Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
20062024

Research activity per year

Personal profile

Research Interests

Dr. Cooper received his PhD in Electrical and Computer Engineering from Ohio State University in 2009. He joined the Biomedical Informatics faculty at Emory University in 2012 where he was jointly appointed with Biomedical Engineering at Georgia Institute of Technology. He joined the department of pathology at Northwestern in 2019 as an Associate Professor and Director of Computational Pathology.

My lab focuses on the applications of machine learning in cancer and fundamental research in machine learning. We develop algorithms to predict clinical outcomes from genomic, imaging, and histopathology data, and to extract quantitative descriptions of tissue microenvironments from digital pathology images. Our work has produced a number of software tools that enable researchers to manage large and complex datasets and to interact with these data using machine learning algorithms. Our goal is to improve the quality of predictions used in clinical management and to provide investigators with new insights in cancer biology. Our research has been funded by NLM, NCI, NIBIB, NINDS, and industry and foundation sources.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD, Electrical Engineering and Computer Science, Ohio State University

… → 2009

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Collaborations and top research areas from the last five years

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  • A population-level digital histologic biomarker for enhanced prognosis of invasive breast cancer

    Amgad, M., Hodge, J. M., Elsebaie, M. A. T., Bodelon, C., Puvanesarajah, S., Gutman, D. A., Siziopikou, K. P., Goldstein, J. A., Gaudet, M. M., Teras, L. R. & Cooper, L. A. D., Jan 2024, In: Nature Medicine. 30, 1, p. 85-97 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Automated Deep Learning-Based Diagnosis and Molecular Characterization of Acute Myeloid Leukemia Using Flow Cytometry

    Lewis, J. E., Cooper, L. A. D., Jaye, D. L. & Pozdnyakova, O., Jan 2024, In: Modern Pathology. 37, 1, 100373.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Focused active learning for histopathological image classification

    Schmidt, A., Morales-Álvarez, P., Cooper, L. A., Newberg, L. A., Enquobahrie, A., Molina, R. & Katsaggelos, A. K., Jul 2024, In: Medical Image Analysis. 95, 103162.

    Research output: Contribution to journalArticlepeer-review

  • Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer

    Jahangir, C. A., Page, D. B., Broeckx, G., Gonzalez, C. A., Burke, C., Murphy, C., Reis-Filho, J. S., Ly, A., Harms, P. W., Gupta, R. R., Vieth, M., Hida, A. I., Kahila, M., Kos, Z., van Diest, P. J., Verbandt, S., Thagaard, J., Khiroya, R., Abduljabbar, K. & Acosta Haab, G. & 117 others, Acs, B., Adams, S., Almeida, J. S., Alvarado-Cabrero, I., Azmoudeh-Ardalan, F., Badve, S., Baharun, N. B., Bellolio, E. R., Bheemaraju, V., Blenman, K. R. M., Botinelly Mendonça Fujimoto, L., Burgues, O., Chardas, A., Cheang, M. C. U., Ciompi, F., Cooper, L. A. D., Coosemans, A., Corredor, G., Dantas Portela, F. L., Deman, F., Demaria, S., Dudgeon, S. N., Elghazawy, M., Fernandez-Martín, C., Fineberg, S., Fox, S. B., Giltnane, J. M., Gnjatic, S., Gonzalez-Ericsson, P. I., Grigoriadis, A., Halama, N., Hanna, M. G., Harbhajanka, A., Hart, S. N., Hartman, J., Hewitt, S., Horlings, H. M., Husain, Z., Irshad, S., Janssen, E. A. M., Kataoka, T. R., Kawaguchi, K., Khramtsov, A. I., Kiraz, U., Kirtani, P., Kodach, L. L., Korski, K., Akturk, G., Scott, E., Kovács, A., Lænkholm, A. V., Lang-Schwarz, C., Larsimont, D., Lennerz, J. K., Lerousseau, M., Li, X., Madabhushi, A., Maley, S. K., Manur Narasimhamurthy, V., Marks, D. K., McDonald, E. S., Mehrotra, R., Michiels, S., Kharidehal, D., Minhas, F. U. A. A., Mittal, S., Moore, D. A., Mushtaq, S., Nighat, H., Papathomas, T., Penault-Llorca, F., Perera, R. D., Pinard, C. J., Pinto-Cardenas, J. C., Pruneri, G., Pusztai, L., Rajpoot, N. M., Rapoport, B. L., Rau, T. T., Ribeiro, J. M., Rimm, D., Vincent-Salomon, A., Saltz, J., Sayed, S., Hytopoulos, E., Mahon, S., Siziopikou, K. P., Sotiriou, C., Stenzinger, A., Sughayer, M. A., Sur, D., Symmans, F., Tanaka, S., Taxter, T., Tejpar, S., Teuwen, J., Thompson, E. A., Tramm, T., Tran, W. T., van der Laak, J., Verghese, G. E., Viale, G., Wahab, N., Walter, T., Waumans, Y., Wen, H. Y., Yang, W., Yuan, Y., Bartlett, J., Loibl, S., Denkert, C., Savas, P., Loi, S., Specht Stovgaard, E., Salgado, R., Gallagher, W. M. & Rahman, A., Mar 2024, In: Journal of Pathology. 262, 3, p. 271-288 18 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    1 Scopus citations
  • Learning from crowds for automated histopathological image segmentation

    López-Pérez, M., Morales-Álvarez, P., Cooper, L. A. D., Felicelli, C., Goldstein, J., Vadasz, B., Molina, R. & Katsaggelos, A. K., Mar 2024, In: Computerized Medical Imaging and Graphics. 112, 102327.

    Research output: Contribution to journalArticlepeer-review

    Open Access