Grants per year
Personal profile
Research Interests
Why do some premature infants experience adverse outcomes, while others do not? Dr. Mestan is an attending neonatologist at Lurie Children's Hospital and Northwestern University Feinberg School of Medicine, whose research focuses on identifying biochemical, environmental, and genetic markers for preterm birth and its complications. Understanding these markers and the scientific mechanisms behind them can lead to new approaches and therapies to prevent complications of preterm birth, such as chronic lung and heart problems, poor growth, and neurodevelopmental delays in early childhood.
Translational research in identifying biomarkers and mechanisms by which placental vascular dysfunction leads to neonatal lung disease and its long-term health sequelae.
Management and prevention of neonatal chronic lung diseases, such as bronchopulmonary dysplasia and neonatal pulmonary hypertension. Clinical care coordination for medically complex infants.
Certifications and Licenses
Neonatal-Perinatal Medicine |
Training Experience
1999 | Residency, University of Chicago |
2002 | Fellowship, University of Chicago |
Education/Academic qualification
MD, Chicago Medical School
… → 1996
Research interests
- Clinical Research
- Developmental-Behavioral Pediatrics
- Genomics
- Lungs / Breathing Problems
- Maternal-Child Health
- Neonatology
- Pediatrics
- Stem Cells
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Grants
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Cord Blood Adductomics in Bronchopulmonary Dysplasia
National Institute of Child Health and Human Development, National Institutes of Health
12/10/19 → 8/31/21
Project: Research project
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Integrating Environmental Cues at the Maternal-Fetal Vascular Interface
University of California at San Francisco, National Institutes of Health
7/15/19 → 4/30/24
Project: Research project
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Integrating Environmental Cues at the Maternal-Fetal Vascular Interface
University of California at San Francisco, National Institutes of Health
7/15/19 → 4/30/24
Project: Research project
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The Role of Placental Maternal Vascular Underperfusion in Neonatal Pulmonary Hypertension
National Heart, Lung, and Blood Institute, National Institutes of Health
2/15/18 → 1/30/23
Project: Research project
Research Output
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Understanding Racial Disparities of Preterm Birth Through the Placenta
Matoba, N., Mestan, K. K. & Collins, J. W., 2021, (Accepted/In press) In: Clinical Therapeutics.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Moving the dial on prenatal stress mechanisms of neurodevelopmental vulnerability to mental health problems: A personalized prevention proof of concept
Wakschlag, L. S., Tandon, D., Krogh-Jespersen, S., Petitclerc, A., Nielsen, A., Ghaffari, R., Mithal, L., Bass, M., Ward, E., Berken, J., Fareedi, E., Cummings, P., Mestan, K., Norton, E. S., Grobman, W., Rogers, J., Moskowitz, J. & Alshurafa, N., 2020, (Accepted/In press) In: Developmental Psychobiology.Research output: Contribution to journal › Article › peer-review
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Soluble Klotho, a biomarker and therapeutic strategy to reduce bronchopulmonary dysplasia and pulmonary hypertension in preterm infants
Batlahally, S., Franklin, A., Damianos, A., Huang, J., Chen, P., Sharma, M., Duara, J., Keerthy, D., Zambrano, R., Shehadeh, L. A., Martinez, E. C., DeFreitas, M. J., Kulandavelu, S., Abitbol, C. L., Freundlich, M., Kanashiro-Takeuchi, R. M., Schmidt, A., Benny, M., Wu, S., Mestan, K. K. & 1 others, , Dec 1 2020, In: Scientific reports. 10, 1, 12368.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The impact of placental pathology discordance in multiple gestation pregnancies on bronchopulmonary dysplasia-associated pulmonary hypertension
Franklin, A., Yallapragada, S., Birkett, R., Grobman, W., Ernst, L. M. & Mestan, K., Jan 2020, In: Pulmonary Circulation. 10, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Cord blood alpha klotho is decreased in small for gestational age preterm infants with placental lesions of accelerated aging
Franklin, A. D., Saqibuddin, J., Stephens, K., Birkett, R., Marsden, L., Ernst, L. & Mestan, K. K., Nov 2019, In: Placenta. 87, p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations