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Personal profile

Education/Academic qualification

Chemical Engineering, PhD, Massachusetts Institute of Technology

… → 2008

Chemical Engineering, MS, Massachusetts Institute of Technology

… → 2003

Chemical Engineering, BS, West Virginia University

… → 2001

Research interests

  • Global health
  • Metabolic engineering
  • Synthetic biology

Fingerprint Dive into the research topics where Keith Edward Jaggard Tyo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Metabolic Engineering Medicine & Life Sciences
Metabolic engineering Chemical Compounds
Yeast Chemical Compounds
Yeasts Medicine & Life Sciences
Saccharomyces cerevisiae Medicine & Life Sciences
Proteins Engineering & Materials Science
DNA-Directed DNA Polymerase Medicine & Life Sciences
Libraries Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2011 2022

Nucleic Acids
DNA-Directed DNA Polymerase
DNA-Directed RNA Polymerases
DNA
Brain
Biofuels
Metabolism
Recycling
Enzymes
Metabolic engineering
Metabolic Networks and Pathways
Synthetic Biology
Metabolic Engineering
1-Butanol
Terpenes

Research Output 2005 2019

Bayesian inference of metabolic kinetics from genome-scale multiomics data

John, P. C. S., Strutz, J., Broadbelt, L. J., Tyo, K. E. J. & Bomble, Y. J., Jan 1 2019, In : PLoS computational biology. 15, 11, e1007424.

Research output: Contribution to journalArticle

Open Access
Bayesian inference
Genome
genome
Genes
Kinetics

Chemically inducible chromosomal evolution (CIChE) for multicopy metabolic pathway engineering

Love, A. M., Biggs, B. W., Tyo, K. E. J. & Ajikumar, P. K., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc, p. 37-45 9 p. (Methods in Molecular Biology; vol. 1927).

Research output: Chapter in Book/Report/Conference proceedingChapter

Metabolic Engineering
Gene Duplication
Metabolic Networks and Pathways
Anti-Bacterial Agents
Workflow
2 Citations (Scopus)

Kinetic ensemble model of gas fermenting Clostridium autoethanogenum for improved ethanol production

Greene, J., Daniell, J., Köpke, M., Broadbelt, L. J. & Tyo, K. E. J., Aug 15 2019, In : Biochemical Engineering Journal. p. 46-56 11 p.

Research output: Contribution to journalArticle

Clostridium
Ethanol
Gases
Kinetics
Kinetic parameters

Metabolic in silico network expansions to predict and exploit enzyme promiscuity

Jeffryes, J., Strutz, J., Henry, C. & Tyo, K. E. J., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc, p. 11-21 11 p. (Methods in Molecular Biology; vol. 1927).

Research output: Chapter in Book/Report/Conference proceedingChapter

Computer Simulation
Enzymes
Metabolomics
Biotransformation
Databases
1 Citation (Scopus)

Metabolic kinetic modeling provides insight into complex biological questions, but hurdles remain

Strutz, J., Martin, J., Greene, J., Broadbelt, L. & Tyo, K., Oct 2019, In : Current Opinion in Biotechnology. 59, p. 24-30 7 p.

Research output: Contribution to journalReview article

Kinetics
Identification (control systems)
Metabolic engineering
Cell Engineering
Metabolic Engineering