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Research Output

Article
90 Scopus citations

Aldosterone regulates Na,K-ATPase and increases lung edema clearance in rats

Olivera, W. G., Ciccolella, D. E., Barquin, N., Ridge, K. M., Rutschman, D. H., Yeates, D. B. & Sznajder, J. I., Jan 1 2000, In : American journal of respiratory and critical care medicine. 161, 2 I, p. 567-573 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Alpha-2 Na,K-ATPase contributes to lung liquid clearance

Ridge, K., Olivera, W., Rutschman, D. H., Mercer, R. W., Uhal, B., Horowitz, S., Hughes, F., Factor, P., Barnard, M. L. & Sznajder, J. I., Jan 1 1997, In : Annals of the New York Academy of Sciences. 834, p. 651-652 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Alveolar fluid reabsorption is impaired by increased left atrial pressures in rats

Saldías, F. J., Azzam, Z. S., Ridge, K. M., Yeldandi, A., Rutschman, D. H., Schraufnagel, D. & Sznajder, J. I., Oct 1 2001, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 281, 3 25-3

Research output: Contribution to journalArticle

48 Scopus citations

Alveolar type 1 cells express the α2 Na,K-ATPase, which contributes to lung liquid clearance

Ridge, K. M., Olivera, W. G., Saldias, F., Azzam, Z., Horowitz, S., Rutschman, D. H., Dumasius, V., Factor, P. & Sznajder, J. I., Mar 7 2003, In : Circulation research. 92, 4, p. 453-460 8 p.

Research output: Contribution to journalArticle

98 Scopus citations

Alveolar type II cell Na,K-ATPase is upregulated during mechanical ventilation-induced pulmonary edema

Sznajder, J. I., Ridge, K. M., Harris, Z. L., Olivera, W., Curiet, C., Venezuely, C. & Rutschman, D. H., Jan 1 1994, In : CHEST. 105, 3 SUPPL., p. 116S-117S

Research output: Contribution to journalArticle

11 Scopus citations

ANF decreases active sodium transport and increases alveolar epithelial permeability in rats

Olivera, W., Ridge, K., Wood, L. D. H. & Sznajder, J. I., Jan 1 1993, In : Journal of Applied Physiology. 75, 4, p. 1581-1586 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Asbestos-induced alveolar epithelial cell apoptosis: The role of endoplasmic reticulum stress response

Kamp, D. W., Liu, G., Cheresh, P., Kim, S. J., Mueller, A., Lam, A. P., Trejo, H., Williams, D., Tulasiram, S., Baker, M., Ridge, K., Chandel, N. S. & Beri, R., Dec 1 2013, In : American journal of respiratory cell and molecular biology. 49, 6, p. 892-901 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice

Cheresh, P., Morales-Nebreda, L., Kim, S. J., Yeldandi, A., Williams, D. B., Cheng, Y., Mutlu, G. M., Scott Budinger, G. R., Ridge, K., Schumacker, P. T., Bohr, V. A. & Kamp, D. W., Jan 1 2015, In : American journal of respiratory cell and molecular biology. 52, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Augmentation of Endogenous Dopamine Production Increases Lung Liquid Clearance

Adir, Y., Azzam, Z. S., Lecuona, E., Leal, S., Pesce, L., Dumasius, V., Bertorello, A. M., Factor, P., Young, J. B., Ridge, K. M. & Sznajder, J. I., Mar 15 2004, In : American Journal of Respiratory and Critical Care Medicine. 169, 6, p. 757-763 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase β1 subunit gene

Factor, P., Saldias, F., Ridge, K., Dumasius, V., Zabner, J., Jaffe, H. A., Blanco, G., Barnard, M., Mercer, R., Perrin, R. & Sznajder, J. I., Oct 1 1998, In : Journal of Clinical Investigation. 102, 7, p. 1421-1430 10 p.

Research output: Contribution to journalArticle

109 Scopus citations

Catecholamines increase lung edema clearance in rats with increased left atrial pressure

Azzam, Z. S., Saldias, F. J., Comellas, A., Ridge, K. M., Rutschman, D. H. & Sznajder, J. I., Mar 6 2001, In : Journal of applied physiology. 90, 3, p. 1088-1094 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Continuous enteral nutrition attenuates pulmonary edema in rats exposed to 100% oxygen

Factor, P., Ridge, K., Alverdy, J. & Sznajder, J. I., Nov 20 2000, In : Journal of applied physiology. 89, 5, p. 1759-1765 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Dexamethasone upregulates the Na-K-ATPase in rat alveolar epithelial cells

Barquin, N., Ciccolella, D. E., Ridge, K. M. & Sznajder, J. I., Jan 1 1997, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 273, 4 17-4, p. L825-L830

Research output: Contribution to journalArticle

62 Scopus citations

Differential binding of plasminogen, plasmin, and Angiostatin4.5 to cell surface β-actin: Implications for cancer-mediated angiogenesis

Wang, H., Doll, J. A., Jiang, K., Cundiff, D. L., Czarnecki, J. S., Wilson, M., Ridge, K. M. & Soff, G. A., Jul 15 2006, In : Cancer Research. 66, 14, p. 7211-7215 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Differential effects of adenoviral-mediated transfer of Na+/K+-ATPase subunit genes in lung epithelial cells

Factor, P., Senne, C., Ridge, K., Jaffe, H. A. & Sznajder, J. I., Jan 1 1997, In : Chest. 111, 6 SUPPL., p. 110S-111S

Research output: Contribution to journalArticle

2 Scopus citations

Differential expression of Na-K-ATPase isoforms in rat alveolar epithelial cells

Ridge, K. M., Rutschman, D. H., Factor, P., Katz, A. I., Bertorello, A. M. & Sznajder, J. I., Jul 1 1997, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 273, 1 17-1, p. L246-L255

Research output: Contribution to journalArticle

82 Scopus citations
29 Scopus citations

Dopamine increases active na+ transport and lung liquid clearance

Barnard, M. L., Ridge, K. M., Qlivara, W. G., Rirtschman, D. H., Ashwath-Naravan, R. & Sznaider, J. I., Dec 1 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

2 Scopus citations

Dopamine increases lung edema clearance in ventilator-associated lung injury in rats

Comellas, A. P., Saldias, F. J., Ridge, K. M. & Sznajder, J. I., Oct 1 1998, In : Chest. 114, 4 SUPPL.

Research output: Contribution to journalArticle

Dopamine-induced exocytosis of Na,K-ATPase is dependent on activation of protein kinase C-ε and -δ

Ridge, K. M., Dada, L., Lecuona, E., Bertorello, A. M., Katz, A. I., Mochly-Rosen, D. & Sznajder, J. I., Apr 25 2002, In : Molecular biology of the cell. 13, 4, p. 1381-1389 9 p.

Research output: Contribution to journalArticle

89 Scopus citations

Dopamine regulates NA,K-adenosine triphosphatase in alveolar epithelial cells via the mitogen-activated protein kinase/extracellular-signal-regulated kinase pathway

Guerrero, C., Ghosh, A., Lecuona, E., Ridge, K., Santos, E. & Sznajder, J. I., Jan 1 1999, In : CHEST. 116, SUPPL., p. 88S-89S

Research output: Contribution to journalArticle

5 Scopus citations
54 Scopus citations

Dopamine restores lung ability to clear edema in rats exposed to hyperoxia

Saldías, F. J., Lecuona, E., Comellas, A. P., Ridge, K. M. & Sznajder, J. I., Jan 1 1999, In : American journal of respiratory and critical care medicine. 159, 2, p. 626-633 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Effects of adenoviral mediated transfer of Na+,K+-ATPase subunit genes to alveolar epithelial cells

Factor, P., Senne, C., Ridge, K., Jaffe, H. A., Blanco, G., Mercer, R. W. & Sznajder, J. I., Jan 1 1997, In : Annals of the New York Academy of Sciences. 834, p. 104-106 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Epidermal growth factor increases lung liquid clearance in rat lungs

Sznajder, J. I., Ridge, K. M., Yeates, D. B., Ilekis, J. & Olivera, W., Sep 1 1998, In : Journal of applied physiology. 85, 3, p. 1004-1010 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung

John, T. A., Vogel, S. M., Minshall, R. D., Ridge, K., Tiruppathi, C. & Malik, A. B., Jun 1 2001, In : Journal of Physiology. 533, 2, p. 547-559 13 p.

Research output: Contribution to journalArticle

76 Scopus citations

Future research directions in pneumonia

Dela Cruz, C. S., Wunderink, R. G., Christiani, D. C., Cormier, S. A., Crothers, K., Doerschuk, C. M., Evans, S. E., Goldstein, D. R., Khatri, P., Kobzik, L., Kolls, J. K., Levy, B. D., Metersky, M. L., Niederman, M. S., Nusrat, R., Orihuela, C. J., Peyrani, P., Prince, A. S., Ramírez, J. A., Ridge, K. M. & 9 others, Sethi, S., Suratt, B. T., Sznajder, J. I., Tsalik, E. L., Walkey, A. J., Yende, S., Aggarwal, N. R., Caler, E. V. & Mizgerd, J. P., Jul 15 2018, In : American journal of respiratory and critical care medicine. 198, 2, p. 256-263 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

FXYD5 is an essential mediator of the inflammatory response during lung injury

Brazee, P. L., Soni, P. N., Tokhtaeva, E., Magnani, N., Yemelyanov, A., Perlman, H. R., Ridge, K. M., Sznajder, J. I., Vagin, O. & Dada, L. A., Jun 1 2017, In : Frontiers in immunology. 8, JUN, 623.

Research output: Contribution to journalArticle

8 Scopus citations

Hydrogen peroxide increases Na+/K+-ATPase function in alveolar type II cells

González-Flecha, B., Evelson, P., Ridge, K. & Sznajder, J. I., May 21 1996, In : Biochimica et Biophysica Acta - General Subjects. 1290, 1, p. 46-52 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Hyperbaric oxygenation upregulates rat lung Na,K-ATPase

Harris, Z. L., Ridge, K. M., Gonzalez-Flecha, B., Gottlieb, L., Zucker, A. & Sznajder, J. I., Mar 1 1996, In : European Respiratory Journal. 9, 3, p. 472-477 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Hypocapnic but not metabolic alkalosis impairs alveolar fluid reabsorption

Myrianthefs, P. M., Briva, A., Lecuona, E., Dumasius, V., Rutschman, D. H., Ridge, K. M., Baltopoulos, G. J. & Sznajder, J. I., Jun 1 2005, In : American journal of respiratory and critical care medicine. 171, 11, p. 1267-1271 5 p.

Research output: Contribution to journalArticle

20 Scopus citations
214 Scopus citations

Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling

Weisel, F. C., Kloepping, C., Pichl, A., Sydykov, A., Kojonazarov, B., Wilhelm, J., Roth, M., Ridge, K. M., Igarashi, K., Nishimura, K., Maison, W., Wackendorff, C., Klepetko, W., Jaksch, P., Ghofrani, H. A., Grimminger, F., Seeger, W., Schermuly, R. T., Weissmann, N. & Kwapiszewska, G., Apr 8 2014, In : Circulation. 129, 14, p. 1510-1523 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Increased expression of gelatinases and collagenase in rat lungs exposed to 100% oxygen

Pardo, A., Selman, M., Ridge, K., Barrios, R. & Sznajder, J. I., Jan 1 1996, In : American journal of respiratory and critical care medicine. 154, 4 I, p. 1067-1075 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

Inflammatory monocytes drive influenza A virus-mediated lung injury in juvenile mice

Coates, B. M., Staricha, K. L., Koch, C. M., Cheng, Y., Shumaker, D. K., Budinger, G. R. S., Perlman, H., Misharin, A. V. & Ridge, K. M., Apr 1 2018, In : Journal of Immunology. 200, 7, p. 2391-2404 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Inflammatory pathways are upregulated in the nasal epithelium in patients with idiopathic pulmonary fibrosis

Sala, M. A., Balderas-Martínez, Y. I., Buendía-Roldan, I., Abdala-Valencia, H., Nam, K., Jain, M., Bhorade, S., Bharat, A., Reyfman, P. A., Ridge, K. M., Pardo, A., Sznajder, J. I., Budinger, G. R. S., Misharin, A. V. & Selman, M., Nov 26 2018, In : Respiratory Research. 19, 1, 233.

Research output: Contribution to journalArticle

Influenza virus-induced lung injury: Pathogenesis and implications for treatment

Herold, S., Becker, C., Ridge, K. M. & Budinger, G. R. S., May 1 2015, In : European Respiratory Journal. 45, 5, p. 1463-1478 16 p.

Research output: Contribution to journalArticle

78 Scopus citations

Inhibition of the NOD-like receptor protein 3 inflammasome is protective in juvenile influenza a virus infection

Coates, B. M., Staricha, K. L., Ravindran, N., Koch, C. M., Cheng, Y., Davis, J. M., Shumaker, D. K. & Ridge, K. M., Jul 10 2017, In : Frontiers in immunology. 8, JUL, 782.

Research output: Contribution to journalArticle

22 Scopus citations

Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury

Morales-Nebreda, L., Chi, M., Lecuona, E., Chandel, N. S., Dada, L. A., Ridge, K., Soberanes, S., Nigdelioglu, R., Sznajder, J. I., Mutlu, G. M., Budinger, G. R. S. & Radigan, K. A., Dec 1 2014, In : Journal of Virological Methods. 209, p. 116-120 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Isoproterenol improves ability of lung to clear edema in rats exposed to hyperoxia

Saldías, F. J., Comellas, A., Ridge, K. M., Lecuona, E. & Sznajder, J. I., Jul 1 1999, In : Journal of applied physiology. 87, 1, p. 30-35 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Isoproterenol increases Na+-K+-ATPase activity by membrane insertion of α-subunits in lung alveolar cells

Bertorello, A. M., Ridge, K. M., Chibalin, A. V., Katz, A. I. & Sznajder, J. I., Jan 1 1999, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 276, 1 20-1, p. L20-L27

Research output: Contribution to journalArticle

147 Scopus citations
99 Scopus citations
14 Scopus citations

Laminin-311 (laminin-6) fiber assembly by type I-like alveolar cells

DeBiase, P. J., Lane, K., Budinger, S., Ridge, K., Wilson, M. & Jones, J. C. R., Jun 1 2006, In : Journal of Histochemistry and Cytochemistry. 54, 6, p. 665-672 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Leukotriene D4 Activates Alveolar Epithelial Na,K-ATPase and Increases Alveolar Fluid Clearance

Sloniewsky, D. E., Ridge, K. M., Adir, Y., Fries, F. P., Briva, A., Sznajder, J. I. & Sporn, P. H. S., Feb 1 2004, In : American Journal of Respiratory and Critical Care Medicine. 169, 3, p. 407-412 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Lung alveolar epithelial cells synthesize interstitial collagenase and gelatinases A and B in vitro

Pardo, A., Ridge, K., Uhal, B., Iasha Sznajder, J. & Selman, M., Jun 1 1997, In : International Journal of Biochemistry and Cell Biology. 29, 6, p. 901-910 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Lung liquid clearance and NA,K-ATPase during acute hyperoxia and recovery in rats

Olivera, W. G., Ridge, K. M. & Sznajder, J. I., Jan 1 1995, In : American Journal of Respiratory and Critical Care Medicine. 152, 4 I, p. 1229-1234 6 p.

Research output: Contribution to journalArticle

101 Scopus citations

Lung-specific loss of a3 laminin worsens bleomycin-induced pulmonary fibrosis

Morales-Nebreda, L. I., Rogel, M. R., Eisenberg, J. L., Hamill, K. J., Soberanes, S., Nigdelioglu, R., Chi, M., Cho, T., Radigan, K. A., Ridge, K. M., Misharin, A. V., Woychek, A., Hopkinson, S., Perlman, H., Mutlu, G. M., Pardo, A., Selman, M., Jones, J. C. R. & Scott Budinger, G. R., Apr 1 2015, In : American journal of respiratory cell and molecular biology. 52, 4, p. 503-512 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mechanical stretching of alveolar epithelial cells increases Na+-K+- ATPase activity

Waters, C. M., Ridge, K. M., Sunio, G., Venetsanou, K. & Sznajder, J. I., Aug 18 1999, In : Journal of applied physiology. 87, 2, p. 715-721 7 p.

Research output: Contribution to journalArticle

56 Scopus citations