John H Linehan

2013

BioInnovate Ireland - Fostering entrepreneurial activity through medical device innovation training

Bruzzi, M. S. & Linehan, J. H., Sep 2013, In: Annals of Biomedical Engineering. 41, 9, p. 1834-1840 7 p.

Research output: Contribution to journal › Article › peer-review

Medical device innovators and the 510(k) regulatory pathway: Implications of a survey-based assessment of industry experience-part 2: Medical device ecosystem and policy

Pietzsch, J. B., Zanchi, M. G. & Linehan, J. H., Jun 24 2013, In: Journal of Medical Devices, Transactions of the ASME. 7, 2, 021003.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2012

Medical Device Innovators and the 510(k) Regulatory Pathway: Implications of a Survey-Based Assessment of Industry Experience

Pietzsch, J. B., Zanchi, M. G. & Linehan, J. H., May 24 2012, In: Journal of Medical Devices, Transactions of the ASME. 6, 2, 021015.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2011

An integrated health-economic analysis of diagnostic and therapeutic strategies in the treatment of moderate-to-severe obstructive sleep apnea

Pietzsch, J. B., Garner, A., Cipriano, L. E. & Linehan, J. H., Jun 1 2011, In: Sleep. 34, 6, p. 695-709 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

122 Scopus citations

2010

Academic/industry challenges for medical device development

Linehan, J. H. & Chaney, A., Dec 22 2010, In: Science translational medicine. 2, 63

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

A case study of physician interaction in the medical device development process

Aquino Shluzas, L., Linehan, J. H. & Leifer, L. J., Jun 2010, In: Journal of Medical Devices, Transactions of the ASME. 4, 2, p. 1 1 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1999

Structure-function relationships in the pulmonary arterial tree

Dawson, C. A., Krenz, G. S., Karau, K. L., Haworth, S. T., Hanger, C. C. & Linehan, J. H., Feb 1999, In: Journal of applied physiology. 86, 2, p. 569-583 15 p.

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

1998

Accounting for the heterogeneity of capillary transit times in modeling multiple indicator dilution data

Audi, S. H., Linehan, J. H., Krenz, G. S. & Dawson, C. A., 1998, In: Annals of Biomedical Engineering. 26, 6, p. 914-930 17 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Anatomic distribution of pulmonary vascular compliance

Presson, R. G., Audi, S. H., Hanger, C. C., Zenk, G. M., Sidner, R. A., Linehan, J. H., Wagner, W. W. & Dawson, C. A., Jan 1998, In: Journal of applied physiology. 84, 1, p. 303-310 8 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Ascorbate-mediated transplasma membrane electron transport in pulmonary arterial endothelial cells

Merker, M. P., Olson, L. E., Bongard, R. D., Patel, M. K., Linehan, J. H. & Dawson, C. A., May 1998, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 274, 5 18-5, p. L685-L693

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Detection of lung inflammation using ¹⁴C-diazepam in the Multiple Indication Dilution (MID) method

Audi, S. H., Dawson, C. A., Linehan, J. H., Lin, W., Ahlf, S. B. & Roerig, D. L., Mar 20 1998, In: FASEB Journal. 12, 5

Research output: Contribution to journal › Article › peer-review

Feldkamp and circle-and-line cone-beam reconstruction for 3D micro-CT of vascular networks

Johnson, R. H., Hu, H., Haworth, S. T., Cho, P. S., Dawson, C. A. & Linehan, J. H., Apr 1998, In: Physics in Medicine and Biology. 43, 4, p. 929-940 12 p.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

In vivo measurement of real-time aortic segmental volume using the conductance catheter

Hettrick, D. A., Battocletti, J., Ackmann, J., Linehan, J. & Warltier, D. C., 1998, In: Annals of Biomedical Engineering. 26, 3, p. 431-440 10 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Kinetics of plasma membrane electron transport in a pulmonary endothelial cell-column

Olson, L. E., Merker, M. P., Bongard, R. D., Brantmeier, B. M., Audi, S. H., Linehan, J. H. & Dawson, C. A., 1998, In: Annals of Biomedical Engineering. 26, 1, p. 117-127 11 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Pulmonary disposition of lipophilic amine compounds in the isolated perfused rabbit lung

Audi, S. H., Dawson, C. A., Linehan, J. H., Krenz, G. S., Ahlf, S. B. & Roerig, D. L., Feb 1998, In: Journal of applied physiology. 84, 2, p. 516-530 15 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Transit time dispersion in the pulmonary arterial tree

Clough, A. V., Haworth, S. T., Hanger, C. C., Wang, J., Roerig, D. L., Linehan, J. H. & Dawson, C. A., Aug 1998, In: Journal of applied physiology. 85, 2, p. 565-574 10 p.

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Use of Multiple Indicator Dilution (MID) for detection of lung tissue composition changes

Roerig, D., Audi, S., Ahlf, S., Linehan, J. & Dawson, C., Mar 20 1998, In: FASEB Journal. 12, 5

Research output: Contribution to journal › Article › peer-review

1997

Detection of changes in lung tissue composition by multiple indicator dilution (MID)

Roerig, D., Audi, S., Ahlf, S., Linehan, J. & Dawson, C., Dec 1 1997, In: FASEB Journal. 11, 3

Research output: Contribution to journal › Article › peer-review

Direct calculation of mid sensitivity functions

Krenz, G. S., Skinner, C., Linehan, J. H. & Dawson, C. A., Dec 1 1997, In: FASEB Journal. 11, 3

Research output: Contribution to journal › Article › peer-review

Endothelial redox status and transplasma membrane electron transport

Olson, L. E., Bongard, R. D., Merker, M. P., Patel, M. K., Linehan, J. H. & Dawson, C. A., Dec 1 1997, In: FASEB Journal. 11, 3, p. A136

Research output: Contribution to journal › Article › peer-review

Flow-induced vasodilation in the ferret lung

Chammas, J. H., Rickaby, D. A., Guarin, M., Linehan, J. H., Hanger, C. C. & Dawson, C. A., Aug 1997, In: Journal of applied physiology. 83, 2, p. 495-502 8 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Pulmonary disposition of lipophilic amine compounds (LAC) in the isolated perfused rabbit lung (IPL)

Audi, S. H., Dawson, C. A., Linehan, J. H., Krenz, G. S., Ahlf, S. B. & Roerig, D. L., Dec 1 1997, In: FASEB Journal. 11, 3

Research output: Contribution to journal › Article › peer-review

Pulmonary endothelial thiazine uptake: Separation of cell surface reduction from intracellular reoxidation

Merker, M. P., Bongard, R. D., Linehan, J. H., Okamoto, Y., Vyprachticky, D., Brantmeier, B. M., Roerig, D. L. & Dawson, C. A., Apr 1997, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 272, 4 16-4, p. L673-L680

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Regional perfusion parameters from pulmonary microfocal angiograms

Clough, A. V., Linehan, J. H. & Dawson, C. A., Mar 1997, In: American Journal of Physiology - Heart and Circulatory Physiology. 272, 3 41-3, p. H1537-H1548

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

The effect of pH on lung toluidine blue O (TBO) reduction

Schulte, M. L., Dawson, C. A., Bongard, R. D., Audi, S. & Linehan, J. H., Dec 1 1997, In: FASEB Journal. 11, 3, p. A136

Research output: Contribution to journal › Article › peer-review

1996

An interpretation of ¹⁴C-urea and ¹⁴C-primidone extraction in isolated rabbit lungs

Audi, S. H., Dawson, C. A., Linehan, J. H., Krenz, G. S., Ahlf, S. B. & Roerig, D. L., 1996, In: Annals of Biomedical Engineering. 24, 3, p. 337-351 15 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Impact of angiotensin-converting enzyme substrate conformation on fractional hydrolysis in lung

Merker, M. P., Armitage, I. M., Audi, S. H., Kakalis, L. T., Linehan, J. H., Maehl, J. R., Roerig, D. L. & Dawson, C. A., Feb 1996, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 270, 2 14-2, p. L251-L259

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

In vitro and finite-element model investigation of the conductance technique for measurement of aortic segmental volume

Hettrick, D. A., Battocletti, J. H., Ackmann, J. J., Linehan, J. H. & Warltier, D. C., 1996, In: Annals of Biomedical Engineering. 24, 6, p. 675-684 10 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Mathematical model for the pulmonary disposition of lidocaine(lido) in the isolated rabbit lung (ipl)

Roerig, D., Audi, S., Ahlf, S., Linehan, J. & Dawson, C., Dec 1 1996, In: FASEB Journal. 10, 3

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Plasma protein binding and toluidine blue O (TBO) reduction in the pulmonary circulation

Olson, L. E., Bongard, R. D., Audi, S. H., Roerig, D. L., Linehan, J. H. & Dawson, C. A., Dec 1 1996, In: FASEB Journal. 10, 3, p. A100

Research output: Contribution to journal › Article › peer-review

Pulmonary angiotensin converting enzyme ligand binding kinetics

Audi, S. H., Schuster, D. P., Merker, M. P., Bongard, R. D., Linehan, J. H. & Dawson, C. A., Dec 1 1996, In: FASEB Journal. 10, 3

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

The effect of flow on the reduction of methylene blue (MB) and toluidine blue O (tbo) in the pulmonary circulation, ml. schulte

Dawson, C. A., Bongard, R. D., Audi, S. & Linehan, J. H., Dec 1 1996, In: FASEB Journal. 10, 3

Research output: Contribution to journal › Article › peer-review

1995

Estimation of the pulmonary capillary transport function in isolated rabbit lungs

Audi, S. H., Linehan, J. H., Krenz, G. S., Dawson, C. A., Ahlf, S. B. & Roerig, D. L., 1995, In: Journal of applied physiology. 78, 3, p. 1004-1014 11 p.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Reduction of thiazine dyes by bovine pulmonary arterial endothelial cells in culture

Bongard, R. D., Merker, M. P., Shundo, R., Okamoto, Y., Roerig, D. L., Linehan, J. H. & Dawson, C. A., 1995, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 269, 1 13-1, p. L78-L84

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Subpleural pulmonary microvascular pressures in the dog lung

Haworth, S. T., Rickaby, D. A., Linehan, J. H. & Dawson, C. A., 1995, In: Journal of applied physiology. 79, 2, p. 615-622 8 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

1994

Airway reopening pressure in isolated rat lungs

Naureckas, E. T., Dawson, C. A., Gerber, B. S., Gaver, D. P., Gerber, H. L., Linehan, J. H., Solway, J. & Samsel, R. W., 1994, In: Journal of applied physiology. 76, 3, p. 1372-1377 6 p.

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Edema development and recovery in neurogenic pulmonary edema

Maron, M. B., Holcomb, P. H., Dawson, C. A., Rickaby, D. A., Clough, A. V. & Linehan, J. H., 1994, In: Journal of applied physiology. 77, 3, p. 1155-1163 9 p.

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

First Pass Uptake in the Human Lung of Drugs Used during Anesthesia

Roerig, D. L., Ahlf, S. B., Dawson, C. A., Linehan, J. H. & Kampine, J. P., Jan 1 1994, In: Advances in Pharmacology. 31, C, p. 531-549 19 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Impact of parallel heterogeneity on a continuum model of the pulmonary arterial tree

Krenz, G. S., Lin, J., Dawson, C. A. & Linehan, J. H., 1994, In: Journal of applied physiology. 77, 2, p. 660-670 11 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Influence of hypoxia and serotonin on small pulmonary vessels

Al-Tinawi, A., Krenz, G. S., Rickaby, D. A., Linehan, J. H. & Dawson, C. A., 1994, In: Journal of applied physiology. 76, 1, p. 56-64 9 p.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Pulmonary capillary transport function from flow-limited indicators

Audi, S. H., Krenz, G. S., Linehan, J. H., Rickaby, D. A. & Dawson, C. A., 1994, In: Journal of applied physiology. 77, 1, p. 332-351 20 p.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Reduction and accumulation of methylene blue by the lung

Bongard, R. D., Krenz, G. S., Linehan, J. H., Roerig, D. L., Merker, M. P., Widell, J. L. & Dawson, C. A., 1994, In: Journal of applied physiology. 77, 3, p. 1480-1491 12 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Regional transit time estimation from image residue curves

Clough, A. V., Al-Tinawi, A., Linehan, J. H. & Dawson, C. A., Mar 1994, In: Annals of Biomedical Engineering. 22, 2, p. 128-143 16 p.

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

The vascular site of action of hypoxia in the neonatal pig lung

Nelin, L. D., Rickaby, D. A., Linehan, J. H. & Dawson, C. A., Jan 1994, In: Pediatric research. 35, 1, p. 25-29 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

1993

A distensible vessel model applied to hypoxic pulmonary vasoconstriction in the neonatal pig

Nelin, L. D., Krenz, G. S., Rickaby, D. A., Linehan, J. H. & Dawson, C. A., 1993, In: Journal of applied physiology. 74, 5, p. 2049-2056 8 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Angiotensin-converting enzyme preferentially hydrolyzes trans isomer of proline-containing substrate

Merker, M. P., Dawson, C. A., Bongard, R. D., Roerig, D. L., Haworth, S. T. & Linehan, J. H., 1993, In: Journal of applied physiology. 75, 4, p. 1519-1524 6 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Direct measurement of pulmonary microvascular distensibility

Hillier, S. C., Godbey, P. S., Hanger, C. C., Graham, J. A., Presson, R. G., Okada, O., Linehan, J. H., Dawson, C. A. & Wagner, W. W., 1993, In: Journal of applied physiology. 75, 5, p. 2106-2111 6 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Influence of temperature and plasma protein on doxorubicin uptake by isolated lungs

Bongard, R. D., Roerig, D. L., Johnston, M. R., Linehan, J. H. & Dawson, C. A., 1993, In: Drug Metabolism and Disposition. 21, 3, p. 428-434 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Model-free numerical deconvolution of recirculating indicator concentration curves

Clough, A. V., Cui, D., Linehan, J. H., Krenz, G. S., Dawson, C. A. & Maron, M. B., 1993, In: Journal of applied physiology. 74, 3, p. 1444-1453 10 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

1992

A fractal continuum model of the pulmonary arterial tree

Krenz, G. S., Linehan, J. H. & Dawson, C. A., 1992, In: Journal of applied physiology. 72, 6, p. 2225-2237 13 p.

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

John H Linehan

Research Output

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