Grants per year
Personal profile
Research Interests
The lab is generally interested in the pathological mechanisms of kidney and vascular diseases. We take a proteomic approach to study molecules that serve structural or functional roles in kidney filtration. Particularly, we are trying to understand how the kidney podocytes maintain and regulate their slit diaphragm, as well as their interactions with the glomerular basement membrane.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Biophysics, University of Toronto
… → 2003
MD, Medicine, Peking University
… → 1992
Research interests keywords
- Angiogenesis
- Biochemistry: Proteins
- Cardiovascular Diseases
- Hypertension
- Nephrology
- Proteomics
- Vascular Biology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mosaic Loss of the Y Chromosome in Cardiac Amyloidosis
Jin, J. (PD/PI) & Liu, P. (Other)
University of Virginia, National Institute on Aging
4/15/24 → 1/31/29
Project: Research project
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Rationally Designed, Target-specific Imaging Probe
Jin, J. (PD/PI), Jin, J. (PD/PI), Zhao, M. (PD/PI), Zhao, M. (PD/PI), Lee, J. (Co-Investigator), Quaggin, S. E. (Co-Investigator) & Quaggin, S. E. (Co-Investigator)
National Institute of Biomedical Imaging and Bioengineering
4/15/23 → 2/28/27
Project: Research project
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The role of Angiopoietin-TEK signaling in polypoidal choroidal vasculopathy
Thomson, B. R. (PD/PI), Thomson, B. R. (PD/PI), Fawzi, A. A. (Co-Investigator), Fawzi, A. A. (Co-Investigator), Jin, J. (Co-Investigator) & Jin, J. (Co-Investigator)
6/1/21 → 5/31/26
Project: Research project
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The identification and pathophysiology of non-infarcted but injured myocardium in the post-ischemic heart
Arora, R. K. (PD/PI), Arora, R. K. (PD/PI), Arora, R. K. (PD/PI), Zhao, M. (PD/PI), Zhao, M. (PD/PI), Zhao, M. (PD/PI), Arora, R. K. (Co-PD/PI), Jin, J. (Co-Investigator), Jin, J. (Co-Investigator), Jin, J. (Co-Investigator), Kume, T. (Co-Investigator), Kume, T. (Co-Investigator), Kume, T. (Co-Investigator), Kwasny, M. J. (Co-Investigator), Kwasny, M. J. (Co-Investigator), Kwasny, M. J. (Co-Investigator), Lomasney, J. W. (Co-Investigator), Lomasney, J. W. (Co-Investigator) & Lomasney, J. W. (Co-Investigator)
National Heart, Lung, and Blood Institute
1/1/21 → 12/31/25
Project: Research project
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Activation of the Angiopoietin-Tie2/TEK Pathway to Treat Ocular Hypertension and Glaucoma
Quaggin, S. E. (PD/PI), Quaggin, S. E. (PD/PI), Quaggin, S. E. (PD/PI), Jin, J. (Co-Investigator), Jin, J. (Co-Investigator) & Jin, J. (Co-Investigator)
9/1/20 → 6/30/26
Project: Research project
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Lactobacillus casei Cell Wall Extract and Production of Galactose-Deficient IgA1 in a Humanized IGHA1 Mouse Model
Li, R., Wang, M., Li, J., Zhu, L., Xie, X., Wang, H., Zhang, X., Tian, W., Zhang, Y., Dong, Y., Zan, J., Li, H., Zhang, Y., Zhou, X., Shi, S., Shu, C., Liu, L., Jin, J., Lv, J. & Zhang, H., Jan 1 2025, In: Journal of the American Society of Nephrology. 36, 1, p. 60-72 13 p.Research output: Contribution to journal › Article › peer-review
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Heterozygous mutations in factor H aggravate pathological damage in a stable IgA deposition model induced by Lactobacillus casei cell wall extract
Li, J., Dong, Y., Chen, F., Yang, H., Chen, P., Li, H., Shi, S., Zhou, X., Zhu, L., Zhang, Y., Liu, L., Xie, X., Yu, F., Jin, J., Lv, J. & Zhang, H., 2024, In: Frontiers in immunology. 15, 1368322.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Humoral immune responses primed by the alteration of gut microbiota were associated with galactose-deficient IgA1 production in IgA nephropathy
Gao, L., Li, H., Liu, X., Li, H., Li, P., Lu, W., Xie, X., Lv, J. & Jin, J., 2024, In: Frontiers in immunology. 15, 1415026.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
The mechanosensory channel PIEZO1 functions upstream of angiopoietin/TIE/FOXO1 signaling in lymphatic development
Du, J., Liu, P., Zhou, Y., Misener, S., Sharma, I., Leeaw, P., Thomson, B. R., Jin, J. & Quaggin, S. E., May 15 2024, In: Journal of Clinical Investigation. 134, 10, e176577.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Activation of Angiopoietin-Tie2 Signaling Protects the Kidney from Ischemic Injury by Modulation of Endothelial-Specific Pathways
Li, Y., Liu, P., Zhou, Y., Maekawa, H., Silva, J. B., Ansari, M. J., Boubes, K., Alia, Y., Deb, D. K., Thomson, B. R., Jin, J. & Quaggin, S. E., Jun 1 2023, In: Journal of the American Society of Nephrology. 34, 6, p. 969-987 19 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations
Datasets
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Data from: Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry
Liu, P. (Creator), Ali, L. (Creator), Thomson, B. R. (Creator), Savas, J. N. (Creator) & Jin, J. (Creator), Dryad, Dec 6 2019
DOI: 10.5061/dryad.r6h8dr2, https://datadryad.org/stash/dataset/doi:10.5061/dryad.r6h8dr2
Dataset
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Data from: Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry
Liu, P. (Contributor), Ali, L. (Contributor), Thomson, B. R. (Contributor), Savas, J. N. (Contributor) & Jin, J. (Contributor), ZENODO, Dec 6 2019
DOI: 10.5061/dryad.r6h8dr2, https://zenodo.org/records/5017248
Dataset