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Lewis J Smith

 https://orcid.org/0000-0002-4728-1562
  • Source: Scopus
1977 …2021

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Personal profile

Research Interests

My current research interests include the role of diet in asthma pathogenesis, novel treatments for asthma and COPD, and the development of novel clinical research study designs to improve the translation of clinical research results into better health outcomes.

Certifications and Licenses

Internal Medicine
Pulmonary Disease

Training Experience

1974Internship, Strong Memorial Hospital
1976Residency, Strong Memorial Hospital
1978Fellowship, Boston City Hospital

Education/Academic qualification

MD, University of Rochester

… → 1973

Research interests

  • Asthma
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Clinical Research
  • Drugs (clinical pharmacology)

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Network

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View all 65 grants

  • Geography, generalisability, and susceptibility in clinical trials

    Clougherty, J. E., Kinnee, E. J., Cardet, J. C., Mauger, D., Bacharier, L., Beigelman, A., Blake, K. V., Cabana, M. D., Castro, M., Chmiel, J. F., Covar, R., Fitzpatrick, A., Gaffin, J. M., Gentile, D., Israel, E., Jackson, D. J., Kraft, M., Krishnan, J. A., Kumar, H. V., Lang, J. E. & 21 others, Lazarus, S. C., Lemanske, R. F., Lima, J., Martinez, F. D., Morgan, W., Moy, J., Myers, R., Naureckas, E. T., Ortega, V. E., Peters, S. P., Phipatanakul, W., Pongracic, J. A., Ross, K., Sheehan, W. J., Smith, L. J., Solway, J., Sorkness, C. A., Wechsler, M. E., Wenzel, S., White, S. R. & Holguin, F., Apr 2021, In: The Lancet Respiratory Medicine. 9, 4, p. 330-332 3 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    1 Scopus citations

  • PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment

    Israel, E., Denlinger, L. C., Bacharier, L. B., LaVange, L. M., Moore, W. C., Peters, M. C., Georas, S. N., Wright, R. J., Mauger, D. T., Noel, P., Akuthota, P., Bach, J., Bleecker, E. R., Cardet, J. C., Carr, T. F., Castro, M., Cinelli, A., Comhair, S. A. A., Covar, R. A., Alexander, L. C. & 37 others, DiMango, E. A., Erzurum, S. C., Fahy, J. V., Fajt, M. L., Gaston, B. M., Hoffman, E. A., Holguin, F., Jackson, D. J., Jain, S., Jarjour, N. N., Ji, Y., Kenyon, N. J., Kosorok, M. R., Kraft, M., Krishnan, J. A., Kumar, R., Liu, A. H., Liu, M. C., Ly, N. P., Marquis, M. A., Martinez, F. D., Moy, J. N., O'Neal, W. K., Ortega, V. E., Peden, D. B., Phipatanakul, W., Ross, K., Smith, L. J., Szefler, S. J., Teague, W. G., Tulchinsky, A. F., Vijayanand, P., Wechsler, M. E., Wenzel, S. E., White, S. R., Zeki, A. A. & Ivanova, A., May 2021, In: Journal of Allergy and Clinical Immunology. 147, 5, p. 1594-1601 8 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Association of Nonobstructive Chronic Bronchitis with Respiratory Health Outcomes in Adults

    Balte, P. P., Chaves, P. H. M., Couper, D. J., Enright, P., Jacobs, D. R., Kalhan, R., Kronmal, R. A., Loehr, L. R., London, S. J., Newman, A. B., O'Connor, G. T., Schwartz, J. E., Smith, B. M., Smith, L. J., White, W. B., Yende, S. & Oelsner, E. C., May 2020, In: JAMA internal medicine. 180, 5, p. 676-686 11 p.

    Research output: Contribution to journal › Article › peer-review

    5 Scopus citations

  • Lung function decline in former smokers and low-intensity current smokers: a secondary data analysis of the NHLBI Pooled Cohorts Study

    Oelsner, E. C., Balte, P. P., Bhatt, S. P., Cassano, P. A., Couper, D., Folsom, A. R., Freedman, N. D., Jacobs, D. R., Kalhan, R., Mathew, A. R., Kronmal, R. A., Loehr, L. R., London, S. J., Newman, A. B., O'Connor, G. T., Schwartz, J. E., Smith, L. J., White, W. B. & Yende, S., Jan 2020, In: The Lancet Respiratory Medicine. 8, 1, p. 34-44 11 p.

    Research output: Contribution to journal › Article › peer-review

    27 Scopus citations

  • The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations

    Ivanova, A., Israel, E., LaVange, L. M., Peters, M. C., Denlinger, L. C., Moore, W. C., Bacharier, L. B., Marquis, M. A., Gotman, N. M., Kosorok, M. R., Tomlinson, C., Mauger, D. T., Georas, S. N., Wright, R. J., Noel, P., Rosner, G. L., Akuthota, P., Billheimer, D., Bleecker, E. R., Cardet, J. C. & 23 others, Castro, M., DiMango, E. A., Erzurum, S. C., Fahy, J. V., Fajt, M. L., Gaston, B. M., Holguin, F., Jain, S., Kenyon, N. J., Krishnan, J. A., Kraft, M., Kumar, R., Liu, M. C., Ly, N. P., Moy, J. N., Phipatanakul, W., Ross, K., Smith, L. J., Szefler, S. J., Teague, W. G., Wechsler, M. E., Wenzel, S. E. & White, S. R., 2020, In: Journal of Biopharmaceutical Statistics. 30, 6, p. 1026-1037 12 p.

    Research output: Contribution to journal › Article › peer-review

    5 Scopus citations
View all 158 research output