Lisa D Wilsbacher

  • 4307 Citations
19972019
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Research Output 1997 2019

  • 4307 Citations
  • 18 Article
  • 2 Review article
  • 1 Comment/debate
2019

Macrophages in Heart Failure with Reduced versus Preserved Ejection Fraction

DeBerge, M., Shah, S. J., Wilsbacher, L. D. & Thorp, E. B., Apr 1 2019, In : Trends in Molecular Medicine. 25, 4, p. 328-340 13 p.

Research output: Contribution to journalReview article

Heart Failure
Macrophages
Biomarkers
Inflammation
Incidence
2018
4 Citations (Scopus)
Renin-Angiotensin System
Angiotensin II
Hypertension
Blood Pressure
Transgenic Mice
2017
5 Citations (Scopus)

A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis

Rai, R., Verma, S. K., Kim, D., Ramirez, V., Lux, E., Li, C., Sahoo, S., Wilsbacher, L. D., Vaughan, D. E., Quaggin, S. E. & Ghosh, A. K., Nov 2 2017, In : Epigenetics. 12, 11, p. 1004-1013 10 p.

Research output: Contribution to journalArticle

Fibrosis
Hypertension
Kidney
Podocytes
Mesangial Cells
9 Citations (Scopus)

Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy

Barefield, D. Y., Roy-Puckelwartz, M. J., Kim, E. Y., Wilsbacher, L. D., Vo, A. H., Waters, E. A., Earley, J. U., Hadhazy, M., Castillo, L. M., Pesce, L. L. & McNally, E. M., Oct 17 2017, In : Circulation. 136, 16, p. 1477-1491 15 p.

Research output: Contribution to journalArticle

Myofibrils
Dilated Cardiomyopathy
Myosins
Cardiac Arrhythmias
Carrier Proteins
26 Citations (Scopus)

Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2

Yang, X., Park, S. H., Chang, H. C., Shapiro, J. S., Vasilopoulos, A., Sawicki, K. T., Chen, C., Shang, M., Burridge, P., Epting, C. L., Wilsbacher, L. D., Jenkitkasemwong, S., Knutson, M., Gius, D. R. & Ardehali, H., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1505-1516 12 p.

Research output: Contribution to journalArticle

Sirtuin 2
Homeostasis
Transcription Factors
Iron
Lysine
2016
19 Citations (Scopus)

A small molecule inhibitor of PAI-1 protects against Doxorubicin-induced cellular senescence: molecular basis

Ghosh, A. K., Rai, R., Park, K. E., Eren, M., Miyata, T., Wilsbacher, L. D. & Vaughan, D. E., Oct 6 2016, In : Oncotarget. 7, 45, p. 72443-72457 15 p.

Research output: Contribution to journalArticle

Cell Aging
Plasminogen Activator Inhibitor 1
Doxorubicin
Fibroblasts
Serine Proteinase Inhibitors
6 Citations (Scopus)
heart failure
Cardiac Myocytes
Heart Failure
Growth
cardiomyopathy
15 Citations (Scopus)

Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development

Clay, H., Wilsbacher, L. D., Wilson, S. J., Duong, D. N., McDonald, M., Lam, I., Park, K. E., Chun, J. & Coughlin, S. R., Oct 1 2016, In : Developmental Biology. 418, 1, p. 157-165 9 p.

Research output: Contribution to journalArticle

Lysosphingolipid Receptors
Coitus
Cardiac Myocytes
Galactosidases
Staining and Labeling
2015
5 Citations (Scopus)

Analysis of cardiomyocyte development using immunofluorescence in embryonic mouse heart

Wilsbacher, L. D. & Coughlin, S. R., Mar 26 2015, In : Journal of Visualized Experiments. 97

Research output: Contribution to journalArticle

Cardiac Myocytes
Fluorescent Antibody Technique
Myofibrils
Costameres
Sarcomeres
3 Citations (Scopus)

Angiotensins and the Heart: Is Angiotensin-(1-7) Cardioprotective?

Wysocki, J., Wilsbacher, L. D. & Batlle, D., Aug 20 2015, In : Hypertension. 66, 2, p. 260-262 3 p.

Research output: Contribution to journalComment/debate

Diastolic Heart Failure
Desoxycorticosterone Acetate
Angiotensin I
Peptide Fragments
Angiotensins
35 Citations (Scopus)

An internal promoter underlies the difference in disease severity between N-and C-terminal truncation mutations of titin in zebrafish

Zou, J., Tran, D., Baalbaki, M., Tang, L. F., Poon, A., Pelonero, A., Titus, E. W., Yuan, C., Shi, C., Patchava, S., Halper, E., Garg, J., Movsesyan, I., Yin, C., Wu, R., Wilsbacher, L. D., Liu, J., Hager, R. L., Coughlin, S. R., Jinek, M. & 5 others, Pullinger, C. R., Kane, J. P., Hart, D. O., Kwok, P. Y. & Deo, R. C., Oct 16 2015, In : eLife. 4, OCTOBER2015, e09406.

Research output: Contribution to journalArticle

Connectin
Zebrafish
Mutation
Clustered Regularly Interspaced Short Palindromic Repeats
Dilated Cardiomyopathy
2010
34 Citations (Scopus)

Roles and interactions among protease-activated receptors and P2ry12 in hemostasis and thrombosis

Cornelissen, I., Palmer, D., David, T., Wilsbacher, L., Concengco, C., Conley, P., Pandey, A. & Coughlin, S. R., Oct 26 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 43, p. 18605-18610 6 p.

Research output: Contribution to journalArticle

Proteinase-Activated Receptors
Hemostasis
Thrombin
Thrombosis
Blood Platelets
2006
174 Citations (Scopus)

Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice

McDearmon, E. L., Patel, K. N., Ko, C. H., Walisser, J. A., Schook, A. C., Chong, J. L., Wilsbacher, L. D., Song, E. J., Hong, H., Bradfield, C. A. & Takahashi, J. S., Nov 24 2006, In : Science. 314, 5803, p. 1304-1308 5 p.

Research output: Contribution to journalArticle

ARNTL Transcription Factors
Body Weight
Muscles
Brain
Periodicity
2002
113 Citations (Scopus)

Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice in vivo

Wilsbacher, L. D., Yamazaki, S., Herzog, E. D., Song, E. J., Radcliffe, L. A., Abe, M., Block, G., Spitznagel, E., Menaker, M. & Takahashi, J. S., Jan 8 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 1, p. 489-494 6 p.

Research output: Contribution to journalArticle

Luciferases
Transgenic Mice
Suprachiasmatic Nucleus
Messenger RNA
Light
2000
907 Citations (Scopus)

Mop3 is an essential component of the master circadian pacemaker in mammals

Bunger, M. K., Wilsbacher, L. D., Moran, S. M., Clendenin, C., Radcliffe, L. A., Hogenesch, J. B., Simon, M. C., Takahashi, J. S. & Bradfield, C. A., Dec 22 2000, In : Cell. 103, 7, p. 1009-1017 9 p.

Research output: Contribution to journalArticle

Pacemakers
Mammals
Biological Clocks
Suprachiasmatic Nucleus
Darkness
15 Citations (Scopus)

The mouse Clock locus: Sequence and comparative analysis of 204 kb from mouse chromosome 5

Wilsbacher, L. D., Sangoram, A. M., Antoch, M. P. & Takahashi, J. S., Dec 1 2000, In : Genome Research. 10, 12, p. 1928-1940 13 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 5
Sequence Analysis
Bacterial Artificial Chromosomes
Genes
Basic Helix-Loop-Helix Transcription Factors
1998
67 Citations (Scopus)

Circadian rhythms: Molecular basis of the clock

Wilsbacher, L. D. & Takahashi, J. S., Jan 1 1998, In : Current Opinion in Genetics and Development. 8, 5, p. 595-602 8 p.

Research output: Contribution to journalReview article

Circadian Rhythm
Drosophila
Circadian Clocks
Cyanobacteria
Genes
1295 Citations (Scopus)

Role of the CLOCK protein in the mammalian circadian mechanism

Gekakis, N., Staknis, D., Nguyen, H. B., Davis, F. C., Wilsbacher, L. D., King, D. P., Takahashi, J. S. & Weitz, C. J., Jun 5 1998, In : Science. 280, 5369, p. 1564-1569 6 p.

Research output: Contribution to journalArticle

CLOCK Proteins
Transcription Factors
E-Box Elements
Basic Helix-Loop-Helix Transcription Factors
Circadian Clocks
1997
45 Citations (Scopus)

Adrenocorticotropin induction of stress-activated protein kinase in the adrenal cortex in vivo

Watanabe, G., Pena, P., Albanese, C., Wilsbacher, L. D., Young, J. B. & Pestell, R. G., Aug 8 1997, In : Journal of Biological Chemistry. 272, 32, p. 20063-20069 7 p.

Research output: Contribution to journalArticle

Adrenal Cortex
Heat-Shock Proteins
Adrenocorticotropic Hormone
Protein Kinases
Extracellular Signal-Regulated MAP Kinases
513 Citations (Scopus)

Functional identification of the mouse circadian Clock gene by transgenic BAC rescue

Antoch, M. P., Song, E. J., Chang, A. M., Vitaterna, M. H., Zhao, Y., Wilsbacher, L. D., Sangoram, A. M., King, D. P., Pinto, L. H. & Takahashi, J. S., May 16 1997, In : Cell. 89, 4, p. 655-667 13 p.

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
Circadian Clocks
Chromosomes
Transgenes
Clocks
1017 Citations (Scopus)

Positional cloning of the mouse circadian Clock gene

King, D. P., Zhao, Y., Sangoram, A. M., Wilsbacher, L. D., Tanaka, M., Antoch, M. P., Steeves, T. D. L., Vitaterna, M. H., Kornhauser, J. M., Lowrey, P. L., Turek, F. W. & Takahashi, J. S., May 16 1997, In : Cell. 89, 4, p. 641-653 13 p.

Research output: Contribution to journalArticle

Circadian Clocks
Cloning
CLOCK Proteins
Organism Cloning
Clocks