Grants per year
Personal profile
Research Interests
My research focuses on understanding the connection between heterogeneity in the decisions made by single cells and the success or failure of the immune system to fight bacterial infections.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Massachusetts Institute of Technology
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Collaborations and top research areas from the last five years
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Grants
- 2 Active
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CAREER: Survival Strategies: Using Contextual Cues for Accurate Cell Decision-Making in Changing Environments
Lane, K. M. (PD/PI)
4/1/25 → 3/31/30
Project: Research project
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REU Site: Quantitative Biology REU (QBREU) at Northwestern University
Braun, R. I. (PD/PI), Braun, R. I. (PD/PI), Braun, R. I. (PD/PI), Andersen, E. C. (Co-PD/PI), Andersen, E. C. (Co-PD/PI), Andersen, E. C. (Co-PD/PI), Beitel, G. J. (Co-PD/PI), Beitel, G. J. (Co-PD/PI), Allada, R. (Other), Allada, R. (Other), Allada, R. (Other), Auffinger, A. (Other), Auffinger, A. (Other), Auffinger, A. (Other), Carthew, R. W. (Other), Carthew, R. W. (Other), Carthew, R. W. (Other), Kath, W. L. (Other), Kath, W. L. (Other), Kath, W. L. (Other), Kovacs, I. (Other), Kovacs, I. (Other), Kovacs, I. (Other), LaBonne, C. (Other), LaBonne, C. (Other), LaBonne, C. (Other), Lane, K. M. (Other), Lane, K. M. (Other), Lane, K. M. (Other), Mangan, N. M. (Other), Mangan, N. M. (Other), Mangan, N. M. (Other), Mani, M. (Other), Mani, M. (Other), Mani, M. (Other), Wang, J. (Other), Wang, J. (Other) & Wang, J. (Other)
4/15/22 → 3/31/26
Project: Research project
Research Output
- 18 Article
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A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens
Kudo, T., Lane, K. & Covert, M. W., May 18 2022, In: Cell Systems. 13, 5, p. 376-387.e8Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Navigating Environmental Transitions: the Role of Phenotypic Variation in Bacterial Responses
Spratt, M. R. & Lane, K., Dec 2022, In: mBio. 13, 6Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Simultaneous cross-evaluation of heterogeneous E. coli datasets via mechanistic simulation
Macklin, D. N., Ahn-Horst, T. A., Choi, H., Ruggero, N. A., Carrera, J., Mason, J. C., Sun, G., Agmon, E., DeFelice, M. M., Maayan, I., Lane, K., Spangler, R. K., Gillies, T. E., Paull, M. L., Akhter, S., Bray, S. R., Weaver, D. S., Keseler, I. M., Karp, P. D. & Morrison, J. H. & 1 others, , Jul 24 2020, In: Science. 369, 6502, eaav3751.Research output: Contribution to journal › Article › peer-review
Open Access103 Scopus citations -
Combinatorial processing of bacterial and host-derived innate immune stimuli at the single-cell level
Gutschow, M. V., Mason, J. C., Lane, K. M., Maayan, I., Hughey, J. J., Bajar, B. T., Amatya, D. N., Valle, S. D. & Covert, M. W., Jan 15 2019, In: Molecular biology of the cell. 30, 2, p. 282-292 11 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Escalating Threat Levels of Bacterial Infection Can Be Discriminated by Distinct MAPK and NF-κB Signaling Dynamics in Single Host Cells
Lane, K. M., Andres-Terre, M., Kudo, T., Monack, D. M. & Covert, M. W., Mar 27 2019, In: Cell Systems. 8, 3, p. 183-196.e4Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations