Grants per year
Personal profile
Research Interests
We are using single photon confocal microscopy to measure intracellular Ca cycling in individual myocytes of intact rat and mouse hearts. Hearts are loaded with the Ca indicator fluo-4AM, allowing us to measure intracellular Ca at the submicron level. Ongoing projects include study of changes in Ca cycling in animal models of heart failure, catecholaminergic polymorphic ventricular tachycardia, spontaneous Ca release and cardiac arrhythmias.
Training Experience
| 1981 | Postdoctoral Fellowship, University of Chicago |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, SUNY - Syracuse
… → 1978
Research interests
- Biophysics
- Cardiovascular Diseases
- Cell Imaging
- Pharmacology
- Physiology
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Understanding Calmodulinopathies in an Animal Model
George, A. L., Kearney, J. A. & Wasserstrom, J. A.
7/1/17 → 6/30/19
Project: Research project
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Determinants, Trajectories, and Consequences of Abnormal Cardiac Mechanics
Shah, S. J., Rasmussen-Torvik, L. J. & Wasserstrom, J. A.
National Heart, Lung, and Blood Institute
7/5/16 → 4/30/22
Project: Research project
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Role of PIP2 and Bin1 in T-tubule Remodeling During Heart Failure Development
American Heart Association Midwest Affiliate
6/1/16 → 8/31/16
Project: Research project
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Atrial arrhythmias and Ca2+ waves in HF: simulation and experimental studies
Wasserstrom, J. A. & Aistrup, G. L.
National Heart, Lung, and Blood Institute
9/1/14 → 5/31/20
Project: Research project
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Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects
Barefield, D. Y., Yamakawa, S., Tahtah, I., Sell, J. J., Broman, M., Laforest, B., Harris, S., Alvarez-Arce, A., Araujo, K. N., Puckelwartz, M. J., Wasserstrom, J. A., Fishman, G. I. & McNally, E. M., Aug 2022, In: Journal of Molecular and Cellular Cardiology. 169, p. 28-40 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Voltage-mediated mechanism for calcium wave synchronization and arrhythmogenesis in atrial tissue
Greene, DA. A., Kaboudian, A., Wasserstrom, J. A., Fenton, F. H. & Shiferaw, Y., Feb 1 2022, In: Biophysical Journal. 121, 3, p. 383-395 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Bone marrow-derived AXL tyrosine kinase promotes mitogenic crosstalk and cardiac allograft vasculopathy
Glinton, K., DeBerge, M., Fisher, E., Schroth, S., Sinha, A., Wang, J. J., Wasserstrom, J. A., Ansari, M. J., Zhang, Z. J., Feinstein, M., Leventhal, J. R., Forbess, J. M., Lomasney, J., Luo, X. & Thorp, E. B., Jun 2021, In: Journal of Heart and Lung Transplantation. 40, 6, p. 435-446 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Phosphatidylinositol-4,5-Bisphosphate Binding to Amphiphysin-II Modulates T-Tubule Remodeling: Implications for Heart Failure
Zhou, J., Singh, N., Monnier, C., Marszalec, W., Gao, L., Jin, J., Frisk, M., Louch, W. E., Verma, S., Krishnamurthy, P., Nico, E., Mulla, M., Aistrup, G. L., Kishore, R. & Wasserstrom, J. A., Dec 23 2021, In: Frontiers in Physiology. 12, 782767.Research output: Contribution to journal › Article › peer-review
Open Access -
Role of t-tubule remodeling on mechanisms of abnormal calcium release during heart failure development in canine ventricle
Yamakawa, S., Wu, D., Dasgupta, M., Pedamallu, H., Gupta, B., Modi, R., Mufti, M., OCallaghan, C., Frisk, M., Louch, W. E., Arora, R., Shiferaw, Y., Burrell, A., Ryan, J., Nelson, L., Chow, M., Shah, S. J., Aistrup, G. L., Zhou, J., Marszalec, W., & 1 others, Apr 2021, In: American Journal of Physiology - Heart and Circulatory Physiology. 320, 4, p. H1658-H1669Research output: Contribution to journal › Article › peer-review
1 Scopus citations