Grants per year
Personal profile
Research Interests
My interests are focused on diagnosis and treatment of children with Gastrointestinal and Liver disease. Specifically, I focus on gastrointestinal endoscopy, both for diagnostic purposes but also for new modalities of therapy and diagnostics including treatment of GI bleeding, complex polyposis syndromes, Gastrointestinal Strictures, treatment of Portal Hypertension, capsule endoscopy, Single Balloon Enteroscopy and new techniques such as Trans-nasal Endoscopy. I have an interest in cholestatic liver disease and participate in the Childhood Liver Disease Research and Education Network (CHiLDREN). As part of this collaborative I am a member of working groups in Progressive Familial Intrahepatic Cholestasis, Biliary Atresia, Alpha-1-Anti-trypsin deficiency and Portal Hypertension. I also am the principal investigator for Lurie Children's Hospital for the Fibroscan in Cholestatic Liver Disease study. In addition to this work, I have an interest in use of technology to provide behavioral modification for children with functional disorders
My academic focus is primarily in the realm of Pediatric Cholestatic Liver Disease. I am a co-Investigator for the Childhood Liver Disease Research Network and have participated in publications involving Progressive Familial Intrahepatic Cholestasis, Biliary Atresia, and alpha-1-anti-trypsin deficiency. I am the lead investigator for several studies within the network assessing portal hypertension and outcome of portal hypertension. I am the principal investigator for the Fibroscan in Cholestatic Liver disease study (FORCE). As the director of endoscopy, I have an academic interest in new techniques for endoscopic procedures in children and have published several papers on Capsule Endoscopy in Children and am participating in ongoing multi-center collaborations evaluating gastrointestinal bleeding and trans nasal endoscopy.
As the Director of Endoscopy at Lurie Children's Hospital my main clinical focus is advancing our ability to perform therapeutic and interventional endoscopy. For the last several years, I have been the director of the GI bleeding team, a group of physicians who remain on call year round to provide back up for patients with gastrointestinal hemorrhage. I have mentored my colleagues in new techniques of treating GI bleeding and have been a nationally recognized expert in this area. I have introduced new techniques for treating GI bleeding to Lurie Children's Hospital. I have also been one one of the first physicians in the country to perform Trans-nasal endoscopy on children- in order to diagnose children with upper gastrointestinal disorders without using general anesthesia. I have developed the capsule endoscopy program at Lurie Children's to be one of the most robust programs in the country and have also pioneered the use of Single balloon endoscope deep enteroscopy at our institution. I also have a strong interest in taking care of children with gastrointestinal strictures and complex polyposis syndromes.
Certifications and Licenses
Pediatric Gastroenterology | |
Pediatrics |
Training Experience
2008 | Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
Education/Academic qualification
Medicine, MD, Rush Medical College
… → 2001
Research interests keywords
- Digestive System (including gallbladder and liver)
- Gastrointestinal Bleeding
- Liver Disease / Pathobiology
- Pediatric Gastroenterology
- Small Bowel Disorders
- Video Capsule Endoscopy
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Collaborations and top research areas from the last five years
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BLI800-502: A Safety and Efficacy Study of a Bowel Cleansing Preparation (BLI800) in Pediatric Subjects Undergoing Colonoscopy
Bass, L. M. (PD/PI)
5/1/17 → 8/31/50
Project: Research project
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ChiLDReN, the Childhood Liver Disease Research Network
Alonso, E. M. (PD/PI), Bass, L. M. (Co-Investigator), Melin-Aldana, H. (Co-Investigator) & Taylor, S. A. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
9/18/19 → 5/31/24
Project: Research project
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FibroScan in Pediatric Cholestatic Liver Disease
Bass, L. M. (PD/PI)
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases
10/1/16 → 5/31/20
Project: Research project
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FibroScan in Pediatric Cholestatic Liver Disease
Bass, L. M. (PD/PI)
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases
10/1/16 → 5/31/20
Project: Research project
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FibroScan in Pediatric Cholestatic Liver Disease
Bass, L. M. (PD/PI)
Arbor Research Collaborative for Health, National Institute of Diabetes and Digestive and Kidney Diseases
10/1/16 → 5/31/20
Project: Research project
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Anastomotic Ulcers: Current Understanding of the Pathogenesis and Management
McKay, S., Cohran, V. & Bass, L. M., Jul 2023, In: Current gastroenterology reports. 25, 7, p. 169-173 5 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Gastrointestinal Bleeding in Children: Current Management, Controversies, and Advances
Novak, I. & Bass, L. M., Apr 2023, In: Gastrointestinal Endoscopy Clinics of North America. 33, 2, p. 401-421 21 p.Research output: Contribution to journal › Review article › peer-review
8 Scopus citations -
Heart rate variability is associated with encephalopathy and outcomes in pediatric acute liver failure
Pendergrast, T. R., Chapin, C. A., Kriegermeier, A. A., Pardo, A. C., Bass, L. M. & Sanchez-Pinto, L. N., Apr 2023, In: Pediatric research. 93, 5, p. 1348-1353 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Neonatal cholestasis in children with Alpha-1-AT deficiency is a risk for earlier severe liver disease with male predominance
the ChiLDReN (Childhood Liver Disease Research Network), Dec 2023, In: Hepatology Communications. 7, 12, e0345.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease
the Childhood Liver Disease Research Network, Feb 2023, In: Hepatology. 77, 2, p. 530-545 16 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations