Linda C Laux

  • 1321 Citations
20072019
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Research Output 2007 2019

  • 1321 Citations
  • 24 Article
  • 1 Comment/debate
  • 1 Letter
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Article
2019
10 Citations (Scopus)

Long-term cannabidiol treatment in patients with Dravet syndrome: An open-label extension trial

Devinsky, O., Nabbout, R., Miller, I., Laux, L. C., Zolnowska, M., Wright, S. & Roberts, C., Feb 1 2019, In : Epilepsia. 60, 2, p. 294-302 9 p.

Research output: Contribution to journalArticle

Cannabidiol
Myoclonic Epilepsy
Seizures
Therapeutics
Caregivers
4 Citations (Scopus)

Long-term safety and efficacy of cannabidiol in children and adults with treatmentresistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access program results

Laux, L. C., Bebin, E. M., Checketts, D., Chez, M., Flamini, R., Marsh, E. D., Miller, I., Nichol, K., Park, Y., Segal, E., Seltzer, L., Szaflarski, J. P., Thiele, E. A. & Weinstock, A., Aug 1 2019, In : Epilepsy Research. 154, p. 13-20 8 p.

Research output: Contribution to journalArticle

Open Access
Cannabidiol
Myoclonic Epilepsy
Seizures
Safety
Anticonvulsants

Seizure burden in severe early-life epilepsy: Perspectives from parents

Berg, A. T., Kaiser, K., Dixon-Salazar, T., Elliot, A., McNamara, N., Meskis, M. A., Golbeck, E., Tatachar, P., Laux, L., Raia, C., Stanley, J., Luna, A. & Rozek, C., Jun 1 2019, In : Epilepsia Open. 4, 2, p. 293-301 9 p.

Research output: Contribution to journalArticle

Open Access
Epilepsy
Seizures
Parents
Education
Caregivers

The ketogenic diet in children 3 years of age or younger: a 10-year single-center experience

Kim, S. H., Shaw, A., Blackford, R., Lowman, W., Laux, L. C., Millichap, J. J. & Nordli, D. R., Dec 1 2019, In : Scientific reports. 9, 1, 8736.

Research output: Contribution to journalArticle

Open Access
Ketogenic Diet
Seizures
Medical Records
2018
144 Citations (Scopus)

Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial

GWPCARE4 Study Group, Jan 1 2018, In : The Lancet. 391, 10125, p. 1085-1096 12 p.

Research output: Contribution to journalArticle

Cannabidiol
Seizures
Placebos
Therapeutics
Lennox Gastaut Syndrome
36 Citations (Scopus)

Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results

CBD EAP study group, Aug 1 2018, In : Epilepsia. 59, 8, p. 1540-1548 9 p.

Research output: Contribution to journalArticle

Cannabidiol
Epilepsy
Seizures
Safety
Anticonvulsants
23 Citations (Scopus)

Open-label use of highly purified CBD (Epidiolex®) in patients with CDKL5 deficiency disorder and Aicardi, Dup15q, and Doose syndromes

Devinsky, O., Verducci, C., Thiele, E. A., Laux, L. C., Patel, A. D., Filloux, F., Szaflarski, J. P., Wilfong, A., Clark, G. D., Park, Y. D., Seltzer, L. E., Bebin, E. M., Flamini, R., Wechsler, R. T. & Friedman, D., Sep 2018, In : Epilepsy and Behavior. 86, p. 131-137 7 p.

Research output: Contribution to journalArticle

Cannabidiol
Epilepsy
Seizures
Safety
Aicardi Syndrome
15 Citations (Scopus)

Severe peri-ictal respiratory dysfunction is common in Dravet syndrome

Kim, Y., Bravo, E., Thirnbeck, C. K., Smith-Mellecker, L. A., Kim, S. H., Gehlbach, B. K., Laux, L. C., Zhou, X., Nordli, D. R. & Richerson, G. B., Mar 1 2018, In : Journal of Clinical Investigation. 128, 3, p. 1141-1153 13 p.

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Bradycardia
Stroke
Epilepsy
Sudden Death
2017
45 Citations (Scopus)

Cannabidiol as a Potential Treatment for Febrile Infection-Related Epilepsy Syndrome (FIRES) in the Acute and Chronic Phases

Gofshteyn, J. S., Wilfong, A., Devinsky, O., Bluvstein, J., Charuta, J., Ciliberto, M. A., Laux, L. C. & Marsh, E. D., Jan 1 2017, In : Journal of child neurology. 32, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

Cannabidiol
Epilepsy
Fever
Infection
Anticonvulsants
41 Citations (Scopus)

Optimizing the Diagnosis and Management of Dravet Syndrome: Recommendations From a North American Consensus Panel

Wirrell, E. C., Laux, L., Donner, E., Jette, N., Knupp, K., Meskis, M. A., Miller, I., Sullivan, J., Welborn, M. & Berg, A. T., Mar 1 2017, In : Pediatric Neurology. 68, p. 18-34.e3

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Consensus
Seizures
Comorbidity
Genetic Testing
Myoclonic Epilepsy
Genetic Models
Anticonvulsants
Epilepsy
Seizures
4 Citations (Scopus)

Seizure Outcomes in Children Following Electrocorticography-Guided Single-Stage Surgical Resection

Bansal, S., Kim, A. J., Berg, A. T., Koh, S., Laux, L. C., Nangia, S., Millichap, J. J., Shaw, A., Fisher, B., Dezort, C., DiPatri, A. J., Alden, T. D. & Nordli, D. R., Jun 1 2017, In : Pediatric Neurology. 71, p. 35-42 8 p.

Research output: Contribution to journalArticle

Seizures
Epilepsy
Length of Stay
Implanted Electrodes
Neoplasms
297 Citations (Scopus)

Trial of cannabidiol for drug-resistant seizures in the dravet syndrome

Devinsky, O., Cross, J. H., Laux, L., Marsh, E., Miller, I., Nabbout, R., Scheffer, I. E., Thiele, E. A. & Wright, S., May 25 2017, In : New England Journal of Medicine. 376, 21, p. 2011-2020 10 p.

Research output: Contribution to journalArticle

Cannabidiol
Myoclonic Epilepsy
Seizures
Placebos
Pharmaceutical Preparations
2016
297 Citations (Scopus)

Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial

Devinsky, O., Marsh, E., Friedman, D., Thiele, E., Laux, L. C., Sullivan, J., Miller, I., Flamini, R., Wilfong, A., Filloux, F., Wong, M., Tilton, N., Bruno, P., Bluvstein, J., Hedlund, J., Kamens, R., Maclean, J., Nangia, S., Singhal, N. S., Wilson, C. A. & 2 others, Patel, A. & Cilio, M. R., Jan 1 2016, In : The Lancet Neurology. 15, 3, p. 270-278 9 p.

Research output: Contribution to journalArticle

Cannabidiol
Epilepsy
Seizures
Therapeutics
Safety
2015
10 Citations (Scopus)

Ictal ontogeny in Dravet syndrome

Kim, S. H., Nordli, D. R., Berg, A. T., Koh, S. & Laux, L. C., Mar 1 2015, In : Clinical Neurophysiology. 126, 3, p. 446-455 10 p.

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Seizures
Stroke
Age Groups
Video Recording
2013
47 Citations (Scopus)

Stiripentol in Dravet syndrome: Results of a retrospective U.S. study

Wirrell, E. C., Laux, L. C., Franz, D. N., Sullivan, J., Saneto, R. P., Morse, R. P., Devinsky, O., Chugani, H., Hernandez, A., Hamiwka, L., Mikati, M. A., Valencia, I., Le Guern, M. E., Chancharme, L. & De Menezes, M. S., Sep 1 2013, In : Epilepsia. 54, 9, p. 1595-1604 10 p.

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Retrospective Studies
Seizures
Valproic Acid
stiripentol
28 Citations (Scopus)

The ketogenic diet in dravet syndrome

Laux, L. C. & Blackford, R., Aug 1 2013, In : Journal of Child Neurology. 28, 8, p. 1041-1044 4 p.

Research output: Contribution to journalArticle

Ketogenic Diet
Myoclonic Epilepsy
Seizures
Gait Ataxia
Comorbidity
2011
20 Citations (Scopus)

Alleged cases of vaccine encephalopathy rediagnosed years later as dravet syndrome

Reyes, I. S., Hsieh, D. T., Laux, L. C. & Wilfong, A. A., Sep 1 2011, In : Pediatrics. 128, 3

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Brain Diseases
Vaccines
Mutation
Sodium Channels
18 Citations (Scopus)

Ictal asystole and anti-N-methyl-D-aspartate receptor antibody encephalitis

Millichap, J. J., Goldstein, J. L., Laux, L. C., Nordli, D. R., Stack, C. V. & Wainwright, M., Mar 1 2011, In : Pediatrics. 127, 3

Research output: Contribution to journalArticle

Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Heart Arrest
Seizures
Stroke
Antibodies
2009
133 Citations (Scopus)

Cellular injury and neuroinflammation in children with chronic intractable epilepsy

Choi, J., Nordli, D. R., Alden, T. D., DiPatri, A. J., Laux, L. C., Kelley, K., Rosenow, J. M., Schuele, S. U., Rajaram, V. & Koh, S., Dec 19 2009, In : Journal of Neuroinflammation. 6, 38.

Research output: Contribution to journalArticle

Astrocytes
Microglia
Epilepsy
Wounds and Injuries
Cell Death
20 Citations (Scopus)

Child neurology: Dravet syndrome: When to suspect the diagnosis

Millichap, J. J., Koh, S., Laux, L. C. & Nordli, D. R., Jan 1 2009, In : Neurology. 73, 13

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Neurology
Seizures
Febrile Seizures
Status Epilepticus
2008
1 Citation (Scopus)
Hospital Emergency Service
Seizures
Pediatrics
Medical Assistance
Status Epilepticus
53 Citations (Scopus)

When do seizures usually improve with the ketogenic diet?

Kossoff, E. H., Laux, L. C., Blackford, R., Morrison, P. F., Pyzik, P. L., Hamdy, R. M., Turner, Z. & Nordli, D. R., Feb 1 2008, In : Epilepsia. 49, 2, p. 329-333 5 p.

Research output: Contribution to journalArticle

Ketogenic Diet
Seizures
Fasting
Baltimore
Parents
2007
58 Citations (Scopus)

Dravet syndrome (severe myoclonic epilepsy in infancy): A retrospective study of 16 patients

Korff, C., Laux, L. C., Kelley, K., Goldstein, J. L., Koh, S. & Nordli, D., Feb 1 2007, In : Journal of child neurology. 22, 2, p. 185-194 10 p.

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Retrospective Studies
Ketogenic Diet
Mutation
Valproic Acid