Grants per year
Personal profile
Research Interests
I am an Assistant Professor of Urology at the Northwestern University Feinberg School of Medicine, as well as Section Chief of Robotic Surgery at the Jesse Brown VA Medical Center. I received his MD and PhD degrees from Northwestern University in 2005, completed my urology residency at Northwestern University in 2011, and a urologic oncology fellowship at Memorial Sloan-Kettering Cancer in 2012. My clinical efforts focus on minimally invasive and open urologic oncology with a particular interest in bladder and prostate cancer. My research interests focus on both the epigenetics and genetic mutations associated with cancer biology. Specifically,I am studying how chromatin remodeling genes play a role in bladder cancer. In addition, I am studying the “driver” mutations found in bladder cancer. In the future, I hope to develop novel systemic and intravesical therapies to improve survival of patients with bladder cancer.
Certifications and Licenses
Urology |
Training Experience
2006 | Internship, Northwestern University, Feinberg School of Medicine |
2011 | Residency, Northwestern University, Feinberg School of Medicine |
2012 | Fellowship, Memorial Sloan-Kettering Cancer Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, Northwestern University
… → 2005
Cell Biology, PhD, Northwestern University
… → 2003
Research interests keywords
- Big Data
- Bioinformatics
- Bladder Cancer
- Bladder and Urinary Tract
- Genetics
- Immunogenetics
- Immunology
- Oncology
- Robotic Surgery
- Translational Research
- Urology
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Prot #17000139BLC3004: SunRISe-5: A Phase 3, Randomized, Open-label, Multi-center Study Evaluating the Efficacy and Safety of TAR-200 Versus Investigator’s Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Guérin (BCG) and
Meeks, J. J. (PD/PI)
Janssen Research & Development, LLC
7/16/24 → 10/11/31
Project: Research project
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Prot #42756493BLC3004: MoonRISe-1: A Phase 3, Randomized Study Evaluating the Efficacy and Safety of TAR-210 Erdafitinib Intravesical Delivery System Versus Single Agent Intravesical Chemotherapy in Participants With Intermediate-risk Non-muscle Invasive
Meeks, J. J. (PD/PI)
Janssen Research & Development, LLC
7/16/24 → 12/31/28
Project: Research project
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An Investigation of Mechanisms of Response and Resistance to Enfortumab Vedotin in Urothelial Cancer
Meeks, J. J. (PD/PI) & Choy, B. (Co-Investigator)
U.S. Army Medical Research and Materiel Command
6/1/24 → 5/31/27
Project: Research project
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Development of TAR-200: A novel targeted releasing system designed to provide sustained delivery of gemcitabine for patients with bladder cancer
Daneshmand, S., Kamat, A. M., Shore, N. D., Meeks, J. J., Galsky, M. D., Jacob, J. M., van der Heijden, M. S., Williams, S. B., Powles, T., Chang, S. S., Catto, J. W. F., Psutka, S. P., Guerrero-Ramos, F., Xylinas, E., Miyake, M., Simone, G., Daniel, K., Sweiti, H., Cutie, C. & Necchi, A., 2025, (Accepted/In press) In: Urologic Oncology: Seminars and Original Investigations.Research output: Contribution to journal › Review article › peer-review
Open Access -
FGFR Inhibition in Urothelial Carcinoma
Li, R., Linscott, J., Catto, J. W. F., Daneshmand, S., Faltas, B. M., Kamat, A. M., Meeks, J. J., Necchi, A., Pradere, B., Ross, J. S., van der Heijden, M. S., van Rhijn, B. W. G. & Loriot, Y., Feb 2025, In: European urology. 87, 2, p. 110-122 13 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Association of Molecular Subtypes with Pathologic Response, PFS, and OS in a Phase II Study of COXEN with Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer
Lerner, S. P., McConkey, D. J., Tangen, C. M., Meeks, J. J., Flaig, T. W., Hua, X., Daneshmand, S., Alva, A. S., Lucia, M. S., Theodorescu, D., Goldkorn, A., Milowsky, M. I., Choi, W., Bangs, R., Gustafson, D. L., Plets, M. & Thompson, I. M., Jan 15 2024, In: Clinical Cancer Research. 30, 2, p. 444-449 6 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Author Correction: Oncolytic adenoviral therapy plus pembrolizumab in BCG-unresponsive non-muscle-invasive bladder cancer: the phase 2 CORE-001 trial(Nature Medicine, 10.1038/s41591-024-03025-3)
Li, R., Shah, P. H., Stewart, T. F., Nam, J. K., Bivalacqua, T. J., Lamm, D. L., Uchio, E. M., Geynisman, D. M., Jacob, J. M., Meeks, J. J., Dickstein, R., Pearce, S. M., Kang, S. H., Jung, S. I., Kamat, A. M., Burke, J. M., Keegan, K. A. & Steinberg, G. D., Aug 2024, In: Nature Medicine. 30, 8, p. 2372 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access2 Scopus citations -
Ensuring Successful Biomarker Studies in Bladder Preservation Clinical Trials for Non-muscle Invasive Bladder Cancer
McConkey, D. J., Baumann, B. C., Greenberg, S. C., DeGraff, D. J., Delacroix, S. E., Efstathiou, J. A., Foster, J., Groshen, S., Kadel, E. E., Khani, F., Kim, W. Y., Lerner, S. P., Levin, T., Liao, J. C., Milowsky, M. I., Meeks, J. J., Miyamoto, D. T., Mouw, K. W., Pietzak, E. J. & Solit, D. B. & 7 others, , Mar 12 2024, In: Bladder Cancer. 10, 1, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Additional file 2 of Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer
Iyyanki, T. (Creator), Zhang, B. (Creator), Wang, Q. (Creator), Hou, Y. (Creator), Jin, Q. (Creator), Xu, J. (Creator), Yang, H. (Creator), Liu, T. (Creator), Wang, X. (Creator), Song, F. (Creator), Luan, Y. (Creator), Yamashita, H. (Creator), Chien, R. (Creator), Lyu, H. (Creator), Zhang, L. (Creator), Wang, L. (Creator), Warrick, J. (Creator), Raman, J. D. (Creator), Meeks, J. J. (Creator), DeGraff, D. J. (Creator) & Yue, F. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14429354, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Subtype-associated_epigenomic_landscape_and_3D_genome_structure_in_bladder_cancer/14429354
Dataset
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Additional file 7 of Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer
Iyyanki, T. (Creator), Zhang, B. (Creator), Wang, Q. (Creator), Hou, Y. (Creator), Jin, Q. (Creator), Xu, J. (Creator), Yang, H. (Creator), Liu, T. (Creator), Wang, X. (Creator), Song, F. (Creator), Luan, Y. (Creator), Yamashita, H. (Creator), Chien, R. (Creator), Lyu, H. (Creator), Zhang, L. (Creator), Wang, L. (Creator), Warrick, J. (Creator), Raman, J. D. (Creator), Meeks, J. J. (Creator), DeGraff, D. J. (Creator) & Yue, F. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14429369, https://springernature.figshare.com/articles/dataset/Additional_file_7_of_Subtype-associated_epigenomic_landscape_and_3D_genome_structure_in_bladder_cancer/14429369
Dataset
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Additional file 6 of Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer
Iyyanki, T. (Creator), Zhang, B. (Creator), Wang, Q. (Creator), Hou, Y. (Creator), Jin, Q. (Creator), Xu, J. (Creator), Yang, H. (Creator), Liu, T. (Creator), Wang, X. (Creator), Song, F. (Creator), Luan, Y. (Creator), Yamashita, H. (Creator), Chien, R. (Creator), Lyu, H. (Creator), Zhang, L. (Creator), Wang, L. (Creator), Warrick, J. (Creator), Raman, J. D. (Creator), Meeks, J. J. (Creator), DeGraff, D. J. (Creator) & Yue, F. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14429366, https://springernature.figshare.com/articles/dataset/Additional_file_6_of_Subtype-associated_epigenomic_landscape_and_3D_genome_structure_in_bladder_cancer/14429366
Dataset
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Additional file 9 of Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer
Iyyanki, T. (Creator), Zhang, B. (Creator), Wang, Q. (Creator), Hou, Y. (Creator), Jin, Q. (Creator), Xu, J. (Creator), Yang, H. (Creator), Liu, T. (Creator), Wang, X. (Creator), Song, F. (Creator), Luan, Y. (Creator), Yamashita, H. (Creator), Chien, R. (Creator), Lyu, H. (Creator), Zhang, L. (Creator), Wang, L. (Creator), Warrick, J. (Creator), Raman, J. D. (Creator), Meeks, J. J. (Creator), DeGraff, D. J. (Creator) & Yue, F. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14429375, https://springernature.figshare.com/articles/dataset/Additional_file_9_of_Subtype-associated_epigenomic_landscape_and_3D_genome_structure_in_bladder_cancer/14429375
Dataset
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Additional file 3 of Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer
Iyyanki, T. (Creator), Zhang, B. (Creator), Wang, Q. (Creator), Hou, Y. (Creator), Jin, Q. (Creator), Xu, J. (Creator), Yang, H. (Creator), Liu, T. (Creator), Wang, X. (Creator), Song, F. (Creator), Luan, Y. (Creator), Yamashita, H. (Creator), Chien, R. (Creator), Lyu, H. (Creator), Zhang, L. (Creator), Wang, L. (Creator), Warrick, J. (Creator), Raman, J. D. (Creator), Meeks, J. J. (Creator), DeGraff, D. J. (Creator) & Yue, F. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14429357, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Subtype-associated_epigenomic_landscape_and_3D_genome_structure_in_bladder_cancer/14429357
Dataset