Grants per year
Personal profile
Research Interests
Professor Wang’s research interests are in the statistical applications in biology and medical sciences. His recent work concerns developing statistical methods and tools for large-scale, high-dimensional genomic, genetic and human brain mapping data. Some working topics include species number estimation, nucleosome positioning mapping, next-generation sequencing analysis, RNA-seq normalization, fMRI data in human brain mapping, and Bayesian network with applications to The Cancer Genome Atlas (TCGA) data. His lab has developed a few software tools that have been frequently used by researchers, including NuPoP (for nucleosome positioning prediction, see bioconductor) and SPECIES (for species number estimation, see CRAN).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Statistics, PhD, Pennsylvania State University
… → 2003
Statistics, MS, Pennsylvania State University
… → 2000
BS, University of Science and Technology of China
… → 1995
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Collaborations and top research areas from the last five years
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Optogenomic mapping of chromatin accessibility in live cells
Wang, X. (PD/PI), Wang, X. (PD/PI), Vafabakhsh, R. (Co-Investigator), Vafabakhsh, R. (Co-Investigator), Wang, J. (Co-Investigator) & Wang, J. (Co-Investigator)
National Institute of General Medical Sciences
9/24/22 → 7/31/26
Project: Research project
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REU Site: Quantitative Biology REU (QBREU) at Northwestern University
Braun, R. I. (PD/PI), Braun, R. I. (PD/PI), Andersen, E. C. (Co-PD/PI), Andersen, E. C. (Co-PD/PI), Andersen, E. C. (Co-PD/PI), Beitel, G. J. (Co-PD/PI), Allada, R. (Other), Allada, R. (Other), Auffinger, A. (Other), Auffinger, A. (Other), Carthew, R. W. (Other), Carthew, R. W. (Other), Kath, W. L. (Other), Kath, W. L. (Other), Kovacs, I. (Other), Kovacs, I. (Other), LaBonne, C. (Other), LaBonne, C. (Other), Lane, K. M. (Other), Lane, K. M. (Other), Mangan, N. M. (Other), Mangan, N. M. (Other), Mani, M. (Other), Mani, M. (Other), Wang, J. (Other) & Wang, J. (Other)
4/15/22 → 3/31/25
Project: Research project
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Molecular Targets of Aging-Triggered Memory Decline in a Stress-Reactive Rat Strain
Redei, E. E. (PD/PI) & Wang, J. (PD/PI)
9/15/20 → 8/31/22
Project: Research project
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Northwestern University Quantitative Biology Center (NUQuB)
Carthew, R. W. (PD/PI), Allada, R. (Co-Investigator), Amaral, L. A. N. (Co-Investigator), Andersen, E. C. (Co-Investigator), Auffinger, A. (Co-Investigator), Bagheri, N. (Co-Investigator), Braun, R. I. (Co-Investigator), Kath, W. L. (Co-Investigator), LaBonne, C. (Co-Investigator), Mangan, N. M. (Co-Investigator), Mani, M. (Co-Investigator), Wang, J. (Co-Investigator), Wang, X. (Co-Investigator) & Goldberg, B. B. (Other)
7/1/18 → 6/30/24
Project: Research project
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Northwestern University Quantitative Biology Center (NUQuB)
Carthew, R. W. (PD/PI), Allada, R. (Co-PD/PI), Amaral, L. A. N. (Co-PD/PI), Andersen, E. C. (Co-PD/PI), Kath, W. L. (Co-PD/PI), Allada, R. (Co-Investigator), Amaral, L. A. N. (Co-Investigator), Andersen, E. C. (Co-Investigator), Auffinger, A. (Co-Investigator), Bagheri, N. (Co-Investigator), Braun, R. I. (Co-Investigator), LaBonne, C. (Co-Investigator), Mangan, N. M. (Co-Investigator), Mani, M. (Co-Investigator), Wang, J. (Co-Investigator) & Wang, X. (Co-Investigator)
7/1/18 → 6/30/24
Project: Research project
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BoostMEC: predicting CRISPR-Cas9 cleavage efficiency through boosting models
Zarate, O. A., Yang, Y., Wang, X. & Wang, J. P., Dec 2022, In: BMC bioinformatics. 23, 1, 446.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
DNAcycP: a deep learning tool for DNA cyclizability prediction
Li, K., Carroll, M., Vafabakhsh, R., Wang, X. A. & Wang, J. P., Apr 8 2022, In: Nucleic acids research. 50, 6, p. 3142-3154 13 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
RiboDiPA: A novel tool for differential pattern analysis in Ribo-seq data
Li, K., Hope, C. M., Wang, X. A. & Wang, J. P., Dec 2 2021, In: Nucleic acids research. 48, 21, p. 12016-12029 14 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Generative data augmentation for commonsense reasoning
Yang, Y., Malaviya, C., Fernandez, J., Swayamdipta, S., Le Bras, R., Wang, J. P., Bhagavatula, C., Choi, Y. & Downey, D., 2020, Findings of the Association for Computational Linguistics Findings of ACL: EMNLP 2020. Association for Computational Linguistics (ACL), p. 1008-1025 18 p. (Findings of the Association for Computational Linguistics Findings of ACL: EMNLP 2020).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
102 Scopus citations -
Mobilizable antibiotic resistance genes are present in dust microbial communities
Maamar, S. B., Glawe, A. J., Brown, T. K., Hellgeth, N., Hu, J., Wang, J. P., Huttenhower, C. & Hartmann, E. M., 2020, In: PLoS pathogens. 16, 1, e1008211.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations
Datasets
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Processed data - DegNorm: Normalization of generalized transcript degradation improves accuracy in RNA-seq analysis
Xiong, B. (Contributor), Yang, Y. (Contributor), Fineis, F. R. (Contributor) & Wang, J.-P. (Contributor), ZENODO, Mar 19 2019
DOI: 10.5281/zenodo.2595303, https://zenodo.org/record/2595303
Dataset
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A map of nucleosome positions in yeast at base-pair resolution
Brogaard, K. (Contributor), Xi, L. (Contributor), Wang, J.-P. (Contributor) & Widom, J. (Contributor), Gene Expression Omnibus, Feb 24 2012
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE36063
Dataset
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Data from: Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory
D’Urso, A. (Contributor), Takahashi, Y.-H. (Creator), Xiong, B. (Creator), Marone, J. (Creator), Coukos, R. (Creator), Randise-Hinchliff, C. (Creator), Wang, J.-P. (Creator), Shilatifard, A. (Creator) & Brickner, J. H. (Creator), Dryad, Jul 7 2016
DOI: 10.5061/dryad.93fv2, https://datadryad.org/stash/dataset/doi:10.5061/dryad.93fv2
Dataset
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Simulation data and code for analysis - DegNorm: Normalization of generalized transcript degradation improves accuracy in RNA-seq analysis
Xiong, B. (Contributor), Yang, Y. (Contributor), Fineis, F. R. (Contributor) & Wang, J.-P. (Contributor), ZENODO, Mar 19 2019
DOI: 10.5281/zenodo.2595559, https://zenodo.org/record/2595559
Dataset
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Additional file 4: of DegNorm: normalization of generalized transcript degradation improves accuracy in RNA-seq analysis
Xiong, B. (Creator), Yang, Y. (Contributor), Fineis, F. R. (Creator) & Wang, J.-P. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.8002913, https://springernature.figshare.com/articles/dataset/Additional_file_4_of_DegNorm_normalization_of_generalized_transcript_degradation_improves_accuracy_in_RNA-seq_analysis/8002913
Dataset