Grants per year
Personal profile
Research Interests
The Hultquist lab specializes in the development and adaptation of high-throughput, quantitative, systems-based approaches for use in primary models of disease to better understand the host-pathogen relationship. Leveraging diverse expertise in primary cell models, proteomic profiling, and functional genomics, we work at the intersection of systems biology and infectious disease, defining host-pathogen interactions and their consequences for replication and pathogenesis. Through these efforts, we ultimately hope to strengthen the bridge from big data to targeted discovery to clinical application for the development of personalized, host-driven therapies and the advancement of human health.
Training Experience
2018 | Postdoctoral Fellowship, J. David Gladstone Institutes |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Molecular Biology, PhD, University of Minnesota
… → 2013
Research interests keywords
- Big Data
- Genetic Engineering
- HIV Infection
- Infectious Diseases
- Infectious Diseases: Viral
- Molecular Biology
- Proteomics
- Systems Biology
- Virology
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Collaborations and top research areas from the last five years
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Turning off HIV White Noise: Switching from Long-Lived to Short-Lived Reservoir
Martinelli, E., Goyal, Y., Hultquist, J. F., Lorenzo Redondo, R. & Shukla, V.
National Institute of Allergy and Infectious Diseases
3/22/23 → 2/29/28
Project: Research project
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Project 1
Hartmann, E. M., Hultquist, J. F., Lorenzo Redondo, R., Ozer, E. A., Pickens, C. I., Qi, C., Singer, B., Walter, J. M. & Wunderink, R. G.
National Institute of Allergy and Infectious Diseases
1/1/23 → 12/31/27
Project: Research project
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Controlling HIV Latency By Manipulating CycT1 Turnover
University of California, San Francisco, National Institute of Allergy and Infectious Diseases
8/9/22 → 7/31/26
Project: Research project
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HARC Core 2: Genetics
University of California, San Francisco, National Institute of Allergy and Infectious Diseases
7/15/22 → 4/30/27
Project: Research project
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Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C
Soliman, S. H. A., Cisneros, W. J., Iwanaszko, M., Aoi, Y., Ganesan, S., Walter, M., Zeidner, J. M., Mishra, R. K., Kim, E-Y., Wolinsky, S. M., Hultquist, J. F. & Shilatifard, A., Mar 2023, In: Science Advances. 9, 10, eadf2468.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Serodominant SARS-CoV-2 Nucleocapsid Peptides Map to Unstructured Protein Regions
Vandervaart, J. P., Inniss, N. L., Ling-Hu, T., Minasov, G., Wiersum, G., Rosas-Lemus, M., Shuvalova, L., Achenbach, C. J., Hultquist, J. F., Satchell, K. J. F. & Bachta, K. E. R., May 2023, In: Microbiology Spectrum. 11, 3Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A functional map of HIV-host interactions in primary human T cells
Hiatt, J., Hultquist, J. F., McGregor, M. J., Bouhaddou, M., Leenay, R. T., Simons, L. M., Young, J. M., Haas, P., Roth, T. L., Tobin, V., Wojcechowskyj, J. A., Woo, J. M., Rathore, U., Cavero, D. A., Shifrut, E., Nguyen, T. T., Haas, K. M., Malik, H. S., Doudna, J. A., May, A. P., & 2 others , Dec 2022, In: Nature communications. 13, 1, 1752.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Application of CRISPR-Cas9 Gene Editing for HIV Host Factor Discovery and Validation
Cisneros, W. J., Cornish, D. & Hultquist, J. F., Aug 2022, In: Pathogens. 11, 8, 891.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Assessment of Virological Contributions to COVID-19 Outcomes in a Longitudinal Cohort of Hospitalized Adults
Simons, L. M., Lorenzo-Redondo, R., Gibson, M., Kinch, S. L., Vandervaart, J. P., Reiser, N. L., Eren, M., Lux, E., McNally, E. M., Tambur, A. R., Vaughan, D. E., Bachta, K. E. R., Demonbreun, A. R., Satchell, K. J. F., Achenbach, C. J., Ozer, E. A., Ison, M. G. & Hultquist, J. F., Mar 2022, In: Open Forum Infectious Diseases. 9, 3, ofac027.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations