Grants per year
Personal profile
Research Interests
Dr. Gates’ clinical interests include pulmonary infections, COPD, asthma, and sepsis. Her research interests relate to impairment of pulmonary host defense and immune mechanisms which contribute to pulmonary disease.
Certifications and Licenses
| Pulmonary Disease | |
| Internal Medicine | |
| Critical Care Medicine |
Training Experience
| 2004 | Internship, Loyola University Medical Center |
| 2007 | Residency, Loyola University Medical Center |
| 2010 | Fellowship, Northwestern University, McGaw Medical Center |
Education/Academic qualification
MD, Loyola University/Stritch School of Medicine
… → 2003
Keywords
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
- Critical Care
- Immune Regulation
- Pneumonia
- Sepsis
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
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Hypercapnia
Medicine & Life Sciences
Macrophages
Medicine & Life Sciences
Lung
Medicine & Life Sciences
Interleukin-6
Chemical Compounds
Alveolar Macrophages
Medicine & Life Sciences
Chronic Obstructive Pulmonary Disease
Medicine & Life Sciences
Pulmonary diseases
Chemical Compounds
Pseudomonas
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2011 2016
- 1 Finished
Hypercapnia and Neutrophil Function in Pulmonary Host Defense
Gates, K. L., Sporn, P. H. & Sznajder, J. I.
National Heart, Lung, and Blood Institute
9/12/11 → 7/31/16
Project: Research project
Hypercapnia
Neutrophils
Lung
Lung Diseases
Research
Research Output 2010 2019
Mechanism of benefit of non-invasive ventilation in COPD with hypercapnic respiratory failure
Sporn, P. H., Casalino Matsuda, M. S. & Gates, K. L., May 1 2019, In : Respirology. 24, 5, 1 p.Research output: Contribution to journal › Letter
Noninvasive Ventilation
Respiratory Insufficiency
Chronic Obstructive Pulmonary Disease
1
Citation
(Scopus)
A role for heat shock factor 1 in hypercapnia-induced inhibition of inflammatory cytokine expression
Lu, Z., Casalino Matsuda, M. S., Nair, A., Buchbinder, A., Budinger, GR. S., Sporn, P. H. & Gates, K. L., Jul 1 2018, In : FASEB Journal. 32, 7, p. 3614-3622 9 p.Research output: Contribution to journal › Article
Hypercapnia
Shock
Hot Temperature
Cytokines
Interleukin-6
86
Citations
(Scopus)
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
Misharin, A. V., Morales-Nebreda, L., Reyfman, P. A., Cuda, C. M., Walter, J. M., McQuattie-Pimentel, A. C., Chen, C. I., Anekalla, K. R., Joshi, N., Williams, K. J. N., Abdala-Valencia, H., Yacoub, T. J., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Gates, K., Lam, A. P., Nicholson, T. T., Homan, P. J., Soberanes, S. & 23 others, Aug 1 2017, In : Journal of Experimental Medicine. 214, 8, p. 2387-2404 18 p.Research output: Contribution to journal › Article
Alveolar Macrophages
Fibrosis
Macrophages
Lung
Monocytes
21
Citations
(Scopus)
Hypercapnia inhibits autophagy and bacterial killing in human macrophages by increasing expression of Bcl-2 and Bcl-xL
Casalino-Matsuda, S. M., Nair, A., Beitel, G. J., Gates, K. L. & Sporn, P. H. S., Jan 1 2015, In : Journal of Immunology. 194, 11, p. 5388-5396 9 p.Research output: Contribution to journal › Article
Hypercapnia
Autophagy
Macrophages
Lung Diseases
Bacteria
41
Citations
(Scopus)
Hypercapnia impairs lung neutrophil function and increases mortality in murine Pseudomonas pneumonia
Gates, K. L., Howell, H. A., Nair, A., Vohwinkel, C. U., Welch, L. C., Beitel, G. J., Hauser, A. R., Sznajder, J. I. & Sporn, P. H. S., Nov 1 2013, In : American Journal of Respiratory Cell and Molecular Biology. 49, 5, p. 821-828 8 p.Research output: Contribution to journal › Article
Hypercapnia
Pseudomonas
Pneumonia
Pulmonary diseases
Neutrophils