Leonidas C Platanias

  • 20087 Citations
1985 …2023
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Personal profile

Research Interests

chronic leukemias, multiple myeloma, non-hodgkin's lymphoma

Certifications and Licenses

Internal Medicine
Medical Oncology

Training Experience

1984Residency, Hellenic Anticancer Institute
1989Residency, SUNY/State University of New York Downstate Medical Center
1992Fellowship, University of Chicago Hospitals

Education/Academic qualification

PhD, University of Patras Medical School

… → 1989

MD, University of Patras Medical School

… → 1983

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Grants 2001 2023

Gastrointestinal Neoplasms
Research
Neoplasms
Research Personnel
Government Agencies
grant
cancer
funding
scientific journal
pilot project
grant
cancer
funding
scientific journal
pilot project
grant
cancer
funding
scientific journal
pilot project

Research Output 1985 2019

Sirtuin 2–mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses

Kosciuczuk, E. M., Mehrotra, S., Nora Vaz Saleiro, D., Kroczynska, B., Majchrzak-Kita, B., Lisowski, P., Driehaus, C., Rogalska, A., Turner, A., Lienhoop, T., Gius, D. R., Fish, E. N., Vasilopoulos, A. & Platanias, L. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 3, p. 827-837 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 9
Interferon Type I
Sirtuin 2
Interferons
Transcription

Antineoplastic effects of selective CDK9 inhibition with atuveciclib on cancer stem-like cells in triple-negative breast cancer

Brisard, D., Eckerdt, F. D., Marsh, L. A., Blyth, G. T., Jain, S., Cristofanilli, M., Horiuchi, D. & Platanias, L. C., Dec 1 2018, In : Oncotarget. 9, 99, p. 37305-37318 14 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 9
Triple Negative Breast Neoplasms
Neoplastic Stem Cells
Antineoplastic Agents
Recurrence
B-Cell Chronic Lymphocytic Leukemia
Morbidity
Drug Therapy
Mortality
12 Citations (Scopus)

Cell-free DNA and circulating tumor cells: Comprehensive liquid biopsy analysis in advanced breast cancer

Rossi, G., Mu, Z., Rademaker, A. W., Austin, L. K., Strickland, K. S., Costa, R. L. B., Nagy, R. J., Zagonel, V., Taxter, T. J., Behdad, A., Wehbe, F., Platanias, L. C., Gradishar, W. J. & Cristofanilli, M., Feb 1 2018, In : Clinical Cancer Research. 24, 3, p. 560-568 9 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Breast Neoplasms
Biopsy
DNA
Neoplasms
2 Citations (Scopus)

Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation

Bell, J. B., Eckerdt, F., Dhruv, H. D., Finlay, D., Peng, S., Kim, S., Kroczynska, B., Beauchamp, E. M., Alley, K., Clymer, J., Goldman, S., Cheng, S. Y., James, C. D., Nakano, I., Horbinski, C., Mazar, A. P., Vuori, K., Kumthekar, P., Raizer, J., Berens, M. E. & 1 othersPlatanias, L. C., Jan 1 2018, In : Molecular Cancer Research. 16, 1, p. 32-46 15 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase 1
Protein Biosynthesis
Glioma
Stem Cells
Glioblastoma