Kurt Lu

  • 449 Citations
20032022
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Personal profile

Training Experience

2003Internship, Columbia University Medical Center
2005Postdoctoral Fellowship, Case Western Reserve University
2008Residency, University Hospitals Case Medical Center, Cleveland OH

Research Interests

Dr. Lu, MD, FAAD, is the Eugene and Gloria Bauer Professor of Dermatology. Dr. Lu is a dermatologist who completed his undergraduate degree in immunology and microbiology from the University of Rochester and earned his medical degree from University of Rochester School of Medicine in New York. He completed internship at Columbia University and a combined residency and post-doctoral fellowship in molecular and cellular dermatology at Case Western Reserve University and University Hospitals of Cleveland. After his training, Dr. Lu stayed on as a faculty member at Case Western Reserve University for more than a decade prior to joining Northwestern University Feinberg School of Medicine in 2018 as an associate professor.

Dr. Lu's research interests focus on understanding and controlling inflammation in the skin. Working in the area of translational biology, Dr. Lu’s work spans the gamut from cell biology, to model organisms, to clinical trials. He is the director of the in vivo skin testing unit and associate director of the Translational and Experimental Skin Testing & Immune Tracing (TEST IT) core at the Northwestern University Skin Biology and Diseases Resource-based Center (SBDRC). The goal of his work is to ultimately translate the findings into the development of therapeutics for mediating skin and wound repair. He has developed methods for repurposing drugs, such as the use of ultra-high doses of vitamin D3 in controlling innate immune activation in the skin. His work has led to national and international recognition for the potential use of vitamin D3 and other immune-modifying drugs following skin injury in clinical scenarios such as UV sunburns and skin wounds from toxic chemical exposure. Dr. Lu’s work in the area of chemical exposures has shifted the focus in the field of skin toxicology towards the underlying immune response as a strategy for the development of therapeutics.

Dr. Lu has a broad interest in general and medical dermatology, photo-dermatology, and auto-immune skin diseases such as lupus.

Education/Academic qualification

MD, University of Rochester

… → 2002

Fingerprint Dive into the research topics where Kurt Lu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Skin Medicine & Life Sciences
Sunburn Medicine & Life Sciences
Macrophages Medicine & Life Sciences
Vitamin D Medicine & Life Sciences
Mechlorethamine Medicine & Life Sciences
Skin Neoplasms Medicine & Life Sciences
rosiglitazone Medicine & Life Sciences
Local Neoplasm Recurrences Medicine & Life Sciences

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Grants 2018 2022

Research Output 2003 2019

3 Citations (Scopus)

Vitamin D improves sunburns by increasing autophagy in M2 macrophages

Das, L. M., Binko, A. M., Traylor, Z. P., Peng, H. & Lu, K. Q., May 4 2019, In : Autophagy. 15, 5, p. 813-826 14 p.

Research output: Contribution to journalArticle

Sunburn
Autophagy
Vitamin D
Macrophages
Skin
2 Citations (Scopus)

Defining the timing of 25(OH)D rescue following nitrogen mustard exposure

Das, L. M., Binko, A. M., Traylor, Z. P., Duesler, L. & Lu, K. Q., Apr 3 2018, In : Cutaneous and Ocular Toxicology. 37, 2, p. 127-132 6 p.

Research output: Contribution to journalArticle

Mechlorethamine
Toxicity
Recovery
Wounds and Injuries
Calcifediol
2 Citations (Scopus)

Evaluation of o6-benzylguanine?Potentiated topical carmustine formycosis fungoides a phase 1-2 clinical trial

Tacastacas, J. D., Chan, D. V., Carlson, S., Gerson, S. L., Dowlati, A., Fu, P., Lu, K., Groft, S., Rosenjack, J., Honda, K., McCormick, T. S. & Cooper, K. D., May 2017, In : JAMA dermatology. 153, 5, p. 413-420 8 p.

Research output: Contribution to journalArticle

Carmustine
Clinical Trials, Phase I
Maximum Tolerated Dose
Dermatitis
Cutaneous T-Cell Lymphoma
15 Citations (Scopus)

Oral Vitamin D Rapidly Attenuates Inflammation from Sunburn: An Interventional Study

Scott, J. F., Das, L. M., Ahsanuddin, S., Qiu, Y., Binko, A. M., Traylor, Z. P., Debanne, S. M., Cooper, K. D., Boxer, R. & Lu, K. Q., Oct 2017, In : Journal of Investigative Dermatology. 137, 10, p. 2078-2086 9 p.

Research output: Contribution to journalArticle

Sunburn
Cholecalciferol
Vitamin D
Skin
Inflammation
5 Citations (Scopus)

Vitamin D as a Therapeutic Option for Sunburn: Clinical and Biologic Implications

Scott, J. F. & Lu, K. Q., Nov 1 2017, In : DNA and Cell Biology. 36, 11, p. 879-882 4 p.

Research output: Contribution to journalArticle

Sunburn
Vitamin D
Therapeutics