Grants per year
Personal profile
Research Interests
Dr. Wilsbacher's research focuses on cardiac development and cardiomyocyte maintenance in the setting of pathological stress. Currently, the laboratory investigates the G protein-coupled receptor sphingosine-1-phosphate receptor 1 (S1Pr1) and its unexpected role in cardiomyocyte proliferation and cardiac development. Her research aims to identify the signaling mechanisms that underlie these cardiac developmental effects and to investigate whether S1Pr1 signaling contributes to cardiac remodeling in the adult heart.
Training Experience
| 2004 | Internship, University of California- San Francisco Medical Center |
| 2007 | Residency, University of California- San Francisco Medical Center |
| 2009 | Fellowship, University of California- San Francisco Medical Center |
Education/Academic qualification
Medicine, MD, Northwestern University
… → 2003
PhD, Neuroscience, Northwestern University
… → 2001
Research interests keywords
- Cardiomyopathy
- Developmental Biology
- Fibrosis
- Gene Regulation
- Genomic Medicine/Personalized Medicine
- Molecular Biology
- Phospholipids
- TGF-beta
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Pleiotropic Role of PAI-1 in Cardiovascular Aging
Vaughan, D. E., Abdala-Valencia, H., Burridge, P., Wilsbacher, L. D. & Zhang, W.
National Heart, Lung, and Blood Institute
8/1/23 → 5/31/28
Project: Research project
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Exploring the roles of Gi and S1Pr1 in endothelial barrier function in vivo
National Heart, Lung, and Blood Institute
3/2/15 → 2/29/16
Project: Research project
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Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload
Ghosh, A. K., Kalousdian, A. A., Shang, M., Lux, E., Eren, M., Keating, A., Wilsbacher, L. D. & Vaughan, D. E., Nov 27 2022, (E-pub ahead of print) In: Cellular Signalling. p. 110555Research output: Contribution to journal › Article › peer-review
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Combined modality PET/MR for the detection of severe large vessel vasculitis
Cerne, J. W., Liu, S., Umair, M., Pathrose, A., Moore, J. E., Allen, B. D., Markl, M., Carr, J. C., Savas, H., Wilsbacher, L. & Avery, R., Dec 2022, In: European Journal of Hybrid Imaging. 6, 1, 16.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Ischemic dual papillary muscle rupture in a postpartum patient with vascular Ehlers-Danlos syndrome
Erfe, J. M., Devlin, P., Rich, J., Wilsbacher, L., Schimmel, D., McCarthy, P. & Pawale, A., Oct 2022, In: JTCVS Techniques. 15, p. 84-86 3 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Valve-sparing versus valve-replacing aortic root replacement in patients with aortic root aneurysm
Malaisrie, S. C., Kislitsina, O. N., Wilsbacher, L., Mendelson, M., Puthumana, J. J., Vassallo, P., Kruse, J., Andrei, A. C. & McCarthy, P. M., Jul 2022, In: Journal of Cardiac Surgery. 37, 7, p. 1947-1956 10 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
COL3A1 Missense Variant in a Patient Presenting With Hemoptysis
Riaz, A., Portocarrero, J. P., Hoel, A., Yeldandi, A., Dellefave-Castillo, L., Paparello, J., D′amico, J. D. M. & Wilsbacher, L. D., Oct 1 2021, In: Circulation: Genomic and Precision Medicine. 14, 5, p. E003386Research output: Contribution to journal › Letter › peer-review
Open Access