If you made any changes in Pure, your changes will be visible here soon.

Research Output 1999 2018

Filter
Review article
2018
17 Citations (Scopus)

Advances, challenges, and opportunities in extracellular RNA biology: insights from the NIH exRNA Strategic Workshop

Li, K., Rodosthenous, R. S., Kashanchi, F., Gingeras, T., Gould, S. J., Kuo, L. S., Kurre, P., Lee, H., Leonard, J. N., Liu, H., Lombo, T. B., Momma, S., Nolan, J. P., Ochocinska, M. J., Pegtel, D. M., Sadovsky, Y., Sánchez-Madrid, F., Valdes, K. M., Vickers, K. C., Weaver, A. M. & 5 others, Witwer, K. W., Zeng, Y., Das, S., Raffai, R. L. & Howcroft, T. K., Apr 5 2018, In : JCI Insight. 3, 7

Research output: Contribution to journalReview article

Open Access
RNA
Education
Research
RNA Transport
Transducers
2017
2 Citations (Scopus)

Building with intent: Technologies and principles for engineering mammalian cell-based therapies to sense and respond

Muldoon, J. J., Donahue, P. S., Dolberg, T. B. & Leonard, J. N., Dec 2017, In : Current Opinion in Biomedical Engineering. 4, p. 127-133 7 p.

Research output: Contribution to journalReview article

Cell engineering
Cell- and Tissue-Based Therapy
Technology
Artificial Receptors
Signal transduction
2016
8 Citations (Scopus)

Engineering cell-based therapies to interface robustly with host physiology

Schwarz, K. A. & Leonard, J. N., Oct 1 2016, In : Advanced Drug Delivery Reviews. 105, p. 55-65 11 p.

Research output: Contribution to journalReview article

Cell- and Tissue-Based Therapy
Cell Movement
Cues
Technology
Therapeutics
2015
192 Citations (Scopus)

Therapeutic applications of extracellular vesicles: Clinical promise and open questions

György, B., Hung, M. E., Breakefield, X. O. & Leonard, J. N., Jan 6 2015, In : Annual Review of Pharmacology and Toxicology. 55, p. 439-464 26 p.

Research output: Contribution to journalReview article

Tissue
Pathogens
Liposomes
Therapeutics
Modulation
2014

The Rise of Mammals

Leonard, J. N., Dec 19 2014, In : ACS synthetic biology. 3, 12, p. 878-879 2 p.

Research output: Contribution to journalReview article

Synthetic Biology
Mammals
Cells
Technology
Therapeutics
2013
102 Citations (Scopus)

FedExosomes: Engineering therapeutic biological nanoparticles that truly deliver

Marcus, M. E. & Leonard, J. N., May 7 2013, In : Pharmaceuticals. 6, 5, p. 659-680 22 p.

Research output: Contribution to journalReview article

Exosomes
Bioengineering
Nanoparticles
Exosome Multienzyme Ribonuclease Complex
Endosomes
2010
17 Citations (Scopus)

Biology by design: From top to bottom and back

Leonard, J. N., Fritz, B. R., Timmerman, L. E., Daringer, N. M. & Jewett, M. C., Dec 1 2010, In : Journal of Biomedicine and Biotechnology. 2010, 232016.

Research output: Contribution to journalReview article

Synthetic Biology
Biological systems
Equipment and Supplies
Therapeutics
34 Citations (Scopus)

Staying on message: Design principles for controlling nonspecific responses to siRNA

Samuel-Abraham, S. & Leonard, J. N., Dec 1 2010, In : FEBS Journal. 277, 23, p. 4828-4836 9 p.

Research output: Contribution to journalReview article

Small Interfering RNA
Chemical activation
RNA
Technology
Interferon Type I
2006
73 Citations (Scopus)

Antiviral RNAi therapy: Emerging approaches for hitting a moving target

Leonard, J. N. & Schaffer, D. V., Mar 1 2006, In : Gene therapy. 13, 6, p. 532-540 9 p.

Research output: Contribution to journalReview article

RNA Interference
Antiviral Agents
Therapeutics
Genes
Viruses