John A Wasserstrom

  • 2598 Citations
1979 …2020

Research output per year

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Personal profile

Research Interests

We are using single photon confocal microscopy to measure intracellular Ca cycling in individual myocytes of intact rat and mouse hearts. Hearts are loaded with the Ca indicator fluo-4AM, allowing us to measure intracellular Ca at the submicron level. Ongoing projects include study of changes in Ca cycling in animal models of heart failure, catecholaminergic polymorphic ventricular tachycardia, spontaneous Ca release and cardiac arrhythmias.

Training Experience

1981Postdoctoral Fellowship, University of Chicago

Education/Academic qualification

PhD, SUNY - Syracuse

… → 1978

Research interests

  • Biophysics
  • Cardiovascular Diseases
  • Cell Imaging
  • Pharmacology
  • Physiology

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Grants

  • Research Output

    • 2598 Citations
    • 88 Article
    • 6 Review article
    • 3 Comment/debate

    Remodeling Promotes Proarrhythmic Disruption of Calcium Homeostasis in Failing Atrial Myocytes

    Shiferaw, Y., Aistrup, G. L., Louch, W. E. & Wasserstrom, J. A., Jan 21 2020, In : Biophysical Journal. 118, 2, p. 476-491 16 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    The sodium channel NaX: Possible player in excitation–contraction coupling

    Bogdanovic, E., Potet, F., Marszalec, W., Iyer, H., Galiano, R., Hong, S. J., Leung, K. P., Wasserstrom, J. A., George, A. L. & Mustoe, T. A., Apr 1 2020, In : IUBMB Life. 72, 4, p. 601-606 6 p.

    Research output: Contribution to journalArticle

  • Triggered Ca2+ Waves Induce Depolarization of Maximum Diastolic Potential and Action Potential Prolongation in Dog Atrial Myocytes

    Gussak, G., Marszalec, W., Yoo, S., Modi, R., O'Callaghan, C., Aistrup, G. L., Cordeiro, J. M., Goodrow, R., Kanaporis, G., Blatter, L. A., Shiferaw, Y., Arora, R., Zhou, J., Burrell, A. R. & Wasserstrom, J. A., Jun 1 2020, In : Circulation. Arrhythmia and electrophysiology. 13, 6, p. e008179

    Research output: Contribution to journalArticle

  • Oxidative stress creates a unique, CaMKII-mediated substrate for atrial fibrillation in heart failure

    Yoo, S., Aistrup, G. L., Shiferaw, Y., Ng, J., Mohler, P. J., Hund, T. J., Waugh, T., Browne, S., Gussak, G., Gilani, M., Knight, B. P., Passman, R., Goldberger, J. J., Wasserstrom, J. A. & Arora, R., Nov 2 2018, In : JCI insight. 3, 21

    Research output: Contribution to journalArticle

    Open Access
  • 6 Scopus citations

    Synchronization of Triggered Waves in Atrial Tissue

    Shiferaw, Y., Aistrup, G. L. & Wasserstrom, J. A., Sep 18 2018, In : Biophysical Journal. 115, 6, p. 1130-1141 12 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations