Joshua Brian Wechsler

  • 1255 Citations
20022020

Research output per year

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Research Output

  • 1255 Citations
  • 28 Article
  • 4 Review article
  • 2 Letter
  • 1 Comment/debate
2020

Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 28-37 10 p.

Research output: Contribution to journalArticle

Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jun 2020, In : Journal of Allergy and Clinical Immunology. 145, 6, p. 1629-1640.e4

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Mast cell activation in the systemic sclerosis esophagus

Tom, K., Mehta, B. K., Hoffmann, A., Aren, K., Carns, M., Lee, J., Martyanov, V., Popovich, D., Kosarek, N., Wood, T. A., Brenner, D., Carlson, D. A., Ostilla, L., Willcocks, E., Bryce, P., Wechsler, J. B., Whitfield, M. L. & Hinchcliff, M., 2020, (Accepted/In press) In : Journal of Scleroderma and Related Disorders.

Research output: Contribution to journalArticle

2 Scopus citations

Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 255-269 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Tutorial: Nutrition Therapy in Eosinophilic Esophagitis—Outcomes and Deficiencies

Bashaw, H., Schwartz, S., Kagalwalla, A. F. & Wechsler, J. B., May 1 2020, In : Journal of Parenteral and Enteral Nutrition. 44, 4, p. 600-609 10 p.

Research output: Contribution to journalReview article

1 Scopus citations
2019

Cellular Defects in CVID Patients with Chronic Lung Disease in the USIDNET Registry

The USIDNET Consortium, Aug 15 2019, In : Journal of Clinical Immunology. 39, 6, p. 569-576 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Histamine-driven responses are sustained via a bioactive metabolite

Velez, T. E., Byrne, A. J., Wechsler, J. B., Krier-Burris, R. A., Hulse, K. E. & Bryce, P. J., Jun 2019, In : Journal of Allergy and Clinical Immunology. 143, 6, p. 2287-2290.e1

Research output: Contribution to journalArticle

Oligoclonal immunoglobulin repertoire in biliary remnants of biliary atresia

Taylor, S. A., Malladi, P., Pan, X., Wechsler, J. B., Hulse, K. E., Perlman, H. R. & Whitington, P. F., Dec 1 2019, In : Scientific reports. 9, 1, 4508.

Research output: Contribution to journalArticle

Open Access

One-Hour Esophageal String Test: A Nonendoscopic Minimally Invasive Test That Accurately Detects Disease Activity in Eosinophilic Esophagitis

Ackerman, S. J., Kagalwalla, A. F., Hirano, I., Gonsalves, N., Katcher, P. M., Gupta, S., Wechsler, J. B., Grozdanovic, M., Pan, Z., Masterson, J. C., Du, J., Fantus, R. J., Alumkal, P., Lee, J. J., Ochkur, S., Ahmed, F., Capocelli, K., Melin-Aldana, H., Biette, K., Dubner, A. & 6 others, Amsden, K., Keeley, K., Sulkowski, M., Zalewski, A., Atkins, D. & Furuta, G. T., Oct 1 2019, In : The American journal of gastroenterology. 114, 10, p. 1614-1625 12 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes

Muir, A. B., Jensen, E. T., Wechsler, J. B., Menard-Katcher, P., Falk, G. W., Aceves, S. S., Furuta, G. T., Dellon, E. S., Rothenberg, M. E. & Spergel, J. M., Sep 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice. 7, 7, p. 2434-2436 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sialic acid–binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies

Legrand, F., Cao, Y., Wechsler, J. B., Zhu, X., Zimmermann, N., Rampertaap, S., Monsale, J., Romito, K., Youngblood, B. A., Brock, E. C., Makiya, M. A., Tomasevic, N., Bebbington, C., Maric, I., Metcalfe, D. D., Bochner, B. S. & Klion, A. D., Jun 2019, In : Journal of Allergy and Clinical Immunology. 143, 6, p. 2227-2237.e10

Research output: Contribution to journalArticle

15 Scopus citations
2018

Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jul 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 130-138.e1

Research output: Contribution to journalArticle

15 Scopus citations

Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis

Tappata, M., Eluri, S., Perjar, I., Hollyfield, J., Betancourt, R., Randall, C., Woosley, J. T., Wechsler, J. B. & Dellon, E. S., Oct 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 10, p. 2088-2092 5 p.

Research output: Contribution to journalLetter

4 Scopus citations

Biological therapies for eosinophilic gastrointestinal diseases

Wechsler, J. B. & Hirano, I., Jul 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 24-31.e2

Research output: Contribution to journalArticle

15 Scopus citations

Eosinophilic Esophagitis in Children: Endoscopic Findings at Diagnosis and Post-intervention

Bolton, S. M., Kagalwalla, A. F. & Wechsler, J. B., Jan 1 2018, In : Current gastroenterology reports. 20, 1, 4.

Research output: Contribution to journalReview article

2 Scopus citations
17 Scopus citations

Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis

Wechsler, J. B., Szabo, A., Hsu, C. L., Krier-Burris, R. A., Schroeder, H. A., Wang, M. Y., Carter, R. G., Velez, T. E., Aguiniga, L. M., Brown, J. B., Miller, M. L., Wershil, B. K., Barrett, T. A. & Bryce, P. J., May 1 2018, In : Mucosal Immunology. 11, 3, p. 861-870 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting

Spergel, J. M., Aceves, S. S., Kliewer, K., Gonsalves, N. P., Chehade, M., Wechsler, J. B., Groetch, M., Friedlander, J., Dellon, E. S., Book, W., Hirano, I., Muir, A. B., Cianferoni, A., Spencer, L., Liacouras, C. A., Cheng, E., Kottyan, L., Wen, T., Platts-Mills, T. & Rothenberg, M. E., Jul 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 48-53 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference

Dellon, E. S., Liacouras, C. A., Molina-Infante, J., Furuta, G. T., Spergel, J. M., Zevit, N., Spechler, S. J., Attwood, S. E., Straumann, A., Aceves, S. S., Alexander, J. A., Atkins, D., Arva, N. C., Blanchard, C., Bonis, P. A., Book, W. M., Capocelli, K. E., Chehade, M., Cheng, E., Collins, M. H. & 46 others, Davis, C. M., Dias, J. A., Di Lorenzo, C., Dohil, R., Dupont, C., Falk, G. W., Ferreira, C. T., Fox, A., Gonsalves, N. P., Gupta, S. K., Katzka, D. A., Kinoshita, Y., Menard-Katcher, C., Kodroff, E., Metz, D. C., Miehlke, S., Muir, A. B., Mukkada, V. A., Murch, S., Nurko, S., Ohtsuka, Y., Orel, R., Papadopoulou, A., Peterson, K. A., Philpott, H., Putnam, P. E., Richter, J. E., Rosen, R., Rothenberg, M. E., Schoepfer, A., Scott, M. M., Shah, N., Sheikh, J., Souza, R. F., Strobel, M. J., Talley, N. J., Vaezi, M. F., Vandenplas, Y., Vieira, M. C., Walker, M. M., Wechsler, J. B., Wershil, B. K., Wen, T., Yang, G-Y., Hirano, I. & Bredenoord, A. J., Oct 2018, In : Gastroenterology. 155, 4, p. 1022-1033.e10

Research output: Contribution to journalArticle

153 Scopus citations
2017

Efficacy of a 4-Food Elimination Diet for Children With Eosinophilic Esophagitis

Kagalwalla, A. F., Wechsler, J. B., Amsden, K., Schwartz, S., Makhija, M., Olive, A., Davis, C. M., Manuel-Rubio, M., Marcus, S., Shaykin, R., Sulkowski, M., Johnson, K., Ross, J. N., Riffle, M. E., Groetch, M., Melin-Aldana, H., Schady, D., Palac, H., Kim, K. Y. A., Wershil, B. K. & 2 others, Collins, M. H. & Chehade, M., Nov 2017, In : Clinical Gastroenterology and Hepatology. 15, 11, p. 1698-1707.e7

Research output: Contribution to journalArticle

68 Scopus citations

Utility of Gastric and Duodenal Biopsies during Follow-up Endoscopy in Children with Eosinophilic Esophagitis

Kaur, S., Rosen, J. M., Kriegermeier, A. A., Wechsler, J. B., Kagalwalla, A. F. & Brown, J. B., Oct 1 2017, In : Journal of pediatric gastroenterology and nutrition. 65, 4, p. 399-403 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Utility of Gastric and Duodenal Biopsies during Follow-up Endoscopy in Children with Eosinophilic Esophagitis

Kaur, S., Rosen, JM., Kriegermeir, AA., Wechsler, JB., Kagalwalla, AF. & Brown, JB., Oct 2017, In : Journal of pediatric gastroenterology and nutrition. 65, 4, p. 399-403 5 p.

Research output: Contribution to journalArticle

2016

IgE-associated food allergy alters the presentation of paediatric eosinophilic esophagitis

Pelz, B. J., Wechsler, J. B., Amsden, K., Johnson, K., Singh, A. M., Wershil, B. K., Kagalwalla, A. F. & Bryce, P. J., Nov 1 2016, In : Clinical and Experimental Allergy. 46, 11, p. 1431-1440 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
2015

Tetraspanin CD151 is a negative regulator of FcεRI-mediated mast cell activation

Abdala-Valencia, H., Bryce, P. J., Schleimer, R. P., Wechsler, J. B., Loffredo, L. F., Cook-Mills, J. M., Hsu, C. L. & Berdnikovs, S., Aug 15 2015, In : Journal of Immunology. 195, 4, p. 1377-1387 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Allergic mechanisms in eosinophilic esophagitis

Wechsler, J. B. & Bryce, P. J., Jun 2014, In : Gastroenterology Clinics of North America. 43, 2, p. 281-296 16 p.

Research output: Contribution to journalReview article

27 Scopus citations

Elimination diets in the management of eosinophilic esophagitis

Wechsler, J. B., Schwartz, S., Amsden, K. & Kagalwalla, A. F., May 24 2014, In : Journal of Asthma and Allergy. 7, p. 85-94 10 p.

Research output: Contribution to journalReview article

17 Scopus citations

IgE-mediated mast cell responses are inhibited by thymol-mediated, activation-induced cell death in skin inflammation

Wechsler, J. B., Hsu, C. L. & Bryce, P. J., Jun 2014, In : Journal of Allergy and Clinical Immunology. 133, 6, p. 1735-1743 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2013

Anaphylactic responses to histamine in mice utilize both histamine receptors 1 and 2

Wechsler, J. B., Schroeder, H. A., Byrne, A. J., Chien, K. B. & Bryce, P. J., Oct 2013, In : Allergy: European Journal of Allergy and Clinical Immunology. 68, 10, p. 1338-1340 3 p.

Research output: Contribution to journalArticle

16 Scopus citations
2011

TLR-induced activation of neutrophils promotes histamine production via a PI3 kinase dependent mechanism

Smuda, C., Wechsler, J. B. & Bryce, P. J., Dec 30 2011, In : Immunology Letters. 141, 1, p. 102-108 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
2008

Post-Infectious Functional Gastrointestinal Disorders in Children

Saps, M., Pensabene, L., Di Martino, L., Staiano, A., Wechsler, J., Zheng, X. & Di Lorenzo, C., Jun 2008, In : Journal of Pediatrics. 152, 6, p. 812-816.e1

Research output: Contribution to journalArticle

103 Scopus citations
2004

Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome [7]

Taub, J. W., Mundschau, G., Ge, Y., Poulik, J. M., Qureshi, F., Jensen, T., James, S. J., Matherly, L. H., Wechsler, J. & Crispino, J. D., Sep 1 2004, In : Blood. 104, 5, p. 1588-1589 2 p.

Research output: Contribution to journalLetter

80 Scopus citations
2003

Mutations in GATA1 in both transient myeloproliferative disorder and acute megakaryoblastic leukemia of Down syndrome

Greene, M. E., Mundschau, G., Wechsler, J., McDevitt, M., Gamis, A., Karp, J., Gurbuxani, S., Arceci, R. & Crispino, J. D., Jan 1 2003, In : Blood Cells, Molecules, and Diseases. 31, 3, p. 351-356 6 p.

Research output: Contribution to journalArticle

64 Scopus citations
2002

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

Wechsler, J., Greene, M., McDevitt, M. A., Anastasi, J., Karp, J. E., Le Beau, M. M. & Crispino, J. D., Sep 1 2002, In : Nature Genetics. 32, 1, p. 148-152 5 p.

Research output: Contribution to journalArticle

541 Scopus citations