Grants per year
Personal profile
Research Interests
My research interests are in the areas of healthcare epidemiology and infection prevention and control, particularly Clostridium difficile infections. I am exploring various aspects of C. difficile infection, including clinical and molecular epidemiology, diagnosis, antibiotic resistance, and host immune response. The primary aims of my K23-funded translational research are to optimize the diagnosis of C. difficile infection by validating several existing and emerging diagnostic testing strategies in children with the ultimate goal of accurately differentiating C. difficile colonization and infection. Other areas of investigation includes the use of whole genome sequencing to assess antibiotic resistance determinants and virulence factors of emerging strains of C. difficile, namely DH/NAP11/106, as well as identifying transmission and evolution of C. difficile clones in a pediatric population.
Healthcare epidemiology; infection prevention and control; Clostridium difficile; bacterial genomics
All areas of pediatric infectious diseases, with a particular interest in healthcare-associated infections, Clostridium difficile infection, and infections caused by antibiotic resistant organisms.
Training Experience
2010 | Residency, University of Chicago Hospitals |
2014 | Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
Education/Academic qualification
MSCI, Northwestern University, Feinberg School of Medicine
… → 2015
MD, Saint Louis University
… → 2006
Research interests
- Bacteriology
- Epidemiology
- Genomics
- Infectious Diseases
- Microbiology
- Molecular Diagnostics
- Pediatrics
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Grants
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Optimizing the diagnosis of pediatric Clostridium difficile infection
National Institute of Allergy and Infectious Diseases
2/15/16 → 1/31/21
Project: Research project
Research Output
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Comparison of upper respiratory viral load distributions in asymptomatic and symptomatic children diagnosed with SARS-CoV-2 infection in pediatric hospital testing programs
Kociolek, L. K., Muller, W. J., Yee, R., Bard, J. D., Brown, C. A., Revell, P. A., Wardell, H., Savage, T. J., Jung, S., Dominguez, S., Parikh, B. A., Jerris, R. C., Kehl, S. C., Campigotto, A., Bender, J. M., Zheng, X., Muscat, E., Linam, M., Abuogi, L., Smith, C. & 4 others, , Jan 2021, In: Journal of clinical microbiology. 59, 1, e02593-20.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Age-related differences in nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) levels in patients with mild to moderate coronavirus disease 2019 (COVID-19)
Heald-Sargent, T., Muller, W. J., Zheng, X., Rippe, J., Patel, A. B. & Kociolek, L. K., Sep 1 2020, In: JAMA Pediatrics. 174, 9, p. 902-903 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access33 Scopus citations -
Association Between Children's Hospital Visitor Restrictions and Healthcare-Associated Viral Respiratory Infections: A Quasi-Experimental Study
Forkpa, H., Rupp, A. H., Shulman, S. T., Patel, S. J., Gray, E. L., Zheng, X., Bovee, M. & Kociolek, L. K., Apr 30 2020, In: Journal of the Pediatric Infectious Diseases Society. 9, 2, p. 240-243 4 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Benign course of SARS-CoV-2 infection in a series of pediatric oncology patients
Rossoff, J., Patel, A. B., Muscat, E., Kociolek, L. K. & Muller, W. J., Sep 1 2020, In: Pediatric Blood and Cancer. 67, 9, e28504.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Complete genome sequence of clostridium innocuum strain ATCC 14501
Cherny, K. E., Ozer, E. A., Kochan, T. J. & Kociolek, L. K., Jul 23 2020, In: Microbiology Resource Announcements. 9, 30, e00452-20.Research output: Contribution to journal › Article › peer-review
Open Access