Leonidas C Platanias

Professor, Medicine, Hematology Oncology Division
Professor, Biochemistry and Molecular Genetics
Associate Dean for Cancer Program, Feinberg School of Medicine, Office of Finance and Administration
Affiliate, Chemical and Biological Engineering PhD Program
Core, Driskill Graduate Training Program in Life Sciences
Core, Medical Scientist Training Program
Jesse, Sara, Andrew, Abigail, Benjamin and Elizabeth Lurie Professor of Oncology, Lurie Cancer Center
Director (Academic), Lurie Cancer Center

Phone312/908-5250
Emaill-platanias@northwestern.edu

20550 Citations

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Personal profile

Research Interests

chronic leukemias, multiple myeloma, non-hodgkin's lymphoma

Certifications and Licenses

	Medical Oncology
	Internal Medicine

Training Experience

1984	Residency, Hellenic Anticancer Institute
1989	Residency, SUNY/State University of New York Downstate Medical Center
1992	Fellowship, University of Chicago Hospitals

Education/Academic qualification

PhD, University of Patras Medical School

… → 1989

MD, University of Patras Medical School

… → 1983

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Chemical activation Chemical Compounds

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Optimizing Quality of Life in Women Living with Metastatic Breast Cancer: Feasibility and Preliminary Efficacy of a Tailored, eHealth Supportive Oncology Intervention

Platanias, L. C., Penedo, F. J., Victorson, D. E. & Moreno, P. I.

American Cancer Society

1/1/19 → 12/31/21

Project: Research project

grant

quality of life

cancer

funding

scientific journal

Role of TRIM28 in Prostate Cancer

Platanias, L. C. & Fong, K. W.

American Cancer Society

1/1/19 → 12/31/21

Project: Research project

grant

cancer

funding

scientific journal

pilot project

Institutional Research Grant

Platanias, L. C.

American Cancer Society

1/1/19 → 12/31/21

Project: Research project

grant

cancer

funding

scientific journal

pilot project

Adaptation, Design and Implementation of a Patient-Centered, Post-Surgical, Post-Discharge Monitoring System after Gastrointestinal Cancer Surgery

Platanias, L. C. & Merkow, R. P.

American Cancer Society

1/1/19 → 12/31/21

Project: Research project

Gastrointestinal Neoplasms

Research

Neoplasms

Research Personnel

Government Agencies

Characterization of the microbiome in cutaneous T cell lymphoma

Platanias, L. C. & Zhou, A.

American Cancer Society

1/1/19 → 12/31/21

Project: Research project

grant

cancer

funding

scientific journal

pilot project

Research Output 1985 2019

20550 Citations
229 Article
49 Review article
36 Comment/debate
5 Editorial
9 More

Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

Beauchamp, E. M., Abedin, S. M., Radecki, S. G., Fischietti, M., Arslan, A. D., Blyth, G. T., Yang, A., Lantz, C., Nelson, A., Goo, Y. A., Akpan, I., Eklund, E. A., Frankfurt, O., Fish, E. N., Thomas, P. M., Altman, J. K. & Platanias, L. C., Mar 14 2019, In : Blood. 133, 11, p. 1171-1185 15 p.

Research output: Contribution to journal › Article

Cyclin-Dependent Kinase 9

Sirolimus

Acute Myeloid Leukemia

Cytoplasm

Chemical activation

Sirtuin 2–mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses

Kosciuczuk, E. M., Mehrotra, S., Nora Vaz Saleiro, D., Kroczynska, B., Majchrzak-Kita, B., Lisowski, P., Driehaus, C., Rogalska, A., Turner, A., Lienhoop, T., Gius, D. R., Fish, E. N., Vasilopoulos, A. & Platanias, L. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 3, p. 827-837 11 p.

Research output: Contribution to journal › Article

Cyclin-Dependent Kinase 9

Interferon Type I

Sirtuin 2

Interferons

Transcription

Antineoplastic effects of selective CDK9 inhibition with atuveciclib on cancer stem-like cells in triple-negative breast cancer

Brisard, D., Eckerdt, F. D., Marsh, L. A., Blyth, G. T., Jain, S., Cristofanilli, M., Horiuchi, D. & Platanias, L. C., Dec 1 2018, In : Oncotarget. 9, 99, p. 37305-37318 14 p.

Research output: Contribution to journal › Article

Cyclin-Dependent Kinase 9

Triple Negative Breast Neoplasms

Neoplastic Stem Cells

Antineoplastic Agents

Recurrence

Can early intervention with pharmacotherapy reduce the morbidity and mortality of chronic lymphocytic leukemia?

Ma, S. & Platanias, L. C., Jul 24 2018, In : Expert Opinion on Pharmacotherapy. 19, 11, p. 1171-1175 5 p.

Research output: Contribution to journal › Editorial

B-Cell Chronic Lymphocytic Leukemia

Morbidity

Drug Therapy

Mortality

17 Citations (Scopus)

Cell-free DNA and circulating tumor cells: Comprehensive liquid biopsy analysis in advanced breast cancer

Rossi, G., Mu, Z., Rademaker, A. W., Austin, L. K., Strickland, K. S., Costa, R. L. B., Nagy, R. J., Zagonel, V., Taxter, T. J., Behdad, A., Wehbe, F., Platanias, L. C., Gradishar, W. J. & Cristofanilli, M., Feb 1 2018, In : Clinical Cancer Research. 24, 3, p. 560-568 9 p.

Research output: Contribution to journal › Article

Circulating Neoplastic Cells

Breast Neoplasms

Biopsy

DNA

Neoplasms