Leonidas C Platanias

  • 20937 Citations
1985 …2024
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Personal profile

Research Interests

chronic leukemias, multiple myeloma, non-hodgkin's lymphoma

Certifications and Licenses

Internal Medicine
Medical Oncology

Training Experience

1984Residency, Hellenic Anticancer Institute
1989Residency, SUNY/State University of New York Downstate Medical Center
1992Fellowship, University of Chicago Hospitals

Education/Academic qualification

PhD, University of Patras Medical School

… → 1989

MD, University of Patras Medical School

… → 1983

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Grants 2001 2024

Cyclin-Dependent Kinase 9
Protein Transport
Acute Myeloid Leukemia
Protein Biosynthesis
Heterografts
grant
cancer
funding
scientific journal
pilot project
grant
cancer
funding
scientific journal
pilot project
Gastrointestinal Neoplasms
Research
Neoplasms
Research Personnel
Government Agencies

Research Output 1985 2019

1 Citation (Scopus)

Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

Beauchamp, E. M., Abedin, S. M., Radecki, S. G., Fischietti, M., Arslan, A. D., Blyth, G. T., Yang, A., Lantz, C., Nelson, A., Goo, Y. A., Akpan, I., Eklund, E. A., Frankfurt, O., Fish, E. N., Thomas, P. M., Altman, J. K. & Platanias, L. C., Mar 14 2019, In : Blood. 133, 11, p. 1171-1185 15 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 9
Sirolimus
Acute Myeloid Leukemia
Cytoplasm
Chemical activation

Natural killer cell activity and survival after azacitidine treatment in high-risk MDS

Abedin, S. M. & Platanias, L. C., Jan 1 2019, In : Leukemia and Lymphoma.

Research output: Contribution to journalComment/debate

Azacitidine
Natural Killer Cells
Cell Survival

Potent Antineoplastic Effects of Combined PI3Kα-MNK Inhibition in Medulloblastoma

Eckerdt, F. D., Bell, J. B., Beauchamp, E. M., Clymer, J., Blyth, G. T., Kosciuczuk, E. M., Ma, Q., Chen, D. Z., Horbinski, C. M., Goldman, S., Munshi, H. G., Hashizume, R. & Platanias, L. C., Jun 1 2019, In : Molecular cancer research : MCR. 17, 6, p. 1305-1315 11 p.

Research output: Contribution to journalArticle

Medulloblastoma
Mitogen-Activated Protein Kinase Kinases
Phosphatidylinositol 3-Kinases
Antineoplastic Agents
Neoplastic Stem Cells

Sirtuin 2–mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses

Kosciuczuk, E. M., Mehrotra, S., Nora Vaz Saleiro, D., Kroczynska, B., Majchrzak-Kita, B., Lisowski, P., Driehaus, C., Rogalska, A., Turner, A., Lienhoop, T., Gius, D. R., Fish, E. N., Vasilopoulos, A. & Platanias, L. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 3, p. 827-837 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 9
Interferon Type I
Sirtuin 2
Interferons
Transcription

Antineoplastic effects of selective CDK9 inhibition with atuveciclib on cancer stem-like cells in triple-negative breast cancer

Brisard, D., Eckerdt, F. D., Marsh, L. A., Blyth, G. T., Jain, S., Cristofanilli, M., Horiuchi, D. & Platanias, L. C., Dec 1 2018, In : Oncotarget. 9, 99, p. 37305-37318 14 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 9
Triple Negative Breast Neoplasms
Neoplastic Stem Cells
Antineoplastic Agents
Recurrence