Grants per year
Personal profile
Research Interests
We are using single photon confocal microscopy to measure intracellular Ca cycling in individual myocytes of intact rat and mouse hearts. Hearts are loaded with the Ca indicator fluo-4AM, allowing us to measure intracellular Ca at the submicron level. Ongoing projects include study of changes in Ca cycling in animal models of heart failure, catecholaminergic polymorphic ventricular tachycardia, spontaneous Ca release and cardiac arrhythmias.
Training Experience
| 1981 | Postdoctoral Fellowship, University of Chicago |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Pharmacology, SUNY - Syracuse
… → 1978
Research interests keywords
- Biophysics
- Cardiovascular Diseases
- Cell Imaging
- Pharmacology
- Physiology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Role of Endothelin-1 signaling in the development and progression of atrial fibrillation
Pfenniger, A., Arora, R. K., George, A. L., Lee, D. C., Passman, R. S., Roy-Puckelwartz, M. J., Shah, S. J., Vaughan, D. E. & Wasserstrom, J. A.
National Heart, Lung, and Blood Institute
9/1/23 → 8/31/28
Project: Research project
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Understanding Calmodulinopathies in an Animal Model
George, A. L., Kearney, J. A. & Wasserstrom, J. A.
7/1/17 → 6/30/19
Project: Research project
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Determinants, Trajectories, and Consequences of Abnormal Cardiac Mechanics
Shah, S. J., Rasmussen-Torvik, L. J. & Wasserstrom, J. A.
National Heart, Lung, and Blood Institute
7/5/16 → 4/30/22
Project: Research project
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Role of PIP2 and Bin1 in T-tubule Remodeling During Heart Failure Development
American Heart Association Midwest Affiliate
6/1/16 → 8/31/16
Project: Research project
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BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
Perdreau-Dahl, H., Lipsett, D. B., Frisk, M., Kermani, F., Carlson, C. R., Brech, A., Shen, X., Bergan-Dahl, A., Hou, Y., Tuomainen, T., Tavi, P., Jones, P. P., Lunde, M., Wasserstrom, J. A., Laporte, J., Ullrich, N. D., Christensen, G., Morth, J. P. & Louch, W. E., May 26 2023, In: Circulation research. 132, 11, p. E188-E205Research output: Contribution to journal › Article › peer-review
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Regions of Highly Recurrent Electrogram Morphology With Low Cycle Length Reflect Substrate for Atrial Fibrillation
Yoo, S., Rottmann, M., Ng, J., Johnson, D., Shanab, B., Pfenniger, A., Geist, G. E., Mandava, S., Burrell, A., Zhang, W., Wasserstrom, J. A., Knight, B. P., Passman, R., Goldberger, J. J. & Arora, R., Jan 2023, In: JACC: Basic to Translational Science. 8, 1, p. 68-84 17 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects
Barefield, D. Y., Yamakawa, S., Tahtah, I., Sell, J. J., Broman, M., Laforest, B., Harris, S., Alvarez-Arce, A., Araujo, K. N., Puckelwartz, M. J., Wasserstrom, J. A., Fishman, G. I. & McNally, E. M., Aug 2022, In: Journal of Molecular and Cellular Cardiology. 169, p. 28-40 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Voltage-mediated mechanism for calcium wave synchronization and arrhythmogenesis in atrial tissue
Greene, DA. A., Kaboudian, A., Wasserstrom, J. A., Fenton, F. H. & Shiferaw, Y., Feb 1 2022, In: Biophysical Journal. 121, 3, p. 383-395 13 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Bone marrow-derived AXL tyrosine kinase promotes mitogenic crosstalk and cardiac allograft vasculopathy
Glinton, K., DeBerge, M., Fisher, E., Schroth, S., Sinha, A., Wang, J. J., Wasserstrom, J. A., Ansari, M. J., Zhang, Z. J., Feinstein, M., Leventhal, J. R., Forbess, J. M., Lomasney, J., Luo, X. & Thorp, E. B., Jun 2021, In: Journal of Heart and Lung Transplantation. 40, 6, p. 435-446 12 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations