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Personal profile

Research Interests

The three fundamental goals of my research are the following: 1) To understand the nature of the brain's own signals -- the "language" in which movement commands are expressed by neurons in the central nervous system. 2) To understand the mechanisms by which these signals are produced -- the nature of the connections among networks of neurons, and the transformations that occur in the signals as they propagate throughout these networks. 3) To develop applications of these basic principles that could be of therapeutic value to human patients. Much of this work is done in collaboration with students and faculty from the Biomedical Engineering Department and the Interdepartmental Neuroscience Program (NUIN).

Training Experience

1992Postdoctoral Fellowship, University of Nijmegen

Education/Academic qualification

PhD, Northwestern University

… → 1990


  • Movement Control
  • Neural Engineering
  • Neuroscience
  • Spinal Cord Injury

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Grants 2002 2023

Brain computer interface
Prostheses and Implants

Research Output 1984 2019

A muscle-activity-dependent gain between motor cortex and emg

Naufel, S., Glaser, J. I., Kording, K. P., Perreault, E. & Miller, L. E., Jan 1 2019, In : Journal of neurophysiology. 121, 1, p. 61-73 13 p.

Research output: Contribution to journalArticle

Motor Cortex
Brain-Computer Interfaces
Contact Lenses
Macaca mulatta

Cortically Controlled FES for Restoration and Rehabilitation of Function Following SCI in Rats

Barroso, F. O., Yoder, B., Wallner, J., Jantz, M., Tostado, P., Pei, E., Tysseling, V. M., Miller, L. E. & Tresch, M. C., Jan 1 2019, Biosystems and Biorobotics. Springer International Publishing, p. 931-934 4 p. (Biosystems and Biorobotics; vol. 21).

Research output: Chapter in Book/Report/Conference proceedingChapter

Patient rehabilitation

Decoding neural activity to predict rat locomotion using intracortical and epidural arrays

Barroso, F. O., Yoder, B., Tentler, D., Wallner, J. J., Kinkhabwala, A. A., Jantz, M. K., Flint, R. D., Tostado, P. M., Pei, E., Satish, A. D. R., Brodnick, S. K., Suminski, A. J., Williams, J. C., Miller, L. E. & Tresch, M. C., Jan 1 2019, In : Journal of Neural Engineering. 16, 3, 036005.

Research output: Contribution to journalArticle

Functional electric stimulation
Biped locomotion
Brain-Computer Interfaces
Digital storage

Neural networks for modeling neural spiking in S1 cortex

Lucas, A., Tomlinson, T., Rohani, N., Chowdhury, R., Solla, S. A., Katsaggelos, A. K. & Miller, L. E., Jan 24 2019, In : Frontiers in Systems Neuroscience. 13, 13.

Research output: Contribution to journalArticle

Open Access
Biomechanical Phenomena
Neural Networks (Computer)
4 Citations (Scopus)

A Neural Population Mechanism for Rapid Learning

Perich, M. G., Gallego, J. A. & Miller, L. E., Nov 21 2018, In : Neuron. 100, 4, p. 964-976.e7

Research output: Contribution to journalArticle

Motor Cortex