Karna Murthy

My interests are within the Children's Hospital Neonatal Consortium (CHNC: http://www.thechnc.org). The CHNC has developed a database focusing on infants with uncommon congenital anomalies and/or acquired complications related to preterm birth in 34 regional NICUs since 2010 in the United States and Canada. We aim to describe the care and outcomes for a population of critically-ill infants that has not been a traditional area of focus in existing registries. Our long term goals are to: (1) establish standards of care and clinical practice guidelines for infants with uncommon but high-acuity illnesses, (2) increase and improve the knowledge base and evidence of care for these infants, (3) reduce unnecessary variation in their care (4) improve their short- and long-term outcomes and (5) maintain and foster a forum of collaboration to persist with these missions. The contemporary descriptions of the populations, prediction of outcomes, and inter-center variations are ongoing for: infants with severe BPD, surgical necrotizing enterocolitis, hypoxic-ischemic encephalopathy, diaphragmatic hernia, and gastroschisis. These data are helpful in family antenatal counseling, in the design of future clinical trials and collaborative quality improvement initiatives.

Health Services Research in Regional Neonatal Intensive Care; Chronic Neonatal/Infant Respiratory Failure

Chronic respiratory failure in infancy, Diaphragmatic Hernia; Consequences of preterm birth;