John F Disterhoft

  • 13124 Citations
1968 …2024
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Research Output 1968 2019

Article
51 Citations (Scopus)

Accessory abducens nucleus and conditioned eye retraction/nictitating membrane extension in rabbit

Disterhoft, J. F., Quinn, K. J., Weiss, C. & Shipley, M. T., Jan 1 1985, In : Journal of Neuroscience. 5, 4, p. 941-950 10 p.

Research output: Contribution to journalArticle

Nictitating Membrane
Oculomotor Muscles
Rabbits
Motor Neurons
Horseradish Peroxidase
83 Citations (Scopus)

Activation of metabotropic glutamate receptors induces long-term depression of GABAergic inhibition in hippocampus

Liu, Y. B., Disterhoft, J. F. & Slater, N. T., Jan 1 1993, In : Journal of Neurophysiology. 69, 3, p. 1000-1004 5 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Hippocampus
Synaptic Potentials
Baths
Excitatory Postsynaptic Potentials
4 Citations (Scopus)
Manganese
Magnetic Resonance Imaging
Rabbits
Vibrissae
Somatosensory Cortex
81 Citations (Scopus)

Activity of hippocampal pyramidal neurons during trace eyeblink conditioning

Weiss, C., Kronforst-Collins, M. A. & Disterhoft, J. F., Jul 25 1996, In : Hippocampus. 6, 2, p. 192-209 18 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Neurons
Rabbits
Young Adult
67 Citations (Scopus)
Gyrus Cinguli
Rabbits
Neurons
Signal-To-Noise Ratio
Brain Stem
32 Citations (Scopus)

Acute stress facilitates trace eyeblink conditioning in C57BL/6 male mice and increases the excitability of their CA1 pyramidal neurons

Weiss, C., Sametsky, E., Sasse, A., Spiess, J. & Disterhoft, J. F., Mar 1 2005, In : Learning and Memory. 12, 2, p. 138-143 6 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Shock
Corticosterone
Conditioning (Psychology)
Tail
11 Citations (Scopus)

A fiber optic-based system for behavioral eyeblink measurement in a MRI environment

Miller, M. J., Li, L., Weiss, C., Disterhoft, J. F. & Wyrwicz, A. M., Jan 30 2005, In : Journal of Neuroscience Methods. 141, 1, p. 83-87 5 p.

Research output: Contribution to journalArticle

Myelinated Nerve Fibers
Echo-Planar Imaging
Aptitude
Artifacts
Magnetic Resonance Imaging
52 Citations (Scopus)

Age- and dose-dependent facilitation of associative eyeblink conditioning by D-cycloserine in rabbits

Thompson, L. T. & Disterhoft, J. F., Dec 1 1997, In : Behavioral Neuroscience. 111, 6, p. 1303-1312 10 p.

Research output: Contribution to journalArticle

Cycloserine
N-Methyl-D-Aspartate Receptors
Learning
Rabbits
Glycine
19 Citations (Scopus)

Age-dependent changes in the immunoreactivity for neurofilaments in rabbit hippocampus

Van Der Zee, E. A., Naber, P. A. & Disterhoft, J. F., Apr 28 1997, In : Neuroscience. 79, 1, p. 103-116 14 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Hippocampus
Rabbits
Learning Disorders
Interneurons
16 Citations (Scopus)

Age-related deficits in a forebrain-dependent task, trace-eyeblink conditioning

Galvez, R., Cua, S. & Disterhoft, J. F., Oct 1 2011, In : Neurobiology of Aging. 32, 10, p. 1915-1922 8 p.

Research output: Contribution to journalArticle

Vibrissae
Prosencephalon
Aptitude
Neocortex
Learning
56 Citations (Scopus)

Age-related effects on eyeblink conditioning in the F344 × BN F1 hybrid rat

Knuttinen, M. G., Gamelli, A. E., Weiss, C., Power, J. M. & Disterhoft, J. F., Jan 1 2001, In : Neurobiology of Aging. 22, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Learning
Norway
Rabbits
Conditioning (Psychology)
121 Citations (Scopus)

Age-related enhancement of the slow outward calcium-activated potassium current in hippocampal CA1 pyramidal neurons in vitro

Power, J. M., Wu, W. W., Sametsky, E., Oh, M. M. & Disterhoft, J. F., Aug 15 2002, In : Journal of Neuroscience. 22, 16, p. 7234-7243 10 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Potassium
Calcium
Neurons
Learning
7 Citations (Scopus)

Age-related impairments on one hippocampal-dependent task predict impairments on a subsequent hippocampal-dependent task

Curlik, D. M., Weiss, C., Nicholson, D. A. & Disterhoft, J. F., Jan 1 2014, In : Behavioral Neuroscience. 128, 6, p. 676-688 13 p.

Research output: Contribution to journalArticle

Learning
Water
Aptitude
Hippocampus
Conditioning (Psychology)
54 Citations (Scopus)

Age-related loss of calcium binding proteins in rabbit hippocampus

De Jong, G. I., Naber, P. A., Van Der Zee, E. A., Thompson, L. T., Disterhoft, J. F. & Luiten, P. G. M., Jan 1 1996, In : Neurobiology of Aging. 17, 3, p. 459-465 7 p.

Research output: Contribution to journalArticle

Calbindins
Calcium-Binding Proteins
Hippocampus
Rabbits
Parvalbumins
125 Citations (Scopus)

Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum

Geinisman, Y., Ganeshina, O., Yoshida, R., Berry, R. W., Disterhoft, J. F. & Gallagher, M., Jan 1 2004, In : Neurobiology of Aging. 25, 3, p. 407-416 10 p.

Research output: Contribution to journalArticle

Hippocampal CA1 Region
Synapses
Learning
Young Adult
Spatial Learning
63 Citations (Scopus)

Aging and learning-specific changes in single-neuron activity in CA1 hippocampus during rabbit trace eyeblink conditioning

Mcechron, M. D., Weible, A. P. & Disterhoft, J. F., Oct 22 2001, In : Journal of Neurophysiology. 86, 4, p. 1839-1857 19 p.

Research output: Contribution to journalArticle

Hippocampus
Pyramidal Cells
Learning
Rabbits
Neurons
29 Citations (Scopus)

Aging-related alterations in the distribution of Ca2+-dependent PKC isoforms in rabbit hippocampus

Van de Zee, E. A., Palm, I. F., O'Connor, M., Maizels, E. T., Hunzicker-Dunn, M. & Disterhoft, J. F., Nov 29 2004, In : Hippocampus. 14, 7, p. 849-860 12 p.

Research output: Contribution to journalArticle

Hippocampus
Protein Isoforms
Rabbits
Interneurons
Proteins
37 Citations (Scopus)

Aging-related hyperexcitability in CA3 pyramidal neurons is mediated by enhanced A-type K+ channel function and expression

Simkin, D., Hattori, S., Ybarra, N., Musia, T. F., Buss, E. W., Richter, H., Oh, M. M., Nicholson, D. A. & Disterhoft, J. F., Sep 23 2015, In : Journal of Neuroscience. 35, 38, p. 13206-13218 13 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Action Potentials
Cognition
Hippocampus
Western Blotting

Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression

Simkin, D., Hattori, S., Ybarra, N., Musial, T. F., Buss, E. W., Richter, H., Oh, M. M., Nicholson, D. A. & Disterhoft, J. F., Sep 23 2015, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 38, p. 13206-13218 13 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Action Potentials
Neurons
Cognition
Hippocampus
70 Citations (Scopus)

AHP reductions in rabbit hippocampal neurons during conditioning correlate with acquisition of the learned response

Disterhoft, J. F., Golden, D. T., Read, H. L., Coulter, D. A. & Alkon, D. L., Oct 11 1988, In : Brain research. 462, 1, p. 118-125 8 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Rabbits
Neurons
Membrane Potentials
Action Potentials
39 Citations (Scopus)

Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons

Oh, M. M., Oliveira, F. A., Waters, J. & Disterhoft, J. F., May 10 2013, In : Journal of Neuroscience. 33, 18, p. 7905-7911 7 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Calcium
Neurons
Age Factors
Photons
7 Citations (Scopus)

A MRI-compatible system for whisker stimulation

Li, L., Weiss, C., Talk, A. C., Disterhoft, J. F. & Wyrwicz, A. M., Apr 15 2012, In : Journal of Neuroscience Methods. 205, 2, p. 305-311 7 p.

Research output: Contribution to journalArticle

Vibrissae
Magnetic Resonance Imaging
Vibration
Magnets
Head

Analysis of neuro-behavioral Discovery(TM) data on the Macintosh computer

Akhavein, R., Weiss, C., Larson, C. & Disterhoft, J. F., Dec 28 1996, In : Journal of Neuroscience Methods. 70, 2, p. 131-140 10 p.

Research output: Contribution to journalArticle

Software
Information Storage and Retrieval
Data Display
Aptitude
Technology
8 Citations (Scopus)

An analysis of leg position learning in the cockroach yoked control

Disterhoft, J. F., Haggerty, R. & Corning, W. C., Jan 1 1971, In : Physiology and Behavior. 7, 3, p. 359-362 4 p.

Research output: Contribution to journalArticle

Cockroaches
Leg
Learning
Shock
18 Citations (Scopus)
Vibrissae
Neuronal Plasticity
Prosencephalon
Rodentia
Shock
20 Citations (Scopus)

Apamin increases excitability of CA1 hippocampal pyramidal neurons

Oh, M. M., Power, J. M., Thompson, L. T. & Disterhoft, J. F., Dec 13 2000, In : Neuroscience Research Communications. 27, 2, p. 135-142 8 p.

Research output: Contribution to journalArticle

Apamin
Pyramidal Cells
Bee Venoms
Neurotoxins
Baths
6 Citations (Scopus)

Associative learning down-regulates PKCβ2- and γ-immunoreactivity in astrocytes

Van Der Zee, E. A., Kronforst-Collins, M. A. & Disterhoft, J. F., Jan 1 1996, In : Neuroreport. 7, 15-17, p. 2753-2756 4 p.

Research output: Contribution to journalArticle

Astrocytes
Down-Regulation
Learning
Hippocampus
Rabbits
192 Citations (Scopus)

Associative learning elicits the formation of multiple-synapse boutons

Geinisman, Y., Berry, R. W., Disterhoft, J. F., Power, J. M. & Van Der Zee, E. A., Aug 1 2001, In : Journal of Neuroscience. 21, 15, p. 5568-5573 6 p.

Research output: Contribution to journalArticle

Synapses
Learning
Spine
Hippocampus
Rabbits
67 Citations (Scopus)

A system for quantitative analysis of associative learning. Part 1. Hardware interfaces with cross-species applications

Thompson, L. T., Moyer, J. R., Akase, E. & Disterhoft, J. F., Jan 1 1994, In : Journal of Neuroscience Methods. 54, 1, p. 109-117 9 p.

Research output: Contribution to journalArticle

Classical Conditioning
Learning
Nictitating Membrane
Microcomputers
Software
39 Citations (Scopus)

A system for quantitative analysis of associative learning. Part 2. Real-time software for MS-DOS microcomputers

Akase, E., Thompson, L. T. & Disterhoft, J. F., Jan 1 1994, In : Journal of Neuroscience Methods. 54, 1, p. 119-130 12 p.

Research output: Contribution to journalArticle

Microcomputers
Software
Learning
Classical Conditioning
Cohort Studies
10 Citations (Scopus)

Autophosphorylation of αCaMKII downregulates excitability of CA1 pyramidal neurons following synaptic stimulation

Sametsky, E. A., Disterhoft, J. F. & Ohno, M., Jul 1 2009, In : Neurobiology of Learning and Memory. 92, 1, p. 120-123 4 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Pyramidal Cells
Down-Regulation
Learning
Neurons
72 Citations (Scopus)

Awareness in classical differential eyeblink conditioning in young and aging humans

Knuttinen, M. G., Power, J. M., Preston, A. R. & Disterhoft, J. F., Aug 22 2001, In : Behavioral Neuroscience. 115, 4, p. 747-757 11 p.

Research output: Contribution to journalArticle

Motion Pictures
Population
Discrimination (Psychology)
Conditioning (Psychology)
Learning
417 Citations (Scopus)

BACE1 Deficiency Rescues Memory Deficits and Cholinergic Dysfunction in a Mouse Model of Alzheimer's Disease

Ohno, M., Sametsky, E. A., Younkin, L. H., Oakley, H., Younkin, S. G., Citron, M., Vassar, R. & Disterhoft, J. F., Jan 8 2004, In : Neuron. 41, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

Memory Disorders
Cholinergic Agents
Alzheimer Disease
Amyloid
Amyloid Precursor Protein Secretases
195 Citations (Scopus)

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

Ohno, M., Cole, S. L., Yasvoina, M., Zhao, J., Citron, M., Berry, R., Disterhoft, J. F. & Vassar, R., Apr 1 2007, In : Neurobiology of Disease. 26, 1, p. 134-145 12 p.

Research output: Contribution to journalArticle

Memory Disorders
Gene Deletion
Transgenic Mice
Alzheimer Disease
Neurons
241 Citations (Scopus)

Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry

Bond, A. M., Vangompel, M. J. W., Sametsky, E. A., Clark, M. F., Savage, J. C., Disterhoft, J. F. & Kohtz, J., Aug 1 2009, In : Nature Neuroscience. 12, 8, p. 1020-1027 8 p.

Research output: Contribution to journalArticle

Untranslated RNA
Interneurons
Prosencephalon
gamma-Aminobutyric Acid
Hippocampus
57 Citations (Scopus)
Thyroid Hormones
Alcohols
Mothers
Therapeutics
GAP-43 Protein
30 Citations (Scopus)

Blocking the BK channel impedes acquisition of trace eyeblink conditioning

Matthews, E. A. & Disterhoft, J. F., Feb 1 2009, In : Learning and Memory. 16, 2, p. 106-109 4 p.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Learning
Action Potentials
Hippocampus
Conditioning (Psychology)
63 Citations (Scopus)

BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice

Gobeske, K. T., Das, S., Bonaguidi, M. A., Weiss, C., Radulovic, J., Disterhoft, J. F. & Kessler, J., Oct 20 2009, In : PloS one. 4, 10, e7506.

Research output: Contribution to journalArticle

bone morphogenetic proteins
Bone Morphogenetic Proteins
neurogenesis
Neurogenesis
cognition
133 Citations (Scopus)

Calcium-dependent afterhyperpolarization and learning in young and aging hippocampus

Disterhoft, J. F., Thompson, L. T., Moyer, J. R. & Mogul, D. J., Jul 3 1996, In : Life Sciences. 59, 5-6, p. 413-420 8 p.

Research output: Contribution to journalArticle

Hippocampus
Aging of materials
Learning
Calcium
Neurons
8 Citations (Scopus)

Caudate nucleus in retrieval of trace eyeblink conditioning after consolidation

Flores, L. C. & Disterhoft, J. F., Feb 13 2013, In : Journal of Neuroscience. 33, 7, p. 2828-2836 9 p.

Research output: Contribution to journalArticle

Caudate Nucleus
Rabbits
Neurons
Vibrissae
Conditioning (Psychology)
24 Citations (Scopus)

Caudate nucleus is critically involved in trace eyeblink conditioning

Flores, L. C. & Disterhoft, J. F., Nov 18 2009, In : Journal of Neuroscience. 29, 46, p. 14511-14520 10 p.

Research output: Contribution to journalArticle

Caudate Nucleus
Learning
Rabbits
Basal Ganglia
Neurons
3 Citations (Scopus)

Caution against using propylene glycol as a solvent in epilepsy drug research

Oh, M. M., Power, J. M., Thompson, L. T. & Disterhoft, J. F., Nov 20 2000, In : Neuroscience Research Communications. 27, 2, p. 117-124 8 p.

Research output: Contribution to journalArticle

Propylene Glycol
Epilepsy
Ethanol
Research
Pharmaceutical Preparations
20 Citations (Scopus)

Cerebellar cortical degeneration disrupts discrimination learning but not delay or trace classical eyeblink conditioning

Fortier, C. B., Disterhoft, J. F. & McGlinchey-Berroth, R., Jan 1 2000, In : Neuropsychology. 14, 4, p. 537-550 14 p.

Research output: Contribution to journalArticle

Discrimination Learning
Classical Conditioning
Cerebellar Nuclei
Cerebellar Cortex
Aptitude
32 Citations (Scopus)

Cholinergic facilitation of trace eyeblink conditioning in aging rabbits

Disterhoft, J. F., Kronforst-Collins, M., Oh, M. M., Power, J. M., Preston, A. R. & Weiss, C., Jan 8 1999, In : Life Sciences. 64, 6-7, p. 541-548 8 p.

Research output: Contribution to journalArticle

Trichlorfon
Cholinergic Agents
Neurons
Aging of materials
Learning
133 Citations (Scopus)

Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells

Coulter, D. A., Lo Turco, J. J., Kubota, M., Disterhoft, J. F., Moore, J. W. & Alkon, D. L., Jan 1 1989, In : Journal of neurophysiology. 61, 5, p. 971-981 11 p.

Research output: Contribution to journalArticle

Classical Conditioning
Pyramidal Cells
Rabbits
Calcium
Calcium Signaling
12 Citations (Scopus)

Cochlear nucleus unit responses to pure tones in the unanesthetized rabbit

Hui, G. S. & Disterhoft, J. F., Jan 1 1980, In : Experimental Neurology. 69, 3, p. 576-588 13 p.

Research output: Contribution to journalArticle

Cochlear Nucleus
Rabbits
Cats
Brain
3 Citations (Scopus)

Comments and Discussion

Disterhoft, J. F., Jan 1 1977, In : Physiological Psychology. 5, 4, p. 498-500 3 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Comparisons of dorsal and ventral hippocampus cornu ammonis region 1 pyramidal neuron activity during trace eye-blink conditioning in the rabbit

Weible, A. P., O'Reilly, J. A., Weiss, C. & Disterhoft, J. F., Aug 4 2006, In : Neuroscience. 141, 3, p. 1123-1137 15 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Hippocampus
Rabbits
Neurons
Conditioning (Psychology)
17 Citations (Scopus)

Conditional Discrimination Learning in Patients with Bilateral Medial Temporal Lobe Amnesia

Fortier, C. B., Disterhoft, J. F., Capozzi, S., Kilduff, P., Cronin-Golomb, A. & McGlinchey, R. E., Dec 1 2003, In : Behavioral Neuroscience. 117, 6, p. 1181-1195 15 p.

Research output: Contribution to journalArticle

Discrimination Learning
Amnesia
Temporal Lobe
Aptitude
Light

Conditioned Contextual Freezing is A Neurobehavioral Biomarker of Axonal Injury Indicated by Reduced Fractional Anisotropy in A Mouse Model of Blast-Induced Mild Traumatic Brain Injury

Weiss, C., Lendacki, F. R., Rigby, P. H., Wyrwicz, A. M., Disterhoft, J. F. & Spiess, J., Jan 1 2019, (Accepted/In press) In : Shock.

Research output: Contribution to journalArticle

Brain Concussion
Anisotropy
Freezing
Biomarkers
Fear