Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Pharmacology and Toxicology, Western University
… → 2015
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Dive into the research topics where Leah Katherine Cuddy is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Grants
- 2 Active
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Vasculo-neuronal pathophysiological interface in Alzheimer’s and Atherosclerosis
Arispe, L. (PD/PI), Vassar, R. J. (PD/PI), Cuddy, L. K. (Other) & Sadleir, K. R. (Other)
National Institute of Neurological Disorders and Stroke
9/18/24 → 8/31/27
Project: Research project
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Mechanisms of Angiotensin I Converting Enzyme in Alzheimer's disease
Vassar, R. J. (PD/PI), Cuddy, L. K. (Co-Investigator), Gate, D. (Co-Investigator) & Savas, J. N. (Co-Investigator)
12/15/22 → 11/30/25
Project: Research project
Research Output
- 12 Article
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Neuronal ACE1 knockout disrupts the hippocampal renin angiotensin system leading to memory impairment and vascular loss in normal aging
Jeon, S., Salvo, M. A., Alia, A. O., Popovic, J., Zagardo, M., Chandra, S., Nassan, M., Gate, D., Vassar, R. & Cuddy, L. K., Nov 2024, In: Neurobiology of Disease. 202, 106729.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluating the association between genetically proxied ACE inhibition and dementias
Nassan, M., Daghlas, I., Piras, I. S., Rogalski, E., Reus, L. M., Pijnenburg, Y., Cuddy, L. K., Saxena, R., Mesulam, M. M. & Huentelman, M., Sep 2023, In: Alzheimer's and Dementia. 19, 9, p. 3894-3901 8 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms
Chandra, S., Di Meco, A., Dodiya, H. B., Popovic, J., Cuddy, L. K., Weigle, I. Q., Zhang, X., Sadleir, K., Sisodia, S. S. & Vassar, R., Dec 2023, In: Molecular neurodegeneration. 18, 1, 45.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Aberrant glial activation and synaptic defects in CaMKIIα-iCre and nestin-Cre transgenic mouse models
Alia, A. O., Jeon, S., Popovic, J., Salvo, M. A., Sadleir, K. R., Vassar, R. & Cuddy, L. K., Dec 2022, In: Scientific reports. 12, 1, 22099.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice
Cuddy, L. K., Alia, A. O., Salvo, M. A., Chandra, S., Grammatopoulos, T. N., Justman, C. J., Lansbury, P. T., Mazzulli, J. R. & Vassar, R., Dec 2022, In: Molecular neurodegeneration. 17, 1, 54.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations
Datasets
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Additional file 11 of The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms
Chandra, S. (Creator), Di Meco, A. (Creator), Dodiya, H. B. (Creator), Popovic, J. (Creator), Cuddy, L. K. (Creator), Weigle, I. Q. (Creator), Zhang, X. (Creator), Sadleir, K. (Creator), Sisodia, S. S. (Creator) & Vassar, R. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.26988550.v1, https://springernature.figshare.com/articles/dataset/Additional_file_11_of_The_gut_microbiome_regulates_astrocyte_reaction_to_A_amyloidosis_through_microglial_dependent_and_independent_mechanisms/26988550/1
Dataset
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Additional file 4 of Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice
Cuddy, L. K. (Creator), Alia, A. O. (Creator), Salvo, M. A. (Creator), Chandra, S. (Creator), Grammatopoulos, T. N. (Creator), Justman, C. J. (Creator), Lansbury, P. T. (Creator), Mazzulli, J. R. (Creator) & Vassar, R. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.20522621, https://springernature.figshare.com/articles/figure/Additional_file_4_of_Farnesyltransferase_inhibitor_LNK-754_attenuates_axonal_dystrophy_and_reduces_amyloid_pathology_in_mice/20522621
Dataset
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Additional file 12 of The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms
Chandra, S. (Creator), Di Meco, A. (Creator), Dodiya, H. B. (Creator), Popovic, J. (Creator), Cuddy, L. K. (Creator), Weigle, I. Q. (Creator), Zhang, X. (Creator), Sadleir, K. (Creator), Sisodia, S. S. (Creator) & Vassar, R. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.26988553.v1, https://springernature.figshare.com/articles/dataset/Additional_file_12_of_The_gut_microbiome_regulates_astrocyte_reaction_to_A_amyloidosis_through_microglial_dependent_and_independent_mechanisms/26988553/1
Dataset
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Additional file 10 of The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms
Chandra, S. (Creator), Di Meco, A. (Creator), Dodiya, H. B. (Creator), Popovic, J. (Creator), Cuddy, L. K. (Creator), Weigle, I. Q. (Creator), Zhang, X. (Creator), Sadleir, K. (Creator), Sisodia, S. S. (Creator) & Vassar, R. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.26988547.v1, https://springernature.figshare.com/articles/dataset/Additional_file_10_of_The_gut_microbiome_regulates_astrocyte_reaction_to_A_amyloidosis_through_microglial_dependent_and_independent_mechanisms/26988547/1
Dataset
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Additional file 2 of Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice
Cuddy, L. K. (Creator), Alia, A. O. (Creator), Salvo, M. A. (Creator), Chandra, S. (Creator), Grammatopoulos, T. N. (Creator), Justman, C. J. (Creator), Lansbury, P. T. (Creator), Mazzulli, J. R. (Creator) & Vassar, R. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.20522615, https://springernature.figshare.com/articles/figure/Additional_file_2_of_Farnesyltransferase_inhibitor_LNK-754_attenuates_axonal_dystrophy_and_reduces_amyloid_pathology_in_mice/20522615
Dataset