Leena Sharma

  • 11208 Citations
1992 …2022
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Personal profile

Research Interests

The overarching goals of our research program are to identify targets for novel strategies to prevent disease and disability development and progression in persons at risk for or with knee osteoarthritis.

Certifications and Licenses

Internal Medicine

Training Experience

1987Residency, University of Texas Medical Branch Hospital
1989Fellowship, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital)

Education/Academic qualification

MD, Medical College of Wisconsin

… → 1984


  • Disability
  • Epidemiology
  • Health Services Research
  • Osteoarthritis
  • Public Health
  • Rheumatology

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Grants 2002 2022

Disease Progression

Research Output 1992 2019

Cartilage loss in radiographically normal knees depends on radiographic status of the contralateral knee – data from the Osteoarthritis Initiative

Eckstein, F., Maschek, S., Roemer, F. W., Duda, G. N., Sharma, L. & Wirth, W., Feb 1 2019, In : Osteoarthritis and Cartilage. 27, 2, p. 273-277 5 p.

Research output: Contribution to journalArticle

Knee Osteoarthritis
Magnetic resonance imaging
Knee Osteoarthritis
Body Mass Index
Odds Ratio
Confidence Intervals
4 Citations

Association of baseline knee sagittal dynamic joint stiffness during gait and 2-year patellofemoral cartilage damage worsening in knee osteoarthritis

Chang, A. H-I., Chmiel, J. S., Almagor, O., Guermazi, A., Prasad, P. V., Moisio, K. C., Belisle, L., Zhang, Y., Hayes, K. & Sharma, L., Feb 1 2017, In : Osteoarthritis and Cartilage. 25, 2, p. 242-248 7 p.

Research output: Contribution to journalArticle

Knee Osteoarthritis
2 Citations

Do inactive older adults who increase physical activity experience less disability, evidence from the osteoarthritis initiative

Song, J., Gilbert, A. L., Chang, R. W., Pellegrini, C. A., Ehrlich-Jones, L. S., Lee, J., Pinto, D., Semanik, P. A., Sharma, L., Kwoh, C. K., Jackson, R. D. & Dunlop, D. D., Jan 1 2017, In : Journal of Clinical Rheumatology. 23, 1, p. 26-32 7 p.

Research output: Contribution to journalArticle

Knee Osteoarthritis
United States Dept. of Health and Human Services
7 Citations

Knee tissue lesions and prediction of incident knee osteoarthritis over 7 years in a cohort of persons at higher risk

Sharma, L., Hochberg, M., Nevitt, M., Guermazi, A., Roemer, F., Crema, M. D., Eaton, C., Jackson, R., Kwoh, K., Cauley, J., Almagor, O. & Chmiel, J. S., Jul 1 2017, In : Osteoarthritis and Cartilage. 25, 7, p. 1068-1075 8 p.

Research output: Contribution to journalArticle

Knee Osteoarthritis
Bone Marrow