Lisa D Wilsbacher

  • 4387 Citations
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Personal profile

Research Interests

Dr. Wilsbacher's research focuses on cardiac development and cardiomyocyte maintenance in the setting of pathological stress. Currently, the laboratory investigates the G protein-coupled receptor sphingosine-1-phosphate receptor 1 (S1Pr1) and its unexpected role in cardiomyocyte proliferation and cardiac development. Her research aims to identify the signaling mechanisms that underlie these cardiac developmental effects and to investigate whether S1Pr1 signaling contributes to cardiac remodeling in the adult heart.

Training Experience

2004Internship, University of California- San Francisco Medical Center
2007Residency, University of California- San Francisco Medical Center
2009Fellowship, University of California- San Francisco Medical Center

Education/Academic qualification

MD, Northwestern University Feinberg School of Medicine

… → 2003

PhD, Northwestern University

… → 2001

Research interests

  • Cardiomyopathy
  • Developmental Biology
  • Fibrosis
  • Gene Regulation
  • Genomic Medicine/Personalized Medicine
  • Molecular Biology
  • Phospholipids
  • TGF-beta

Fingerprint Dive into the research topics where Lisa D Wilsbacher is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Cardiac Myocytes Medicine & Life Sciences
Circadian Clocks Medicine & Life Sciences
Lysosphingolipid Receptors Medicine & Life Sciences
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Genes Medicine & Life Sciences
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Circadian Rhythm Medicine & Life Sciences
Clocks Chemical Compounds

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Grants 2015 2017

Lysosphingolipid Receptors
Blood Vessels
Research Personnel

Research Output 1997 2019

  • 4387 Citations
  • 19 Article
  • 1 Comment/debate
  • 1 Review article
1 Citation (Scopus)

Macrophages in Heart Failure with Reduced versus Preserved Ejection Fraction

DeBerge, M., Shah, S. J., Wilsbacher, L. D. & Thorp, E. B., Apr 1 2019, In : Trends in Molecular Medicine. 25, 4, p. 328-340 13 p.

Research output: Contribution to journalReview article

Heart Failure
5 Citations (Scopus)
Renin-Angiotensin System
Angiotensin II
Blood Pressure
Transgenic Mice
5 Citations (Scopus)

A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis

Rai, R., Verma, S. K., Kim, D., Ramirez, V., Lux, E., Li, C., Sahoo, S., Wilsbacher, L. D., Vaughan, D. E., Quaggin, S. E. & Ghosh, A. K., Nov 2 2017, In : Epigenetics. 12, 11, p. 1004-1013 10 p.

Research output: Contribution to journalArticle

Mesangial Cells
10 Citations (Scopus)

Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy

Barefield, D. Y., Puckelwartz, M. J., Kim, E. Y., Wilsbacher, L. D., Vo, A. H., Waters, E. A., Earley, J. U., Hadhazy, M., Dellefave-Castillo, L., Pesce, L. L. & McNally, E. M., Oct 17 2017, In : Circulation. 136, 16, p. 1477-1491 15 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Cardiac Arrhythmias
Carrier Proteins
27 Citations (Scopus)

Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2

Yang, X., Park, S. H., Chang, H. C., Shapiro, J. S., Vassilopoulos, A., Sawicki, K. T., Chen, C., Shang, M., Burridge, P. W., Epting, C. L., Wilsbacher, L. D., Jenkitkasemwong, S., Knutson, M., Gius, D. & Ardehali, H., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1505-1516 12 p.

Research output: Contribution to journalArticle

Sirtuin 2
Transcription Factors