John F Disterhoft

  • 13759 Citations
1968 …2020

Research output per year

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Research Output

2010

Synaptic strength and postsynaptically silent synapses through advanced aging in rat hippocampal CA1 pyramidal neurons

Sametsky, E. A., Disterhoft, J. F., Geinisman, Y. & Nicholson, D. A., May 1 2010, In : Neurobiology of Aging. 31, 5, p. 813-825 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

The effects of aging in delay and trace human eyeblink conditioning

Cheng, D. T., Faulkner, M. L., Disterhoft, J. F. & Desmond, J. E., Sep 1 2010, In : Psychology and Aging. 25, 3, p. 684-690 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2009
20 Scopus citations

Autophosphorylation of αCaMKII downregulates excitability of CA1 pyramidal neurons following synaptic stimulation

Sametsky, E. A., Disterhoft, J. F. & Ohno, M., Jul 1 2009, In : Neurobiology of Learning and Memory. 92, 1, p. 120-123 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry

Bond, A. M., Vangompel, M. J. W., Sametsky, E. A., Clark, M. F., Savage, J. C., Disterhoft, J. F. & Kohtz, J. D., Aug 1 2009, In : Nature Neuroscience. 12, 8, p. 1020-1027 8 p.

Research output: Contribution to journalArticle

257 Scopus citations

Blocking the BK channel impedes acquisition of trace eyeblink conditioning

Matthews, E. A. & Disterhoft, J. F., Feb 1 2009, In : Learning and Memory. 16, 2, p. 106-109 4 p.

Research output: Contribution to journalArticle

30 Scopus citations

BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice

Gobeske, K. T., Das, S., Bonaguidi, M. A., Weiss, C., Radulovic, J., Disterhoft, J. F. & Kessler, J. A., Oct 20 2009, In : PloS one. 4, 10, e7506.

Research output: Contribution to journalArticle

68 Scopus citations

Caudate nucleus is critically involved in trace eyeblink conditioning

Flores, L. C. & Disterhoft, J. F., Nov 18 2009, In : Journal of Neuroscience. 29, 46, p. 14511-14520 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Intrinsic neuronal excitability is reversibly altered by a single experience in fear conditioning

McKay, B. M., Matthews, E. A., Oliveira, F. A. & Disterhoft, J. F., Nov 1 2009, In : Journal of neurophysiology. 102, 5, p. 2763-2770 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes

Cahill, M. E., Xie, Z., Day, M., Barbolina, M. V., Miller, C. A., Weiss, C., Radulovic, J., Sweatt, J. D., Disterhoft, J. F., Surmeier, D. J. & Penzes, P., Aug 4 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 31, p. 13058-13063 6 p.

Research output: Contribution to journalArticle

110 Scopus citations
51 Scopus citations

Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice

Kaczorowski, C. C. & Disterhoft, J. F., Jun 1 2009, In : Learning and Memory. 16, 6, p. 362-366 5 p.

Research output: Contribution to journalArticle

76 Scopus citations

The fast and slow after hyperpolarizations are differentially modulated in hippocampal neurons by aging and learning

Matthews, E. A., Linardakis, J. M. & Disterhoft, J. F., Apr 15 2009, In : Journal of Neuroscience. 29, 15, p. 4750-4755 6 p.

Research output: Contribution to journalArticle

66 Scopus citations
2008
36 Scopus citations

Delay Discrimination and Reversal Eyeblink Classical Conditioning in Abstinent Chronic Alcoholics

Fortier, C. B., Steffen, E. M., LaFleche, G., Venne, J. R., Disterhoft, J. F. & McGlinchey, R. E., Mar 1 2008, In : Neuropsychology. 22, 2, p. 196-208 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Enhanced neuronal excitability in rat CA1 pyramidal neurons following trace eyeblink conditioning acquisition is not due to alterations in IM

Kuo, A. G., Lee, G., McKay, B. M. & Disterhoft, J. F., Feb 1 2008, In : Neurobiology of Learning and Memory. 89, 2, p. 125-133 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
9 Scopus citations

Functional magnetic resonance imaging of delay and trace eyeblink conditioning in the primary visual cortex of the rabbit

Miller, M. J., Weiss, C., Song, X., Iordanescu, G., Disterhoft, J. F. & Wyrwicz, A. M., May 7 2008, In : Journal of Neuroscience. 28, 19, p. 4974-4981 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Neural substrates underlying human delay and trace eyeblink conditioning

Cheng, D. T., Disterhoft, J. F., Power, J. M., Ellis, D. A. & Desmond, J. E., Jun 10 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 23, p. 8108-8113 6 p.

Research output: Contribution to journalArticle

120 Scopus citations

Procedural Memory System Supports Single Cue Trace Eyeblink Conditioning in Medial Temporal Lobe Amnesia

McGlinchey, R. E., Capozzi, S. M., Fortier, C. B. & Disterhoft, J. F., Mar 1 2008, In : Neuropsychology. 22, 2, p. 278-282 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

The BK-mediated fAHP is modulated by learning a hippocampus-dependent task

Matthews, E. A., Weible, A. P., Shah, S. & Disterhoft, J. F., Sep 30 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 39, p. 15154-15159 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

Where is the trace in trace conditioning?

Woodruff-Pak, D. S. & Disterhoft, J. F., Feb 1 2008, In : Trends in Neurosciences. 31, 2, p. 105-112 8 p.

Research output: Contribution to journalReview article

139 Scopus citations
2007

Alterations in intrinsic neuronal excitability during normal aging

Disterhoft, J. F. & Oh, M. M., Jun 1 2007, In : Aging Cell. 6, 3, p. 327-336 10 p.

Research output: Contribution to journalReview article

93 Scopus citations

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

Ohno, M., Cole, S. L., Yasvoina, M., Zhao, J., Citron, M., Berry, R., Disterhoft, J. F. & Vassar, R., Apr 1 2007, In : Neurobiology of Disease. 26, 1, p. 134-145 12 p.

Research output: Contribution to journalArticle

205 Scopus citations
39 Scopus citations

Cortical barrel lesions impair whisker-CS trace eyeblink conditioning

Galvez, R., Weible, A. P. & Disterhoft, J. F., Jan 1 2007, In : Learning and Memory. 14, 1, p. 94-100 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Stability and plasticity of intrinsic membrane properties in hippocampal CA1 pyramidal neurons: Effects of internal anions

Kaczorowski, C. C., Disterhoft, J. & Spruston, N., Feb 1 2007, In : Journal of Physiology. 578, 3, p. 799-818 20 p.

Research output: Contribution to journalArticle

57 Scopus citations
2006

Comparisons of dorsal and ventral hippocampus cornu ammonis region 1 pyramidal neuron activity during trace eye-blink conditioning in the rabbit

Weible, A. P., O'Reilly, J. A., Weiss, C. & Disterhoft, J. F., Aug 4 2006, In : Neuroscience. 141, 3, p. 1123-1137 15 p.

Research output: Contribution to journalArticle

44 Scopus citations

Differential effects of αCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability

Ohno, M., Sametsky, E. A., Silva, A. J. & Disterhoft, J. F., Apr 1 2006, In : European Journal of Neuroscience. 23, 8, p. 2235-2240 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Galantamine increases excitability of CA1 hippocampal pyramidal neurons

Oh, M. M., Wu, W. W., Power, J. M. & Disterhoft, J. F., Jan 9 2006, In : Neuroscience. 137, 1, p. 113-123 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation

Oakley, H., Cole, S. L., Logan, S., Maus, E., Shao, P., Craft, J., Guillozet-Bongaarts, A., Ohno, M., Disterhoft, J., Van Eldik, L., Berry, R. & Vassar, R., Oct 4 2006, In : Journal of Neuroscience. 26, 40, p. 10129-10140 12 p.

Research output: Contribution to journalArticle

1241 Scopus citations

Learning, aging and intrinsic neuronal plasticity

Disterhoft, J. F. & Oh, M. M., Oct 1 2006, In : Trends in Neurosciences. 29, 10, p. 587-599 13 p.

Research output: Contribution to journalReview article

151 Scopus citations

Pharmacological and molecular enhancement of learning in aging and Alzheimer's disease

Disterhoft, J. F. & Oh, M. M., Mar 1 2006, In : Journal of Physiology Paris. 99, 2-3, p. 180-192 13 p.

Research output: Contribution to journalArticle

54 Scopus citations

Simultaneous training on two hippocampus-dependent tasks facilitates acquisition of trace eyeblink conditioning

Kuo, A. G., Lee, G. & Disterhoft, J. F., Mar 1 2006, In : Learning and Memory. 13, 2, p. 201-207 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Temporal memory deficits in Alzheimer's mouse models: Rescue by genetic deletion of BACE1

Ohno, M., Chang, L., Tseng, W., Oakley, H., Citron, M., Klein, W. L., Vassar, R. & Disterhoft, J. F., Jan 1 2006, In : European Journal of Neuroscience. 23, 1, p. 251-260 10 p.

Research output: Contribution to journalArticle

193 Scopus citations

Vibrissa-signaled eyeblink conditioning induces somatosensory cortical plasticity

Galvez, R., Weiss, C., Weible, A. P. & Disterhoft, J. F., Sep 8 2006, In : Journal of Neuroscience. 26, 22, p. 6062-6068 7 p.

Research output: Contribution to journalArticle

53 Scopus citations
2005

Acute stress facilitates trace eyeblink conditioning in C57BL/6 male mice and increases the excitability of their CA1 pyramidal neurons

Weiss, C., Sametsky, E., Sasse, A., Spiess, J. & Disterhoft, J. F., Mar 1 2005, In : Learning and Memory. 12, 2, p. 138-143 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

A fiber optic-based system for behavioral eyeblink measurement in a MRI environment

Miller, M. J., Li, L., Weiss, C., Disterhoft, J. F. & Wyrwicz, A. M., Jan 30 2005, In : Journal of Neuroscience Methods. 141, 1, p. 83-87 5 p.

Research output: Contribution to journalArticle

13 Scopus citations
58 Scopus citations

GLYX-13: A monoclonal antibody-derived peptide that acts as an N-methyl-D-aspartate receptor modulator

Moskal, J. R., Kuo, A. G., Weiss, C., Wood, P. L., O'Connor Hanson, A., Kelso, S., Harris, R. B. & Disterhoft, J. F., Dec 1 2005, In : Neuropharmacology. 49, 7, p. 1077-1087 11 p.

Research output: Contribution to journalArticle

68 Scopus citations

Trace eyeblink conditioning in abstinent alcoholic individuals: Effects of complex task demands and prior conditioning

McGlinchey, R. E., Capozzi, S. M., Fortier, C. B. & Disterhoft, J. F., Mar 1 2005, In : Neuropsychology. 19, 2, p. 159-170 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Trace eyeblink conditioning requires the hippocampus but not autophosphorylation of αCaMKII in mice

Ohno, M., Tseng, W., Silva, A. J. & Disterhoft, J. F., May 1 2005, In : Learning and Memory. 12, 3, p. 211-215 5 p.

Research output: Contribution to journalArticle

21 Scopus citations
2004

Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum

Geinisman, Y., Ganeshina, O., Yoshida, R., Berry, R. W., Disterhoft, J. F. & Gallagher, M., Mar 2004, In : Neurobiology of Aging. 25, 3, p. 407-416 10 p.

Research output: Contribution to journalArticle

126 Scopus citations

Aging-related alterations in the distribution of Ca2+-dependent PKC isoforms in rabbit hippocampus

Van de Zee, E. A., Palm, I. F., O'Connor, M., Maizels, E. T., Hunzicker-Dunn, M. & Disterhoft, J. F., Nov 29 2004, In : Hippocampus. 14, 7, p. 849-860 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

BACE1 Deficiency Rescues Memory Deficits and Cholinergic Dysfunction in a Mouse Model of Alzheimer's Disease

Ohno, M., Sametsky, E. A., Younkin, L. H., Oakley, H., Younkin, S. G., Citron, M., Vassar, R. & Disterhoft, J. F., Jan 8 2004, In : Neuron. 41, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

428 Scopus citations

Biophysical alterations of hippocampal pyramidal neurons in learning, ageing and Alzheimer's disease

Disterhoft, J. F., Wu, W. W. & Ohno, M., Nov 2004, In : Ageing Research Reviews. 3, 4, p. 383-406 24 p.

Research output: Contribution to journalShort survey

69 Scopus citations

Cognitive Neuroscience

Weiss, C. & Disterhoft, J. F., Jan 1 2004, Encyclopedia of Social Measurement. Elsevier Inc, p. 341-349 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Galantamine Facilitates Acquisition of Hippocampus-Dependent Trace Eyeblink Conditioning in Aged Rabbits

Weible, A. P., Oh, M. M., Lee, G. & Disterhoft, J. F., Jan 1 2004, In : Learning and Memory. 11, 1, p. 108-115 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
48 Scopus citations