Grants per year
Personal profile
Research Interests
I am a clinical trialist / study design specialist; my research interests include clinical study design and conduct, database development and data (quality) monitoring, interim monitoring / reporting / analyses, randomization and treatment allocation techniques (including cluster-randomization allocation techniques), and clinical trial data analyses. My applied / collaborative research focuses on clinical studies applied to a wide range of disorders, diseases, and populations including those in the fields of perinatal depression, mood disorders, internal medicine and geriatrics, gastroenterology, and pediatrics. I also teach in the MS-Biostatistics program which includes: directing the concentration for Statistical Methods and Practice, coordinating the thesis efforts and corresponding thesis course, and teaching the clinical database management course.
Education/Academic qualification
PhD, Biostatistics, Medical University of South Carolina
… → 2011
MS, Biostatistics, Medical University of South Carolina
… → 2009
Research interests keywords
- Biostatistics
- Clinical Research
- Clinical Trial Methodology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy for Back Pain
Ciolino, J. D. (PD/PI), Kim, H. (PD/PI), McCarthy, D. M. (Co-Investigator) & Schauer, J. M. (Co-Investigator)
National Center for Complementary and Integrative Health
8/15/24 → 7/31/27
Project: Research project
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PREcision MEDicine In Achalasia--PREMEDIA
Pandolfino, J. E. (PD/PI), Pandolfino, J. E. (PD/PI), Schauer, J. M. (PD/PI), Schauer, J. M. (PD/PI), Ciolino, J. D. (Co-Investigator) & Ciolino, J. D. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
9/1/23 → 8/31/25
Project: Research project
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A double-blind randomized controlled trial to assess the effectiveness and tolerability of a quadruple ultra-low-dose treatment for hypertension (QUARTET)
Ciolino, J. D. (PD/PI), Ciolino, J. D. (PD/PI), Kandula, N. R. (Co-Investigator), Kandula, N. R. (Co-Investigator), Khan, S. S. (Co-Investigator), Khan, S. S. (Co-Investigator), Lloyd-Jones, D. M. (Co-Investigator), Lloyd-Jones, D. M. (Co-Investigator), Paparello, J. J. (Co-Investigator) & Paparello, J. J. (Co-Investigator)
Washington University in St. Louis, National Heart, Lung, and Blood Institute
8/9/22 → 7/31/25
Project: Research project
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Central Biorepository Subproject for SP0065429
Ciolino, J. D. (PD/PI), Ciolino, J. D. (PD/PI), Pinelli, D. (PD/PI), Ladner, D. P. (Co-PD/PI) & Ladner, D. P. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
8/28/21 → 7/31/26
Project: Research project
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Liver Cirrhosis Network: Scientific and Data Coordination Center
Ciolino, J. D. (PD/PI), Ciolino, J. D. (PD/PI), Ladner, D. P. (PD/PI), Ladner, D. P. (PD/PI), Ladner, D. P. (Co-PD/PI), Bonner, L. B. (Co-Investigator), Bonner, L. B. (Co-Investigator), Lloyd-Jones, D. M. (Co-Investigator), Lloyd-Jones, D. M. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Scholtens, D. M. (Co-Investigator), VanWagner, L. B. (Co-Investigator) & VanWagner, L. B. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
8/28/21 → 7/31/26
Project: Research project
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Changes in S-Citalopram Plasma Concentrations Across Pregnancy and Postpartum
Stika, C. S., Avram, M. J., George, A. L., Yang, A., Ciolino, J. D., Jeong, H., Venkataramanan, R., Caritis, S. N., Costantine, M. M. & Wisner, K. L., 2025, (Accepted/In press) In: Clinical pharmacology and therapeutics.Research output: Contribution to journal › Article › peer-review
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Factorial Clinical Trial Designs
Ciolino, J. D., Scholtens, D. M. & Bonner, L. B., Feb 11 2025, In: JAMA. 333, 6, p. 532-533 2 p.Research output: Contribution to journal › Review article › peer-review
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Challenges of Families of Patients Hospitalized in the PICU: A Preplanned Secondary Analysis from the Navigate Dataset∗
Tager, J. B., Hinojosa, J. T., Liabraaten, B. M., Balistreri, K. A., Aniciete, D., Charleston, E., Frader, J. E., White, D. B., Clayman, M. L., Sorce, L. R., Davies, W. H., Rothschild, C. B., Michelson, K. N., White, D., Brown, M., Fragen, P., Ciolino, J., Rychlik, K., Persell, S. & Victorson, D. & 23 others, , Feb 1 2024, In: Pediatric Critical Care Medicine. 25, 2, p. 128-138 11 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Efficacy and safety of a four-drug, quarter-dose treatment for hypertension: the QUARTET USA randomized trial
Huffman, M. D., Baldridge, A. S., Lazar, D., Abbas, H., Mejia, J., Flowers, F. M., Quintana, A., Jackson, A., Kandula, N. R., Lloyd-Jones, D. M., Persell, S. D., Khan, S. S., Paparello, J. J., Chopra, A., Tripathi, P., Vu, M. H., Chow, C. K. & Ciolino, J. D., Jun 2024, In: Hypertension Research. 47, 6, p. 1668-1677 10 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Erratum: Correction: Temporal changes in the systemic concentrations of retinoids in pregnant and postpartum women (PloS one (2023) 18 2 DOI: 10.1371/journal.pone.0280424)
Jeong, H., Czuba, L., Isoherranen, N., Armstrong, A. T., Yang, A., Zumpf, K., Ciolino, J., Torres, E., Stika, C. S. & Wisner, K. L., 2024, In: PloS one. 19, 11, p. e0314399Research output: Contribution to journal › Comment/debate › peer-review
Open Access
Datasets
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Ideal vs. real: a systematic review on handling covariates in randomized controlled trials
Ciolino, J. D. (Creator), Palac, H. L. (Creator), Yang, A. (Creator), Vaca, M. (Creator) & Belli, H. M. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4565261, https://springernature.figshare.com/collections/Ideal_vs_real_a_systematic_review_on_handling_covariates_in_randomized_controlled_trials/4565261
Dataset
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Testing the effects of a prenatal depression preventive intervention on parenting and young children’s self-regulation and functioning (EPIC): protocol for a longitudinal observational study
Diebold, A. (Creator), Johnson, J. K. (Creator), Brennan, M. (Creator), Ciolino, J. D. (Creator), Petitclerc, A. (Creator), Wakschlag, L. S. (Creator), Garfield, C. F. (Creator), Yeh, C. (Creator), Lovejoy, A. (Creator), Zakieh, D. (Creator) & Tandon, S. D. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5507052, https://springernature.figshare.com/collections/Testing_the_effects_of_a_prenatal_depression_preventive_intervention_on_parenting_and_young_children_s_self-regulation_and_functioning_EPIC_protocol_for_a_longitudinal_observational_study/5507052
Dataset
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Choosing an imbalance metric for covariate-constrained randomization in multiple-arm cluster-randomized trials
Ciolino, J. D. (Creator), Diebold, A. (Creator), Jensen, J. K. (Creator), Rouleau, G. W. (Creator), Koloms, K. K. (Creator) & Tandon, D. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4520951, https://springernature.figshare.com/collections/Choosing_an_imbalance_metric_for_covariate-constrained_randomization_in_multiple-arm_cluster-randomized_trials/4520951
Dataset