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Research Output 1993 2019

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2019
1 Citation (Scopus)

Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter

Zhu, Y., Zou, X., Dean, A. E., Brien, J. O., Gao, Y., Tran, E. L., Park, S. H., Liu, G., Kieffer, M. B., Jiang, H., Stauffer, M. E., Hart, R., Quan, S., Satchell, K. J. F., Horikoshi, N., Bonini, M. & Gius, D. R., Dec 1 2019, In : Nature communications. 10, 1, 2399.

Research output: Contribution to journalArticle

Open Access
acetylation
Acetylation
Detoxification
inorganic peroxides
lysine
1 Citation (Scopus)

RRSP and RID effector domains dominate the virulence impact of vibrio vulnificus MARTX toxin

Gavin, H. E. & Satchell, K. J. F., Feb 23 2019, In : Journal of Infectious Diseases. 219, 6, p. 889-897 9 p.

Research output: Contribution to journalArticle

Vibrio vulnificus
Virulence
Infection
Phagocytosis
ras Proteins
4-Hydroxybenzoate-3-Monooxygenase
Oxygenases
Pseudomonas putida
pseudomonas
adenines
2018
4 Citations (Scopus)

Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43

Kam, C. Y., Dubash, A. D., Magistrati, E., Polo, S., Satchell, K. J. F., Sheikh, F., Lampe, P. D. & Green, K. J., Sep 1 2018, In : Journal of Cell Biology. 217, 9, p. 3219-3235 17 p.

Research output: Contribution to journalArticle

Desmoplakins
Connexin 43
Gap Junctions
Cardiomyopathies
RNA Sequence Analysis
1 Citation (Scopus)

Draft genome sequences of two Vibrio parahaemolyticus strains associated with gastroenteritis after raw seafood ingestion in Colorado

Trinh, S. A., Leyn, S. A., Rodionov, I. D., Godzik, A. & Satchell, K. J. F., Jan 1 2018, In : Genome Announcements. 6, 3, e01387-17.

Research output: Contribution to journalArticle

Vibrio parahaemolyticus
Seafood
Gastroenteritis
Centers for Disease Control and Prevention (U.S.)
Eating
2 Citations (Scopus)

The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling

Biancucci, M., Minasov, G., Banerjee, A., Herrera, A., Woida, P. J., Kieffer, M. B., Bindu, L., Abreu-Blanco, M., Anderson, W. F., Gaponenko, V., Stephen, A. G., Holderfield, M. & Satchell, K. J. F., Oct 2 2018, In : Science Signaling. 11, 550, eaat8335.

Research output: Contribution to journalArticle

Endopeptidases
Nucleotides
Pathogens
Peptide Hydrolases
Vibrio vulnificus
1 Citation (Scopus)

Vibrio2017: The Seventh International Conference on the Biology of Vibrios

Klose, K. E. & Satchell, K. J. F., Aug 1 2018, In : Journal of bacteriology. 200, 15, e00304-18.

Research output: Contribution to journalArticle

Vibrio
Coral Reefs
Shellfish
Fishes
Water
2017
5 Citations (Scopus)
Vibrio vulnificus
Ceftriaxone
Doxycycline
Ciprofloxacin
Sepsis
2 Citations (Scopus)

New ligation independent cloning vectors for expression of recombinant proteins with a self-cleaving CPD/6xHis-tag

Biancucci, M., Dolores, J. S., Wong, J., Grimshaw, S., Anderson, W. F., Satchell, K. J. F. & Kwon, K., Jan 5 2017, In : BMC Biotechnology. 17, 1, 1.

Research output: Contribution to journalArticle

Genetic Vectors
Cysteine Proteases
Recombinant Proteins
Ligation
Solubility
8 Citations (Scopus)

Substrate Recognition of MARTX Ras/Rap1-Specific Endopeptidase

Biancucci, M., Rabideau, A. E., Lu, Z., Loftis, A. R., Pentelute, B. L. & Satchell, K. J. F., May 30 2017, In : Biochemistry. 56, 21, p. 2747-2757 11 p.

Research output: Contribution to journalArticle

Endopeptidases
Substrates
Switches
GTP Phosphohydrolases
Substrate Specificity
5 Citations (Scopus)

Surface hypothermia predicts murine mortality in the intragastric Vibrio vulnificus infection model

Gavin, H. E. & Satchell, K. J. F., Jun 19 2017, In : BMC Microbiology. 17, 1, 136.

Research output: Contribution to journalArticle

Hypothermia
Vibrio vulnificus
Temperature
Mortality
Virulence
15 Citations (Scopus)
Vibrio vulnificus
Intestines
Virulence
Necrosis
Pathology
5 Citations (Scopus)

Variable virulence of biotype 3 Vibrio vulnificus due to MARTX toxin effector domain composition

Kim, B. S., Gavin, H. E. & Satchell, K. J. F., Jul 1 2017, In : mSphere. 2, 4, e00272-17.

Research output: Contribution to journalArticle

Vibrio vulnificus
Virulence
Disease Outbreaks
Tilapia
Food Chain
2016
5 Citations (Scopus)

MARTX effector cross kingdom activation by Golgi-associated ADP-ribosylation factors

Kim, B. S. & Satchell, K. J. F., Aug 1 2016, In : Cellular Microbiology. 18, 8, p. 1078-1093 16 p.

Research output: Contribution to journalArticle

ADP-Ribosylation Factors
Vibrio vulnificus
Cysteine
Vibrio
Virulence Factors
17 Citations (Scopus)

Phenotypic analysis reveals that the 2010 haiti cholera epidemic is linked to a hypervirulent strain

Satchell, K. J. F., Jones, C. J., Wong, J., Queen, J., Agarwal, S. & Yildiz, F. H., Jan 1 2016, In : Infection and immunity. 84, 9, p. 2473-2481 9 p.

Research output: Contribution to journalArticle

Haiti
Cholera
Virulence
Cholera Toxin
Vibrio cholerae O1
7 Citations (Scopus)

SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status

Song, H. Y., Biancucci, M., Kang, H. J., O'Callaghan, C., Park, S. H., Principe, D. R., Jiang, H., Yan, Y., Satchell, K. F., Raparia, K., Gius, D. & Vassilopoulos, A., Jan 1 2016, In : Oncotarget. 7, 49, p. 80336-80349 14 p.

Research output: Contribution to journalArticle

Acetylation
Carcinogenesis
Phenotype
Post Translational Protein Processing
Mass Spectrometry
2015
12 Citations (Scopus)

A novel phosphatidylinositol 4,5-bisphosphate binding domain mediates plasma membrane localization of ExoU and other patatin-like phospholipases

Tyson, G. H., Halavaty, A. S., Kim, H., Geissler, B., Agard, M., Satchell, K. J. F., Cho, W., Anderson, W. F. & Hauser, A. R., Jan 30 2015, In : Journal of Biological Chemistry. 290, 5, p. 2919-2937 19 p.

Research output: Contribution to journalArticle

Phospholipases
Cell membranes
Phosphatidylinositols
Cell Membrane
Membranes
18 Citations (Scopus)

Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol-3-phosphate-specific phospholipase A1 activity

Agarwal, S., Kim, H., Chan, R. B., Agarwal, S., Williamson, R., Cho, W., Paolo, G. D. & Satchell, K. J. F., Oct 26 2015, In : Nature communications. 6, 8745.

Research output: Contribution to journalArticle

Phospholipases A1
cholera
Autophagy
Hydrolases
phosphates
26 Citations (Scopus)
Vibrio vulnificus
Terminal Repeat Sequences
Seafood
Cysteine Proteases
Virulence Factors
1 Citation (Scopus)
Vibrio vulnificus
Genotype
Genome
Ostreidae
Wound Infection
12 Citations (Scopus)

Induced autoprocessing of the cytopathic Makes caterpillars floppy-like effector domain of the Vibrio vulnificusMARTX toxin

Agarwal, S., Agarwal, S., Biancucci, M. & Satchell, K. J. F., Oct 1 2015, In : Cellular Microbiology. 17, 10, p. 1494-1509 16 p.

Research output: Contribution to journalArticle

Vibrio
Cysteine Proteases
Catalytic Domain
Vibrio vulnificus
Pseudomonas syringae
4 Citations (Scopus)

Mechanisms of inflammasome activation by Vibrio cholerae secreted toxins vary with strain biotype

Queen, J., Agarwal, S., Dolores, J. S., Stehlik, C. & Satchell, K. J. F., Jan 1 2015, In : Infection and Immunity. 83, 6, p. 2496-2506 11 p.

Research output: Contribution to journalArticle

Inflammasomes
Vibrio cholerae
Cholera Toxin
Interleukin-1
Hemolysin Proteins
31 Citations (Scopus)

Multifunctional-autoprocessing repeats-in-toxin (MARTX) toxins of Vibrios

Satchell, K. J. F., Jan 1 2015, In : Microbiology spectrum. 3, 3, VE-0002-2014.

Research output: Contribution to journalArticle

Vibrio
toxin
Biological Phenomena
Homologous Recombination
Eukaryotic Cells
23 Citations (Scopus)

Site-specific processing of Ras and Rap1 Switch i by a MARTX toxin effector domain

Antic, I., Biancucci, M., Zhu, Y., Gius, D. R. & Satchell, K. J. F., Jun 8 2015, In : Nature communications. 6, 7396.

Research output: Contribution to journalArticle

effectors
Sarcoma
rats
Rats
switches
12 Citations (Scopus)

The Makes Caterpillars Floppy (MCF)-like domain of Vibrio vulnificus induces mitochondrion-mediated apoptosis

Agarwal, S., Zhu, Y., Gius, D. R. & Satchell, K. J. F., Jan 1 2015, In : Infection and Immunity. 83, 11, p. 4392-4403 12 p.

Research output: Contribution to journalArticle

Vibrio vulnificus
Mitochondria
Apoptosis
Cysteine Proteases
Poly(ADP-ribose) Polymerases
24 Citations (Scopus)

Vibrio choleraeMARTX toxin heterologous translocation of beta-lactamase and roles of individual effector domains on cytoskeleton dynamics

Dolores, J. S., Agarwal, S., Egerer, M. & Satchell, K. J. F., Feb 1 2015, In : Molecular Microbiology. 95, 4, p. 590-604 15 p.

Research output: Contribution to journalArticle

Vibrio
beta-Lactamases
Cytoskeleton
Actins
Eukaryotic Cells
2014
4 Citations (Scopus)

Backbone and side-chain assignments of an effector membrane localization domain from Vibrio vulnificus MARTX toxin

Brothers, M. C., Geissler, B., Hisao, G. S., Wilson, B. A., Satchell, K. J. F. & Rienstra, C. M., Oct 1 2014, In : Biomolecular NMR Assignments. 8, 2, p. 225-228 4 p.

Research output: Contribution to journalArticle

Vibrio vulnificus
Chemical shift
Membranes
Carbon
Atoms
3 Citations (Scopus)

Backbone and side-chain resonance assignments of the membrane localization domain from Pasteurella multocida toxin

Brothers, M. C., Geissler, B., Hisao, G. S., Satchell, K. J. F., Wilson, B. A. & Rienstra, C. M., Jan 1 2014, In : Biomolecular NMR Assignments. 8, 1, p. 221-224 4 p.

Research output: Contribution to journalArticle

Chemical shift
Crystal structure
Membranes
Proline
Amides
20 Citations (Scopus)

Cytotoxicity of the Vibrio vulnificus MARTX toxin Effector DUF5 is linked to the C2A Subdomain

Antic, I., Biancucci, M. & Satchell, K. J. F., Jan 1 2014, In : Proteins: Structure, Function and Bioinformatics. 82, 10, p. 2643-2656 14 p.

Research output: Contribution to journalArticle

Vibrio vulnificus
Cytotoxicity
HeLa Cells
Photorhabdus
Bacterial Toxins
5 Citations (Scopus)

Draft genome sequence of Israeli outbreak-associated Vibrio vulnificus biotype 3 clinical isolate BAA87

Phillips, K. E., Schipma, M. J. & Satchell, K. J. F., Jan 1 2014, In : Genome Announcements. 2, 2, e00032-14.

Research output: Contribution to journalArticle

Vibrio vulnificus
Disease Outbreaks
Genome
Tilapia
Seafood
30 Citations (Scopus)

Vibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in mice

Ziolo, K. J., Jeong, H. G., Kwak, J. S., Yang, S., Lavker, R. M. & Satchell, K. J. F., Jan 1 2014, In : Infection and Immunity. 82, 5, p. 2148-2157 10 p.

Research output: Contribution to journalArticle

Adenylate Cyclase Toxin
Vibrio vulnificus
Wound Infection
Virulence
Adenylyl Cyclases
2013
18 Citations (Scopus)
Vibrio cholerae
Alleles
Genome
Mutation
Genes
24 Citations (Scopus)

Identification of a His-Asp-Cys catalytic triad essential for function of the rho inactivation domain (RID) of Vibrio cholerae MARTX toxin

Ahrens, S., Geissler, B. & Satchell, K. J. F., Jan 11 2013, In : Journal of Biological Chemistry. 288, 2, p. 1397-1408 12 p.

Research output: Contribution to journalArticle

Vibrio cholerae
Actins
Depolymerization
Mutagenesis
Cholera
16 Citations (Scopus)

Large scale structural rearrangement of a serine hydrolase from francisella tularensis facilitates catalysis

Filippova, E. V., Weston, L. A., Kuhn, M. L., Geissler, B., Gehring, A. M., Armoush, N., Adkins, C. T., Minasov, G., Dubrovska, I., Shuvalova, L., Winsor, J. R., Lavis, L. D., Satchell, K. J. F., Becker, D. P., Anderson, W. F. & Johnson, R. J., Apr 12 2013, In : Journal of Biological Chemistry. 288, 15, p. 10522-10535 14 p.

Research output: Contribution to journalArticle

Francisella tularensis
Hydrolases
Catalysis
Serine
Membranes
9 Citations (Scopus)

Promotion of colonization and virulence by cholera toxin is dependent on neutrophils

Queen, J. & Satchell, K. J. F., Sep 23 2013, In : Infection and Immunity. 81, 9, p. 3338-3345 8 p.

Research output: Contribution to journalArticle

Cholera Toxin
Virulence
Neutrophils
Vibrio cholerae
Vibrio Infections
2012
71 Citations (Scopus)
Vibrio vulnificus
Cytotoxins
Necrosis
Epithelium
Growth
25 Citations (Scopus)
Vibrio cholerae
Intestines
Neutrophils
Infection
Vibrio Infections
24 Citations (Scopus)

Plasma membrane association of three classes of bacterial toxins is mediated by a basic-hydrophobic motif

Geissler, B., Ahrens, S. & Satchell, K. J. F., Feb 1 2012, In : Cellular Microbiology. 14, 2, p. 286-298 13 p.

Research output: Contribution to journalArticle

Bacterial Toxins
Cell Membrane
Membranes
Hydrophobic and Hydrophilic Interactions
Phospholipids
2011
60 Citations (Scopus)
Vibrio vulnificus
Genetic Recombination
Virulence Factors
Infection
Genes
2010
52 Citations (Scopus)
Bacterial Toxins
Bacterial Proteins
Membranes
Cell Membrane
Vibrio vulnificus
2009
19 Citations (Scopus)

Genetic determination of essential residues of the Vibrio oierae actin cross-linking domam reveals functional similarity with glutamine synthetases

Geissler, B., Bonebrake, A., Sheahan, K. L., Walker, M. E. & Satchell, K. J. F., Sep 1 2009, In : Molecular Microbiology. 73, 5, p. 858-868 11 p.

Research output: Contribution to journalArticle

Glutamate-Ammonia Ligase
Vibrio
Actins
Bacterial Toxins
Vibrio cholerae
47 Citations (Scopus)

Structural and molecular mechanism for autoprocessing of MARTX toxin of vibrio cholerae at multiple sites

Prochazkova, K., Shuvalova, L. A., Minasov, G., Voburka, Z., Anderson, W. F. & Satchell, K. J. F., Sep 25 2009, In : Journal of Biological Chemistry. 284, 39, p. 26557-26568 12 p.

Research output: Contribution to journalArticle

Vibrio cholerae
Cysteine Proteases
Leucine
Actins
rho GTP-Binding Proteins
52 Citations (Scopus)

Successful small intestine colonization of adult mice by Vibrio cholerae requires ketamine anesthesia and accessory toxins

Olivier, V., Queen, J. & Satchell, K. J. F., Oct 8 2009, In : PloS one. 4, 10, e7352.

Research output: Contribution to journalArticle

Vibrio cholerae
Hemolysin Proteins
hemolysins
Ketamine
Accessories
85 Citations (Scopus)

The Vibrio cholerae flagellar regulatory hierarchy controls expression of virulence factors

Syed, K. A., Beyhan, S., Correa, N., Queen, J., Liu, J., Peng, F., Satchell, K. J. F., Yildiz, F. & Klose, K. E., Nov 1 2009, In : Journal of Bacteriology. 191, 21, p. 6555-6570 16 p.

Research output: Contribution to journalArticle

Vibrio cholerae
Virulence Factors
Hemolysin Proteins
Virulence
Chitin
2008
30 Citations (Scopus)

Characterization of the enzymatic activity of the actin cross-linking domain from the Vibrio cholerae MARTXVc toxin

Kudryashov, D. S., Cordero, C. L., Reisler, E. & Satchell, K. J. F., Jan 4 2008, In : Journal of Biological Chemistry. 283, 1, p. 445-452 8 p.

Research output: Contribution to journalArticle

Vibrio cholerae
Cholera Toxin
Actins
Microfilament Proteins
Cross Reactions
46 Citations (Scopus)

Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin

Kudryashov, D. S., Oztug Durer, Z. A., Ytterberg, A. J., Sawaya, M. R., Pashkov, I., Prochazkova, K., Yeates, T. O., Ogorzalek Loo, R. R., Loo, J. A., Satchell, K. J. F. & Reisler, E., Nov 25 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 47, p. 18537-18542 6 p.

Research output: Contribution to journalArticle

Actins
Peptides
Vibrio cholerae
Protein Subunits
Vibrio cholerae RtxA protein
41 Citations (Scopus)
Phytic Acid
Vibrio cholerae
Cysteine Proteases
Lysine
Conformations
2007
129 Citations (Scopus)

Auto-catalytic cleavage of Clostridium difficile toxins A and B depends on cysteine protease activity

Egerer, M., Giesemann, T., Jank, T., Satchell, K. J. F. & Aktories, K., Aug 31 2007, In : Journal of Biological Chemistry. 282, 35, p. 25314-25321 8 p.

Research output: Contribution to journalArticle

Glucosyltransferases
Phytic Acid
Ethylmaleimide
Cysteine Proteases
Dithiothreitol
69 Citations (Scopus)

Autoprocessing of the Vibrio cholerae RTX toxin by the cysteine protease domain

Sheahan, K. L., Cordero, C. L. & Satchell, K. J. F., May 16 2007, In : EMBO Journal. 26, 10, p. 2552-2561 10 p.

Research output: Contribution to journalArticle

Bacterial Toxins
Vibrio cholerae
Cysteine Proteases
Cholera Toxin
Crosslinking
31 Citations (Scopus)

Growth phase regulation of Vibrio cholerae RTX toxin export

Boardman, B. K., Meehan, B. M. & Satchell, K. J. F., Mar 1 2007, In : Journal of bacteriology. 189, 5, p. 1827-1835 9 p.

Research output: Contribution to journalArticle

Vibrio cholerae
Cholera
Cholera Toxin
Quorum Sensing
Membranes