Grants per year
Personal profile
Research Interests
We use imaging approaches to acquire large-scale recordings of neural activity during behavior, focusing on deep-brain areas implicated in neurological and psychiatric diseases, such as striatum. We use these tools to delineate the functional contribution of neuronal sub-populations in these brain areas to normal behavior in control subjects and pathological behavior in models for brain diseases. Our aim is to target these neural substrates to improve treatment outcomes for neuropsychiatric diseases.
Training Experience
| 2015 | Fellowship, Pfizer |
| 2018 | Postdoctoral Fellowship, Stanford University |
Education/Academic qualification
PhD, University of Washington
… → 2011
Research interests
- Brain and Nervous System
- Cell Imaging
- Drug Discovery
- Movement Disorders
- Nervous System Diseases
- Neurobiology
- Neuroscience
- Parkinson’s Disease
- Pharmacology
- Physiology
- Schizophrenia
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Grants
- 2 Active
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Dopamine’s Role in the Striatal Ensemble Dynamics of Learned Actions
1/1/20 → 12/31/22
Project: Research project
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Optical Dissection of the Neural Circuitry Controlling Sensorimotor Gating
Penzes, P., Radulovic, J. & Parker, J. G.
National Institute of Mental Health
3/15/19 → 2/28/21
Project: Research project
Research Output
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Diametric neural ensemble dynamics in parkinsonian and dyskinetic states
Parker, J. G., Marshall, J. D., Ahanonu, B., Wu, Y. W., Kim, T. H., Grewe, B. F., Zhang, Y., Li, J. Z., Ding, J. B., Ehlers, M. D. & Schnitzer, M. J., May 10 2018, In: Nature. 557, 7704, p. 177-182 6 p.Research output: Contribution to journal › Article › peer-review
70 Scopus citations -
Neural ensemble dynamics underlying a long-term associative memory
Grewe, B. F., Gründemann, J., Kitch, L. J., Lecoq, J. A., Parker, J. G., Marshall, J. D., Larkin, M. C., Jercog, P. E., Grenier, F., Li, J. Z., Lüthi, A. & Schnitzer, M. J., Mar 30 2017, In: Nature. 543, 7647, p. 670-675 6 p.Research output: Contribution to journal › Article › peer-review
117 Scopus citations -
Cellular level brain imaging in behaving mammals: An engineering approach
Hamel, E. J. O., Grewe, B. F., Parker, J. G. & Schnitzer, M. J., Apr 8 2015, In: Neuron. 86, 1, p. 140-159 20 p.Research output: Contribution to journal › Review article › peer-review
90 Scopus citations -
Transient activation of specific neurons in mice by selective expression of the capsaicin receptor
Güler, A. D., Rainwater, A., Parker, J. G., Jones, G. L., Argilli, E., Arenkiel, B. R., Ehlers, M. D., Bonci, A., Zweifel, L. S. & Palmiter, R. D., 2012, In: Nature communications. 3, 746.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
A behavioral genetics approach to understanding D1 receptor involvement in phasic dopamine signaling
Wall, V. Z., Parker, J. G., Fadok, J. P., Darvas, M., Zweifel, L. & Palmiter, R. D., Jan 2011, In: Molecular and Cellular Neuroscience. 46, 1, p. 21-31 11 p.Research output: Contribution to journal › Review article › peer-review
26 Scopus citations