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Lisa D Wilsbacher

  • 4460 Citations
19972019

Research output per year

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Personal profile

Research Interests

Dr. Wilsbacher's research focuses on cardiac development and cardiomyocyte maintenance in the setting of pathological stress. Currently, the laboratory investigates the G protein-coupled receptor sphingosine-1-phosphate receptor 1 (S1Pr1) and its unexpected role in cardiomyocyte proliferation and cardiac development. Her research aims to identify the signaling mechanisms that underlie these cardiac developmental effects and to investigate whether S1Pr1 signaling contributes to cardiac remodeling in the adult heart.

Training Experience

2004Internship, University of California- San Francisco Medical Center
2007Residency, University of California- San Francisco Medical Center
2009Fellowship, University of California- San Francisco Medical Center

Education/Academic qualification

MD, Northwestern University Feinberg School of Medicine

… → 2003

PhD, Northwestern University

… → 2001

Research interests

  • Cardiomyopathy
  • Developmental Biology
  • Fibrosis
  • Gene Regulation
  • Genomic Medicine/Personalized Medicine
  • Molecular Biology
  • Phospholipids
  • TGF-beta

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Grants

Gilead Sciences Research Scholars program

Wilsbacher, L. D.

Gilead Sciences, Inc.

6/22/15 → 6/21/17

Project: Research project

Exploring the roles of Gi and S1Pr1 in endothelial barrier function in vivo

Wilsbacher, L. D.

National Heart, Lung, and Blood Institute

3/2/15 → 2/29/16

Project: Research project

    • Research Output

    • 4460 Citations
    • 19 Article
    • 1 Comment/debate
    • 1 Review article

    Macrophages in Heart Failure with Reduced versus Preserved Ejection Fraction

    DeBerge, M., Shah, S. J., Wilsbacher, L. & Thorp, E. B., Apr 2019, In : Trends in Molecular Medicine. 25, 4, p. 328-340 13 p.

    Research output: Contribution to journal › Review article

    • 1 Scopus citations

    Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation

    Liu, P., Wysocki, J., Souma, T., Ye, M., Ramirez, V., Zhou, B., Wilsbacher, L. D., Quaggin, S. E., Batlle, D. & Jin, J., Jul 1 2018, In : Kidney international. 94, 1, p. 114-125 12 p.

    Research output: Contribution to journal › Article

    • 6 Scopus citations

    A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis

    Rai, R., Verma, S. K., Kim, D., Ramirez, V., Lux, E., Li, C., Sahoo, S., Wilsbacher, L. D., Vaughan, D. E., Quaggin, S. E. & Ghosh, A. K., Nov 2 2017, In : Epigenetics. 12, 11, p. 1004-1013 10 p.

    Research output: Contribution to journal › Article

    • 6 Scopus citations

    Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy

    Barefield, D. Y., Puckelwartz, M. J., Kim, E. Y., Wilsbacher, L. D., Vo, A. H., Waters, E. A., Earley, J. U., Hadhazy, M., Dellefave-Castillo, L., Pesce, L. L. & McNally, E. M., Oct 17 2017, In : Circulation. 136, 16, p. 1477-1491 15 p.

    Research output: Contribution to journal › Article

    • 13 Scopus citations

    Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2

    Yang, X., Park, S. H., Chang, H. C., Shapiro, J. S., Vassilopoulos, A., Sawicki, K. T., Chen, C., Shang, M., Burridge, P. W., Epting, C. L., Wilsbacher, L. D., Jenkitkasemwong, S., Knutson, M., Gius, D. & Ardehali, H., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1505-1516 12 p.

    Research output: Contribution to journal › Article

    • 29 Scopus citations