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Research Output

1989
20 Scopus citations
1992

PEEP is necessary for exogenous surfactant to reduce pulmonary edema in canine aspiration pneumonitis

Zucker, A. R., Holm, B. A., Crawford, G. P., Ridge, K., Wood, L. D. H. & Sznajder, J. I., Jan 1 1992, In : Journal of Applied Physiology. 73, 2, p. 679-686 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
1993

ANF decreases active sodium transport and increases alveolar epithelial permeability in rats

Olivera, W., Ridge, K., Wood, L. D. H. & Sznajder, J. I., Jan 1 1993, In : Journal of Applied Physiology. 75, 4, p. 1581-1586 6 p.

Research output: Contribution to journalArticle

30 Scopus citations
1994
90 Scopus citations

Alveolar type II cell Na,K-ATPase is upregulated during mechanical ventilation-induced pulmonary edema

Sznajder, J. I., Ridge, K. M., Harris, Z. L., Olivera, W., Curiet, C., Venezuely, C. & Rutschman, D. H., Jan 1 1994, In : CHEST. 105, 3 SUPPL., p. 116S-117S

Research output: Contribution to journalArticle

11 Scopus citations
1995

Lung liquid clearance and NA,K-ATPase during acute hyperoxia and recovery in rats

Olivera, W. G., Ridge, K. M. & Sznajder, J. I., Jan 1 1995, In : American Journal of Respiratory and Critical Care Medicine. 152, 4 I, p. 1229-1234 6 p.

Research output: Contribution to journalArticle

101 Scopus citations

Mechanisms of lung liquid clearance during hyperoxia in isolated rat lungs

Sznajder, J. I., Olivera, W. G., Ridge, K. M. & Rutschman, D. H., Jan 1 1995, In : American journal of respiratory and critical care medicine. 151, 5, p. 1519-1525 7 p.

Research output: Contribution to journalArticle

79 Scopus citations
1996

Dopamine increases active na+ transport and lung liquid clearance

Barnard, M. L., Ridge, K. M., Qlivara, W. G., Rirtschman, D. H., Ashwath-Naravan, R. & Sznaider, J. I., Dec 1 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

2 Scopus citations

Hydrogen peroxide increases Na+/K+-ATPase function in alveolar type II cells

González-Flecha, B., Evelson, P., Ridge, K. & Sznajder, J. I., May 21 1996, In : Biochimica et Biophysica Acta - General Subjects. 1290, 1, p. 46-52 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Hyperbaric oxygenation upregulates rat lung Na,K-ATPase

Harris, Z. L., Ridge, K. M., Gonzalez-Flecha, B., Gottlieb, L., Zucker, A. & Sznajder, J. I., Mar 1 1996, In : European Respiratory Journal. 9, 3, p. 472-477 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Increased expression of gelatinases and collagenase in rat lungs exposed to 100% oxygen

Pardo, A., Selman, M., Ridge, K., Barrios, R. & Sznajder, J. I., Jan 1 1996, In : American journal of respiratory and critical care medicine. 154, 4 I, p. 1067-1075 9 p.

Research output: Contribution to journalArticle

77 Scopus citations
1997

Alpha-2 Na,K-ATPase contributes to lung liquid clearance

Ridge, K., Olivera, W., Rutschman, D. H., Mercer, R. W., Uhal, B., Horowitz, S., Hughes, F., Factor, P., Barnard, M. L. & Sznajder, J. I., Jan 1 1997, In : Annals of the New York Academy of Sciences. 834, p. 651-652 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dexamethasone upregulates the Na-K-ATPase in rat alveolar epithelial cells

Barquin, N., Ciccolella, D. E., Ridge, K. M. & Sznajder, J. I., Nov 17 1997, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 273, 4 17-4, p. L825-L830

Research output: Contribution to journalArticle

62 Scopus citations

Differential effects of adenoviral-mediated transfer of Na+/K+-ATPase subunit genes in lung epithelial cells

Factor, P., Senne, C., Ridge, K., Jaffe, H. A. & Sznajder, J. I., Jan 1 1997, In : Chest. 111, 6 SUPPL., p. 110S-111S

Research output: Contribution to journalArticle

2 Scopus citations

Differential expression of Na-K-ATPase isoforms in rat alveolar epithelial cells

Ridge, K. M., Rutschman, D. H., Factor, P., Katz, A. I., Bertorello, A. M. & Sznajder, J. I., Jul 1 1997, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 273, 1 17-1, p. L246-L255

Research output: Contribution to journalArticle

82 Scopus citations

Effects of adenoviral mediated transfer of Na+,K+-ATPase subunit genes to alveolar epithelial cells

Factor, P., Senne, C., Ridge, K., Jaffe, H. A., Blanco, G., Mercer, R. W. & Sznajder, J. I., Jan 1 1997, In : Annals of the New York Academy of Sciences. 834, p. 104-106 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Lung alveolar epithelial cells synthesize interstitial collagenase and gelatinases A and B in vitro

Pardo, A., Ridge, K., Uhal, B., Iasha Sznajder, J. & Selman, M., Jun 1 1997, In : International Journal of Biochemistry and Cell Biology. 29, 6, p. 901-910 10 p.

Research output: Contribution to journalArticle

31 Scopus citations
1998

Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase β1 subunit gene

Factor, P., Saldias, F., Ridge, K., Dumasius, V., Zabner, J., Jaffe, H. A., Blanco, G., Barnard, M., Mercer, R., Perrin, R. & Sznajder, J. I., Oct 1 1998, In : Journal of Clinical Investigation. 102, 7, p. 1421-1430 10 p.

Research output: Contribution to journalArticle

109 Scopus citations

Dopamine increases lung edema clearance in ventilator-associated lung injury in rats

Comellas, A. P., Saldias, F. J., Ridge, K. M. & Sznajder, J. I., Oct 1 1998, In : Chest. 114, 4 SUPPL.

Research output: Contribution to journalArticle

Epidermal growth factor increases lung liquid clearance in rat lungs

Sznajder, J. I., Ridge, K. M., Yeates, D. B., Ilekis, J. & Olivera, W., Sep 1 1998, In : Journal of applied physiology. 85, 3, p. 1004-1010 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Modulation of lung liquid clearance by isoproterenol in rat lungs

Saldías, F., Lecuona, E., Friedman, E., Barnard, M. L., Ridge, K. M. & Sznajder, J. I., May 1998, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 274, 5 18-5, p. L694-L701

Research output: Contribution to journalArticle

73 Scopus citations

Overexpression of the Na+,K+-ATPase α1 subunit increases Na+,K+-ATPase function in A549 cells

Factor, P., Senne, C., Dumasius, V., Ridge, K., Jaffe, H. A., Uhal, B., Gao, Z. & Sznajder, J. I., Jan 1 1998, In : American journal of respiratory cell and molecular biology. 18, 6, p. 741-749 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Time course of active and passive liquid and solute movement in the isolated perfused rat lung model

Saldías, F. J., Comellas, A., Guerrero, C., Ridge, K. M., Rutschman, D. H. & Sznajder, J. I., Oct 1 1998, In : Journal of applied physiology. 85, 4, p. 1572-1577 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
1999

Dopamine regulates NA,K-adenosine triphosphatase in alveolar epithelial cells via the mitogen-activated protein kinase/extracellular-signal-regulated kinase pathway

Guerrero, C., Ghosh, A., Lecuona, E., Ridge, K., Santos, E. & Sznajder, J. I., Jan 1 1999, In : CHEST. 116, SUPPL., p. 88S-89S

Research output: Contribution to journalArticle

5 Scopus citations

Dopamine restores lung ability to clear edema in rats exposed to hyperoxia

Saldías, F. J., Lecuona, E., Comellas, A. P., Ridge, K. M. & Sznajder, J. I., Jan 1 1999, In : American journal of respiratory and critical care medicine. 159, 2, p. 626-633 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Isoproterenol improves ability of lung to clear edema in rats exposed to hyperoxia

Saldías, F. J., Comellas, A., Ridge, K. M., Lecuona, E. & Sznajder, J. I., Jul 1 1999, In : Journal of applied physiology. 87, 1, p. 30-35 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Isoproterenol increases Na+-K+-ATPase activity by membrane insertion of α-subunits in lung alveolar cells

Bertorello, A. M., Ridge, K. M., Chibalin, A. V., Katz, A. I. & Sznajder, J. I., Jan 1 1999, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 276, 1 20-1, p. L20-L27

Research output: Contribution to journalArticle

146 Scopus citations

Mechanical stretching of alveolar epithelial cells increases Na+-K+- ATPase activity

Waters, C. M., Ridge, K. M., Sunio, G., Venetsanou, K. & Sznajder, J. I., Aug 18 1999, In : Journal of applied physiology. 87, 2, p. 715-721 7 p.

Research output: Contribution to journalArticle

56 Scopus citations

Stimulation of the dopamine 1 receptor increases lung edema clearance

Barnard, M. L., Ridge, K. M., Saldias, F., Friedman, E., Gare, M., Guerrero, C., Lecuona, E., Bertorello, A. M., Katz, A. I. & Sznajder, J. I., Jan 1 1999, In : American journal of respiratory and critical care medicine. 160, 3, p. 982-986 5 p.

Research output: Contribution to journalArticle

55 Scopus citations

Ventilator-associated lung injury decreases lung ability to clear edema and downregulates alveolar epithelial cell Na,K-adenosine triphosphatase function

Lecuona, E., Saldías, F., Comellas, A., Ridge, K., Guerrero, C. & Sznajder, J. I., Jan 1 1999, In : Chest. 116, SUPPL., p. 29S-30S

Research output: Contribution to journalArticle

12 Scopus citations

Ventilator-associated lung injury decreases lung ability to clear edema in rats

Lecuona, E., Saldías, F., Comellas, A., Ridge, K., Guerrero, C. & Sznajder, J. I., Jan 1 1999, In : American journal of respiratory and critical care medicine. 159, 2, p. 603-609 7 p.

Research output: Contribution to journalArticle

93 Scopus citations
2000

Aldosterone regulates Na,K-ATPase and increases lung edema clearance in rats

Olivera, W. G., Ciccolella, D. E., Barquin, N., Ridge, K. M., Rutschman, D. H., Yeates, D. B. & Sznajder, J. I., Jan 1 2000, In : American journal of respiratory and critical care medicine. 161, 2 I, p. 567-573 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Continuous enteral nutrition attenuates pulmonary edema in rats exposed to 100% oxygen

Factor, P., Ridge, K., Alverdy, J. & Sznajder, J. I., Nov 20 2000, In : Journal of applied physiology. 89, 5, p. 1759-1765 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

β-Adrenergic stimulation restores rat lung ability to clear edema in ventilator-associated lung injury

Saldías, F. J., Lecuona, E., Comellas, A. P., Ridge, K. M., Rutschman, D. H. & Sznajder, J. I., Jan 1 2000, In : American journal of respiratory and critical care medicine. 162, 1, p. 282-287 6 p.

Research output: Contribution to journalArticle

93 Scopus citations

β-Agonists regulate Na,K-ATPase via novel MAPK/ERK and rapamycin-sensitive pathways

Pesce, L., Guerrero, C., Comellas, A., Ridge, K. M. & Sznajder, J. I., Dec 15 2000, In : FEBS Letters. 486, 3, p. 310-314 5 p.

Research output: Contribution to journalArticle

44 Scopus citations
2001

Alveolar fluid reabsorption is impaired by increased left atrial pressures in rats

Saldías, F. J., Azzam, Z. S., Ridge, K. M., Yeldandi, A., Rutschman, D. H., Schraufnagel, D. & Sznajder, J. I., Oct 1 2001, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 281, 3 25-3

Research output: Contribution to journalArticle

48 Scopus citations

Catecholamines increase lung edema clearance in rats with increased left atrial pressure

Azzam, Z. S., Saldias, F. J., Comellas, A., Ridge, K. M., Rutschman, D. H. & Sznajder, J. I., Mar 6 2001, In : Journal of applied physiology. 90, 3, p. 1088-1094 7 p.

Research output: Contribution to journalArticle

43 Scopus citations
54 Scopus citations

Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung

John, T. A., Vogel, S. M., Minshall, R. D., Ridge, K., Tiruppathi, C. & Malik, A. B., Jun 1 2001, In : Journal of Physiology. 533, 2, p. 547-559 13 p.

Research output: Contribution to journalArticle

75 Scopus citations
2002
29 Scopus citations

Dopamine-induced exocytosis of Na,K-ATPase is dependent on activation of protein kinase C-ε and -δ

Ridge, K. M., Dada, L., Lecuona, E., Bertorello, A. M., Katz, A. I., Mochly-Rosen, D. & Sznajder, J. I., Apr 25 2002, In : Molecular Biology of the Cell. 13, 4, p. 1381-1389 9 p.

Research output: Contribution to journalArticle

89 Scopus citations
2003

Alveolar type 1 cells express the α2 Na,K-ATPase, which contributes to lung liquid clearance

Ridge, K. M., Olivera, W. G., Saldias, F., Azzam, Z., Horowitz, S., Rutschman, D. H., Dumasius, V., Factor, P. & Sznajder, J. I., Mar 7 2003, In : Circulation research. 92, 4, p. 453-460 8 p.

Research output: Contribution to journalArticle

98 Scopus citations
212 Scopus citations

Na,K-ATPase Gene Transfer Increases Liquid Clearance during Ventilation-induced Lung Injury

Adir, Y., Factor, P., Dumasius, V., Ridge, K. M. & Sznajder, J. I., Dec 15 2003, In : American journal of respiratory and critical care medicine. 168, 12, p. 1445-1448 4 p.

Research output: Contribution to journalArticle

28 Scopus citations

Pulmonary lymphatics and edema accumulation after brief lung injury

Schraufnagel, D. E., Agaram, N. P., Faruqui, A., Jain, S., Jain, L., Ridge, K. M. & Sznajder, J. I., May 1 2003, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 284, 5 28-5

Research output: Contribution to journalArticle

20 Scopus citations

The GTP-binding protein RhoA mediates Na,K-ATpase exocytosis in alveolar epithelial cells

Lecuona, E., Ridge, K., Pesce, L., Batlle, D. & Sznajder, J. I., Sep 1 2003, In : Molecular biology of the cell. 14, 9, p. 3888-3897 10 p.

Research output: Contribution to journalArticle

38 Scopus citations
2004

Augmentation of Endogenous Dopamine Production Increases Lung Liquid Clearance

Adir, Y., Azzam, Z. S., Lecuona, E., Leal, S., Pesce, L., Dumasius, V., Bertorello, A. M., Factor, P., Young, J. B., Ridge, K. M. & Sznajder, J. I., Mar 15 2004, In : American Journal of Respiratory and Critical Care Medicine. 169, 6, p. 757-763 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Leukotriene D4 Activates Alveolar Epithelial Na,K-ATPase and Increases Alveolar Fluid Clearance

Sloniewsky, D. E., Ridge, K. M., Adir, Y., Fries, F. P., Briva, A., Sznajder, J. I. & Sporn, P. H. S., Feb 1 2004, In : American Journal of Respiratory and Critical Care Medicine. 169, 3, p. 407-412 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Norepinephrine increases alveolar fluid reabsorption and Na,K-ATPase activity

Azzam, Z. S., Adir, Y., Crespo, A., Comellas, A., Lecuona, E., Dada, L. A., Krivoy, N., Rutschman, D. H., Sznajder, J. I. & Ridge, K. M., Oct 1 2004, In : American Journal of Respiratory and Critical Care Medicine. 170, 7, p. 730-736 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
2005

Hypocapnic but not metabolic alkalosis impairs alveolar fluid reabsorption

Myrianthefs, P. M., Briva, A., Lecuona, E., Dumasius, V., Rutschman, D. H., Ridge, K. M., Baltopoulos, G. J. & Sznajder, J. I., Jun 1 2005, In : American journal of respiratory and critical care medicine. 171, 11, p. 1267-1271 5 p.

Research output: Contribution to journalArticle

20 Scopus citations