John F Disterhoft

  • 13038 Citations
1968 …2024
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1968 2019

Filter
Article
2019

Conditioned Contextual Freezing is A Neurobehavioral Biomarker of Axonal Injury Indicated by Reduced Fractional Anisotropy in A Mouse Model of Blast-Induced Mild Traumatic Brain Injury

Weiss, C., Lendacki, F. R., Rigby, P. H., Wyrwicz, A. M., Disterhoft, J. F. & Spiess, J., Jan 1 2019, (Accepted/In press) In : Shock.

Research output: Contribution to journalArticle

Brain Concussion
Anisotropy
Freezing
Biomarkers
Fear
Entorhinal Cortex
Dentate Gyrus
Learning
Neurons
Temporal Lobe

How do we validate approaches that aim to harness reserve to improve the aging brain?

White, L. R., Boyle, P. A., Foster, T. C., Gazzaley, A. H. & Disterhoft, J. F., Jan 1 2019, In : Neurobiology of Aging.

Research output: Contribution to journalArticle

Brain
Cognitive Reserve
Molecular Biology
Pathology
Health
2018
3 Citations (Scopus)

Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease

Musial, T. F., Molina-Campos, E., Bean, L. A., Ybarra, N., Borenstein, R., Russo, M. L., Buss, E. W., Justus, D., Neuman, K. M., Ayala, G. D., Mullen, S. A., Voskobiynyk, Y., Tulisiak, C. T., Fels, J. A., Corbett, N. J., Carballo, G., Kennedy, C. D., Popovic, J., Ramos-Franco, J., Fill, M. & 13 others, Pergande, M. R., Borgia, J. A., Corbett, G. T., Pahan, K., Han, Y., Chetkovich, D. M., Vassar, R. J., Byrne, R. W., Matthew Oh, M., Stoub, T. R., Remy, S., Disterhoft, J. F. & Nicholson, D. A., Oct 1 2018, In : Neurobiology of Learning and Memory. 154, p. 141-157 17 p.

Research output: Contribution to journalArticle

Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Channelopathies
Alzheimer Disease
Cyclic Nucleotides
Nervous System Diseases
1 Citation (Scopus)

The rabbit as a behavioral model system for magnetic resonance imaging

Weiss, C., Procissi, D., Power, J. M. & Disterhoft, J. F., Apr 15 2018, In : Journal of Neuroscience Methods. 300, p. 196-205 10 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Rabbits
Brain
Head
Vibrissae
2017
14 Citations (Scopus)

CREB, cellular excitability, and cognition: Implications for aging

Yu, X. W., Oh, M. M. & Disterhoft, J. F., Mar 30 2017, In : Behavioural Brain Research. 322, p. 206-211 6 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Cognition
Laboratory Animals
Young Adult
Transcription Factors
10 Citations (Scopus)

CREB overexpression in dorsal CA1 ameliorates long-term memory deficits in aged rats

Yu, X. W., Curlik, D. M., Oh, M. M., Yin, J. C. P. & Disterhoft, J. F., Jan 4 2017, In : eLife. 6, e19358.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Long-Term Memory
Memory Disorders
Rats
Data storage equipment
2016
4 Citations (Scopus)
Manganese
Magnetic Resonance Imaging
Rabbits
Vibrissae
Somatosensory Cortex
12 Citations (Scopus)

Intrinsic connectivity of neural networks in the awake rabbit

Schroeder, M. P., Weiss, C., Procissi, D., Disterhoft, J. F. & Wang, L., Apr 1 2016, In : Neuroimage. 129, p. 260-267 8 p.

Research output: Contribution to journalArticle

Rabbits
Brain
Animal Models
Parietal Lobe
Somatosensory Cortex
3 Citations (Scopus)
Somatosensory Cortex
Vibrissae
Rabbits
Hippocampus
Cerebellar Nuclei
1 Citation (Scopus)

Whisker-signaled eyeblink classical conditioning in head-fixed mice

Lin, C., Disterhoft, J. F. & Weiss, C., Mar 30 2016, In : Journal of Visualized Experiments. 2016, 109, e53310.

Research output: Contribution to journalArticle

Vibrissae
Classical Conditioning
Head
Data storage equipment
Learning
2015
36 Citations (Scopus)

Aging-related hyperexcitability in CA3 pyramidal neurons is mediated by enhanced A-type K+ channel function and expression

Simkin, D., Hattori, S., Ybarra, N., Musia, T. F., Buss, E. W., Richter, H., Oh, M. M., Nicholson, D. A. & Disterhoft, J. F., Sep 23 2015, In : Journal of Neuroscience. 35, 38, p. 13206-13218 13 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Action Potentials
Cognition
Hippocampus
Western Blotting

Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression

Simkin, D., Hattori, S., Ybarra, N., Musial, T. F., Buss, E. W., Richter, H., Oh, M. M., Nicholson, D. A. & Disterhoft, J. F., Sep 23 2015, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 38, p. 13206-13218 13 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Action Potentials
Neurons
Cognition
Hippocampus
2 Citations (Scopus)

Hippocampectomy disrupts trace eye-blink conditioning in rabbits

Moyer, J. R., Deyo, R. A. & Disterhoft, J. F., Jan 1 2015, In : Behavioral Neuroscience. 129, 4, p. 523-532 10 p.

Research output: Contribution to journalArticle

Rabbits
Reaction Time
Hippocampus
Air
Learning
35 Citations (Scopus)
Post-Traumatic Stress Disorders
Prefrontal Cortex
N-Methyl-D-Aspartate Receptors
Fear
Depression
20 Citations (Scopus)

Robust hippocampal responsivity during retrieval of consolidated associative memory

Hattori, S., Chen, L., Weiss, C. & Disterhoft, J. F., May 1 2015, In : Hippocampus. 25, 5, p. 655-669 15 p.

Research output: Contribution to journalArticle

Hippocampus
Long-Term Memory
Rabbits
Neocortex
Animal Models
11 Citations (Scopus)
Prosencephalon
Neurosciences
Hippocampus
Rabbits
Neurons
39 Citations (Scopus)

The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus

Burgdorf, J., Zhang, X. L., Weiss, C., Gross, A., Boikess, S. R., Kroes, R. A., Khan, M. A., Burch, R. M., Rex, C. S., Disterhoft, J. F., Stanton, P. K. & Moskal, J. R., Nov 12 2015, In : Neuroscience. 308, p. 202-211 10 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
Long-Term Potentiation
Antidepressive Agents
Hippocampus
Dendritic Spines
2014
6 Citations (Scopus)

Age-related impairments on one hippocampal-dependent task predict impairments on a subsequent hippocampal-dependent task

Curlik, D. M., Weiss, C., Nicholson, D. A. & Disterhoft, J. F., Jan 1 2014, In : Behavioral Neuroscience. 128, 6, p. 676-688 13 p.

Research output: Contribution to journalArticle

Learning
Water
Aptitude
Hippocampus
Conditioning (Psychology)
28 Citations (Scopus)

Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2

Gorrie, G. H., Fecto, F., Radzicki, D., Weiss, C., Shi, Y., Dong, H., Zhai, H., Fu, R., Liu, E., Li, S., Arrat, H., Bigio, E. H., Disterhoft, J. F., Martina, M., Mugnaini, E., Siddique, T., Deng, H. X. & Russell, D. W., Oct 7 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 40, p. 14524-14529 6 p.

Research output: Contribution to journalArticle

Dendritic Spines
Amyotrophic Lateral Sclerosis
Transgenic Mice
Dementia
Ubiquitinated Proteins
24 Citations (Scopus)

Functional MRI of cerebellar activity during eyeblink classical conditioning in children and adults

Cheng, D. T., Meintjes, E. M., Stanton, M. E., Desmond, J. E., Pienaar, M., Dodge, N. C., Power, J. M., Molteno, C. D., Disterhoft, J. F., Jacobson, J. L. & Jacobson, S. W., Jan 1 2014, In : Human Brain Mapping. 35, 4, p. 1390-1403 14 p.

Research output: Contribution to journalArticle

Classical Conditioning
Cerebellar Nuclei
Magnetic Resonance Imaging
Brain
Cerebellar Cortex
37 Citations (Scopus)

Functional reorganization of a prefrontal cortical network mediating consolidation of trace eyeblink conditioning

Hattori, S., Yoon, T., Disterhoft, J. F. & Weiss, C., Jan 27 2014, In : Journal of Neuroscience. 34, 4, p. 1432-1445 14 p.

Research output: Contribution to journalArticle

Neurons
Long-Term Memory
Rabbits
Prefrontal Cortex
Vibrissae
20 Citations (Scopus)

Surface L-type Ca2+ channel expression levels are increased in aged hippocampus

Núñez-Santana, F. L., Oh, M. M., Antion, M. D., Lee, A., Hell, J. W. & Disterhoft, J. F., Feb 1 2014, In : Aging Cell. 13, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Hippocampus
Cell Membrane
Biotinylation
Hippocampal CA3 Region
2013
36 Citations (Scopus)

Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons

Oh, M. M., Oliveira, F. A., Waters, J. & Disterhoft, J. F., May 10 2013, In : Journal of Neuroscience. 33, 18, p. 7905-7911 7 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Calcium
Neurons
Age Factors
Photons
8 Citations (Scopus)

Caudate nucleus in retrieval of trace eyeblink conditioning after consolidation

Flores, L. C. & Disterhoft, J. F., Feb 13 2013, In : Journal of Neuroscience. 33, 7, p. 2828-2836 9 p.

Research output: Contribution to journalArticle

Caudate Nucleus
Rabbits
Neurons
Vibrissae
Conditioning (Psychology)
32 Citations (Scopus)

Learning increases intrinsic excitability of hippocampal interneurons

Mckay, B. M., Oh, M. M. & Disterhoft, J. F., Mar 27 2013, In : Journal of Neuroscience. 33, 13, p. 5499-5506 8 p.

Research output: Contribution to journalArticle

Interneurons
Learning
Pyramidal Cells
Somatostatin
Hippocampus
15 Citations (Scopus)
Entorhinal Cortex
Hippocampus
2012
7 Citations (Scopus)

A MRI-compatible system for whisker stimulation

Li, L., Weiss, C., Talk, A. C., Disterhoft, J. F. & Wyrwicz, A. M., Apr 15 2012, In : Journal of Neuroscience Methods. 205, 2, p. 305-311 7 p.

Research output: Contribution to journalArticle

Vibrissae
Magnetic Resonance Imaging
Vibration
Magnets
Head
25 Citations (Scopus)

Increasing SK2 channel activity impairs associative learning

McKay, B. M., Matthew Oh, M., Galvez, R., Burgdorf, J., Kroes, R. A., Weiss, C., Adelman, J. P., Moskal, J. R. & Disterhoft, J. F., Aug 1 2012, In : Journal of Neurophysiology. 108, 3, p. 863-870 8 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Hippocampus
Learning
Small-Conductance Calcium-Activated Potassium Channels
Biomarkers
11 Citations (Scopus)

Infragranular barrel cortex activity is enhanced with learning

Ward, R. L., Flores, L. C. & Disterhoft, J. F., Sep 1 2012, In : Journal of Neurophysiology. 108, 5, p. 1278-1287 10 p.

Research output: Contribution to journalArticle

Learning
Vibrissae
Neurons
Rabbits
Research
2011
16 Citations (Scopus)

Age-related deficits in a forebrain-dependent task, trace-eyeblink conditioning

Galvez, R., Cua, S. & Disterhoft, J. F., Oct 1 2011, In : Neurobiology of Aging. 32, 10, p. 1915-1922 8 p.

Research output: Contribution to journalArticle

Vibrissae
Prosencephalon
Aptitude
Neocortex
Learning
68 Citations (Scopus)

Exploring prefrontal cortical memory mechanisms with eyeblink conditioning

Weiss, C. & Disterhoft, J. F., Jun 1 2011, In : Behavioral Neuroscience. 125, 3, p. 318-326 9 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
Cerebellum
Hippocampus
Cerebellar Nuclei
Pyramidal Cells
47 Citations (Scopus)

Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease

Kaczorowski, C. C., Sametsky, E., Shah, S., Vassar, R. & Disterhoft, J. F., Aug 1 2011, In : Neurobiology of Aging. 32, 8, p. 1452-1465 14 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Learning
Fear
Neurons
Patch-Clamp Techniques
3 Citations (Scopus)

Physiological and anatomical studies of associative learning: Convergence with learning studies of W.T. Greenough

Galvez, R., Nicholson, D. A. & Disterhoft, J. F., Jul 1 2011, In : Developmental Psychobiology. 53, 5, p. 489-504 16 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Learning
Information Storage and Retrieval
Brain
Memory Consolidation
39 Citations (Scopus)

Positive emotional learning is regulated in the medial prefrontal cortex by GluN2B-containing NMDA receptors

Burgdorf, J., Kroes, R. A., Weiss, C., Oh, M. M., Disterhoft, J. F., Brudzynski, S. M., Panksepp, J. & Moskal, J. R., Sep 29 2011, In : Neuroscience. 192, p. 515-523 9 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
N-Methyl-D-Aspartate Receptors
Learning
Pleasure
Ultrasonics
17 Citations (Scopus)

Reevaluating Hippocampus-Dependent Learning in FVB/N Mice

Farley, S. J., McKay, B. M., Disterhoft, J. F. & Weiss, C., Dec 1 2011, In : Behavioral Neuroscience. 125, 6, p. 871-878 8 p.

Research output: Contribution to journalArticle

Hippocampus
Learning
Vision Disorders
Transgenic Mice
Fear
62 Citations (Scopus)

The N-methyl-d-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats

Burgdorf, J., Zhang, X. L., Weiss, C., Matthews, E., Disterhoft, J. F., Stanton, P. K. & Moskal, J. R., Apr 1 2011, In : Neurobiology of Aging. 32, 4, p. 698-706 9 p.

Research output: Contribution to journalArticle

Young Adult
Learning
Long-Term Potentiation
N-Methyl-D-Aspartate Receptors
Water
2010
24 Citations (Scopus)

Synaptic strength and postsynaptically silent synapses through advanced aging in rat hippocampal CA1 pyramidal neurons

Sametsky, E. A., Disterhoft, J. F., Geinisman, Y. & Nicholson, D. A., May 1 2010, In : Neurobiology of Aging. 31, 5, p. 813-825 13 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Synapses
Membrane Potentials
Hippocampal CA1 Region
Neurotransmitter Receptor
15 Citations (Scopus)

The effects of aging in delay and trace human eyeblink conditioning

Cheng, D. T., Faulkner, M. L., Disterhoft, J. F. & Desmond, J. E., Sep 1 2010, In : Psychology and Aging. 25, 3, p. 684-690 7 p.

Research output: Contribution to journalArticle

Young Adult
Aptitude
Classical Conditioning
Conditioning (Psychology)
2009
18 Citations (Scopus)
Vibrissae
Neuronal Plasticity
Prosencephalon
Rodentia
Shock
10 Citations (Scopus)

Autophosphorylation of αCaMKII downregulates excitability of CA1 pyramidal neurons following synaptic stimulation

Sametsky, E. A., Disterhoft, J. F. & Ohno, M., Jul 1 2009, In : Neurobiology of Learning and Memory. 92, 1, p. 120-123 4 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Pyramidal Cells
Down-Regulation
Learning
Neurons
238 Citations (Scopus)

Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry

Bond, A. M., Vangompel, M. J. W., Sametsky, E. A., Clark, M. F., Savage, J. C., Disterhoft, J. F. & Kohtz, J., Aug 1 2009, In : Nature Neuroscience. 12, 8, p. 1020-1027 8 p.

Research output: Contribution to journalArticle

Untranslated RNA
Interneurons
Prosencephalon
gamma-Aminobutyric Acid
Hippocampus
30 Citations (Scopus)

Blocking the BK channel impedes acquisition of trace eyeblink conditioning

Matthews, E. A. & Disterhoft, J. F., Feb 1 2009, In : Learning and Memory. 16, 2, p. 106-109 4 p.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Learning
Action Potentials
Hippocampus
Conditioning (Psychology)
63 Citations (Scopus)

BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice

Gobeske, K. T., Das, S., Bonaguidi, M. A., Weiss, C., Radulovic, J., Disterhoft, J. F. & Kessler, J., Oct 20 2009, In : PloS one. 4, 10, e7506.

Research output: Contribution to journalArticle

bone morphogenetic proteins
Bone Morphogenetic Proteins
neurogenesis
Neurogenesis
cognition
24 Citations (Scopus)

Caudate nucleus is critically involved in trace eyeblink conditioning

Flores, L. C. & Disterhoft, J. F., Nov 18 2009, In : Journal of Neuroscience. 29, 46, p. 14511-14520 10 p.

Research output: Contribution to journalArticle

Caudate Nucleus
Learning
Rabbits
Basal Ganglia
Neurons
47 Citations (Scopus)

Intrinsic neuronal excitability is reversibly altered by a single experience in fear conditioning

McKay, B. M., Matthews, E. A., Oliveira, F. A. & Disterhoft, J. F., Nov 1 2009, In : Journal of neurophysiology. 102, 5, p. 2763-2770 8 p.

Research output: Contribution to journalArticle

Fear
Learning
Patch-Clamp Techniques
Cues
Conditioning (Psychology)
107 Citations (Scopus)

Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes

Cahill, M. E., Xie, Z., Day, M., Barbolina, M. V., Miller, C. A., Weiss, C., Radulovic, J., Sweatt, J. D., Disterhoft, J. F., Surmeier Jr, D. J. & Penzes, P., Aug 4 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 31, p. 13058-13063 6 p.

Research output: Contribution to journalArticle

Morphogenesis
Spine
Phenotype
Guanine Nucleotide Exchange Factors
Dendritic Spines
49 Citations (Scopus)
Pyramidal Cells
Cyclic AMP-Dependent Protein Kinases
Learning
Protein Kinase C
Baths
68 Citations (Scopus)

Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice

Kaczorowski, C. C. & Disterhoft, J. F., Jun 1 2009, In : Learning and Memory. 16, 6, p. 362-366 5 p.

Research output: Contribution to journalArticle

Aptitude
Memory Disorders
Fear
Learning
Neuronal Plasticity
62 Citations (Scopus)

The fast and slow after hyperpolarizations are differentially modulated in hippocampal neurons by aging and learning

Matthews, E. A., Linardakis, J. M. & Disterhoft, J. F., Apr 15 2009, In : Journal of Neuroscience. 29, 15, p. 4750-4755 6 p.

Research output: Contribution to journalArticle

Learning
Neurons
Action Potentials
Synapses
Potassium