Lee E Miller

Professor, Physiology
Professor, Biomedical Engineering
Professor, Physical Medicine and Rehabilitation
Affiliate, Biomedical Engineering PhD Program
Core, Northwestern University Interdepartmental Neuroscience PhD Program (NUIN)

Phone312/503-8677
Emaillm@northwestern.edu

3387 Citations

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Personal profile

Research Interests

The three fundamental goals of my research are the following: 1) To understand the nature of the brain's own signals -- the "language" in which movement commands are expressed by neurons in the central nervous system. 2) To understand the mechanisms by which these signals are produced -- the nature of the connections among networks of neurons, and the transformations that occur in the signals as they propagate throughout these networks. 3) To develop applications of these basic principles that could be of therapeutic value to human patients. Much of this work is done in collaboration with students and faculty from the Biomedical Engineering Department and the Interdepartmental Neuroscience Program (NUIN).

Training Experience

1992	Postdoctoral Fellowship, University of Nijmegen

Education/Academic qualification

PhD, Northwestern University

… → 1990

Research interests

Movement Control
Neural Engineering
Neuroscience
Spinal Cord Injury

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2002 2024

9 Active
24 Finished

Optimizing the restoration and rehabilitation of function using cortically-controlled FES following SCI

Miller, L. E., Tresch, M. C. & Tysseling, V. M.

National Institute of Neurological Disorders and Stroke

7/1/19 → 4/30/24

Project: Research project

Spinal Cord Stimulation

Spinal Cord Injuries

Electric Stimulation

Rehabilitation

Muscles

Stable neural interfaces through artificial intelligence-based manifold discovery

Miller, L. E.

Emory University, Defense Advanced Research Projects Agency (DARPA)

4/19/19 → 10/18/19

Project: Research project

Artificial Intelligence

Motor Cortex

Primates

Population

Collaborative Research: NCS-FO: Discovering dynamics in massive-scale neural datasets using machine learning

Miller, L. E.

National Science Foundation

10/1/18 → 9/30/21

Project: Research project

Learning systems

Muscle

Brain

Primates

Scalable Electrode Technology for High Resolution Chronic Recording of Brain

Miller, L. E.

University of Texas at Dallas, National Institute of Neurological Disorders and Stroke

9/1/18 → 8/31/23

Project: Research project

Amorphous silicon

Silicon carbide

Brain

Electrodes

Experiments

A primate model of an intra-cortically controlled FES prosthesis for grasp

Miller, L. E., Mussa-Ivaldi, F., Perreault, E. & Solla, S. A.

National Institute of Neurological Disorders and Stroke

9/1/17 → 7/31/22

Project: Research project

Brain computer interface

Brain

Muscle

Prosthetics

Prostheses and Implants

Research Output 1984 2019

3387 Citations
90 Article
17 Chapter
10 Conference contribution
9 Review article
3 More

A muscle-activity-dependent gain between motor cortex and emg

Naufel, S., Glaser, J. I., Kording, K. P., Perreault, E. & Miller, L. E., Jan 1 2019, In : Journal of neurophysiology. 121, 1, p. 61-73 13 p.

Research output: Contribution to journal › Article

Motor Cortex

Brain-Computer Interfaces

Muscles

Contact Lenses

Macaca mulatta

Cortically Controlled FES for Restoration and Rehabilitation of Function Following SCI in Rats

Barroso, F. O., Yoder, B., Wallner, J., Jantz, M., Tostado, P., Pei, E., Tysseling, V. M., Miller, L. E. & Tresch, M. C., Jan 1 2019, Biosystems and Biorobotics. Springer International Publishing, p. 931-934 4 p. (Biosystems and Biorobotics; vol. 21).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Patient rehabilitation

Restoration

Rats

Muscle

Electrodes

Decoding neural activity to predict rat locomotion using intracortical and epidural arrays

Barroso, F. O., Yoder, B., Tentler, D., Wallner, J. J., Kinkhabwala, A. A., Jantz, M. K., Flint, R. D., Tostado, P. M., Pei, E., Satish, A. D. R., Brodnick, S. K., Suminski, A. J., Williams, J. C., Miller, L. E. & Tresch, M. C., Jan 1 2019, In : Journal of Neural Engineering. 16, 3, 036005.

Research output: Contribution to journal › Article

Locomotion

Decoding

Rats

Hindlimb

Brain-Computer Interfaces

Neural networks for modeling neural spiking in S1 cortex

Lucas, A., Tomlinson, T., Rohani, N., Chowdhury, R., Solla, S. A., Katsaggelos, A. K. & Miller, L. E., Jan 24 2019, In : Frontiers in Systems Neuroscience. 13, 13.

Research output: Contribution to journal › Article

Open Access

Touch

Biomechanical Phenomena

Neurons

Proprioception

Neural Networks (Computer)

6 Citations (Scopus)

A Neural Population Mechanism for Rapid Learning

Perich, M. G., Gallego, J. A. & Miller, L. E., Nov 21 2018, In : Neuron. 100, 4, p. 964-976.e7

Research output: Contribution to journal › Article

Motor Cortex

Learning

Population