Linda C Laux

Associate Professor, Pediatrics

Emaill-laux@northwestern.edu

Source: Scopus

Research activity per year

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Personal profile

Research Interests

My clinical and research focus is epilepsy syndromes, genetics of epilepsy syndromes, and Dravet syndrome.

Certifications and Licenses

	Clinical Neurophysiology
	Child Neurology

Training Experience

1993	Residency, University of Arizona Health Science Center
1997	Fellowship, Saint Joseph's Hospital, Phoenix
2001	Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital)

Education/Academic qualification

MD, Saint Louis University

… → 1990

Research interests

EEG
Epigenetics
Epilepsy
Pediatric Neurology

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10 Active
11 Finished

STK-001-DS-101 Monarch Study - An Open-Label Study to Investigate the Safety and Pharmacokinetics of Single Ascending Doses of Antisense Oligonucleotide STK-001 in Children and Adolescents with Dravet Syndrome (IND #140833)
Laux, L. C.
Stoke Therapeutics, Inc.
7/13/20 → 8/31/50
Project: Research project
Stoke STK-001-DS-901: An Observational Study to Investigate Cognition and Quality of Life in Children and Adolescents with Dravet Syndrome (BUTTERFLY)
Laux, L. C.
Stoke Therapeutics, Inc.
12/20/19 → 8/31/50
Project: Research project
ZX008-1900: An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy for Seizures in Patients with Rare Seizure Disorders Such as Epileptic Encephalopathies Including Dravet
Laux, L. C.
Zogenix International Limited
10/31/19 → 8/31/50
Project: Research project
COllaborative Neurology Networks for Enhanced Care through Telehealth for CYE (CONNECT) Consortium
Laux, L. C.
Health Resources and Services Administration, Department of Health and Human Services
9/1/19 → 8/31/23
Project: Research project
TAK -935-001-OLE: A PHASE 2, PROSPECTIVE, INTERVENTIONAL, OPEN-LABEL, MULTI-SITE, EXTENSION STUDY TO ASSESS THE LONG-TERM SAFETY AND TOLERABILITY OF TAK-935 AS ADJUNCTIVE THERAPY IN PATIENTS WITH RARE EPILEPSY
Laux, L. C. & Millichap, J. J.
Ovid Therapeutics Inc.
5/16/19 → 8/31/50
Project: Research project

2206 Citations
28 Article
2 Comment/debate
1 Letter

A single-center, retrospective analysis of genotype-phenotype correlations in children with Dravet syndrome
Gertler, T. S., Calhoun, J. & Laux, L., Feb 2020, In: Seizure. 75, p. 1-6 6 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Corrigendum to “A single-center, retrospective analysis of genotype–phenotype correlations in children with Dravet syndrome” [Seizure: Eur. J. Epilepsy 75 (2020) 1–6] (Seizure: European Journal of Epilepsy (2020) 75 (1–6), (S1059131119304467), (10.1016/j.seizure.2019.12.009))
Gertler, T. S., Calhoun, J. & Laux, L., Aug 2020, In: Seizure. 80, p. 281 1 p.
Research output: Contribution to journal › Comment/debate › peer-review

Open Access
Fenfluramine for Treatment-Resistant Seizures in Patients with Dravet Syndrome Receiving Stiripentol-Inclusive Regimens: A Randomized Clinical Trial
Nabbout, R., Mistry, A., Zuberi, S., Villeneuve, N., Gil-Nagel, A., Sanchez-Carpintero, R., Stephani, U., Laux, L., Wirrell, E., Knupp, K., Chiron, C., Farfel, G., Galer, B. S., Morrison, G., Lock, M., Agarwal, A. & Auvin, S., Mar 2020, In: JAMA Neurology. 77, 3, p. 300-308 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
24 Scopus citations
NCKAP1 Disruptive Variants Lead to a Neurodevelopmental Disorder with Core Features of Autism
Guo, H., Zhang, Q., Dai, R., Yu, B., Hoekzema, K., Tan, J., Tan, S., Jia, X., Chung, W. K., Hernan, R., Alkuraya, F. S., Alsulaiman, A., Al-Muhaizea, M. A., Lesca, G., Pons, L., Labalme, A., Laux, L., Bryant, E., Brown, N. J., Savva, E. & 38 others, Ayres, S., Eratne, D., Peeters, H., Bilan, F., Letienne-Cejudo, L., Gilbert-Dussardier, B., Ruiz-Arana, I. L., Merlini, J. M., Boizot, A., Bartoloni, L., Santoni, F., Karlowicz, D., McDonald, M., Wu, H., Hu, Z., Chen, G., Ou, J., Brasch-Andersen, C., Fagerberg, C. R., Dreyer, I., chun-hui Tsai, A., Slegesky, V., McGee, R. B., Daniels, B., Sellars, E. A., Carpenter, L. A., Schaefer, B., Sacoto, M. J. G., Begtrup, A., Schnur, R. E., Punj, S., Wentzensen, I. M., Rhodes, L., Pan, Q., Bernier, R. A., Chen, C., Eichler, E. E. & Xia, K., Nov 5 2020, In: American journal of human genetics. 107, 5, p. 963-976 14 p.
Research output: Contribution to journal › Article › peer-review
Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial
FAiRE DS Study Group, Dec 21 2019, In: The Lancet. 394, 10216, p. 2243-2254 12 p.
Research output: Contribution to journal › Article › peer-review
37 Scopus citations