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2020

Brain morphometric differences in youth with and without perinatally-acquired HIV: A cross-sectional study

for the Pediatric HIV/AIDS Cohort Study (PHACS) and the Pediatric Imaging, Neurocognition, and Genetics (PING) Study, 2020, In : NeuroImage: Clinical. 26, 102246.

Research output: Contribution to journalArticle

Open Access

The characteristics of cognitive neuroscience tests in a schizophrenia cognition clinical trial: Psychometric properties and correlations with standard measures

Kraus, M. S., Gold, J. M., Barch, D. M., Walker, T. M., Chun, C. A., Buchanan, R. W., Csernansky, J. G., Goff, D. C., Green, M. F., Jarskog, L. F., Javitt, D. C., Kimhy, D., Lieberman, J. A., McEvoy, J. P., Mesholam-Gately, R. I., Seidman, L. J., Ball, M. P., Kern, R. S., McMahon, R. P., Robinson, J. & 2 others, Marder, S. R. & Keefe, R. S. E., Mar 2020, In : Schizophrenia Research: Cognition. 19, 100161.

Research output: Contribution to journalArticle

Open Access
2019

Improving the evaluation of adult mental disorders in the criminal justice system with computerized adaptive testing

Gibbons, R. D., Smith, J. D., Brown, C. H., Sajdak, M., Tapia, N. J., Kulik, A., Epperson, M. W. & Csernansky, J., Jan 1 2019, In : Psychiatric Services. 70, 11, p. 1040-1043 4 p.

Research output: Contribution to journalArticle

Open Access

Monthly Extended-Release Risperidone (RBP-7000) in the Treatment of Schizophrenia: Results from the Phase 3 Program

Andorn, A., Graham, J., Csernansky, J., Newcomer, J. W., Shinde, S., Muma, G., Heidbreder, C. & Fava, M., Sep 1 2019, In : Journal of clinical psychopharmacology. 39, 5, p. 428-433 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Characterization of CNTNAP2 nanostructures on interneuronal dendrites

Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier, D. J. & Penzes, P., Sep 1 2018, In : Molecular Psychiatry. 23, 9, 1 p.

Research output: Contribution to journalArticle

CNTNAP2 stabilizes interneuron dendritic arbors through CASK

Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier, D. J. & Penzes, P., Sep 1 2018, In : Molecular Psychiatry. 23, 9, p. 1832-1850 19 p.

Research output: Contribution to journalArticle

9 Scopus citations

Corticotrophin releasing factor receptor 1 antagonists prevent chronic stress-induced behavioral changes and synapse loss in aged rats

Dong, H., Keegan, J. M., Hong, E., Gallardo, C., Montalvo-Ortiz, J., Wang, B., Rice, K. C. & Csernansky, J., Apr 2018, In : Psychoneuroendocrinology. 90, p. 92-101 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Differential neurotoxicity related to tetracycline transactivator and TDP-43 expression in conditional TDP-43 mouse model of frontotemporal lobar degeneration

Kukreja, L., Shahidehpour, R., Kim, G., Keegan, J., Sadleir, K. R., Russell, T., Csernansky, J., Mesulam, M., Vassar, R. J., Wang, L., Dong, H. & Geula, C., Jul 4 2018, In : Journal of Neuroscience. 38, 27, p. 6045-6062 18 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Basal forebrain mediated increase in brain CRF is associated with increased cholinergic tone and depression

Gollan, J. K., Dong, H., Bruno, D., Nierenberg, J., Nobrega, J. N., Grothe, M. J., Pollock, B. G., Marmar, C. R., Teipel, S., Csernansky, J. G. & Pomara, N., Jun 30 2017, In : Psychiatry Research - Neuroimaging. 264, p. 76-81 6 p.

Research output: Contribution to journalArticle

Cortical thickness of neural substrates supporting cognitive empathy in individuals with schizophrenia

Massey, S. H., Stern, D., Alden, E. C., Petersen, J. E., Cobia, D. J., Wang, L., Csernansky, J. G. & Smith, M., Jan 1 2017, In : Schizophrenia Research. 179, p. 119-124 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer's disease-related signaling

Bangasser, D. A., Dong, H., Carroll, J., Plona, Z., Ding, H., Rodriguez, L., McKennan, C., Csernansky, J. G., Seeholzer, S. H. & Valentino, R. J., Aug 1 2017, In : Molecular Psychiatry. 22, 8, p. 1126-1133 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Default mode functional connectivity is associated with social functioning in schizophrenia

Fox, J. M., Abram, S. V., Reilly, J. L., Eack, S., Goldman, M. B., Csernansky, J. G., Wang, L. & Smith, M. J., May 2017, In : Journal of abnormal psychology. 126, 4, p. 392-405 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Fronto-temporal connectivity predicts cognitive empathy deficits and experiential negative symptoms in schizophrenia

Abram, S. V., Wisner, K. M., Fox, J. M., Barch, D. M., Wang, L., Csernansky, J. G., MacDonald, A. W. & Smith, M. J., Mar 1 2017, In : Human Brain Mapping. 38, 3, p. 1111-1124 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice

Montalvo-Ortiz, J. L., Fisher, D. W., Rodríguez, G., Fang, D., Csernansky, J. G. & Dong, H., Aug 1 2017, In : Psychopharmacology. 234, 16, p. 2385-2398 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

Keypress-based musical preference is both individual and lawful

Livengood, S. L., Sheppard, J. P., Kim, B. W., Malthouse, E. C., Bourne, J. E., Barlow, A. E., Lee, M. J., Marin, V., O'Connor, K. P., Csernansky, J. G., Block, M. P., Blood, A. J. & Breiter, H. C., Jan 1 2017, In : Frontiers in Neuroscience. 11, MAY, 136.

Research output: Contribution to journalArticle

2 Scopus citations

Lower total and regional grey matter brain volumes in youth with perinatally-acquired HIV infection: Associations with HIV disease severity, substance use, and cognition

Pediatric HIV/AIDS Cohort Study (PHACS) and the Pediatric Imaging, Neurocognition, and Genetics (PING) Study, May 1 2017, In : Brain, Behavior, and Immunity. 62, p. 100-109 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Neural correlates of preserved facial affect perception in high functioning schizophrenia

Karpouzian, T. M., Schroeder, M. P., Abram, S. V., Wanar, H., Alden, E. C., Eack, S. M., Csernansky, J. G. & Smith, M. J., Aug 30 2017, In : Psychiatry Research - Neuroimaging. 266, p. 83-85 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Progressive deterioration of thalamic nuclei relates to cortical network decline in schizophrenia

Cobia, D. J., Smith, M., Salinas, I., Ng, C., Gado, M., Csernansky, J. G. & Wang, L., Feb 1 2017, In : Schizophrenia Research. 180, p. 21-27 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
4 Scopus citations
2016

Deformed Subcortical Structures Are Related to Past HIV Disease Severity in Youth With Perinatally Acquired HIV Infection

for the Pediatric HIV/AIDS Cohort Study (PHACS), Jan 1 2016, In : Journal of the Pediatric Infectious Diseases Society. 5, p. S6-S14

Research output: Contribution to journalArticle

16 Scopus citations

Report on ISCTM Consensus Meeting on Clinical Assessment of Response to Treatment of Cognitive Impairment in Schizophrenia

Keefe, R. S. E., Haig, G. M., Marder, S. R., Harvey, P. D., Dunayevich, E., Medalia, A., Davidson, M., Lombardo, I., Bowie, C. R., Buchanan, R. W., Bugarski-Kirola, D., Carpenter, W. T., Csernansky, J. T., Dago, P. L., Durand, D. M., Frese, F. J., Goff, D. C., Gold, J. M., Hooker, C. I., Kopelowicz, A. & 5 others, Loebel, A., McGurk, S. R., Opler, L. A., Pinkham, A. E. & Stern, R. G., Jan 1 2016, In : Schizophrenia bulletin. 42, 1, p. 19-33 15 p.

Research output: Contribution to journalArticle

24 Scopus citations

Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub

Blizinsky, K. D., Diaz-Castro, B., Forrest, M. P., Schürmann, B., Bach, A. P., Martin-De-saavedra, M. D., Wang, L., Csernansky, J. G., Duan, J. & Penzes, P., Jul 26 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 30, p. 8520-8525 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Subcortical neuromorphometry in schizophrenia spectrum and bipolar disorders

Mamah, D., Alpert, K. I., Barch, D. M., Csernansky, J. G. & Wang, L., Jan 1 2016, In : NeuroImage: Clinical. 11, p. 276-286 11 p.

Research output: Contribution to journalArticle

33 Scopus citations
2015

Alterations in brain activation during cognitive empathy are related to social functioning in schizophrenia

Smith, M. J., Schroeder, M. P., Abram, S. V., Goldman, M. B., Parrish, T. B., Wang, X., Derntl, B., Habel, U., Decety, J., Reilly, J. L., Csernansky, J. G. & Breiter, H. C., Jan 1 2015, In : Schizophrenia bulletin. 41, 1, p. 211-222 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

A Phase II study of a histamine H3 receptor antagonist GSK239512 for cognitive impairment in stable schizophrenia subjects on antipsychotic therapy

Jarskog, L. F., Lowy, M. T., Grove, R. A., Keefe, R. S. E., Horrigan, J. P., Ball, M. P., Breier, A., Buchanan, R. W., Carter, C. S., Csernansky, J. G., Goff, D. C., Green, M. F., Kantrowitz, J. T., Keshavan, M. S., Laurelle, M., Lieberman, J. A., Marder, S. R., Maruff, P., McMahon, R. P., Seidman, L. J. & 1 others, Peykamian, M. A., May 1 2015, In : Schizophrenia Research. 164, 1-3, p. 136-142 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Cannabis-related episodic memory deficits and hippocampal morphological differences in healthy individuals and schizophrenia subjects

Smith, M. J., Cobia, D. J., Reilly, J. L., Gilman, J. M., Roberts, A. G., Alpert, K. I., Wang, L., Breiter, H. C. & Csernansky, J. G., Sep 1 2015, In : Hippocampus. 25, 9, p. 1042-1051 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Default mode connectivity in youth with perinatally acquired HIV

Herting, M. M., Uban, K. A., Williams, P. L., Gautam, P., Huo, Y., Malee, K., Yogev, R., Csernansky, J., Wang, L., Nichols, S., Van Dyke, R. & Sowell, E. R., Sep 1 2015, In : Medicine (United States). 94, 37

Research output: Contribution to journalArticle

17 Scopus citations

Differences in the neural correlates of affective responses in depressed and healthy women

Gollan, J. K., Buchanan, A., Connolly, M., Hoxha, D., Sankin, L., Csernansky, J. G. & Wang, X., Dec 30 2015, In : Psychiatry Research - Neuroimaging. 234, 3, p. 336-345 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Early life stress as a risk factor for substance use disorders: Clinical and neurobiological substrates

Varghese, S., Montalvo-Ortiz, J., Csernansky, J., Eiger, R., Herrold, A., Koola, M. & Dong, H., Jan 1 2015, In : Indian Journal of Psychological Medicine. 37, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Fractional anisotropy in individuals with schizophrenia and their nonpsychotic siblings

Harms, M. P., Akhter, K. D., Csernansky, J. G., Mori, S. & Barch, D. M., Jan 30 2015, In : Psychiatry Research - Neuroimaging. 231, 1, p. 87-91 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Morphometric analysis of amygdla and hippocampus shape in impulsively aggressive and healthy control subjects

Coccaro, E. F., Lee, R., McCloskey, M., Csernansky, J. G. & Wang, L., Oct 1 2015, In : Journal of Psychiatric Research. 69, p. 80-86 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Neural substrates of negativity bias in women with and without major depression

Gollan, J. K., Connolly, M., Buchanan, A., Hoxha, D., Rosebrock, L., Cacioppo, J., Csernansky, J. & Wang, X., Jul 1 2015, In : Biological Psychology. 109, p. 184-191 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Operationalizing protocol differences for EADC-ADNI manual hippocampal segmentation

Boccardi, M., Bocchetta, M., Ganzola, R., Robitaille, N., Redolfi, A., Duchesne, S., Jack, C. R., Frisoni, G. B., Bartzokis, G., Csernansky, J. G., De Leon, M. J., Detoledo-Morrell, L., Killiany, R. J., Lehericy, S., Malykhin, N., Pantel, J., Pruessner, J. C., Soininen, H. & Watson, C., Jan 1 2015, In : Alzheimer's and Dementia. 11, 2, p. 184-194 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Relationship between hippocampal atrophy and neuropathology markers: A 7T MRI validation study of the EADC-ADNI harmonized hippocampal segmentation protocol

Apostolova, L. G., Zarow, C., Biado, K., Hurtz, S., Boccardi, M., Somme, J., Honarpisheh, H., Blanken, A. E., Brook, J., Tung, S., Kraft, E., Lo, D., Ng, D., Alger, J. R., Vinters, H. V., Bocchetta, M., Duvernoy, H., Jack, C. R., Frisoni, G. B., Bartzokis, G. & 10 others, Csernansky, J. G., De Leon, M. J., Detoledo-Morrell, L., Killiany, R. J., Lehericy, S., Malykhin, N., Pantel, J., Pruessner, J. C., Soininen, H. & Watson, C., Jan 1 2015, In : Alzheimer's and Dementia. 11, 2, p. 139-150 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

The EADC-ADNI harmonized protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity

Frisoni, G. B., Jack, C. R., Bocchetta, M., Bauer, C., Frederiksen, K. S., Liu, Y., Preboske, G., Swihart, T., Blair, M., Cavedo, E., Grothe, M. J., Lanfredi, M., Martinez, O., Nishikawa, M., Portegies, M., Stoub, T., Ward, C., Apostolova, L. G., Ganzola, R., Wolf, D. & 53 others, Barkhof, F., Bartzokis, G., DeCarli, C., Csernansky, J. G., Detoledo-Morrell, L., Geerlings, M. I., Kaye, J., Killiany, R. J., Lehericy, S., Matsuda, H., O'Brien, J., Silbert, L. C., Scheltens, P., Soininen, H., Teipel, S., Waldemar, G., Fellgiebel, A., Barnes, J., Firbank, M., Gerritsen, L., Henneman, W., Malykhin, N., Pruessner, J. C., Wang, L., Watsonl, C., Wolf, H., Deleon, M., Pantel, J., Ferrari, C., Bosco, P., Pasqualetti, P., Duchesne, S., Duvernoy, H., Boccardi, M., Albert, M. S., Bennet, D., Camicioli, R., Collins, D. L., Dubois, B., Hampel, H., Denheijer, T., Hock, C., Jagust, W., Launer, L., Maller, J. J., Mueller, S., Sachdev, P., Simmons, A., Thompson, P. M., Visser, P. J., Wahlund, L. O., Weiner, M. W. & Winblad, B., Jan 1 2015, In : Alzheimer's and Dementia. 11, 2, p. 111-125 15 p.

Research output: Contribution to journalArticle

107 Scopus citations

White matter microstructure among youth with perinatally acquired HIV is associated with disease severity

Uban, K. A., Herting, M. M., Williams, P. L., Ajmera, T., Gautam, P., Huo, Y., Maleec, K. M., Yogev, R., Csernansky, J. G., Wang, L., Nichols, S. L. & Sowell, E. R., Jan 1 2015, In : AIDS. 29, 9, p. 1035-1044 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Altered cognitive development in the siblings of individuals with schizophrenia

Barch, D. M., Cohen, R. & Csernansky, J. G., Jan 1 2014, In : Clinical Psychological Science. 2, 2, p. 138-151 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness

Russell, T. A., Blizinsky, K. D., Cobia, D. J., Cahill, M. E., Xie, Z., Sweet, R. A., Duan, J., Gejman, P. V., Wang, L., Csernansky, J. G. & Penzes, P., 2014, In : Nature communications. 5, 4858.

Research output: Contribution to journalArticle

18 Scopus citations

Basal ganglia and thalamic morphology in schizophrenia and bipolar disorder

Womer, F. Y., Wang, L., Alpert, K. I., Smith, M. J., Csernansky, J. G., Barch, D. M. & Mamah, D., Aug 30 2014, In : Psychiatry Research - Neuroimaging. 223, 2, p. 75-83 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Cannabis-related working memory deficits and associated subcortical morphological differences in healthy individuals and schizophrenia subjects

Smith, M. J., Cobia, D. J., Wang, L., Alpert, K. I., Cronenwett, W. J., Goldman, M. B., Mamah, D., Barch, D. M., Breiter, H. C. & Csernansky, J. G., Mar 1 2014, In : Schizophrenia bulletin. 40, 2, p. 287-299 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice

Dong, H., Wang, S., Zeng, Z., Li, F., Montalvo-Ortiz, J., Tucker, C., Akhtar, S., Shi, J., Meltzer, H. Y., Rice, K. C. & Csernansky, J. G., May 31 2014, In : Psychopharmacology. 231, 24, p. 4711-4722 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation

Montalvo-Ortiz, J. L., Keegan, J., Gallardo, C., Gerst, N., Tetsuka, K., Tucker, C., Matsumoto, M., Fang, D., Csernansky, J. G. & Dong, H., May 2014, In : Neuropsychopharmacology. 39, 6, p. 1469-1478 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013
17 Scopus citations

Distinct abnormalities of the primate prefrontal cortex caused by ionizing radiation in early or midgestation

Selemon, L. D., Ceritoglu, C., Ratnanather, J. T., Wang, L., Harms, M. P., Aldridge, K., Begović, A., Csernansky, J. G., Miller, M. I. & Rakic, P., Apr 1 2013, In : Journal of Comparative Neurology. 521, 5, p. 1040-1053 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effects of davunetide on N-acetylaspartate and choline in dorsolateral prefrontal cortex in patients with schizophrenia

Jarskog, L. F., Dong, Z., Kangarlu, A., Colibazzi, T., Girgis, R. R., Kegeles, L. S., Barch, D. M., Buchanan, R. W., Csernansky, J. G., Goff, D. C., Harms, M. P., Javitt, D. C., Keefe, R. S., McEvoy, J. P., McMahon, R. P., Marder, S. R., Peterson, B. S. & Lieberman, J. A., Jun 1 2013, In : Neuropsychopharmacology. 38, 7, p. 1245-1252 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Structure-function relationship of working memory activity with hippocampal and prefrontal cortex volumes

Harms, M. P., Wang, L., Csernansky, J. G. & Barch, D. M., Jan 1 2013, In : Brain Structure and Function. 218, 1, p. 173-186 14 p.

Research output: Contribution to journalArticle

28 Scopus citations
2012

A longitudinal analysis of regional brain volumes in macaques exposed to x-irradiation in early gestation

Aldridge, K., Wang, L., Harms, M. P., Moffitt, A. J., Cole, K. K., Csernansky, J. G. & Selemon, L. D., Aug 14 2012, In : PloS one. 7, 8, e43109.

Research output: Contribution to journalArticle

7 Scopus citations

Cerebrospinal fluid proteins predict longitudinal hippocampal degeneration in early-stage dementia of the Alzheimer type

Wang, L., Fagan, A. M., Shah, A. R., Beg, M. F., Csernansky, J. G., Morris, J. C. & Holtzman, D. M., Oct 1 2012, In : Alzheimer Disease and Associated Disorders. 26, 4, p. 314-321 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Cognitively normal individuals with AD parents may be at risk for developing aging-related cortical thinning patterns characteristic of AD

Reiter, K., Alpert, K. I., Cobia, D. J., Kwasny, M. J., Morris, J. C., Csernansky, J. C. & Wang, L., Jul 2 2012, In : Neuroimage. 61, 3, p. 525-532 8 p.

Research output: Contribution to journalArticle

17 Scopus citations