Grants per year
Personal profile
Research Interests
papillomaviruses, cervical cancer, epithelila cells, diffrentiation
Training Experience
| 1985 | Fellowship, National Institutes of Health |
Education/Academic qualification
PhD, University of Chicago
… → 1981
Keywords
- Microbiology
- Viral Oncology
- Cancer: Female Reproductive System (ovary, cervix, uterus)
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- 9 Similar Profiles
Papillomaviridae
Agriculture & Biology
Human papillomavirus 31
Medicine & Life Sciences
Life Cycle Stages
Medicine & Life Sciences
Keratinocytes
Medicine & Life Sciences
Genome
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Oncogene Proteins
Medicine & Life Sciences
Viral Genome
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2001 2024
Gene Expression
Life Cycle Stages
Transcription Factors
Viral Genome
DNA Repair
Regulation of HPV Replication by Sirtuin Deacetylases
National Institute of Allergy and Infectious Diseases
7/15/17 → 6/30/20
Project: Research project
Sirtuin 1
Life Cycle Stages
DNA Damage
Keratinocytes
Viral Genome
Ataxia Telangiectasia
DNA Damage
Human Genome
Viral Genome
Life Cycle Stages
Control of E1 oligomerization regulates E1 function in papillomavirus DNA replication
Cold Spring Harbor Laboratory, National Institute of Allergy and Infectious Diseases
5/1/15 → 4/30/20
Project: Research project
DNA Replication
Viral DNA
Proteins
Human papillomavirus 31
Foreskin
Role of CTCF in HPV replication and viral DNA looping
National Institute of Allergy and Infectious Diseases
7/1/15 → 6/30/18
Project: Research project
Viral DNA
Neoplasms
Life Cycle Stages
Uterine Cervical Neoplasms
Research Output 1978 2019
Expression of HPV-induced DNA damage repair factors correlates with CIN progression
Spriggs, C. C., Blanco Jr, L. Z., Maniar, K. P. & Laimins, L. A., Jan 1 2019, In : International Journal of Gynecological Pathology. 38, 1, p. 1-10 10 p.Research output: Contribution to journal › Article
DNA Repair
DNA Damage
Papillomaviridae
Uterine Cervical Neoplasms
Ataxia Telangiectasia Mutated Proteins
Topoisomerase IIβ-binding protein 1 activates expression of E2F1 and p73 in HPV-positive cells for genome amplification upon epithelial differentiation
Hong, S., Xu, J., Li, Y., Andrade, J., Hoover, P., Kaminski, P. J. & Laimins, L. A., Apr 25 2019, In : Oncogene. 38, 17, p. 3274-3287 14 p.Research output: Contribution to journal › Article
Type II DNA Topoisomerase
Ataxia Telangiectasia
Carrier Proteins
Genome
DNA Damage
Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
Zhao, J., Lee, E. E., Kim, J., Yang, R., Chamseddin, B., Ni, C., Gusho, E., Xie, Y., Chiang, C. M., Buszczak, M., Zhan, X., Laimins, L. A. & Wang, R. C., Dec 1 2019, In : Nature communications. 10, 1, 2300.Research output: Contribution to journal › Article
Open Access
Oncogene Proteins
coding
cancer
viruses
oncogenes
8
Citations
(Scopus)
Human papillomaviruses preferentially recruit DNA repair factors to viral genomes for rapid repair and amplification
Mehta, K. & Laimins, L. A., Jan 1 2018, In : mBio. 9, 1, e00064-18.Research output: Contribution to journal › Article
Viral Genome
DNA Repair
Ataxia Telangiectasia
DNA Breaks
DNA
14
Citations
(Scopus)
FANCD2 binds human papillomavirus genomes and associates with a distinct set of DNA repair proteins to regulate viral replication
Spriggs, C. C. & Laimins, L. A., Jan 1 2017, In : mBio. 8, 1, e02340-16.Research output: Contribution to journal › Article
Human Genome
DNA Repair
Fanconi Anemia
Proteins
Ataxia Telangiectasia