• 11144 Citations
1978 …2024
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Personal profile

Research Interests

papillomaviruses, cervical cancer, epithelila cells, diffrentiation

Training Experience

1985Fellowship, National Institutes of Health

Education/Academic qualification

PhD, University of Chicago

… → 1981

Keywords

  • Microbiology
  • Viral Oncology
  • Cancer: Female Reproductive System (ovary, cervix, uterus)

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  • 9 Similar Profiles
Papillomaviridae Agriculture & Biology
Human papillomavirus 31 Medicine & Life Sciences
Life Cycle Stages Medicine & Life Sciences
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Genome Medicine & Life Sciences
Proteins Medicine & Life Sciences
Viral Genome Medicine & Life Sciences
Oncogene Proteins Medicine & Life Sciences

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Grants 2001 2024

Gene Expression
Life Cycle Stages
Transcription Factors
Viral Genome
DNA Repair
Sirtuin 1
Life Cycle Stages
DNA Damage
Keratinocytes
Viral Genome
Ataxia Telangiectasia
DNA Damage
Human Genome
Viral Genome
Life Cycle Stages
Viral DNA
Neoplasms
Life Cycle Stages
Uterine Cervical Neoplasms

Research Output 1978 2019

DNA Repair
DNA Damage
Papillomaviridae
Uterine Cervical Neoplasms
Ataxia Telangiectasia Mutated Proteins

Topoisomerase IIβ-binding protein 1 activates expression of E2F1 and p73 in HPV-positive cells for genome amplification upon epithelial differentiation

Hong, S., Xu, J., Li, Y., Andrade, J., Hoover, P., Kaminski, P. J. & Laimins, L. A., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Type II DNA Topoisomerase
Ataxia Telangiectasia
Carrier Proteins
Genome
DNA Damage
7 Citations (Scopus)

Human papillomaviruses preferentially recruit DNA repair factors to viral genomes for rapid repair and amplification

Mehta, K. & Laimins, L. A., Jan 1 2018, In : mBio. 9, 1, e00064-18.

Research output: Contribution to journalArticle

Viral Genome
DNA Repair
Ataxia Telangiectasia
DNA Breaks
DNA
13 Citations (Scopus)

FANCD2 binds human papillomavirus genomes and associates with a distinct set of DNA repair proteins to regulate viral replication

Spriggs, C. C. & Laimins, L. A., Jan 1 2017, In : mBio. 8, 1, e02340-16.

Research output: Contribution to journalArticle

Human Genome
DNA Repair
Fanconi Anemia
Proteins
Ataxia Telangiectasia
6 Citations (Scopus)

Human papillomavirus and the DNA damage response: Exploiting host repair pathways for viral replication

Spriggs, C. C. & Laimins, L. A., Feb 18 2017, In : Viruses. 9, 8, 232.

Research output: Contribution to journalReview article

DNA Damage
Ataxia Telangiectasia
Papillomavirus Infections
DNA Repair
Oropharyngeal Neoplasms