Linda C Laux

  • 1735 Citations
20072020

Research output per year

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Research Output

  • 1735 Citations
  • 27 Article
  • 1 Comment/debate
  • 1 Letter
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Article
2020

A single-center, retrospective analysis of genotype-phenotype correlations in children with Dravet syndrome

Gertler, T. S., Calhoun, J. & Laux, L., Feb 2020, In : Seizure. 75, p. 1-6 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Fenfluramine for Treatment-Resistant Seizures in Patients with Dravet Syndrome Receiving Stiripentol-Inclusive Regimens: A Randomized Clinical Trial

Nabbout, R., Mistry, A., Zuberi, S., Villeneuve, N., Gil-Nagel, A., Sanchez-Carpintero, R., Stephani, U., Laux, L., Wirrell, E., Knupp, K., Chiron, C., Farfel, G., Galer, B. S., Morrison, G., Lock, M., Agarwal, A. & Auvin, S., Mar 2020, In : JAMA Neurology. 77, 3, p. 300-308 9 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
2019

Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial

FAiRE DS Study Group, Dec 21 2019, In : The Lancet. 394, 10216, p. 2243-2254 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Long-term cannabidiol treatment in patients with Dravet syndrome: An open-label extension trial

Devinsky, O., Nabbout, R., Miller, I., Laux, L. C., Zolnowska, M., Wright, S. & Roberts, C., Feb 1 2019, In : Epilepsia. 60, 2, p. 294-302 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Long-term safety and efficacy of cannabidiol in children and adults with treatmentresistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access program results

Laux, L. C., Bebin, E. M., Checketts, D., Chez, M., Flamini, R., Marsh, E. D., Miller, I., Nichol, K., Park, Y., Segal, E., Seltzer, L., Szaflarski, J. P., Thiele, E. A. & Weinstock, A., Aug 2019, In : Epilepsy Research. 154, p. 13-20 8 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Seizure burden in severe early-life epilepsy: Perspectives from parents

Berg, A. T., Kaiser, K., Dixon-Salazar, T., Elliot, A., McNamara, N., Meskis, M. A., Golbeck, E., Tatachar, P., Laux, L., Raia, C., Stanley, J., Luna, A. & Rozek, C., Jun 2019, In : Epilepsia Open. 4, 2, p. 293-301 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The ketogenic diet in children 3 years of age or younger: a 10-year single-center experience

Kim, S. H., Shaw, A., Blackford, R., Lowman, W., Laux, L. C., Millichap, J. J. & Nordli, D., Dec 1 2019, In : Scientific reports. 9, 1, 8736.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial

GWPCARE4 Study Group, Jan 1 2018, In : The Lancet. 391, 10125, p. 1085-1096 12 p.

Research output: Contribution to journalArticle

219 Scopus citations

Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results

CBD EAP study group, Aug 2018, In : Epilepsia. 59, 8, p. 1540-1548 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Open-label use of highly purified CBD (Epidiolex®) in patients with CDKL5 deficiency disorder and Aicardi, Dup15q, and Doose syndromes

Devinsky, O., Verducci, C., Thiele, E. A., Laux, L. C., Patel, A. D., Filloux, F., Szaflarski, J. P., Wilfong, A., Clark, G. D., Park, Y. D., Seltzer, L. E., Bebin, E. M., Flamini, R., Wechsler, R. T. & Friedman, D., Sep 2018, In : Epilepsy and Behavior. 86, p. 131-137 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Severe peri-ictal respiratory dysfunction is common in Dravet syndrome

Kim, Y., Bravo, E., Thirnbeck, C. K., Smith-Mellecker, L. A., Kim, S. H., Gehlbach, B. K., Laux, L. C., Zhou, X., Nordli, D. & Richerson, G. B., Mar 1 2018, In : Journal of Clinical Investigation. 128, 3, p. 1141-1153 13 p.

Research output: Contribution to journalArticle

26 Scopus citations
2017

Cannabidiol as a Potential Treatment for Febrile Infection-Related Epilepsy Syndrome (FIRES) in the Acute and Chronic Phases

Gofshteyn, J. S., Wilfong, A., Devinsky, O., Bluvstein, J., Charuta, J., Ciliberto, M. A., Laux, L. & Marsh, E. D., Jan 1 2017, In : Journal of child neurology. 32, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Optimizing the Diagnosis and Management of Dravet Syndrome: Recommendations From a North American Consensus Panel

Wirrell, E. C., Laux, L., Donner, E., Jette, N., Knupp, K., Meskis, M. A., Miller, I., Sullivan, J., Welborn, M. & Berg, A. T., Mar 1 2017, In : Pediatric neurology. 68, p. 18-34.e3

Research output: Contribution to journalArticle

56 Scopus citations

Seizure Outcomes in Children Following Electrocorticography-Guided Single-Stage Surgical Resection

Bansal, S., Kim, A. J., Berg, A. T., Koh, S., Laux, L. C., Nangia, S., Millichap, J. J., Shaw, A., Fisher, B., Dezort, C., DiPatri, A. J., Alden, T. D. & Nordli, D., Jun 2017, In : Pediatric neurology. 71, p. 35-42 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Trial of cannabidiol for drug-resistant seizures in the dravet syndrome

Devinsky, O., Cross, J. H., Laux, L., Marsh, E., Miller, I., Nabbout, R., Scheffer, I. E., Thiele, E. A. & Wright, S., May 25 2017, In : New England Journal of Medicine. 376, 21, p. 2011-2020 10 p.

Research output: Contribution to journalArticle

408 Scopus citations
2016

Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial

Devinsky, O., Marsh, E., Friedman, D., Thiele, E., Laux, L., Sullivan, J., Miller, I., Flamini, R., Wilfong, A., Filloux, F., Wong, M., Tilton, N., Bruno, P., Bluvstein, J., Hedlund, J., Kamens, R., Maclean, J., Nangia, S., Singhal, N. S., Wilson, C. A. & 2 others, Patel, A. & Cilio, M. R., Jan 1 2016, In : The Lancet Neurology. 15, 3, p. 270-278 9 p.

Research output: Contribution to journalArticle

367 Scopus citations
2015

Ictal ontogeny in Dravet syndrome

Kim, S. H., Nordli, D., Berg, A. T., Koh, S. & Laux, L., Mar 1 2015, In : Clinical Neurophysiology. 126, 3, p. 446-455 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2013

Stiripentol in Dravet syndrome: Results of a retrospective U.S. study

Wirrell, E. C., Laux, L. C., Franz, D. N., Sullivan, J., Saneto, R. P., Morse, R. P., Devinsky, O., Chugani, H., Hernandez, A., Hamiwka, L., Mikati, M. A., Valencia, I., Le Guern, M. E., Chancharme, L. & De Menezes, M. S., Sep 1 2013, In : Epilepsia. 54, 9, p. 1595-1604 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

The ketogenic diet in dravet syndrome

Laux, L. & Blackford, R., Aug 1 2013, In : Journal of child neurology. 28, 8, p. 1041-1044 4 p.

Research output: Contribution to journalArticle

32 Scopus citations
2011

Alleged cases of vaccine encephalopathy rediagnosed years later as dravet syndrome

Reyes, I. S., Hsieh, D. T., Laux, L. C. & Wilfong, A. A., Sep 1 2011, In : Pediatrics. 128, 3

Research output: Contribution to journalArticle

22 Scopus citations

Ictal asystole and anti-N-methyl-D-aspartate receptor antibody encephalitis

Millichap, J. J., Goldstein, J. L., Laux, L. C., Nordli, D., Stack, C. V. & Wainwright, M., Mar 1 2011, In : Pediatrics. 127, 3

Research output: Contribution to journalArticle

18 Scopus citations
2009

Cellular injury and neuroinflammation in children with chronic intractable epilepsy

Choi, J., Nordli, D., Alden, T. D., DiPatri, A., Laux, L., Kelley, K., Rosenow, J., Schuele, S. U., Rajaram, V. & Koh, S., Dec 19 2009, In : Journal of Neuroinflammation. 6, 38.

Research output: Contribution to journalArticle

139 Scopus citations

Child neurology: Dravet syndrome: When to suspect the diagnosis

Millichap, J. J., Koh, S., Laux, L. C. & Nordli, D., Sep 2009, In : Neurology. 73, 13, p. e59-e62

Research output: Contribution to journalArticle

21 Scopus citations
2008
2 Scopus citations

When do seizures usually improve with the ketogenic diet?

Kossoff, E. H., Laux, L. C., Blackford, R., Morrison, P. F., Pyzik, P. L., Hamdy, R. M., Turner, Z. & Nordli, D., Feb 1 2008, In : Epilepsia. 49, 2, p. 329-333 5 p.

Research output: Contribution to journalArticle

56 Scopus citations
2007

Dravet syndrome (severe myoclonic epilepsy in infancy): A retrospective study of 16 patients

Korff, C., Laux, L., Kelley, K., Goldstein, J., Koh, S. & Nordli, D., Feb 1 2007, In : Journal of child neurology. 22, 2, p. 185-194 10 p.

Research output: Contribution to journalArticle

59 Scopus citations