Grants per year
Personal profile
Research Interests
The Hultquist lab specializes in the development and adaptation of high-throughput, quantitative, systems-based approaches for use in primary models of disease to better understand the host-pathogen relationship. Leveraging diverse expertise in primary cell models, proteomic profiling, and functional genomics, we work at the intersection of systems biology and infectious disease, defining host-pathogen interactions and their consequences for replication and pathogenesis. Through these efforts, we ultimately hope to strengthen the bridge from big data to targeted discovery to clinical application for the development of personalized, host-driven therapies and the advancement of human health.
Training Experience
| 2018 | Postdoctoral Fellowship, J. David Gladstone Institutes |
Expertise related to UN Sustainable Devlopment Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Molecular Biology, PhD, University of Minnesota
… → 2013
Research interests
- Big Data
- Genetic Engineering
- HIV Infection
- Infectious Diseases
- Infectious Diseases: Viral
- Molecular Biology
- Proteomics
- Systems Biology
- Virology
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Deciphering the Role of CPSF6 in HIV Infection
National Institute of Allergy and Infectious Diseases
7/13/21 → 6/30/26
Project: Research project
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Assessing the Risk of SARS-CoV-2 Remdesivir Resistance
Hultquist, J. F., Ison, M. G., Lorenzo Redondo, R. & Ozer, E. A.
National Institute of Allergy and Infectious Diseases
7/1/21 → 6/30/23
Project: Research project
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Regulation of SAMHD1 antiviral activity.
Albert Einstein College of Medicine, National Institute of Allergy and Infectious Diseases
7/1/20 → 6/30/25
Project: Research project
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Epidemiological, clinical, and functional characterization of genomic variation in SARS-CoV-2
Northwestern Memorial Hospital
5/1/20 → 12/31/21
Project: Research project
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Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins
Hiatt, J., Cavero, D. A., McGregor, M. J., Zheng, W., Budzik, J. M., Roth, T. L., Haas, K. M., Wu, D., Rathore, U., Meyer-Franke, A., Bouzidi, M. S., Shifrut, E., Lee, Y., Kumar, V. E., Dang, E. V., Gordon, D. E., Wojcechowskyj, J. A., Hultquist, J. F., Fontaine, K. A., Pillai, S. K. & 4 others, , May 11 2021, In: Cell reports. 35, 6, 109105.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Functional landscape of SARS-CoV-2 cellular restriction
Martin-Sancho, L., Lewinski, M. K., Pache, L., Stoneham, C. A., Yin, X., Becker, M. E., Pratt, D., Churas, C., Rosenthal, S. B., Liu, S., Weston, S., De Jesus, P. D., O'Neill, A. M., Gounder, A. P., Nguyen, C., Pu, Y., Curry, H. M., Oom, A. L., Miorin, L., Rodriguez-Frandsen, A. & 14 others, , Jun 17 2021, In: Molecular cell. 81, 12, p. 2656-2668.e8Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells
Yin, X., Riva, L., Pu, Y., Martin-Sancho, L., Kanamune, J., Yamamoto, Y., Sakai, K., Gotoh, S., Miorin, L., De Jesus, P. D., Yang, C. C., Herbert, K. M., Yoh, S., Hultquist, J. F., García-Sastre, A. & Chanda, S. K., Jan 12 2021, In: Cell reports. 34, 2, 108628.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Molecular epidemiology in the HIV and SARS-CoV-2 pandemics
Lorenzo-Redondo, R., Ozer, E. A., Achenbach, C. J., D'Aquila, R. T. & Hultquist, J. F., Jan 2021, In: Current Opinion in HIV and AIDS. 16, 1, p. 11-24 14 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Patterns and persistence of SARS-CoV-2 IgG antibodies in Chicago to monitor COVID-19 exposure
Demonbreun, A. R., McDade, T. W., Pesce, L., Vaught, L. A., Reiser, N. L., Bogdanovic, E., Velez, M. P., Hsieh, R. R., Simons, L. M., Saber, R., Ryan, D. T., Ison, M. G., Hultquist, J. F., Wilkins, J. T., D'Aquila, R. T., Mustanski, B. & McNally, E. M., May 10 2021, In: JCI Insight. 6, 9, e146148.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations