Grants per year
- 1 - 25 out of 51 results
Search results
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Active
Prot #TCD601B203: A 12-Month, Randomized, Open-Label, Phase IIA Study Evaluating the Safety and Efficacy of Siplizumab in Combination with Belatacept and MPA Compared to Standard of Care Immunosuppression in de novo Renal Transplant Recipients (ASCEND)
Leventhal, J. R. (PD/PI)
2/21/24 → 2/21/27
Project: Research project
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The immunogenicity and pathogenicity of HLA-DQ in solid organ transplantation
Tambur, A. R. (PD/PI), Forte, E. (Co-Investigator), Forte, E. (Co-Investigator), Kelleher, N. L. (Co-Investigator), Leventhal, J. R. (Co-Investigator) & Thorp, E. B. (Co-Investigator)
National Institute of Allergy and Infectious Diseases
8/17/23 → 7/31/27
Project: Research project
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Improving the Lives of Transplant Patients: Devising a Method to Stop Long-Term Immunosuppressive Drug Treatment After Transplantation
Leventhal, J. R. (PD/PI), Mathew, J. (Co-PD/PI), Sambandam, Y. (Co-Investigator) & Zhu, F. (Co-Investigator)
Northwestern Memorial Hospital
9/1/21 → 8/31/25
Project: Research project
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Regenerative Engineering Training Program (RE-Training)
Ameer, G. A. (PD/PI), Ameer, G. A. (PD/PI), Leventhal, J. R. (Other) & Leventhal, J. R. (Other)
National Institute of Biomedical Imaging and Bioengineering
9/1/21 → 8/31/26
Project: Research project
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Informing Ethical Translation of Xenotransplantation Clinical Trials
Gordon, E. (PD/PI), Leventhal, J. R. (PD/PI), Leventhal, J. R. (PD/PI) & Leventhal, J. R. (PD/PI)
Hastings Center Inc., National Center for Advancing Translational Sciences
8/9/21 → 7/31/25
Project: Research project
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Protocol FCR001A2301 - A Randomized, Controlled, Multi-center, Safety and Efficacy Study of FCR001 Cell-Based Therapy Relative to a Tacrolimus and Mycophenolate-Based Regimen in De Novo Living Donor Renal Transplant Recipients, and Safety in FCR001 Donors
Leventhal, J. R. (PD/PI)
CTI Clinical Trial and Consulting Services, ImmunoFree, Inc.
10/2/19 → 10/2/25
Project: Research project
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Induction of Donor Specific Tolerance in Recipients of Living Kidney Allografts by Donor Stem Cell Infusion
Leventhal, J. R. (PD/PI) & Mathew, J. (Co-Investigator)
Regenerex LLC, Novartis Pharmaceuticals Corporation
7/1/14 → 8/31/25
Project: Research project
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Induction of Donor Specific Tolerance in Recipients of Living Kidney Allografts by Donor Stem Cell Infusion
Leventhal, J. R. (PD/PI) & Mathew, J. (Co-Investigator)
Regenerex LLC, Novartis Pharmaceuticals Corporation
7/1/14 → 8/31/25
Project: Research project
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Finished
Induction of Tolerance by Combinatorial Therapy w/ Donor Stem Cells and Expanded Recipient Treg cells in HLA-mismatched Kidney Transplant Recipients - Clinical Labor
Leventhal, J. R. (PD/PI)
Stanford University, California Institute for Regenerative Medicine
12/17/22 → 12/31/24
Project: Research project
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Mitochondrial transplantation by intra-arterial injection for prevention of acute kidney injury
Leventhal, J. R. (PD/PI)
12/22/21 → 12/31/23
Project: Research project
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Prot. VX20-880-101: A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus with Impaired Hypoglycemic Awareness and Severe Hypoglycemia
Leventhal, J. R. (PD/PI)
Vertex Pharmaceuticals Incorporated
12/14/21 → 12/14/24
Project: Research project
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Identification of the immunomodulatory mechanisms of nanocarrier-enhanced costimulation blockade in an allogeneic portal vein islet transplantation model
Scott, E. A. (PD/PI), Borja-Cacho, D. (Co-Investigator), Leventhal, J. R. (Co-Investigator) & Zhang, X. (Co-Investigator)
National Institute of Allergy and Infectious Diseases
9/24/21 → 8/31/23
Project: Research project
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Sites-Specific Nanofiber-Coated Regulatory T Cells for the Induction of Tolerance in Vascularized Composite Allotransplants
Mathew, J. (PD/PI), Mathew, J. (PD/PI), Leventhal, J. R. (Co-Investigator) & Leventhal, J. R. (Co-Investigator)
U.S. Army Medical Research and Materiel Command
9/15/21 → 9/14/24
Project: Research project
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Prot. FCR001B2201 (FREEDOM-2): A single-arm, multi-center, exploratory safety and efficacy study of FCR001 cell-based therapy to induce donor-specific tolerance in previously transplanted recipients of a kidney from a living donor, and safety in FCR001don
Leventhal, J. R. (PD/PI)
CTI Clinical Trial and Consulting Services, Regenerex LLC
8/31/21 → 8/31/24
Project: Research project
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Optimization of bead-free polyclonal expansion of regulatory T cells
Leventhal, J. R. (PD/PI), Mathew, J. (Co-PD/PI) & Sambandam, Y. (Co-Investigator)
12/1/20 → 1/31/23
Project: Research project
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Prot# CSL842_3001: A Double-Blind, Randomized-Withdrawal, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Human Plasma-Derived C1-Esterase Inhibitor as Add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection
Leventhal, J. R. (PD/PI)
6/4/18 → 6/4/21
Project: Research project
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T Cell Receptor Repertoire Analysis as a Biomarker for Predicting Graft Rejection in Transplant Recipients
Leventhal, J. R. (PD/PI) & Mathew, J. (PD/PI)
U.S. Army Medical Research and Materiel Command
9/30/17 → 3/31/22
Project: Research project
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Clinical Transplant Tolerance Induction by the Use of Ex Vivo Expanded Antigen Specific Regulatory T Cells
Leventhal, J. R. (PD/PI), Mathew, J. (Co-PD/PI) & Zhang, Z. J. (Co-Investigator)
Dr. Ralph and Marian Falk Medical Research Trust
11/30/16 → 8/30/18
Project: Research project
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Randomized Conversion of EBV+ Kidney Transplant Recipients of Living or Standard Criteria Donors at Three Months Post Transplantation to Belatacept with MPA or Belatacept with Low-Dose Tacrolimus (50% of Dose) Compared to Patients Remaining on Center Spec
Gallon, L. (PD/PI) & Leventhal, J. R. (Co-Investigator)
9/9/14 → 9/9/22
Project: Research project
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Delayed Tolerance in Recipients of Living Kidney Allografts by Donor Stem Cell Infusion
Leventhal, J. R. (PD/PI)
Regenerex LLC, Kentucky Science and Technology Corporation
10/19/12 → 2/28/14
Project: Research project
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Expansion of Facilitating Cells to Enhance Graft Tolerance
Leventhal, J. R. (PD/PI)
Northwestern Memorial Foundation
9/1/12 → 8/31/15
Project: Research project
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Induction of Donor Tolerance in Renal Transplants
Leventhal, J. R. (PD/PI)
Regenerex LLC, National Institute of Diabetes and Digestive and Kidney Diseases
9/15/11 → 6/30/14
Project: Research project