomson, B. R., Jin, J. & Quaggin, S. E., Jun 1 2023, In: Journal of the American Society of Nephrology. 34, 6, p. 969-987 19 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Chimeric Fusion between Clostridium Ramosum IgA Protease and IgG Fc Provides Long-Lasting Clearance of IgA Deposits in Mouse Models of IgA Nephropathy
Xie, X., Li, J., Liu, P., Wang, M., Gao, L., Wan, F., Lv, J., Zhang, H. & Jin, J., May 2022, In: Journal of the American Society of Nephrology. 33, 5, p. 918-935 18 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
High-avidity binding drives nucleation of amyloidogenic transthyretin monomer
Gao, L., Xie, X., Liu, P. & Jin, J., Apr 8 2022, In: JCI Insight. 7, 7, e150131.Research output: Contribution to journal › Article › peer-review
Open Access -
Serological Measurement of Poly-IgA Immune Complex Levels in IgA Nephropathy and IgA Vasculitis
Zhang, X., Lv, J., Liu, P., Xie, X., Li, X., Zhang, H. & Jin, J., Jul 5 2022, In: Bio-protocol. 12, 13, e4463.Research output: Contribution to journal › Article › peer-review
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Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies
Thomson, B. R., Liu, P., Onay, T., Du, J., Tompson, S. W., Misener, S., Purohit, R. R., Young, T. L., Jin, J. & Quaggin, S. E., Dec 1 2021, In: Nature communications. 12, 1, 6072.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations
Datasets
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Data from: Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry
Liu, P. (Contributor), Ali, L. (Contributor), Thomson, B. R. (Contributor), Savas, J. N. (Contributor) & Jin, J. (Contributor), ZENODO, Dec 6 2019
DOI: 10.5061/dryad.r6h8dr2, https://zenodo.org/record/5017248
Dataset
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Data from: Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry
Liu, P. (Creator), Ali, L. (Creator), Thomson, B. R. (Creator), Savas, J. N. (Creator) & Jin, J. (Creator), Dryad, Dec 6 2019
DOI: 10.5061/dryad.r6h8dr2, https://datadryad.org/stash/dataset/doi:10.5061/dryad.r6h8dr2
Dataset