• 12290 Citations
1962 …2018

Research output per year

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Personal profile

Research Interests

My research involves the substantiation that bone marrow derived cells have an immunoregulatory capacity that can influence the induction of clinical tolerance (the elimination of maintenance immunosuppressive drugs). This includes the development of sophisticated monitoring techniques to detect the immune status of the recipient and the appearance of these regulatory cells in the bone marrow, peripheral blood, and transplanted organ in the recipient. I am currently conducting a clinical trial at Northwestern in 20 such HLA-identical living donor kidney transplant recipients of donor stem cells, along with the transplanted organ, and following the recipient for the detection of these immune regulatory functions.

Education/Academic qualification

MD, Albert Einstein College

… → 1961

Research interests

  • Autoimmunity
  • Immunology
  • Kidney
  • Microbiology
  • Stem Cells
  • Transplantation

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Grants

Research Output

Transcriptomic studies in tolerance: Lessons learned and the path forward

Kurian, S. M., Whisenant, T. C., Mathew, J., Miller, J. & Leventhal, J. R., May 2018, In : Human Immunology. 79, 5, p. 395-401 7 p.

Research output: Contribution to journalReview article

  • 2 Scopus citations

    Updated follow-up of a tolerance protocol in HLA-identical renal transplant pairs given donor hematopoietic stem cells

    Leventhal, J. R., Miller, J., Mathew, J. M., Kurian, S., Tambur, A. R., Friedewald, J., Charrette, J. & Abecassis, M. M., May 2018, In : Human Immunology. 79, 5, p. 277-282 6 p.

    Research output: Contribution to journalReview article

  • 4 Scopus citations

    Immunoregulatory effects of everolimus on in vitro alloimmune responses

    Levitsky, J., Miller, J., Huang, X., Gallon, L., Leventhal, J. R. & Mathew, J. M., Jun 1 2016, In : PloS one. 11, 6, e0156535.

    Research output: Contribution to journalArticle

  • 7 Scopus citations

    Low incidence of acute rejection in hepatitis B virus positive liver transplant recipients and the impact of hepatitis B immunoglobulin

    Veerappan, A., VanWagner, L. B., Mathew, J. M., Huang, X., Miller, J., Lapin, B. & Levitsky, J., Apr 1 2016, In : Human Immunology. 77, 4, p. 367-374 8 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Nonchimeric HLA-identical renal transplant tolerance: Regulatory immunophenotypic/genomic biomarkers

    Leventhal, J. R., Mathew, J. M., Salomon, D. R., Kurian, S. M., Friedewald, J. J., Gallon, L., Konieczna, I., Tambur, A. R., Charette, J., Levitsky, J., Jie, C., Kanwar, Y. S., Abecassis, M. M. & Miller, J., Jan 1 2016, In : American Journal of Transplantation. 16, 1, p. 221-234 14 p.

    Research output: Contribution to journalArticle

  • 30 Scopus citations