Grants per year
Personal profile
Research Interests
The three fundamental goals of my research are the following: 1) To understand the nature of the brain's own signals -- the "language" in which movement commands are expressed by neurons in the central nervous system. 2) To understand the mechanisms by which these signals are produced -- the nature of the connections among networks of neurons, and the transformations that occur in the signals as they propagate throughout these networks. 3) To develop applications of these basic principles that could be of therapeutic value to human patients. Much of this work is done in collaboration with students and faculty from the Biomedical Engineering Department and the Interdepartmental Neuroscience Program (NUIN).
Training Experience
1992 | Postdoctoral Fellowship, University of Nijmegen |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Physiology, Northwestern University
… → 1990
Research interests keywords
- Movement Control
- Neural Engineering
- Neuroscience
- Spinal Cord Injury
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Monkey-to-human transfer of trained iBCI decoders through nonlinear alignment of neural population dynamics
Miller, L. E. (PD/PI) & Kennedy, A. (Co-PD/PI)
National Institute of Neurological Disorders and Stroke
9/6/23 → 8/31/25
Project: Research project
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Improved Brain-Computer Interface Decoding for Activities of Daily Life
Miller, L. E. (PD/PI)
The University of Chicago, National Institute of Neurological Disorders and Stroke
8/15/23 → 7/31/28
Project: Research project
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Development of an EMG-controlled BCI for biomimetic control of hand movement in humans
Miller, L. E. (PD/PI)
National Institute of Neurological Disorders and Stroke
4/1/23 → 3/31/28
Project: Research project
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Pathophysiology and Rehabilitation of Neural Dysfunction
Hargrove, L. J. (PD/PI), Perreault, E. (PD/PI), Perreault, E. (PD/PI), Perreault, E. (PD/PI), Perreault, E. (Co-PD/PI), Hargrove, L. J. (Other), Hargrove, L. J. (Other), Hargrove, L. J. (Other), Miller, L. E. (Other), Miller, L. E. (Other), Roth, E. J. (Other) & Roth, E. J. (Other)
National Institute of Child Health and Human Development
5/1/22 → 4/30/27
Project: Research project
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Human and Machine Learning for Customized Control of Assistive Robots
argall, B. D. (PD/PI), argall, B. D. (PD/PI), argall, B. D. (PD/PI), Miller, L. E. (Co-Investigator), Mussa Ivaldi, F. (Co-Investigator) & Mussa Ivaldi, F. (Co-Investigator)
Rehabilitation Institute of Chicago, National Institute of Biomedical Imaging and Bioengineering
9/1/18 → 5/31/25
Project: Research project
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A neural implementation model of feedback-based motor learning
Feulner, B., Perich, M. G., Miller, L. E., Clopath, C. & Gallego, J. A., Dec 2025, In: Nature communications. 16, 1, 1805.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Less is more: selection from a small set of options improves BCI velocity control
Alcolea, P. I., Ma, X., Bodkin, K., Miller, L. E. & Danziger, Z. C., Apr 1 2025, In: Journal of Neural Engineering. 22, 2, 026018.Research output: Contribution to journal › Article › peer-review
Open Access -
Tactile edges and motion via patterned microstimulation of the human somatosensory cortex
Valle, G., Alamri, A. H., Downey, J. E., Lienkämper, R., Jordan, P. M., Sobinov, A. R., Endsley, L. J., Prasad, D., Boninger, M. L., Collinger, J. L., Warnke, P. C., Hatsopoulos, N. G., Miller, L. E., Gaunt, R. A., Greenspon, C. M. & Bensmaia, S. J., Jan 17 2025, In: Science. 387, 6731, p. 315-322 8 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Unsupervised, piecewise linear decoding enables an accurate prediction of muscle activity in a multi-task brain computer interface
Ma, X., Rizzoglio, F., Bodkin, K. L. & Miller, L. E., Feb 1 2025, In: Journal of Neural Engineering. 22, 1, 016019.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
An Evolution of Assistive Robot Control to Meet End-User Ability
Thompson, A., Rizzoglio, F., Neylon, F. A., Barsoum, D. R., Ammon, L. E., McCune, M. N., Miller, L. & Argall, B., Mar 11 2024, HRI 2024 Companion - Companion of the 2024 ACM/IEEE International Conference on Human-Robot Interaction. IEEE Computer Society, p. 1048-1052 5 p. (ACM/IEEE International Conference on Human-Robot Interaction).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Open Access
Datasets
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Area2_Bump: macaque somatosensory area 2 spiking activity during reaching with perturbations
Miller, L. (Creator), Pei, F. (Contributor) & Chowdhury, R. (Contributor), DANDI Archive, 2022
DOI: 10.48324/dandi.000127/0.220113.0359, https://dandiarchive.org/dandiset/000127/0.220113.0359
Dataset
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Data from: Area 2 of primary somatosensory cortex encodes kinematics of the whole arm
Chowdhury, R. H. (Contributor), Glaser, J. I. (Contributor) & Miller, L. E. (Contributor), ZENODO, May 20 2022
DOI: 10.5061/dryad.nk98sf7q7, https://zenodo.org/records/5010943
Dataset
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BRAND: A platform for closed-loop experiments with deep network models
Ali, Y. H. (Contributor), Bodkin, K. (Contributor), Rigotti-Thompson, M. (Contributor), Patel, K. (Contributor), Card, N. S. (Contributor), Bhaduri, B. (Contributor), Nason-Tomaszewski, S. R. (Contributor), Mifsud, D. M. (Contributor), Hou, X. (Contributor), Nicolas, C. (Contributor), Allcroft, S. (Contributor), Hochberg, L. R. (Contributor), Yong, N. A. (Contributor), Stavisky, S. D. (Contributor), Miller, L. E. (Contributor), Brandman, D. M. (Contributor) & Pandarinath, C. (Contributor), ZENODO, Jan 22 2024
DOI: 10.5281/zenodo.10547705, https://zenodo.org/records/10547705
Dataset
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Local field potentials reflect cortical population dynamics in a region-specific and frequency-dependent manner
Gallego-Carracedo, C. (Creator), Perich, M. G. (Creator), Chowdhury, R. H. (Creator), Miller, L. E. (Creator) & Gallego, J. A. (Creator), Dryad, Aug 16 2022
DOI: 10.5061/dryad.xd2547dkt, https://datadryad.org/stash/dataset/doi:10.5061/dryad.xd2547dkt
Dataset
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Local field potentials reflect cortical population dynamics in a region-specific and frequency-dependent manner
Gallego-Carracedo, C. (Contributor), Perich, M. G. (Contributor), Chowdhury, R. H. (Contributor), Miller, L. E. (Contributor) & Gallego, J. A. (Contributor), ZENODO, Aug 29 2022
DOI: 10.5061/dryad.xd2547dkt, https://zenodo.org/records/7055668
Dataset