Jonathan Peter Leis

Professor, Microbiology-Immunology
Senior Associate Dean for Research, Office of Finance and Administration
Driskill Graduate Training Program in Life Sciences

Phone+1 312 503 1166
Emailj-leis@northwestern.edu

Source: Scopus

Research activity per year

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Personal profile

Research Interests

retrovirus replication, reverse transcription, integration, virus assembly mechanisms, molecular genetics

Training Experience

1973	Postdoctoral Fellowship, Albert Einstein College

Education/Academic qualification

PhD, Cornell University

… → 1970

Research interests

Biochemistry: Nucleic Acid
Biochemistry: Proteins
Genetic Engineering
HIV Infection
Molecular Biology
Recombinant DNA
Viral Oncology
Virology

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Network

Recent external collaboration on country level. Dive into details by clicking on the dots.

2 Active
7 Finished

A-015: Prazole Analogs to Block the Budding of Viruses
Luan, C. & Leis, J. P.
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/21
Project: Research project
DF-007: Synthesis of a Matrix/Library of Prazole Analogs as Viral Budding Inhibitors
Luan, C. & Leis, J. P.
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/21
Project: Research project
Controlling HIV release from cells with first-in-class drugs targeting virus budding
Leis, J. P.
Campbell Foundation
7/1/16 → 12/30/18
Project: Research project
High Throughput Screening for Drugs that Disrupt Enveloped Virus Budding
Leis, J. P.
Northwestern Memorial Foundation
1/1/12 → 12/31/13
Project: Research project
HTS-001: High Throughput Screening for Small Molecule Inhibitors
Leis, J. P.
Searle Funds at The Chicago Community Trust
1/1/11 → 12/31/17
Project: Research project

5893 Citations
100 Article
18 Chapter
5 Review article
1 Short survey

Tsg101 chaperone function revealed by HIV-1 assembly inhibitors
Strickland, M., Ehrlich, L. S., Watanabe, S., Khan, M., Strub, M. P., Luan, C. H., Powell, M. D., Leis, J., Tjandra, N. & Carter, C. A., Dec 1 2017, In: Nature Communications. 8, 1, 1391.
Research output: Contribution to journal › Article › peer-review
14 Scopus citations
Rous sarcoma virus retropepsin and avian myeloblastosis virus retropepsin
Ridky, T. W. & Leis, J., Aug 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd., Vol. 1. p. 210-213 4 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter
Budding of enveloped viruses: Interferon-induced ISG15 - Antivirus mechanisms targeting the release process
Seo, E. J. & Leis, J., 2012, In: Advances in Virology. 2012, 532723.
Research output: Contribution to journal › Article › peer-review
8 Scopus citations
Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15
Kuang, Z., Seo, E. J. & Leis, J., Jul 2011, In: Journal of virology. 85, 14, p. 7153-7161 9 p.
Research output: Contribution to journal › Article › peer-review
38 Scopus citations
The interferon-induced gene ISG15 blocks retrovirus release from cells late in the budding process
Pincetic, A., Kuang, Z., Seo, E. J. & Leis, J., May 2010, In: Journal of virology. 84, 9, p. 4725-4736 12 p.
Research output: Contribution to journal › Article › peer-review
90 Scopus citations