• 2590 Citations
19992024

Research output per year

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Research Output

2007

Enhanced preparation of adeno-associated viral vectors by using high hydrostatic pressure to selectively inactivate helper adenovirus

Leonard, J. N., Ferstl, P., Delgado, A. & Schaffer, D. V., Aug 1 2007, In : Biotechnology and Bioengineering. 97, 5, p. 1170-1179 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

High-throughput screening of gene function in stem cells using clonal microarrays

Ashton, R. S., Peltier, J., Fasano, C. A., O'Neill, A., Leonard, J., Temple, S., Schaffer, D. V. & Kane, R. S., Nov 1 2007, In : Stem Cells. 25, 11, p. 2928-2935 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

TLR3 deficiency in patients with herpes simplex encephalitis

Zhang, S. Y., Jouanguy, E., Ugolini, S., Smahi, A., Elain, G., Romero, P., Segal, D., Sancho-Shimizu, V., Lorenzo, L., Puel, A., Picard, C., Chapgier, A., Plancoulaine, S., Titeux, M., Cognet, C., Von Bernuth, H., Ku, C. L., Casrouge, A., Zhang, X. X., Barreiro, L. & 13 others, Leonard, J., Hamilton, C., Lebon, P., Héron, B., Vallée, L., Quintana-Murci, L., Hovnanian, A., Rozenberg, F., Vivier, E., Geissmann, F., Tardieu, M., Abel, L. & Casanova, J. L., Sep 14 2007, In : Science. 317, 5844, p. 1522-1527 6 p.

Research output: Contribution to journalArticle

700 Scopus citations
2006

Antiviral RNAi therapy: Emerging approaches for hitting a moving target

Leonard, J. N. & Schaffer, D. V., Mar 1 2006, In : Gene therapy. 13, 6, p. 532-540 9 p.

Research output: Contribution to journalReview article

73 Scopus citations
2005

Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape

Leonard, J. N. & Schaffer, D. V., Feb 1 2005, In : Journal of virology. 79, 3, p. 1645-1654 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

Computational design of RNA interference gene therapy strategies to treat HIV-1 infections and block viral escape

Leonard, J. N. & Schaffer, D. V., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. p. 8356-8357 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Purification of Aav gene therapy vectors by selectively inactivating helper adenovirus using high hydrostatic pressure

Leonard, J. N., Ferstl, P., Delgado, A. & Schaffer, D. V., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution