Karen K L Mestan

  • 1305 Citations

Research output per year

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Personal profile

Research Interests

Why do some premature infants experience adverse outcomes, while others do not? Dr. Mestan is an attending neonatologist at Lurie Children's Hospital and Northwestern University Feinberg School of Medicine, whose research focuses on identifying biochemical, environmental, and genetic markers for preterm birth and its complications. Understanding these markers and the scientific mechanisms behind them can lead to new approaches and therapies to prevent complications of preterm birth, such as chronic lung and heart problems, poor growth, and neurodevelopmental delays in early childhood.

Translational research in identifying biomarkers and mechanisms by which placental vascular dysfunction leads to neonatal lung disease and its long-term health sequelae.

Management and prevention of neonatal chronic lung diseases, such as bronchopulmonary dysplasia and neonatal pulmonary hypertension. Clinical care coordination for medically complex infants.

Certifications and Licenses

Neonatal-Perinatal Medicine

Training Experience

1999Residency, University of Chicago
2002Fellowship, University of Chicago

Education/Academic qualification

MD, Chicago Medical School

… → 1996

Research interests

  • Clinical Research
  • Developmental-Behavioral Pediatrics
  • Genomics
  • Lungs / Breathing Problems
  • Maternal-Child Health
  • Neonatology
  • Pediatrics
  • Stem Cells

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Research Output

The impact of placental pathology discordance in multiple gestation pregnancies on bronchopulmonary dysplasia-associated pulmonary hypertension

Franklin, A., Yallapragada, S. G., Birkett, R., Grobman, W., Ernst, L. M. & Mestan, K., Jan 1 2020, In : Pulmonary Circulation. 10, 1

Research output: Contribution to journalArticle

Open Access
  • Cord blood alpha klotho is decreased in small for gestational age preterm infants with placental lesions of accelerated aging

    Franklin, A. D., Saqibuddin, J., Stephens, K., Birkett, R., Marsden, L., Ernst, L. M. & Mestan, K. K., Nov 2019, In : Placenta. 87, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Racial differences in placental pathology among very preterm births

    Matoba, N., Yallapragada, S., Davis, M. M., Ernst, L. M., Collins, J. W. & Mestan, K. K., Aug 2019, In : Placenta. 83, p. 37-42 6 p.

    Research output: Contribution to journalArticle

  • Variations in Umbilical Cord Hematopoietic and Mesenchymal Stem Cells With Bronchopulmonary Dysplasia

    Chaudhury, S., Saqibuddin, J., Birkett, R., Falcon-Girard, K., Kraus, M., Ernst, L. M., Grobman, W. & Mestan, K. K., Nov 14 2019, In : Frontiers in Pediatrics. 7, 475.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations