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Joshua N Leonard

  • 2511 Citations
19992024
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Personal profile

Education/Academic qualification

Chemical Engineering, PhD, University of California, Berkeley

… → 2006

Chemical Engineering, BS, Stanford University

… → 2000

Research interests

  • Cancer
  • Cellular engineering
  • Gene therapy
  • Immunology
  • Protein engineering
  • Synthetic biology
  • Systems biology

Fingerprint Dive into the research topics where Joshua N Leonard is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Biosensors Chemical Compounds
Synthetic Biology Medicine & Life Sciences
Cell- and Tissue-Based Therapy Medicine & Life Sciences
Biosensing Techniques Medicine & Life Sciences
Ligands Medicine & Life Sciences
Double-Stranded RNA Medicine & Life Sciences
RNA Interference Medicine & Life Sciences
Cell engineering Engineering & Materials Science

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2009 2024

Biotechnology Predoctoral Training Program

Leonard, J. N.

National Institute of General Medical Sciences

7/1/19 → 6/30/24

Project: Research project

biotechnology
trainee
training program
engineering
science

RoL: EAGER: DESYN-C3 Moving information across synthetic membranes via engineered sensors

Kamat, N. P. & Leonard, J. N.

National Science Foundation

12/1/18 → 11/30/20

Project: Research project

Membranes
Sensors
Chemical reactions
Cells
Catalysts

Design-driven engineering of robust mammalian sense-and-respond functions

Bagheri, N. & Leonard, J. N.

National Institute of Biomedical Imaging and Bioengineering

8/1/18 → 4/30/22

Project: Research project

Cell- and Tissue-Based Therapy
Synthetic Biology
Cell Engineering
Regenerative Medicine
Therapeutics

Elucidating a novel regulator of inflammation: the TLR4-Inhibitory Complex (TIC)

Bagheri, N. & Leonard, J. N.

National Institute of Allergy and Infectious Diseases

12/22/17 → 11/30/20

Project: Research project

Toll-Like Receptor 4
Inflammation
Ligands
Endotoxins
Clustered Regularly Interspaced Short Palindromic Repeats

Collaborative Research: EAGER: Customized cell biosensors for interrogating cancer cell physiology

Leonard, J. N.

National Science Foundation

9/1/17 → 8/31/20

Project: Research project

Cell Physiological Phenomena
Biosensing Techniques
Immunotherapy
Research
Neoplasms

Research Output 1999 2018

17 Citations (Scopus)

Advances, challenges, and opportunities in extracellular RNA biology: insights from the NIH exRNA Strategic Workshop

Li, K., Rodosthenous, R. S., Kashanchi, F., Gingeras, T., Gould, S. J., Kuo, L. S., Kurre, P., Lee, H., Leonard, J. N., Liu, H., Lombo, T. B., Momma, S., Nolan, J. P., Ochocinska, M. J., Pegtel, D. M., Sadovsky, Y., Sánchez-Madrid, F., Valdes, K. M., Vickers, K. C., Weaver, A. M. & 5 others, Witwer, K. W., Zeng, Y., Das, S., Raffai, R. L. & Howcroft, T. K., Apr 5 2018, In : JCI Insight. 3, 7

Research output: Contribution to journal › Review article

Open Access
RNA
Education
Research
RNA Transport
Transducers
7 Citations (Scopus)

Development of novel metabolite-responsive transcription factors via transposon-mediated protein fusion

Younger, A. K. D., Su, P. Y., Shepard, A. J., Udani, S. V., Cybulski, T. R., Tyo, K. E. J. & Leonard, J. N., Feb 1 2018, In : Protein Engineering, Design and Selection. 31, 2, p. 55-63 9 p.

Research output: Contribution to journal › Article

Transcription factors
Biosensing Techniques
Metabolites
Biosensors
Transcription Factors
2 Citations (Scopus)

Enrichment of extracellular vesicle subpopulations via affinity chromatography

Hung, M. E., Lenzini, S. B., Stranford, D. M. & Leonard, J. N., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc, p. 109-124 16 p. (Methods in Molecular Biology; vol. 1740).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Affinity Chromatography
Extracellular Vesicles
Centrifugation
Proteins
Population
2 Citations (Scopus)

Highly Stable, Ultrasmall Polymer-Grafted Nanobins (usPGNs) with Stimuli-Responsive Capability

Hong, B. J., Iscen, A., Chipre, A. J., Li, M. M., Lee, O. S., Leonard, J. N., Schatz, G. C. & Nguyen, S. T., Mar 1 2018, In : Journal of Physical Chemistry Letters. 9, 5, p. 1133-1139 7 p.

Research output: Contribution to journal › Article

carbopol 940
Cholesterol
stimuli
cholesterol
acrylic acid
2 Citations (Scopus)

Synthetic biology: Reframing cell therapy for cancer

Dolberg, T. B., Donahue, P. S. & Leonard, J. N., Feb 14 2018, In : Nature Chemical Biology. 14, 3, p. 204-205 2 p.

Research output: Contribution to journal › Comment/debate

Synthetic Biology
Cell- and Tissue-Based Therapy
Neoplasms