Grants per year
Personal profile
Research Interests
retrovirus replication, reverse transcription, integration, virus assembly mechanisms, molecular genetics
Training Experience
1973 | Postdoctoral Fellowship, Albert Einstein College |
Education/Academic qualification
PhD, Cornell University
… → 1970
Research interests
- Biochemistry: Nucleic Acid
- Biochemistry: Proteins
- Genetic Engineering
- HIV Infection
- Molecular Biology
- Recombinant DNA
- Viral Oncology
- Virology
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Network
Grants
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A-015: Prazole Analogs to Block the Budding of Viruses
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/21
Project: Research project
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DF-007: Synthesis of a Matrix/Library of Prazole Analogs as Viral Budding Inhibitors
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/21
Project: Research project
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Controlling HIV release from cells with first-in-class drugs targeting virus budding
7/1/16 → 12/30/18
Project: Research project
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High Throughput Screening for Drugs that Disrupt Enveloped Virus Budding
Northwestern Memorial Foundation
1/1/12 → 12/31/13
Project: Research project
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HTS-001: High Throughput Screening for Small Molecule Inhibitors
Searle Funds at The Chicago Community Trust
1/1/11 → 12/31/17
Project: Research project
Research Output
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Tsg101 chaperone function revealed by HIV-1 assembly inhibitors
Strickland, M., Ehrlich, L. S., Watanabe, S., Khan, M., Strub, M. P., Luan, C. H., Powell, M. D., Leis, J., Tjandra, N. & Carter, C. A., Dec 1 2017, In: Nature Communications. 8, 1, 1391.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Rous sarcoma virus retropepsin and avian myeloblastosis virus retropepsin
Ridky, T. W. & Leis, J., Aug 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd., Vol. 1. p. 210-213 4 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Budding of enveloped viruses: Interferon-induced ISG15 - Antivirus mechanisms targeting the release process
Seo, E. J. & Leis, J., 2012, In: Advances in Virology. 2012, 532723.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15
Kuang, Z., Seo, E. J. & Leis, J., Jul 2011, In: Journal of virology. 85, 14, p. 7153-7161 9 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
The interferon-induced gene ISG15 blocks retrovirus release from cells late in the budding process
Pincetic, A., Kuang, Z., Seo, E. J. & Leis, J., May 2010, In: Journal of virology. 84, 9, p. 4725-4736 12 p.Research output: Contribution to journal › Article › peer-review
90 Scopus citations