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Personal profile

Research Interests

Dr. Csernansky serves as the Lizzie Gilman Professor and Chair in the Department of Psychiatry and Behavioral Sciences at Northwestern University Feinberg School of Medicine. His research interests include in vivo neuroimaging of neuropsychiatric disorders, especially schizophrenia and Alzheimer disease, clinical trials of cognition-enhancing drugs, and the development of valid animal models for neuropsychiatric disorders. Dr. Csernansky has over 250 peer-reviewed publications, and has also authored several chapters and books, and his research program has received grant support from the National Institute of Mental Health, the National Institute of Aging, and the Department of Veterans Affairs, as well as several foundations and pharmaceutical companies. He is a Distinguished Fellow of the American Psychiatric Association and a member and officer of the American College of Neuropsychopharmacology and the Society of Biological Psychiatry. He has served as an Associate Editor of Schizophrenia Bulletin and on the Editorial Board of Schizophrenia Research and Neuropsychopharmacology.

Certifications and Licenses

Psychiatry

Training Experience

1980Internship, Stanford University Medical Center
1983Residency, Stanford University School of Medicine

Education/Academic qualification

MD, New York University

… → 1979

Keywords

  • Clinical Trial Methodology
  • Cognitive Neuroscience
  • Dementia
  • Interdisciplinary Research
  • Neuroscience
  • Psychiatry
  • Quantitative MRI
  • Schizophrenia

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Grants 2008 2024

Behavioral Symptoms
Dementia
Alzheimer Disease
Psychology
Apathy
Sex Characteristics
Alzheimer Disease
Corticotropin-Releasing Hormone
Transgenic Mice
Phosphorylation
Multimodal Imaging
Frontotemporal Dementia
Alzheimer Disease
Differential Diagnosis
Biomarkers

Research Output 1975 2019

Editorial: Stress and its impact on Alzheimer's Disease

Dong, H. & Csernansky, J. G., Feb 1 2019, In : Neurobiology of Stress. 10, 100167.

Research output: Contribution to journalEditorial

Open Access
Alzheimer Disease

Characterization of CNTNAP2 nanostructures on interneuronal dendrites

Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier Jr, D. J. & Penzes, P., Sep 1 2018, In : Molecular Psychiatry. 23, 9, 1 p.

Research output: Contribution to journalArticle

Nanostructures
Dendrites
3 Citations (Scopus)

CNTNAP2 stabilizes interneuron dendritic arbors through CASK

Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier Jr, D. J. & Penzes, P., Sep 1 2018, In : Molecular Psychiatry. 23, 9, p. 1832-1850 19 p.

Research output: Contribution to journalArticle

Contactins
Calcium-Calmodulin-Dependent Protein Kinases
Protein-Serine-Threonine Kinases
Interneurons
Knockout Mice
2 Citations (Scopus)

Corticotrophin releasing factor receptor 1 antagonists prevent chronic stress-induced behavioral changes and synapse loss in aged rats

Dong, H., Keegan, J. M., Hong, E., Gallardo, C., Montalvo-Ortiz, J., Wang, B., Rice, K. C. & Csernansky, J. G., Apr 1 2018, In : Psychoneuroendocrinology. 90, p. 92-101 10 p.

Research output: Contribution to journalArticle

R 121919
Memory Disorders
Synapses
Anxiety
Dendritic Spines

Differential neurotoxicity related to tetracycline transactivator and TDP-43 expression in conditional TDP-43 mouse model of frontotemporal lobar degeneration

Kukreja, L., Shahidehpour, R., Kim, G., Keegan, J., Sadleir, K. R., Russell, T., Csernansky, J. G., Mesulam, M-M., Vassar, R. J., Wang, L., Dong, H. & Geula, C., Jul 4 2018, In : Journal of Neuroscience. 38, 27, p. 6045-6062 18 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Trans-Activators
DNA-Binding Proteins
Tetracycline
Atrophy