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Personal profile

Research Interests

Dr. Csernansky serves as the Lizzie Gilman Professor and Chair in the Department of Psychiatry and Behavioral Sciences at Northwestern University Feinberg School of Medicine. His research interests include in vivo neuroimaging of neuropsychiatric disorders, especially schizophrenia and Alzheimer disease, clinical trials of cognition-enhancing drugs, and the development of valid animal models for neuropsychiatric disorders. Dr. Csernansky has over 250 peer-reviewed publications, and has also authored several chapters and books, and his research program has received grant support from the National Institute of Mental Health, the National Institute of Aging, and the Department of Veterans Affairs, as well as several foundations and pharmaceutical companies. He is a Distinguished Fellow of the American Psychiatric Association and a member and officer of the American College of Neuropsychopharmacology and the Society of Biological Psychiatry. He has served as an Associate Editor of Schizophrenia Bulletin and on the Editorial Board of Schizophrenia Research and Neuropsychopharmacology.

Certifications and Licenses


Training Experience

1980Internship, Stanford University Medical Center
1983Residency, Stanford University School of Medicine

Education/Academic qualification

MD, New York University

… → 1979


  • Clinical Trial Methodology
  • Cognitive Neuroscience
  • Dementia
  • Interdisciplinary Research
  • Neuroscience
  • Psychiatry
  • Quantitative MRI
  • Schizophrenia

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Grants 2008 2023

Behavioral Symptoms
Alzheimer Disease
Multimodal Imaging
Frontotemporal Dementia
Alzheimer Disease
Differential Diagnosis
Sex Characteristics
Alzheimer Disease
Corticotropin-Releasing Hormone
Transgenic Mice
Histone Code
Antipsychotic Agents
Histone Deacetylase Inhibitors
Drug-Related Side Effects and Adverse Reactions

Research Output 1975 2018

Characterization of CNTNAP2 nanostructures on interneuronal dendrites

Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier Jr, D. J. & Penzes, P., Sep 1 2018, In : Molecular Psychiatry. 23, 9, 1 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

CNTNAP2 stabilizes interneuron dendritic arbors through CASK

Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier Jr, D. J. & Penzes, P., Sep 1 2018, In : Molecular Psychiatry. 23, 9, p. 1832-1850 19 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Protein-Serine-Threonine Kinases
Knockout Mice
2 Citations (Scopus)

Corticotrophin releasing factor receptor 1 antagonists prevent chronic stress-induced behavioral changes and synapse loss in aged rats

Dong, H., Keegan, J. M., Hong, E., Gallardo, C., Montalvo-Ortiz, J., Wang, B., Rice, K. C. & Csernansky, J. G., Apr 1 2018, In : Psychoneuroendocrinology. 90, p. 92-101 10 p.

Research output: Contribution to journalArticle

R 121919
Memory Disorders
Dendritic Spines

Differential neurotoxicity related to tetracycline transactivator and TDP-43 expression in conditional TDP-43 mouse model of frontotemporal lobar degeneration

Kukreja, L., Shahidehpour, R., Kim, G., Keegan, J., Sadleir, K. R., Russell, T., Csernansky, J. G., Mesulam, M-M., Vassar, R. J., Wang, L., Dong, H. & Geula, C., Jul 4 2018, In : Journal of Neuroscience. 38, 27, p. 6045-6062 18 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
DNA-Binding Proteins

Medication-assisted treatment for alcohol use disorder: Hope for incarcerated patients and for our communities

Aaronson, A., Adelstein, J. & Csernansky, J. G., Jul 1 2018, In : American Journal of Psychiatry. 175, 7, p. 596-597 2 p.

Research output: Contribution to journalReview article