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Personal profile

Education/Academic qualification

Chemical Engineering, PhD, Massachusetts Institute of Technology

… → 2008

Chemical Engineering, MS, Massachusetts Institute of Technology

… → 2003

Chemical Engineering, BS, West Virginia University

… → 2001

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Metabolic Engineering Medicine & Life Sciences
Metabolic engineering Engineering & Materials Science
Yeast Chemical Compounds
Yeasts Medicine & Life Sciences
Saccharomyces cerevisiae Medicine & Life Sciences
Proteins Engineering & Materials Science
Synthetic Biology Medicine & Life Sciences
DNA-Directed DNA Polymerase Medicine & Life Sciences

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Grants 2011 2022

Nucleic Acids
DNA-Directed DNA Polymerase
DNA-Directed RNA Polymerases
DNA
Brain
Biofuels
Metabolism
Recycling
Enzymes
Metabolic engineering
Metabolic Networks and Pathways
Synthetic Biology
Metabolic Engineering
1-Butanol
Terpenes
Neurons
DNA
Equipment and Supplies
Brain Diseases
Connectome

Research Output 2005 2019

Chemically inducible chromosomal evolution (CIChE) for multicopy metabolic pathway engineering

Love, A. M., Biggs, B. W., Tyo, K. E. J. & Ajikumar, P. K., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc, p. 37-45 9 p. (Methods in Molecular Biology; vol. 1927).

Research output: Chapter in Book/Report/Conference proceedingChapter

Metabolic Engineering
Gene Duplication
Metabolic Networks and Pathways
Anti-Bacterial Agents
Workflow

Kinetic ensemble model of gas fermenting Clostridium autoethanogenum for improved ethanol production

Greene, J., Daniell, J., Köpke, M., Broadbelt, L. J. & Tyo, K. E. J., Aug 15 2019, In : Biochemical Engineering Journal. 148, p. 46-56 11 p.

Research output: Contribution to journalArticle

Clostridium
Ethanol
Gases
Kinetics
Carbon Monoxide

Metabolic in silico network expansions to predict and exploit enzyme promiscuity

Jeffryes, J., Strutz, J., Henry, C. & Tyo, K. E. J., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc, p. 11-21 11 p. (Methods in Molecular Biology; vol. 1927).

Research output: Chapter in Book/Report/Conference proceedingChapter

Computer Simulation
Enzymes
Metabolomics
Biotransformation
Databases

Metabolic kinetic modeling provides insight into complex biological questions, but hurdles remain

Strutz, J., Martin, J., Greene, J., Broadbelt, L. J. & Tyo, K. E. J., Oct 1 2019, In : Current Opinion in Biotechnology. 59, p. 24-30 7 p.

Research output: Contribution to journalReview article

Kinetics
Identification (control systems)
Metabolic engineering
Cell Engineering
Metabolic Engineering

Correction to: Detection of a Peptide Biomarker by Engineered Yeast Receptors (ACS Synthetic Biology (2018) 7:2 (696-705) DOI: 10.1021/acssynbio.7b00410)

Adeniran, A., Stainbrook, S., Bostick, J. W. & Tyo, K. E. J., Aug 17 2018, In : ACS synthetic biology. 7, 8, 1 p.

Research output: Contribution to journalComment/debate

Synthetic Biology
Manuscripts
Biomarkers
Yeast
Peptides