• 12245 Citations
1962 …2018
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Personal profile

Research Interests

My research involves the substantiation that bone marrow derived cells have an immunoregulatory capacity that can influence the induction of clinical tolerance (the elimination of maintenance immunosuppressive drugs). This includes the development of sophisticated monitoring techniques to detect the immune status of the recipient and the appearance of these regulatory cells in the bone marrow, peripheral blood, and transplanted organ in the recipient. I am currently conducting a clinical trial at Northwestern in 20 such HLA-identical living donor kidney transplant recipients of donor stem cells, along with the transplanted organ, and following the recipient for the detection of these immune regulatory functions.

Education/Academic qualification

MD, Albert Einstein College

… → 1961

Research interests

  • Autoimmunity
  • Immunology
  • Kidney
  • Microbiology
  • Stem Cells
  • Transplantation

Fingerprint Dive into the research topics where Joshua Miller is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 28 Similar Profiles
Kidney Transplantation Medicine & Life Sciences
Kidney Medicine & Life Sciences
Tacrolimus Medicine & Life Sciences
Allografts Medicine & Life Sciences
Transplants Medicine & Life Sciences
Immunosuppressive Agents Medicine & Life Sciences
Graft Rejection Medicine & Life Sciences
Immunosuppression Medicine & Life Sciences

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Grants 2007 2013

Research Output 1962 2018

2 Citations (Scopus)

Transcriptomic studies in tolerance: Lessons learned and the path forward

Kurian, S. M., Whisenant, T. C., Mathew, J., Miller, J. & Leventhal, J. R., May 1 2018, In : Human Immunology. 79, 5, p. 395-401 7 p.

Research output: Contribution to journalReview article

Graft Survival
Immunosuppressive Agents
3 Citations (Scopus)

Updated follow-up of a tolerance protocol in HLA-identical renal transplant pairs given donor hematopoietic stem cells

Leventhal, J. R., Miller, J., Mathew, J., Kurian, S., Roitberg-Tambur, A., Friedewald, J. J., Charrette, J. & Abecassis, M. M., May 1 2018, In : Human Immunology. 79, 5, p. 277-282 6 p.

Research output: Contribution to journalReview article

Hematopoietic Stem Cells
Tissue Donors
7 Citations (Scopus)

Immunoregulatory effects of everolimus on in vitro alloimmune responses

Levitsky, J., Miller, J., Huang, X., Gallon, L., Leventhal, J. R. & Mathew, J. M., Jun 1 2016, In : PloS one. 11, 6, e0156535.

Research output: Contribution to journalArticle

organ transplantation
in vitro studies
2 Citations (Scopus)

Low incidence of acute rejection in hepatitis B virus positive liver transplant recipients and the impact of hepatitis B immunoglobulin

Veerappan, A., VanWagner, L. B., Mathew, J. M., Huang, X., Miller, J., Lapin, B. & Levitsky, J., Apr 1 2016, In : Human Immunology. 77, 4, p. 367-374 8 p.

Research output: Contribution to journalArticle

Hepatitis B
Hepatitis B virus
30 Citations (Scopus)

Nonchimeric HLA-identical renal transplant tolerance: Regulatory immunophenotypic/genomic biomarkers

Leventhal, J. R., Mathew, J. M., Salomon, D. R., Kurian, S. M., Friedewald, J. J., Gallon, L., Konieczna, I., Tambur, A. R., Charette, J., Levitsky, J., Jie, C., Kanwar, Y. S., Abecassis, M. M. & Miller, J., Jan 1 2016, In : American Journal of Transplantation. 16, 1, p. 221-234 14 p.

Research output: Contribution to journalArticle

HLA Antigens