Grants per year
Personal profile
Research Interests
rhinosinusitis & drug hypersensitivity; asthma disparities; asthma in the elderly; modification of allergen immunotherapy; immunopathogenesis of allergic diseases including asthma,
Chronic rhinosinusitis
Certifications and Licenses
Occupational Medicine | |
Internal Medicine | |
Clinical & Laboratory Immunology | |
Allergy & Immunology |
Training Experience
1979 | Residency, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital) |
1981 | Fellowship, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital) |
Education/Academic qualification
Medicine, MD, Northwestern University
… → 1976
MD, Medicine, Northwestern University
… → 1976
Research interests keywords
- Allergies
- Asthma
- Food Allergy
- Immunodeficiency
- Respiratory Diseases
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Collaborations and top research areas from the last five years
Grants
- 18 Finished
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New Approaches for Empowering Studies of Asthma in Populations of African Descent
Avila, P. C. (PD/PI), Grammer III, L. C. (Co-PD/PI) & Grammer III, L. C. (Co-Investigator)
Johns Hopkins University, National Heart, Lung, and Blood Institute
9/28/11 → 6/30/15
Project: Research project
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Role of Epithelium in Immunity, Inflammation and Disease
Schleimer, R. P. (PD/PI), Grammer III, L. C. (Co-PD/PI), Kato, A. (Co-PD/PI), Kern, R. C. (Co-PD/PI) & Peters, A. T. (Co-PD/PI)
National Heart, Lung, and Blood Institute
7/12/10 → 4/30/14
Project: Research project
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Experimental Therapy for Peanut Allergy with Novel Peanut-Human Fusion Protein
Grammer III, L. C. (Co-Investigator)
National Institute of Allergy and Infectious Diseases
3/1/10 → 2/29/12
Project: Research project
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Novel Plant-Human Fusion Proteins Block Peanut Allergy
Grammer III, L. C. (Co-Investigator) & Schleimer, R. P. (Co-Investigator)
Food Allergy & Anaphylaxis Network
2/1/09 → 1/31/10
Project: Research project
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Novel Plant-Human Fusion Proteins Block Peanut Allergy
Grammer III, L. C. (Co-Investigator) & Schleimer, R. P. (Co-Investigator)
Food Allergy & Anaphylaxis Network
2/1/09 → 1/31/10
Project: Research project
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5-HTP inhibits eosinophilia via intracellular endothelial 5-HTRs; SNPs in 5-HTRs associate with asthmatic lung function
Walker, M. T., Bloodworth, J. C., Kountz, T. S., McCarty, S. L., Green, J. E., Ferrie, R. P., Campbell, J. A., Averill, S. H., Beckman, K. B., Grammer, L. C., Eng, C., Avila, P. C., Farber, H. J., Rodriguez-Cintron, W., Rodriguez-Santana, J. R., Serebrisky, D., Thyne, S. M., Seibold, M. A., Burchard, E. G. & Kumar, R. & 1 others, , 2024, In: Frontiers in Allergy. 5, 1385168.Research output: Contribution to journal › Article › peer-review
Open Access -
Single cell RNA sequencing of human eosinophils from nasal polyps reveals eosinophil heterogeneity in chronic rhinosinusitis tissue
Iwasaki, N., Poposki, J. A., Oka, A., Kidoguchi, M., Klingler, A. I., Suh, L. A., Bai, J., Stevens, W. W., Peters, A. T., Grammer, L. C., Welch, K. C., Smith, S. S., Conley, D. B., Schleimer, R. P., Kern, R. C., Bochner, B. S., Tan, B. K. & Kato, A., 2024, (Accepted/In press) In: Journal of Allergy and Clinical Immunology. 154, 4, p. 952-964 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Evidence that oncostatin M synergizes with IL-4 signaling to induce TSLP expression in chronic rhinosinusitis with nasal polyps
Wang, B. F., Cao, P. P., Norton, J. E., Poposki, J. A., Klingler, A. I., Suh, L. A., Carter, R., Huang, J. H., Bai, J., Stevens, W. W., Tan, B. K., Peters, A. T., Grammer, L. C., Conley, D. B., Welch, K. C., Liu, Z., Kern, R. C., Kato, A. & Schleimer, R. P., May 2023, In: Journal of Allergy and Clinical Immunology. 151, 5, p. 1379-1390.e11Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Apr 2023, In: Science Advances. 9, 17, eabm4945.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Anti-phospholipid antibodies are elevated and functionally active in chronic rhinosinusitis with nasal polyps
Eide, J. G., Wu, J., Stevens, W. W., Bai, J., Hou, S., Huang, J. H., Rosenberg, J., Utz, P., Shintani-Smith, S., Conley, D. B., Welch, K. C., Kern, R. C., Hulse, K. E., Peters, A. T., Grammer, L. C., Zhao, M., Lindholm, P., Schleimer, R. P. & Tan, B. K., Aug 2022, In: Clinical and Experimental Allergy. 52, 8, p. 954-964 11 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations