Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Grants
- 2 Active
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Molecular Mechanisms of eIF4E Mediated Transformation
Borden, K. L. (PD/PI)
12/1/24 → 6/30/26
Project: Research project
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Oncogenic Impact of eIF4E-dependent RNA Export in Cancer
Borden, K. L. (PD/PI)
12/1/24 → 2/28/28
Project: Research project
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No exit: targeting RNA export in T-cell malignancy
Borden, K. L. B., Feb 6 2025, In: Blood. 145, 6, p. 554-556 3 p.Research output: Contribution to journal › Editorial › peer-review
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Medicinal Chemistry and NMR Driven Discovery of Novel UDP-glucuronosyltransferase 1A Inhibitors That Overcome Therapeutic Resistance in Cells
Osborne, M. J., Sulekha, A., Culjkovic-Kraljacic, B., Gasiorek, J., Ruediger, E., Jolicouer, E., Marinier, A., Assouline, S. & Borden, K. L. B., Jan 15 2024, In: Journal of Molecular Biology. 436, 2, 168378.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The eukaryotic translation initiation factor eIF4E unexpectedly acts in splicing thereby coupling mRNA processing with translation: eIF4E induces widescale splicing reprogramming providing system-wide connectivity between splicing, nuclear mRNA export and translation
Borden, K. L. B., Jan 2024, In: BioEssays. 46, 1, 2300145.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
1H, 13C, 15N Backbone and sidechain chemical shift assignments of the C-terminal domain of human UDP-glucuronosyltransferase 2B17 (UGT2B17-C)
Sulekha, A., Osborne, M. J., Gasiorek, J. & Borden, K. L. B., Jun 2023, In: Biomolecular NMR Assignments. 17, 1, p. 67-73 7 p.Research output: Contribution to journal › Article › peer-review
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The eukaryotic translation initiation factor eIF4E reprograms alternative splicing
Ghram, M., Morris, G., Culjkovic-Kraljacic, B., Mars, J. C., Gendron, P., Skrabanek, L., Revuelta, M. V., Cerchietti, L., Guzman, M. L. & Borden, K. L. B., Apr 3 2023, In: EMBO Journal. 42, 7, e110496.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations
Datasets
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SOLUTION STRUCTURE OF THE PHD DOMAIN FROM THE KAP-1 COREPRESSOR
Capili, A. D. (Contributor), Schultz, D. C. (Contributor), Rauscher, F. J. (Contributor) & Borden, K. L. B. (Contributor), Protein Data Bank (PDB), Jan 24 2001
DOI: 10.2210/pdb1FP0/pdb, https://www.wwpdb.org/pdb?id=pdb_00001fp0
Dataset
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NMR assignment of the arenaviral protein Z from Lassa fever virus
Volpon, L. (Contributor), Osborne, M. J. (Contributor), Capul, A. A. (Contributor), De La Torre, J. C. (Contributor) & Borden, K. L. B. (Contributor), Protein Data Bank (PDB), Jan 30 2013
DOI: 10.2210/pdb2M1S/pdb, https://www.wwpdb.org/pdb?id=pdb_00002m1s
Dataset
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The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety
Osborne, M. J. (Contributor), Volpon, L. (Contributor), Kornblatt, J. A. (Contributor), Culjkovic-Kraljacic, B. (Contributor), Baguet, A. (Contributor) & Borden, K. L. B. (Contributor), Biological Magnetic Resonance Data Bank (BMRB), Feb 28 2013
DOI: 10.13018/BMR18663, https://bmrb.io/data_library/summary/index.php?bmrbId=18663
Dataset
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Solution Structure of the C-terminal RING from a RING-IBR-RING (TRIAD) motif
Capili, A. D. (Contributor), Edghill, E. L. (Contributor), Wu, K. (Contributor) & Borden, K. L. B. (Contributor), Protein Data Bank (PDB), Jul 20 2004
DOI: 10.2210/pdb1WD2/pdb, https://www.wwpdb.org/pdb?id=pdb_00001wd2
Dataset
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Crystal structure of the human eIF4E-4EBP1 peptide complex without cap
Siddiqui, N. (Contributor), Tempel, W. (Contributor), Nedyalkova, L. (Contributor), Volpon, L. (Contributor), Wernimont, A. K. (Contributor), Osborne, M. J. (Contributor), Park, H.-W. (Contributor) & Borden, K. L. B. (Contributor), Protein Data Bank (PDB), Nov 2 2011
DOI: 10.2210/pdb3U7X/pdb, https://www.wwpdb.org/pdb?id=pdb_00003u7x
Dataset