Grants per year
Personal profile
Research Interests
The clinical focus of Dr. Hargrove's work is to apply promising control approaches to improve the control of prosthetic limbs and exoskeletons.
Levi J. Hargrove, PhD, P.Eng, received his MScE and PhD in Electrical Engineering from the University of New Brunswick (2005, 2008). He is currently the Director of Center for Bionic Medicine at the Shirley Ryan AbilityLab and an Associate Professor in the Departments of Physical Medicine & Rehabilitation and the McCormick School of Engineering at Northwestern University. A major goal of his research is to develop clinically realizable myoelectric control systems that can be made available to persons with limb loss in the near future. His research addresses all levels of amputation and has been published in the Journal of the American Medical Association and the New England Journal of Medicine and multiple patents. Key projects include the development of advanced and adaptive control systems for prosthetic legs, improving control of robotic hand prostheses, and intramuscular EMG signal processing. In 2012, Dr. Hargrove co-founded Coapt LLC, a company which provides the first and only intuitive pattern recognition control systems for bionic arms.
The academic focus of Dr. Hargrove's work is to apply machine learning and pattern recognition techniques to improve control of robotic assistive devices for individuals with physical disabilities. Promising approaches are implemented on embedded systems and tested on physical hardwre with users in-the-loop providing feedback.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Biomedical Engineering, University of New Brunswick
… → 2008
Research interests keywords
- Amputation
- Electrophysiology
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Collaborations and top research areas from the last five years
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Pathophysiology and Rehabilitation of Neural Dysfunction
Hargrove, L. J. (PD/PI), Perreault, E. (PD/PI), Perreault, E. (PD/PI), Perreault, E. (PD/PI), Perreault, E. (Co-PD/PI), Hargrove, L. J. (Other), Hargrove, L. J. (Other), Hargrove, L. J. (Other), Miller, L. E. (Other), Miller, L. E. (Other), Roth, E. J. (Other) & Roth, E. J. (Other)
National Institute of Child Health and Human Development
5/1/22 → 4/30/27
Project: Research project
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Intuitive Control of a Hybrid Prosthetic Leg During Ambulation
Hargrove, L. J. (PD/PI)
Rehabilitation Institute of Chicago, National Institute of Child Health and Human Development
1/1/21 → 12/31/21
Project: Research project
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Intuitive Control of a Hybrid Prosthetic Leg During Ambulation
Hargrove, L. J. (PD/PI)
Shirley Ryan AbilityLab, National Institute of Child Health & Human Development (NICHD)
9/20/18 → 6/30/23
Project: Research project
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Flexible Epidermal Electrodes for Intuitive Control of Powered Arm and Leg Protheses
Hargrove, L. J. (PD/PI)
Shirley Ryan AbilityLab, Department of Defense
9/15/18 → 9/14/21
Project: Research project
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Dry EEG Measurement of P3 to Evaluate Cognitive Load During Sitting, Standing, and Walking
Swerdloff, M. M. & Hargrove, L. J., 2025, Biosystems and Biorobotics. Springer Science and Business Media Deutschland GmbH, p. 170-173 4 p. (Biosystems and Biorobotics; vol. 34).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Human-in-the-Loop Myoelectric Pattern Recognition Control of an Arm-Support Robot to Improve Reaching in Stroke Survivors
Kopke, J. V., Ellis, M. D. & Hargrove, L. J., 2025, In: IEEE Transactions on Neural Systems and Rehabilitation Engineering. 33, p. 1108-1117 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Measuring metabolic energy expenditure with short duration walking tests for individuals with lower limb amputation
Ikeda, A. J., Smit, J. A., Simon, A. M., Anarwala, S. J. & Hargrove, L. J., Mar 2025, In: PloS one. 20, 3 March, e0320384.Research output: Contribution to journal › Article › peer-review
Open Access -
Predicting Phantom Limb Pain Treatment Response in Individuals with Limb Loss
Hargrove, L. J., Turner, K. L., Ikeda, A., Lock, B. A. & Wright, Z. A., 2025, Biosystems and Biorobotics. Springer Science and Business Media Deutschland GmbH, p. 118-122 5 p. (Biosystems and Biorobotics; vol. 31).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Biomimetic versus arbitrary motor control strategies for bionic hand skill learning
Schone, H. R., Udeozor, M., Moninghoff, M., Rispoli, B., Vandersea, J., Lock, B., Hargrove, L., Makin, T. R. & Baker, C. I., Jun 2024, In: Nature human behaviour. 8, 6, p. 1108-1123 16 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations
Datasets
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Data from: Adaptation to random and systematic errors: Comparison of amputee and non-amputee control interfaces with varying levels of process noise
Johnson, R. E. (Creator), Kording, K. P. (Creator), Hargrove, L. J. (Creator) & Sensinger, J. W. (Creator), Dryad, Jan 31 2018
DOI: 10.5061/dryad.b2p3j, https://datadryad.org/dataset/doi:10.5061/dryad.b2p3j
Dataset
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Data from: EMG versus torque control of human-machine systems: equalizing control signal variability does not equalize error or uncertainty
Johnson, R. E. (Creator), Kording, K. P. (Creator), Hargrove, L. J. (Creator) & Sensinger, J. W. (Creator), Dryad, Jul 27 2017
DOI: 10.5061/dryad.80150, https://datadryad.org/dataset/doi:10.5061/dryad.80150
Dataset
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Data from: Evidence for a time-invariant phase variable in human ankle control
Gregg, R. D. (Creator), Rouse, E. J. (Creator), Hargrove, L. J. (Creator) & Sensinger, J. W. (Creator), Dryad, Jan 28 2015
DOI: 10.5061/dryad.rm505, https://datadryad.org/dataset/doi:10.5061/dryad.rm505
Dataset
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Decoding the grasping intention from electromyography during reaching motions
Batzianoulis, I. (Creator), Krausz, N. E. (Creator), Simon, A. M. (Creator), Hargrove, L. (Creator) & Billard, A. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.c.4144982, https://figshare.com/collections/Decoding_the_grasping_intention_from_electromyography_during_reaching_motions/4144982
Dataset
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Data from: Evidence for a time-invariant phase variable in human ankle control
Gregg, R. D. (Contributor), Rouse, E. J. (Contributor), Hargrove, L. J. (Contributor) & Sensinger, J. W. (Contributor), ZENODO, Jan 28 2015
DOI: 10.5061/dryad.rm505, https://zenodo.org/records/4940918
Dataset