• 97 Citations
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Personal profile

Research Interests

Dr. L. Nelson Sanchez-Pinto is a pediatric critical care physician, biomedical informatics specialist, and clinical data scientist. He graduated from medical school at the Autonomous University of Barcelona in 2006, and then completed a Pediatrics residency program at Cincinnati Children's Hospital Medical Center in 2011, and a fellowship in Pediatric Critical Care Medicine at Children's Hospital Los Angeles (CHLA) in 2014. He obtained advanced fellowship training in informatics and data science research also at CHLA and completed a Masters of Biomedical Informatics program at Oregon Health & Science University in 2015. He then joined The University of Chicago as faculty where he obtained a KL2 Career Development Award. He later joined the faculty in the Departments of Pediatric and Preventive Medicine at Northwestern University Feinberg School of Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago in 2017.

Dr. Sanchez-Pinto is interested in discovering and evaluating data-driven phenotypes of critical illness by integrating clinical, physiologic, and multi-omics data. Dr. Sanchez-Pinto is particularly interested in developing data-driven approaches to study the complex interactions between the host response, the gut and lung microbiomes, and other clinical and genetic factors in patients with sepsis, acute respiratory distress syndrome (ARDS), and multiple organ dysfunction syndrome (MODS). His ultimate goal is to discover subgroups of patients who have similar phenotypes –and potentially similar response to targeted therapy– in order to develop a personalized approach to critical illness. More at: https://www.luriechildrens.org/en/specialties-conditions/pediatric-critical-care/research/primer-picu-study/

Dr. Sanchez-Pinto is a pediatric critical care specialist and treats critically ill children with sepsis, ARDS, and MODS, as well as a host of other conditions. He has a special interest in advanced respiratory support, vasoplegia management, oxidative stress therapy, and metabolic support.

Training Experience

2011Residency, Cincinnati Children's Hospital Medical Center
2014Fellowship, Children's Hospital, Los Angeles

Education/Academic qualification

MBI, Oregon Health & Science University

… → 2015

MD, Autonomous University of Barcelona

… → 2006

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Research Output 2011 2019

  • 97 Citations
  • 10 Article
  • 3 Chapter
  • 2 Review article
1 Citation (Scopus)

Early prediction of acute kidney injury following ICU admission using a multivariate panel of physiological measurements

Zimmerman, L. P., Reyfman, P. A., Smith, A. D. R., Zeng, Z., Kho, A. N., Sanchez-Pinto, L. N. & Luo, Y., Jan 31 2019, In : BMC Medical Informatics and Decision Making. 19, 16.

Research output: Contribution to journalArticle

Acute Kidney Injury
Intensive Care Units
Critical Care
Logistic Models
1 Citation (Scopus)

Autonomic Nervous System Dysfunction in Pediatric Sepsis

Badke, C. M., Marsillio, L. E., Weese-Mayer, D. E. & Sanchez-Pinto, L. N., 2018, In : Frontiers in Pediatrics. 6, p. 280

Research output: Contribution to journalReview article

Autonomic Nervous System
Body Temperature Regulation
Critical Illness
8 Citations (Scopus)

Big Data and Data Science in Critical Care

Sanchez-Pinto, L. N., Luo, Y. & Churpek, M. M., Nov 1 2018, In : CHEST. 154, 5, p. 1239-1248 10 p.

Research output: Contribution to journalReview article

Critical Care
Information Systems
Critical Illness
5 Citations (Scopus)

Comparison of variable selection methods for clinical predictive modeling

Sanchez-Pinto, L. N., Venable, L. R., Fahrenbach, J. & Churpek, M. M., Aug 1 2018, In : International Journal of Medical Informatics. 116, p. 10-17 8 p.

Research output: Contribution to journalArticle

Logistic Models
Acute Kidney Injury

Implementation of a risk-stratified opioid and benzodiazepine weaning protocol in a pediatric cardiac ICU

Amirnovin, R., Sanchez-Pinto, L. N., Okuhara, C., Lieu, P., Koh, J. Y., Rodgers, J. W. & Nelson, L. P., Jan 1 2018, In : Pediatric Critical Care Medicine. 19, 11, p. 1024-1032 9 p.

Research output: Contribution to journalArticle

Opioid Analgesics
Critical Illness