Grants per year
Personal profile
Research Interests
Professor Scheidt’s research group is a collaborative and interdisciplinary program at the forefront of the discovery of new catalytic reactions and their application in medicine and energy. Specifically, they have pioneered the use of small organic molecules as catalysts in a multitude of high value chemical transformations. These processes provide new avenues for molecular construction and offer sustainable advantages to established transition metal catalyzed approaches. In the realm of therapeutic translational science, they are creating new routes to natural products and related analogs with promising activities against cancer and central nervous system disorders.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Organic Chemistry, PhD, Indiana University Bloomington
… → 1999
Chemistry, BS, University of Notre Dame
… → 1994
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Collaborations and top research areas from the last five years
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A Molecular Approach to Dissecting MEK-Mediated Phosphorylation in Pediatric Leukemia
Scheidt, K. A. (PD/PI), Schiltz, G. E. (PD/PI) & Zhang, X. (Co-Investigator)
5/15/24 → 4/30/29
Project: Research project
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PAIRS: Validating telomerase reverse transcriptase (TERT) as an intrinsic vulnerability toward sensitizing cancer to radiation
Scheidt, K. A. (PD/PI)
The University of Chicago, National Cancer Institute
7/1/23 → 6/30/28
Project: Research project
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CCI Phase I: NSF Center for Chemoenzymatic Synthesis
Scheidt, K. A. (PD/PI)
9/1/22 → 8/31/25
Project: Research project
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Targeting ATG4B to Treat Glioblastoma
Scheidt, K. A. (PD/PI) & Scheidt, K. A. (PD/PI)
National Institute of Neurological Disorders and Stroke
4/15/22 → 9/30/25
Project: Research project
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Bioinspired chemical probe approach targeting telomerase reverse transcriptase
Scheidt, K. A. (PD/PI) & Scheidt, K. A. (PD/PI)
9/1/20 → 5/31/25
Project: Research project
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C(sp3)-H Carboxylation via Carbene/Photoredox Cooperative Catalysis
Schull, C. R., Cao, J., Mitton-Fry, S. R., Mrksich, M. & Scheidt, K. A., Jan 17 2025, In: ACS Catalysis. 15, 2, p. 1287-1293 7 p.Research output: Contribution to journal › Article › peer-review
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Discovery of DCAF16 Binders for Targeted Protein Degradation
Campos, M. A., Riha, I. A., Zhang, C., Mozes, C., Scheidt, K. A. & Zhang, X., Feb 21 2025, In: ACS chemical biology. 20, 2, p. 479-488 10 p.Research output: Contribution to journal › Article › peer-review
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Dual NHC/HAT-Promoted Esterification to Access α-Aryl Glycines
McGill, M. J., Wayment, A. X., Schull, C. R. & Scheidt, K. A., Jan 21 2025, In: Advanced Synthesis and Catalysis. 367, 2, e202401207.Research output: Contribution to journal › Article › peer-review
Open Access -
A Platform for the Synthesis of Corynantheine-Type Corynanthe Alkaloids
Nam, Y., Tam, A. T., Miller, E. R. & Scheidt, K. A., Jan 10 2024, In: Journal of the American Chemical Society. 146, 1, p. 118-124 7 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Combined Photocatalysis and Lewis Acid Catalysis Strategy for the Oxa-Pictet-Spengler Reactions of Ethers
Tanaka, N., Mitton-Fry, S. R., Hwang, M. U., Zhu, J. L. & Scheidt, K. A., May 17 2024, In: ACS Catalysis. 14, 10, p. 7949-7955 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Datasets
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CCDC 1900654: Experimental Crystal Structure Determination
Squitieri, R. A. (Contributor), Fitzpatrick, K. P. (Contributor), Jaworski, A. A. (Contributor) & Scheidt, K. A. (Contributor), Cambridge Crystallographic Data Centre, 2019
DOI: 10.5517/ccdc.csd.cc21ssf2, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc21ssf2&sid=DataCite
Dataset
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CCDC 2252362: Experimental Crystal Structure Determination
Nam, Y. (Contributor), Tam, A. T. (Contributor), Miller, E. R. (Contributor) & Scheidt, K. A. (Contributor), Cambridge Crystallographic Data Centre, 2023
DOI: 10.5517/ccdc.csd.cc2flrvn, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2flrvn&sid=DataCite
Dataset
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CCDC 606454: Experimental Crystal Structure Determination
Chan, A. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2006
DOI: 10.5517/ccnc213, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccnc213&sid=DataCite
Dataset
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CCDC 956375: Experimental Crystal Structure Determination
McCusker, E. O. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cc1135t4, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc1135t4&sid=DataCite
Dataset
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CCDC 869606: Experimental Crystal Structure Determination
Dugal-Tessier, J. (Creator), O'Bryan, E. A. (Creator), Schroeder, T. B. H. (Creator), Cohen, D. T. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2013
DOI: 10.5517/ccy5wts, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccy5wts&sid=DataCite
Dataset