Grants per year
Personal profile
Research Interests
The Hultquist lab specializes in the development and adaptation of high-throughput, quantitative, systems-based approaches for use in primary models of disease to better understand the host-pathogen relationship. Leveraging diverse expertise in primary cell models, proteomic profiling, and functional genomics, we work at the intersection of systems biology and infectious disease, defining host-pathogen interactions and their consequences for replication and pathogenesis. Through these efforts, we ultimately hope to strengthen the bridge from big data to targeted discovery to clinical application for the development of personalized, host-driven therapies and the advancement of human health.
Training Experience
2018 | Postdoctoral Fellowship, J. David Gladstone Institutes |
Education/Academic qualification
Molecular Biology, PhD, University of Minnesota
… → 2013
PhD, University of Minnesota Twin Cities
… → 2013
Research interests
- Big Data
- Genetic Engineering
- HIV Infection
- Infectious Diseases
- Infectious Diseases: Viral
- Molecular Biology
- Proteomics
- Systems Biology
- Virology
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Network
Grants
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Epidemiological and clinical characterization of genomic variation in SARS-CoV-2
Hultquist, J. F. & Ozer, E. A.
University of Chicago, National Center for Advancing Translational Sciences
7/13/20 → 6/30/21
Project: Research project
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Regulation of SAMHD1 antiviral activity.
Albert Einstein College of Medicine, National Institute of Allergy and Infectious Diseases
7/1/20 → 6/30/25
Project: Research project
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COVID19: Production of protein array for serum antibody screening
Achenbach, C. J., Satchell, K. J. F., Hultquist, J. F. & Platanias, L. C.
7/1/20 → 7/31/21
Project: Research project
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Epidemiological, clinical, and functional characterization of genomic variation in SARS-CoV-2
Northwestern Memorial Hospital
5/1/20 → 12/31/21
Project: Research project
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Third Coast Center for AIDS Research
Achenbach, C. J., Benbow, N. D., Burnett-Zeigler, I. E., Cianci, G. C., D'Aquila, R. T., D'Aquila, R. T., Hirschhorn, L. R., Janulis, P. F., Lorenzo Redondo, R., Moskowitz, J. T., Mustanski, B., Palella Jr, F. J., Phillips II, G., Taiwo, B. O., Taylor, H. E., Hultquist, J. F. & Hope, T. J.
National Institute of Allergy and Infectious Diseases
4/1/20 → 4/30/25
Project: Research project
Research Output
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A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways
Lorenzo-Redondo, R., Nam, H. H., Roberts, S. C., Simons, L. M., Jennings, L. J., Qi, C., Achenbach, C. J., Hauser, A. R., Ison, M. G., Hultquist, J. F. & Ozer, E. A., Dec 2020, In: EBioMedicine. 62, 103112.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A systems approach to infectious disease
Eckhardt, M., Hultquist, J. F., Kaake, R. M., Hüttenhain, R. & Krogan, N. J., Jun 1 2020, In: Nature Reviews Genetics. 21, 6, p. 339-354 16 p.Research output: Contribution to journal › Review article › peer-review
13 Scopus citations -
Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core
Selyutina, A., Persaud, M., Simons, L. M., Bulnes-Ramos, A., Buffone, C., Martinez-Lopez, A., Scoca, V., Di Nunzio, F., Hiatt, J., Marson, A., Krogan, N. J., Hultquist, J. F. & Diaz-Griffero, F., Mar 17 2020, In: Cell reports. 30, 11, p. 3766-3777.e6Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1
Du, Y., Hultquist, J. F., Zhou, Q., Olson, A., Tseng, Y., Zhang, T. H., Hong, M., Tang, K., Chen, L., Meng, X., McGregor, M. J., Dai, L., Gong, D., Martin-Sancho, L., Chanda, S., Li, X., Bensenger, S., Krogan, N. J. & Sun, R., Dec 1 2020, In: Nature communications. 11, 1, 2449.Research output: Contribution to journal › Article › peer-review
Open Access -
ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection
Hüttenhain, R., Xu, J., Burton, L. A., Gordon, D. E., Hultquist, J. F., Johnson, J. R., Satkamp, L., Hiatt, J., Rhee, D. Y., Baek, K., Crosby, D. C., Frankel, A. D., Marson, A., Harper, J. W., Alpi, A. F., Schulman, B. A., Gross, J. D. & Krogan, N. J., Jul 10 2019, In: Cell Host and Microbe. 26, 1, p. 86-99.e7Research output: Contribution to journal › Article › peer-review
10 Scopus citations