Kathleen Janee Green

  • Source: Scopus
1981 …2021

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Research Interests

intercellular junctions, adhesion, desmosomes, adherens junctions, signal transduction, cell motility, skin disease, cadherins, cancer metastasis

Our laboratory is interested in the function and regulation of intercellular junction molecules in desmosomes and adherens junctions that act to mediate cell-cell adhesion and attachment of the cytoskeleton to the cell surface. Defects in junctional components caused by mutation or post-translational modification result in a variety of pathologies ranging from skin and cardiac disease to cancer. In addition, junction-associated molecules are involved in non-junctional functions such as signaling in development and differentiation. The lab uses a multi-faceted approach to dissect the function of cadherins, armadillo and plakin family junction components including but not limited to collaborative atomic structure determinations, molecular genetics, live cell imaging and trangenic mouse approaches.

Expertise related to UN Sustainable Devlopment Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Cell & Developmental Biology, PhD, Washington University

… → 1982

Research interests

  • Cell Adhesion Mechanisms
  • Cell Biology
  • Cutaneous Biology
  • Cytoskeleton
  • Molecular Genetics

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