Grants per year
Personal profile
Research Interests
Professor Scheidt’s research group is a collaborative and interdisciplinary program at the forefront of the discovery of new catalytic reactions and their application in medicine and energy. Specifically, they have pioneered the use of small organic molecules as catalysts in a multitude of high value chemical transformations. These processes provide new avenues for molecular construction and offer sustainable advantages to established transition metal catalyzed approaches. In the realm of therapeutic translational science, they are creating new routes to natural products and related analogs with promising activities against cancer and central nervous system disorders.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Organic Chemistry, PhD, Indiana University Bloomington
… → 1999
Chemistry, BS, University of Notre Dame
… → 1994
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Dive into the research topics where Karl A Scheidt is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Bioinspired chemical probe approach targeting telomerase reverse transcriptase
9/1/20 → 5/31/25
Project: Research project
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New Cooperative Catalysis Concepts for Asymmetric Synthesis
National Institute of General Medical Sciences
6/1/20 → 5/31/25
Project: Research project
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New Acid Catalysis Concepts for Asymmetric Synthesis
National Institute of General Medical Sciences
9/1/19 → 8/31/20
Project: Research project
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The Robert H. Lurie Comprehensive Cancer Center
Platanias, L. C., Arispe, L., Arvanitis, C., Bonini, M., Butt, Z., Kocherginsky, M., Kumthekar, P. U., Rini, C., Shilatifard, A., Wignall, S., Zhang, Z., Agulnik, M., Awatramani, R., Backman, V., Benson III, A. B., Carthew, R. W., Cella, D., Chakravarti, D., Chandel, N., Crispino, J. D., Cristofanilli, M., Eklund, E. A., Frankfurt, O., Gordon, L. I., Green, K. J., Hahn, E. A., Hitsman, B. L., Horbinski, C. M., Horvath, C. M., Hussain, M., James, C. D., Kelleher, N. L., Khan, S. A., LaBonne, C., Larson, A. C., Matei, D. E., Meade, T. J., Mondragon, A., Mrksich, M., Munshi, H. G., Murphy, A. B., Obeng, R., Penedo, F. J., Perlman, H. R., Peter, M. E., Rademaker, A. W., Rappoport, J. Z., Rosenzweig, A. C., Scheidt, K. A., Simon, M. A., Sosman, J. A., Spring, B., Wei, J., Weiss, E. L. & Woloschak, G. E.
8/10/18 → 7/31/23
Project: Research project
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RHLCCC: Medicinal & Synthetic Chemistry Core
Mishra, R. K., Schiltz, G. E. & Scheidt, K. A.
8/1/16 → 7/31/18
Project: Research project
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Acyl Azolium-Photoredox-Enabled Synthesis of β-Keto Sulfides
Rourke, M. J., Wang, C. T., Schull, C. R. & Scheidt, K. A., 2023, (Accepted/In press) In: ACS Catalysis. p. 7987-7994 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia
Rajagopal, L., Mahjour, S., Huang, M., Ryan, C. A., Elzokaky, A., Csakai, A. J., Orr, M. J., Scheidt, K. & Meltzer, H. Y., Oct 2 2023, In: Behavioural Brain Research. 454, 114614.Research output: Contribution to journal › Article › peer-review
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Photocatalyzed Direct α-Alkylation of Esters Using Styrenes
Wang, P., Bay, A. V., Farnam, E. J. & Scheidt, K. A., Jul 18 2023, In: Advanced Synthesis and Catalysis. 365, 14, p. 2361-2366 6 p.Research output: Contribution to journal › Article › peer-review
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Photoinduced Acylations Via Azolium-Promoted Intermolecular Hydrogen Atom Transfer
Zhu, J. L., Schull, C. R., Tam, A. T., Rentería-Gómez, Á., Gogoi, A. R., Gutierrez, O. & Scheidt, K. A., Jan 25 2023, In: Journal of the American Chemical Society. 145, 3, p. 1535-1541 7 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Photoredox-Catalyzed Radical-Radical Coupling of Potassium Trifluoroborates with Acyl Azoliums
Rourke, M. J., McGill, M. J., Yang, D., Farnam, E. J., Zhu, J. L. & Scheidt, K. A., 2023, (Accepted/In press) In: Synlett.Research output: Contribution to journal › Article › peer-review
Datasets
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CCDC 780030: Experimental Crystal Structure Determination
Brekan, J. A. (Creator), Reynolds, T. E. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2010
DOI: 10.5517/ccv5p8y, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccv5p8y&sid=DataCite
Dataset
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CCDC 1412859: Experimental Crystal Structure Determination
Hall, E. A. (Creator), Redfern, L. R. (Creator), Wang, M. H. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2016
DOI: 10.5517/ccdc.csd.cc1jf638, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1jf638&sid=DataCite
Dataset
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CCDC 1835355: Experimental Crystal Structure Determination
McDonald, B. R. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1zlv0f, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zlv0f&sid=DataCite
Dataset
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CCDC 969569: Experimental Crystal Structure Determination
Zeng, B. (Creator), Yu, X. (Creator), Siu, P. W. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cc11jxfx, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc11jxfx&sid=DataCite
Dataset
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CCDC 688527: Experimental Crystal Structure Determination
Reynolds, T. E. (Creator), Binkley, M. S. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2009
DOI: 10.5517/ccr3gkv, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccr3gkv&sid=DataCite
Dataset