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Research Output 2000 2019

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2019

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P. C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S. J. & 37 others, Bressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M. F., Rotter, J. I., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D. I., Bell, J. T., Demirkan, A. & van Duijn, C. M., Dec 1 2019, In : Nature communications. 10, 1, 2581.

Research output: Contribution to journalArticle

Open Access
homeostasis
insulin
methylation
Methylation
DNA Methylation

A peripheral blood DNA methylation signature of hepatic fat reveals a potential causal pathway for nonalcoholic fatty liver disease

Ma, J., Nano, J., Ding, J., Zheng, Y., Hennein, R., Liu, C., Speliotes, E. K., Huan, T., Song, C., Mendelson, M. M., Joehanes, R., Long, M. T., Liang, L., Smith, J. A., Reynolds, L. M., Ghanbari, M., Muka, T., Van Meurs, J. B. J., Alferink, L. J. M., Franco, O. H. & 17 others, Dehghan, A., Ratliff, S., Zhao, W., Bielak, L., Kardia, S. L. R., Peyser, P. A., Ning, H., VanWagner, L. B., Lloyd-Jones, D. M., Carr, J. J., Greenland, P., Lichtenstein, A. H., Hu, F. B., Liu, Y., Hou, L., Murad, S. D. & Levy, D., Jan 1 2019, In : Diabetes. 68, 5, p. 1073-1083 11 p.

Research output: Contribution to journalArticle

DNA Methylation
Fats
Liver
Type 2 Diabetes Mellitus
Mendelian Randomization Analysis

Association of clinical outcomes in metastatic breast cancer patients with circulating tumour cell and circulating cell-free DNA

Ye, Z., Wang, C., Wan, S., Mu, Z., Zhang, Z., Abu-Khalaf, M. M., Fellin, F. M., Silver, D. P., Neupane, M., Jaslow, R. J., Bhattacharya, S., Tsangaris, T. N., Chervoneva, I., Berger, A., Austin, L., Palazzo, J. P., Myers, R. E., Pancholy, N., Toorkey, D., Yao, K. & 10 others, Krall, M., Li, X., Chen, X., Fu, X., Xing, J., Hou, L., Wei, Q., Li, B., Cristofanilli, M. & Yang, H., Jan 1 2019, In : European Journal of Cancer. 106, p. 133-143 11 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Breast Neoplasms
DNA
Disease-Free Survival
Survival

DASH diet and prevalent metabolic syndrome in the Hispanic Community Health Study/Study of Latinos

Joyce, B. T., Wu, D., Hou, L., Dai, Q., Castaneda, S. F., Gallo, L. C., Talavera, G. A., Sotres-Alvarez, D., Van Horn, L., Beasley, J. M., Khambaty, T., Elfassy, T., Zeng, D., Mattei, J., Corsino, L. & Daviglus, M. L., Sep 1 2019, In : Preventive Medicine Reports. 15, 100950.

Research output: Contribution to journalArticle

Open Access
Hispanic Americans
Diet
Hypertension
Health
Blood Pressure
11 Citations (Scopus)

DNA methylation GrimAge strongly predicts lifespan and healthspan

Lu, A. T., Quach, A., Wilson, J. G., Reiner, A. P., Aviv, A., Raj, K., Hou, L., Baccarelli, A. A., Li, Y., Stewart, J. D., Whitsel, E. A., Assimes, T. L., Ferrucci, L. & Horvath, S., Jan 1 2019, In : Aging. 11, 2, p. 303-327 25 p.

Research output: Contribution to journalArticle

DNA Methylation
Epigenomics
Biomarkers
Plasminogen Activator Inhibitor 1
Comorbidity
3 Citations (Scopus)

Impacts of air pollution, temperature, and relative humidity on leukocyte distribution: An epigenetic perspective

Gao, X., Colicino, E., Shen, J., Kioumourtzoglou, M. A., Just, A. C., Nwanaji-Enwerem, J. C., Coull, B., Lin, X., Vokonas, P., Zheng, Y., Hou, L., Schwartz, J. & Baccarelli, A. A., May 1 2019, In : Environment International. 126, p. 395-405 11 p.

Research output: Contribution to journalArticle

Open Access
relative humidity
atmospheric pollution
blood
pollution exposure
methylation

IP3R and RyR channels are involved in traffic-related PM2.5-induced disorders of calcium homeostasis

Zhao, H., Tong, G., Liu, J., Wang, J., Zhang, H., Bai, J., Hou, L. & Zhang, Z., May 1 2019, In : Toxicology and Industrial Health. 35, 5, p. 339-348 10 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Jurkat Cells
T-cells
Inositol 1,4,5-Trisphosphate Receptors
Homeostasis

Lactation intensity and duration to postpartum diabetes and prediabetes risk in women with gestational diabetes

Shen, Y., Leng, J., Li, W., Zhang, S., Liu, H., Shao, P., Wang, P., Wang, L., Tian, H., Zhang, C., Yang, X., Yu, Z., Hou, L., Tuomilehto, J. & Hu, G., Mar 1 2019, In : Diabetes/Metabolism Research and Reviews. 35, 3, e3115.

Research output: Contribution to journalArticle

Open Access
Prediabetic State
Gestational Diabetes
Lactation
Postpartum Period
Glucose Tolerance Test

Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation

Gondalia, R., Baldassari, A., Holliday, K. M., Justice, A. E., Méndez-Giráldez, R., Stewart, J. D., Liao, D., Yanosky, J. D., Brennan, K. J. M., Engel, S. M., Jordahl, K. M., Kennedy, E., Ward-Caviness, C. K., Wolf, K., Waldenberger, M., Cyrys, J., Bhatti, P., Horvath, S., Assimes, T. L., Pankow, J. S. & 10 others, Demerath, E. W., Guan, W., Fornage, M., Bressler, J., North, K. E., Conneely, K. N., Li, Y., Hou, L., Baccarelli, A. A. & Whitsel, E. A., Jan 1 2019, In : Environment International. 104723.

Research output: Contribution to journalArticle

Open Access
methylation
particulate matter
atmospheric pollution
DNA
subpopulation

Optimism is not associated with two indicators of DNA methylation aging

Kim, E. S., Fong, K., Lee, L., Spiro, A., Schwartz, J., Whitsel, E., Horvath, S., Wang, C., Hou, L., Baccarelli, A. A., Li, Y., Stewart, J., Manson, J. A. E., Grodstein, F., DeMeo, D. L. & Kubzansky, L. D., Jan 1 2019, In : Aging. 11, 14, p. 4970-4989 20 p.

Research output: Contribution to journalArticle

DNA Methylation
Cell Aging
Women's Health
Confidence Intervals
Epigenomics
1 Citation (Scopus)

Predictors of urinary phthalate biomarker concentrations in postmenopausal women

Reeves, K. W., Santana, M. D., Manson, J. A. E., Hankinson, S. E., Zoeller, R. T., Bigelow, C., Hou, L., Wactawski-Wende, J., Liu, S., Tinker, L. & Calafat, A. M., Feb 1 2019, In : Environmental Research. p. 122-130 9 p.

Research output: Contribution to journalArticle

phthalate
Biomarkers
biomarker
Metabolites
metabolite
2 Citations (Scopus)

Racial/Ethnic differences in 25-hydroxy vitamin D and parathyroid hormone levels and cardiovascular disease risk among postmenopausal women

Zhang, X., Tu, W., Manson, J. E., Tinker, L., Liu, S., Cauley, J. A., Qi, L., Mouton, C., Martin, L. W., Hou, L. & Song, Y., Jan 1 2019, In : Journal of the American Heart Association. 8, 4, e011021.

Research output: Contribution to journalArticle

Parathyroid Hormone
Vitamin D
Cardiovascular Diseases
Proteins
Parathyroid Diseases

Smoking-related DNA methylation is associated with DNA methylation phenotypic age acceleration: The veterans affairs normative aging study

Yang, Y., Gao, X., Just, A. C., Colicino, E., Wang, C., Coull, B. A., Hou, L., Zheng, Y., Vokonas, P., Schwartz, J. & Baccarelli, A. A., Jul 1 2019, In : International journal of environmental research and public health. 16, 13, 2356.

Research output: Contribution to journalArticle

Open Access
Veterans
DNA Methylation
Smoking
Epigenomics
Chronic Disease
2018
1 Citation (Scopus)

Accelerated DNA methylation age and the use of antihypertensive medication among older adults

Gao, X., Colicino, E., Shen, J., Just, A. C., Nwanaji-Enwerem, J. C., Coull, B., Lin, X., Vokonas, P., Zheng, Y., Hou, L., Schwartz, J. & Baccarelli, A. A., Nov 1 2018, In : Aging. 10, 11, p. 3210-3228 19 p.

Research output: Contribution to journalArticle

DNA Methylation
Antihypertensive Agents
Hypertension
Interviews
Physicians

Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction

Ward-Caviness, C. K., Agha, G., Chen, B. H., Pfeiffer, L., Wilson, R., Wolf, P., Gieger, C., Schwartz, J., Vokonas, P. S., Hou, L., Just, A. C., Bandinelli, S., Hernandez, D. G., Singleton, A. B., Prokisch, H., Meitinger, T., Kastenmüller, G., Ferrucci, L., Baccarelli, A. A., Waldenberger, M. & 1 others, Peters, A., Dec 27 2018, In : Clinical Epigenetics. 10, 1, 161.

Research output: Contribution to journalArticle

DNA Methylation
Epigenomics
Leukocytes
Myocardial Infarction
Dermatoglyphics
72 Citations (Scopus)

An epigenetic biomarker of aging for lifespan and healthspan

Levine, M. E., Lu, A. T., Quach, A., Chen, B. H., Assimes, T. L., Bandinelli, S., Hou, L., Baccarelli, A. A., Stewart, J. D., Li, Y., Whitsel, E. A., Wilson, J. G., Reiner1, A. P., Aviv1, A., Lohman, K., Liu, Y., Ferrucci, L. & Horvath, S., Apr 1 2018, In : Aging. 10, 4, p. 573-591 19 p.

Research output: Contribution to journalArticle

Epigenomics
Biomarkers
Interferons
Transcriptional Activation
DNA Damage
Nigeria
Early Detection of Cancer
Uterine Cervical Neoplasms
HIV
Referral and Consultation
6 Citations (Scopus)
Telomere
Observational Studies
Meta-Analysis
Body Mass Index
Cross-Sectional Studies

DNA methylation in blood as a mediator of the association of mid-childhood body mass index with cardio-metabolic risk score in early adolescence

Huang, J. V., Cardenas, A., Colicino, E., Schooling, C. M., Rifas-Shiman, S. L., Agha, G., Zheng, Y., Hou, L., Just, A. C., Litonjua, A. A., DeMeo, D. L., Lin, X., Oken, E., Hivert, M. F. & Baccarelli, A. A., Nov 2 2018, In : Epigenetics. 13, 10-11, p. 1072-1087 16 p.

Research output: Contribution to journalArticle

DNA Methylation
Body Mass Index
Epigenomics
Sample Size
Leukocytes
4 Citations (Scopus)

DNA methylation of telomere-related genes and cancer risk

Joyce, B. T., Zheng, Y., Nannini, D., Zhang, Z., Liu, L., Gao, T., Kocherginsky, M., Murphy, R. L., Yang, H., Achenbach, C. J., Roberts, L. R., Hoxha, M., Shen, J., Vokonas, P., Schwartz, J., Baccarelli, A. & Hou, L., Aug 1 2018, In : Cancer Prevention Research. 11, 8, p. 511-522 12 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Telomere
DNA Methylation
Neoplasms
Leukocytes
8 Citations (Scopus)

DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: Meta-analysis of multiethnic epigenome-wide studies

Jovanova, O. S., Nedeljkovic, I., Spieler, D., Walker, R. M., Liu, C., Luciano, M., Bressler, J., Brody, J., Drake, A. J., Evans, K. L., Gondalia, R., Kunze, S., Kuhnel, B., Lahti, J., Lemaitre, R. N., Marioni, R. E., Swenson, B., Himali, J. J., Wu, H., Li, Y. & 29 others, McRae, A. F., Russ, T. C., Stewart, J., Wang, Z., Zhang, G., Ladwig, K. H., Uitterlinden, A. G., Guo, X., Peters, A., Räikkönen, K., Starr, J. M., Waldenberger, M., Wray, N. R., Whitsel, E. A., Sotoodehnia, N., Seshadri, S., Porteous, D. J., Van Meurs, J., Mosley, T. H., McIntosh, A. M., Mendelson, M. M., Levy, D., Hou, L., Eriksson, J. G., Fornage, M., Deary, I. J., Baccarelli, A., Tiemeier, H. & Amin, N., Sep 1 2018, In : JAMA Psychiatry. 75, 9, p. 949-959 11 p.

Research output: Contribution to journalArticle

DNA Methylation
Meta-Analysis
Depression
Epigenomics
Methylation
25 Citations (Scopus)

Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

Horvath, S., Oshima, J., Martin, G. M., Lu, A. T., Quach, A., Cohen, H., Felton, S., Matsuyama, M., Lowe, D., Kabacik, S., Wilson, J. G., Reiner, A. P., Maierhofer, A., Flunkert, J., Aviv, A., Hou, L., Baccarelli, A. A., Li, Y., Stewart, J. D., Whitsel, E. A. & 3 others, Ferrucci, L., Matsuyama, S. & Raj, K., Jul 1 2018, In : Aging. 10, 7, p. 1758-1775 18 p.

Research output: Contribution to journalArticle

Progeria
DNA Methylation
Epigenomics
Blood Cells
Biomarkers
1 Citation (Scopus)

Folate deficiency and aberrant DNA methylation and expression of FHIT gene were associated with cervical pathogenesis

Li, Q., Ding, L., Jing, N., Liu, C., Yang, Z., Chen, F., Hou, L. & Wang, J., Feb 1 2018, In : Oncology Letters. 15, 2, p. 1963-1972 10 p.

Research output: Contribution to journalArticle

DNA Methylation
Folic Acid
Histidine
Methylation
Genes
20 Citations (Scopus)

GWAS of epigenetic aging rates in blood reveals a critical role for TERT

Lu, A. T., Xue, L., Salfati, E. L., Chen, B. H., Ferrucci, L., Levy, D., Joehanes, R., Murabito, J. M., Kiel, D. P., Tsai, P. C., Yet, I., Bell, J. T., Mangino, M., Tanaka, T., McRae, A. F., Marioni, R. E., Visscher, P. M., Wray, N. R., Deary, I. J., Levine, M. E. & 19 others, Quach, A., Assimes, T., Tsao, P. S., Absher, D., Stewart, J. D., Li, Y., Reiner, A. P., Hou, L., Baccarelli, A. A., Whitsel, E. A., Aviv, A., Cardona, A., Day, F. R., Wareham, N. J., Perry, J. R. B., Ong, K. K., Raj, K., Lunetta, K. L. & Horvath, S., Dec 1 2018, In : Nature communications. 9, 1, 387.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Telomerase
Epigenomics
genes
blood
2 Citations (Scopus)

Intakes of magnesium, calcium and risk of fatty liver disease and prediabetes

Li, W., Zhu, X., Song, Y., Fan, L., Wu, L., Kabagambe, E. K., Hou, L., Shrubsole, M. J., Liu, J. & Dai, Q., Aug 1 2018, In : Victorian Literature and Culture. 21, 11, p. 2088-2095 8 p.

Research output: Contribution to journalArticle

Disease
alcohol
Intake
Calcium
Magnesium
1 Citation (Scopus)

Maternal gestational diabetes and different indicators of childhood obesity: A large study

Wang, J., Wang, L., Liu, H., Zhang, S., Leng, J., Li, W., Zhang, T., Li, N., Li, W., Baccarelli, A. A., Hou, L. & Hu, G., Jan 1 2018, In : Endocrine Connections. 7, 12, p. 1464-1471 8 p.

Research output: Contribution to journalArticle

Open Access
Gestational Diabetes
Pediatric Obesity
Mothers
Waist Circumference
Pregnancy
2 Citations (Scopus)

Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts

Carmona, J. J., Barfield, R. T., Panni, T., Nwanaji-Enwerem, J. C., Just, A. C., Hutchinson, J. N., Colicino, E., Karrasch, S., Wahl, S., Kunze, S., Jafari, N., Zheng, Y., Hou, L., DeMeo, D. L., Litonjua, A. A., Vokonas, P. S., Peters, A., Lin, X., Schwartz, J., Schulz, H. & 1 others, Baccarelli, A. A., Nov 2 2018, In : Epigenetics. 13, 10-11, p. 1039-1055 17 p.

Research output: Contribution to journalArticle

DNA Methylation
Lung
Epigenomics
Biomarkers
Vulnerable Populations
2 Citations (Scopus)

MiRNA-processing gene methylation and cancer risk

Joyce, B. T., Zheng, Y., Zhang, Z., Liu, L., Kocherginsky, M., Murphy, R. L., Achenbach, C. J., Musa, J., Wehbe, F., Just, A., Shen, J., Vokonas, P., Schwartz, J., Baccarelli, A. A. & Hou, L., May 1 2018, In : Cancer Epidemiology Biomarkers and Prevention. 27, 5, p. 550-557 8 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Methylation
MicroRNAs
Neoplasms
DNA Methylation

Neurotrophins and cholinergic enzyme regulated by calpain-2: New insights into neuronal apoptosis induced by polybrominated diphenyl ether-153

Zhang, H., Yang, X., Zhang, H., Li, X., Zhang, Z., Hou, L., Wang, Z., Niu, Q. & Wang, T., Jul 1 2018, In : Toxicology Letters. 291, p. 29-38 10 p.

Research output: Contribution to journalArticle

Halogenated Diphenyl Ethers
Calpain
Nerve Growth Factors
Cholinergic Agents
Apoptosis
3 Citations (Scopus)

Promoter methylation of PGC1A and PGC1B predicts cancer incidence in a veteran cohort

Kresovich, J. K., Joyce, B. T., Gao, T., Zheng, Y., Zhang, Z., Achenbach, C. J., Murphy, R. L., Just, A. C., Shen, J., Yang, H., Vokonas, P., Schwartz, J., Baccarelli, A. A. & Hou, L., Jun 1 2018, In : Epigenomics. 10, 6, p. 733-743 11 p.

Research output: Contribution to journalArticle

Telomere
Veterans
Methylation
Incidence
Leukocytes
1 Citation (Scopus)

The effect of genetic variants on the relationship between statins and breast cancer in postmenopausal women in the women’s health initiative observational study

Bock, C. H., Jay, A. M., Dyson, G., Beebe-Dimmer, J. L., Cote, M. L., Hou, L., Howard, B. V., Desai, P., Purrington, K., Prentice, R. & Simon, M. S., Oct 24 2018, In : Breast Cancer Research and Treatment. 167, 3, p. 741-749 9 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Women's Health
Observational Studies
Breast Neoplasms
Single Nucleotide Polymorphism

The Inflammatory Potential of Dietary Manganese in a Cohort of Elderly Men

Kresovich, J. K., Bulka, C. M., Joyce, B. T., Vokonas, P. S., Schwartz, J., Baccarelli, A. A., Hibler, E. A. & Hou, L., May 1 2018, In : Biological Trace Element Research. 183, 1, p. 49-57 9 p.

Research output: Contribution to journalArticle

Manganese
Biomarkers
Methylation
Genes
DNA Methylation
4 Citations (Scopus)

The modifying effect of kidney function on the association of cadmium exposure with blood pressure and cardiovascular mortality: NHANES 1999–2010

Gao, Y., Zhu, X., Shrubsole, M. J., Fan, L., Xia, Z., Harris, R. C., Hou, L. & Dai, Q., Aug 15 2018, In : Toxicology and Applied Pharmacology. 353, p. 15-22 8 p.

Research output: Contribution to journalArticle

Nutrition Surveys
Blood pressure
Cadmium
Blood Pressure
Kidney
2017
9 Citations (Scopus)

A longitudinal study of DNA methylation as a potential mediator of age-related diabetes risk

Grant, C. D., Jafari, N., Hou, L., Li, Y., Stewart, J. D., Zhang, G., Lamichhane, A., Manson, J. A. E., Baccarelli, A. A., Whitsel, E. A. & Conneely, K. N., Dec 1 2017, In : GeroScience. 39, 5-6, p. 475-489 15 p.

Research output: Contribution to journalArticle

DNA Methylation
Longitudinal Studies
Phenotype
Methylation
Waist Circumference
1 Citation (Scopus)

Association between hypertensive disorders of pregnancy and the risk of postpartum hypertension: A cohort study in women with gestational diabetes

Wang, L., Leng, J., Liu, H., Zhang, S., Wang, J., Li, W., Li, W., Li, N., Zhang, T., Baccarelli, A. A., Hou, L., Yang, X., Yu, Z. & Hu, G., Nov 1 2017, In : Journal of human hypertension. 31, 11, p. 725-730 6 p.

Research output: Contribution to journalArticle

Gestational Diabetes
Postpartum Period
Cohort Studies
Hypertension
Pregnancy
4 Citations (Scopus)

Association of Accelerometer-Measured Physical Activity with Leukocyte Telomere Length among Older Women

Shadyab, A. H., Lamonte, M. J., Kooperberg, C., Reiner, A. P., Carty, C. L., Manini, T. M., Hou, L., Di, C. & Lacroix, A. Z., Nov 1 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 11, p. 1532-1537 6 p.

Research output: Contribution to journalArticle

Telomere
Leukocytes
Exercise
Light
Linear Models
6 Citations (Scopus)

Association of air particulate pollution with bone loss over time and bone fracture risk: analysis of data from two independent studies

Prada, D., Zhong, J., Colicino, E., Zanobetti, A., Schwartz, J., Dagincourt, N., Fang, S. C., Kloog, I., Zmuda, J. M., Holick, M., Herrera, L. A., Hou, L., Dominici, F., Bartali, B. & Baccarelli, A. A., Nov 1 2017, In : The Lancet Planetary Health. 1, 8, p. e337-e347

Research output: Contribution to journalArticle

Soot
Bone Fractures
Air Pollution
air pollution
Particulate Matter
13 Citations (Scopus)

Associations between long-term exposure to PM2.5 component species and blood DNA methylation age in the elderlyThe VA normative aging study

Nwanaji-Enwerem, J. C., Dai, L., Colicino, E., Oulhote, Y., Di, Q., Kloog, I., Just, A. C., Hou, L., Vokonas, P., Baccarelli, A. A., Weisskopf, M. G. & Schwartz, J. D., Jan 1 2017, In : Environment International. 102, p. 57-65 9 p.

Research output: Contribution to journalArticle

methylation
blood
DNA
ammonium
sulfate
8 Citations (Scopus)

Associations of Accelerometer-Measured and Self-Reported Sedentary Time with Leukocyte Telomere Length in Older Women

Shadyab, A. H., MacEra, C. A., Shaffer, R. A., Jain, S., Gallo, L. C., Lamonte, M. J., Reiner, A. P., Kooperberg, C., Carty, C. L., Di, C., Manini, T. M., Hou, L. & Lacroix, A. Z., Feb 1 2017, In : American journal of epidemiology. 185, 3, p. 172-184 13 p.

Research output: Contribution to journalArticle

Telomere
Leukocytes
Exercise
Linear Models
Women's Health
7 Citations (Scopus)

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Liu, Y., Reynolds, L. M., Ding, J., Hou, L., Lohman, K., Young, T., Cui, W., Huang, Z., Grenier, C., Wan, M., Stunnenberg, H. G., Siscovick, D., Hou, L., Psaty, B. M., Rich, S. S., Rotter, J. I., Kaufman, J. D., Burke, G. L., Murphy, S., Jacobs, D. R. & 8 others, Post, W., Hoeschele, I., Bell, D. A., Herrington, D., Parks, J. S., Tracy, R. P., McCall, C. E. & Stein, J. H., Dec 1 2017, In : Nature communications. 8, 1, 393.

Research output: Contribution to journalArticle

monocytes
arteriosclerosis
Methylation
Gene Expression Profiling
loci
5 Citations (Scopus)

Blood pressure and expression of microRNAs in whole blood

Zhang, Z., Joyce, B. T., Kresovich, J. K., Zheng, Y., Zhong, J., Patel, R., Zhang, W., Liu, L., Dou, C., McCracken, J. P., DõÂaz, A., Motta, V., Sanchez-Guerra, M., Bian, S., Bertazzi, P. A., Schwartz, J., Baccarelli, A. A., Wang, S. & Hou, L., Mar 1 2017, In : PloS one. 12, 3, e0173550.

Research output: Contribution to journalArticle

Blood pressure
MicroRNAs
microRNA
blood pressure
Blood
10 Citations (Scopus)

Changes in the inflammatory potential of diet over time and risk of colorectal cancer in postmenopausal women

Tabung, F. K., Steck, S. E., Ma, Y., Liese, A. D., Zhang, J., Lane, D. S., Ho, G. Y. F., Hou, L., Snetselaar, L., Ockene, J. K. & Hebert, J. R., Sep 1 2017, In : American journal of epidemiology. 186, 5, p. 514-523 10 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Colorectal Neoplasms
Diet
Anti-Inflammatory Agents
Pharmaceutical Preparations
4 Citations (Scopus)

Cord blood DNA methylation and adiposity measures in early and mid-childhood

Kresovich, J. K., Zheng, Y., Cardenas, A., Joyce, B. T., Rifas-Shiman, S. L., Oken, E., Gillman, M. W., Hivert, M. F., Baccarelli, A. A. & Hou, L., Aug 15 2017, In : Clinical Epigenetics. 9, 1, 86.

Research output: Contribution to journalArticle

Adiposity
DNA Methylation
Fetal Blood
Photon Absorptiometry
Pregnancy
16 Citations (Scopus)

Differential DNA methylation and PM2.5 species in a 450K epigenome-wide association study

Dai, L., Mehta, A., Mordukhovich, I., Just, A. C., Shen, J., Hou, L., Koutrakis, P., Sparrow, D., Vokonas, P. S., Baccarelli, A. A. & Schwartz, J. D., Feb 1 2017, In : Epigenetics. 12, 2, p. 139-148 10 p.

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Genes
Computational Biology
Retroviridae Proteins
10 Citations (Scopus)

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

BIOS Consortium, Dec 7 2017, In : American Journal of Human Genetics. 101, 6, p. 888-902 15 p.

Research output: Contribution to journalArticle

DNA Methylation
Blood Pressure
Methylation
Gene Expression
Mendelian Randomization Analysis
86 Citations (Scopus)

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

Quach, A., Levine, M. E., Tanaka, T., Lu, A. T., Chen, B. H., Ferrucci, L., Ritz, B., Bandinelli, S., Neuhouser, M. L., Beasley, J. M., Snetselaar, L., Wallace, R. B., Tsao, P. S., Absher, D., Assimes, T. L., Stewart, J. D., Li, Y., Hou, L., Baccarelli, A. A., Whitsel, E. A. & 1 others, Horvath, S., Jan 1 2017, In : Aging. 9, 2, p. 419-446 28 p.

Research output: Contribution to journalArticle

Epigenomics
Life Style
Diet
Education
Alcohol Drinking
2 Citations (Scopus)

Folate receptor alpha is associated with cervical carcinogenesis and regulates cervical cancer cells growth by activating ERK1/2/c-Fos/c-Jun

Liu, C., Ding, L., Bai, L., Chen, X., Kang, H., Hou, L. & Wang, J., Sep 30 2017, In : Biochemical and Biophysical Research Communications. 491, 4, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

Folate Receptor 1
Cell growth
Uterine Cervical Neoplasms
Carcinogenesis
Proto-Oncogene Proteins c-jun
1 Citation (Scopus)

Formaldehyde alters triglyceride synthesis and very low-density lipoprotein secretion in a time-dependent manner

Bai, J., Wang, P., Liu, Y., Zhang, Y., Li, Y., He, Z., Hou, L. & Liang, R., Dec 1 2017, In : Environmental Toxicology and Pharmacology. 56, p. 15-20 6 p.

Research output: Contribution to journalArticle

VLDL Lipoproteins
Formaldehyde
Triglycerides
Metabolism
AMP-Activated Protein Kinases
2 Citations (Scopus)

Genetic variation in SLC7A2 interacts with calcium and magnesium intakes in modulating the risk of colorectal polyps

Sun, P., Zhu, X., Shrubsole, M. J., Ness, R. M., Hibler, E. A., Cai, Q., Long, J., Chen, Z., Li, G., Hou, L., Smalley, W. E., Edwards, T. L., Giovannucci, E., Zheng, W. & Dai, Q., Sep 1 2017, In : Journal of Nutritional Biochemistry. 47, p. 35-40 6 p.

Research output: Contribution to journalArticle

Polyps
Adenoma
Magnesium
Calcium
Arginine
2 Citations (Scopus)

Gravidity is not associated with telomere length in a biracial cohort of middle-aged women: The Coronary Artery Risk Development in Young Adults (CARDIA) study

Lane-Cordova, A. D., Puterman, E., Gunderson, E. P., Chan, C., Hou, L. & Carnethon, M. R., Oct 1 2017, In : PLoS One. 12, 10, e0186495.

Research output: Contribution to journalArticle

middle-aged adults
Gravidity
telomeres
Telomere
coronary vessels