Grants per year
Personal profile
Research Interests
retrovirus replication, reverse transcription, integration, virus assembly mechanisms, molecular genetics
Training Experience
| 1973 | Postdoctoral Fellowship, Albert Einstein College |
Education/Academic qualification
PhD, Cornell University
… → 1970
Research interests
- Biochemistry: Nucleic Acid
- Biochemistry: Proteins
- Genetic Engineering
- HIV Infection
- Molecular Biology
- Recombinant DNA
- Viral Oncology
- Virology
Fingerprint Dive into the research topics where Jonathan Peter Leis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Rous sarcoma virus
Medicine & Life Sciences
Avian Sarcoma Viruses
Medicine & Life Sciences
Viruses
Chemical Compounds
Retroviridae
Medicine & Life Sciences
HIV-1
Medicine & Life Sciences
Avian Myeloblastosis Virus
Medicine & Life Sciences
RNA-Directed DNA Polymerase
Medicine & Life Sciences
DNA
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2001 2021
DF-007: Synthesis of a Matrix/Library of Prazole Analogs as Viral Budding Inhibitors
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/21
Project: Research project
Controlling HIV release from cells with first-in-class drugs targeting virus budding
7/1/16 → 12/30/18
Project: Research project
Virus Release
Drug Delivery Systems
HIV
HIV Infections
Immune System
High Throughput Screening for Drugs that Disrupt Enveloped Virus Budding
Northwestern Memorial Foundation
1/1/12 → 12/31/13
Project: Research project
HTS-001: High Throughput Screening for Small Molecule Inhibitors
Searle Funds at The Chicago Community Trust
1/1/11 → 12/31/17
Project: Research project
Structure/Function Analysis of the Retrovirus Integrase
National Institute of Allergy and Infectious Diseases
1/12/09 → 12/31/11
Project: Research project
Research Output 1970 2017
5
Citations
(Scopus)
Tsg101 chaperone function revealed by HIV-1 assembly inhibitors
Strickland, M., Ehrlich, L. S., Watanabe, S., Khan, M., Strub, M. P., Luan, C. H., Powell, M. D., Leis, J., Tjandra, N. & Carter, C. A., Dec 1 2017, In : Nature Communications. 8, 1, 1391.Research output: Contribution to journal › Article
human immunodeficiency virus
Ubiquitin
inhibitors
HIV-1
assembly
Rous sarcoma virus retropepsin and avian myeloblastosis virus retropepsin
Ridky, T. W. & Leis, J., Aug 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd., Vol. 1. p. 210-213 4 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Avian Myeloblastosis Virus
Rous sarcoma virus
5
Citations
(Scopus)
Budding of enveloped viruses: Interferon-induced ISG15 - Antivirus mechanisms targeting the release process
Seo, E. J. & Leis, J., Dec 1 2012, In : Advances in Virology. 2012, 532723.Research output: Contribution to journal › Article
Virus Release
Interferons
Viruses
Innate Immunity
Cell Membrane
32
Citations
(Scopus)
Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15
Kuang, Z., Seo, E. J. & Leis, J., Jul 1 2011, In : Journal of virology. 85, 14, p. 7153-7161 9 p.Research output: Contribution to journal › Article
Retroviridae
interferons
Interferons
endosomes
protein transport
79
Citations
(Scopus)
The interferon-induced gene ISG15 blocks retrovirus release from cells late in the budding process
Pincetic, A., Kuang, Z., Seo, E. J. & Leis, J., May 1 2010, In : Journal of virology. 84, 9, p. 4725-4736 12 p.Research output: Contribution to journal › Article
Retroviridae
interferons
Interferons
Endosomal Sorting Complexes Required for Transport
Virus Release