Grants per year
Personal profile
Research Interests
My research interests are in the areas of healthcare epidemiology and infection prevention and control, particularly Clostridium difficile infections. I am exploring various aspects of C. difficile infection, including clinical and molecular epidemiology, diagnosis, antibiotic resistance, and host immune response. The primary aims of my K23-funded translational research are to optimize the diagnosis of C. difficile infection by validating several existing and emerging diagnostic testing strategies in children with the ultimate goal of accurately differentiating C. difficile colonization and infection. Other areas of investigation includes the use of whole genome sequencing to assess antibiotic resistance determinants and virulence factors of emerging strains of C. difficile, namely DH/NAP11/106, as well as identifying transmission and evolution of C. difficile clones in a pediatric population.
Healthcare epidemiology; infection prevention and control; Clostridium difficile; bacterial genomics
All areas of pediatric infectious diseases, with a particular interest in healthcare-associated infections, Clostridium difficile infection, and infections caused by antibiotic resistant organisms.
Training Experience
| 2010 | Residency, University of Chicago Hospitals |
| 2014 | Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MSCI, Northwestern University
… → 2015
MD, Medicine, Saint Louis University
… → 2006
Research interests keywords
- Bacteriology
- Epidemiology
- Genomics
- Infectious Diseases
- Microbiology
- Molecular Diagnostics
- Pediatrics
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Grants
- 18 Finished
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Main Account
Ozer, E. A. (PD/PI), Bachta, K. E. R. (Other), D'Aquila, R. T. (Other), Hauser, A. R. (Other), Hope, T. J. (Other), Hultquist, J. F. (Other), Kociolek, L. K. (Other), Lorenzo Redondo, R. (Other), Murphy, R. L. (Other) & Taiwo, B. O. (Other)
Office of the Director, National Institutes of Health
5/15/23 → 5/14/24
Project: Research project
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Identifying the Breadth of Antibody Responses to Clostridioides difficile Infection
Kociolek, L. K. (PD/PI)
National Institute of Allergy and Infectious Diseases, National Institutes of Health
6/9/20 → 6/29/22
Project: Research project
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Clostridium innocuum as an emerging multidrug-resistant antibiotic-associated diarrheal pathogen
Kociolek, L. K. (PD/PI)
National Institute of Allergy and Infectious Diseases, National Institutes of Health
1/24/19 → 3/31/21
Project: Research project
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Clostridium innocuum as an emerging multidrug-resistant antibiotic-associated diarrheal pathogen
Kociolek, L. K. (PD/PI)
National Institute of Allergy and Infectious Diseases, National Institutes of Health
1/24/19 → 3/31/21
Project: Research project
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Acute Flaccid Myelitis Enhanced Surveillance
Kociolek, L. K. (Co-Investigator)
Chicago Department of Public Health
9/24/18 → 6/30/19
Project: Research project
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Children’s Hospital Resource Utilization During the 2022 Viral Respiratory Surge
Michelson, K. A., Ramgopal, S., Kociolek, L. K., Zerr, D. M., Neuman, M. I., Bettenhausen, J. L., Hall, M. & Macy, M. L., Jul 1 2024, In: Pediatrics. 154, 1, e2024065974.Research output: Contribution to journal › Article › peer-review
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Coronary Artery Outcomes in Kawasaki Disease by Treatment Day Within 10 Days of Fever Onset
Karandikar, V. M., Khan, H., Kim, K. Y. A., Kociolek, L. K., Jhaveri, R., Shulman, S. T. & Rowley, A. H., Jul 1 2024, In: Open Forum Infectious Diseases. 11, 7, ofae352.Research output: Contribution to journal › Article › peer-review
Open Access -
Infection Prevention and Control Implications of Special Pathogens in Children
Kociolek, L. K., Shane, A. L., Simonsen, K. A. & Zerr, D. M., Jun 2024, In: Pediatric Clinics of North America. 71, 3, p. 431-454 24 p.Research output: Contribution to journal › Review article › peer-review
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Mycoplasma pneumoniae: delayed re-emergence after COVID-19 pandemic restrictions
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Mycoplasma and Chlamydia Infections (ESGMAC), and the ESGMAC Mycoplasma pneumoniae Surveillance (MAPS) study group, Feb 2024, In: The Lancet Microbe. 5, 2, p. e100-e101Research output: Contribution to journal › Comment/debate › peer-review
Open Access63 Scopus citations -
Pneumonia outbreaks due to re-emergence of Mycoplasma pneumoniae
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Mycoplasma and Chlamydia Infections (ESGMAC), and the ESGMAC Mycoplasma pneumoniae Surveillance (MAPS) study group, Jun 2024, In: The Lancet Microbe. 5, 6, p. e514Research output: Contribution to journal › Letter › peer-review
Open Access6 Scopus citations
Datasets
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Surveillance Cultures and Infection in 230 Pacemaker and Defibrillator Generator Changes in Pediatric and Adult Congenital Patients
Webster, G. (Creator), Balmert, L. C. (Creator), Patel, A. B. (Creator), Kociolek, L. K. (Creator), Gevitz, M. (Creator), Olson, R. (Creator), Chaouki, A. S. (Creator), El-Tayeb, O. (Creator), Monge, M. C. (Creator) & Backer, C. (Creator), SAGE Journals, 2021
DOI: 10.25384/sage.c.5418452, https://sage.figshare.com/collections/Surveillance_Cultures_and_Infection_in_230_Pacemaker_and_Defibrillator_Generator_Changes_in_Pediatric_and_Adult_Congenital_Patients/5418452
Dataset