Grants per year
Personal profile
Research Interests
Starting as a public health and researcher and HIV clinician in the 1980’s, my research has focused on understanding the causes and developing feasible and effective solutions to the implementation gap and disparities in delivery, outcomes and quality of care in resource limited settings in the US and in Africa. This work started during the 15 years I ran the HIV Medical Care Program at Dimock Community Health Center’s HIV Program working to ensure high quality of prevention and care delivered in the community and integrating implementation and improvement science to improve and learn from this work. Relevant recent work has included applying implementation and improvement science methods to identify factors associated with poorer quality, low rates of health system responsiveness and patient-centered care, inequity and outcomes in care in the US and in Africa and the Caribbean, identifying, adapting and testing existing evidence-based interventions to address these gaps. As Director for Implementation and Improvement Sciences at Ariadne Labs, a partnership between Harvard School and Public Health and Brigham and Women’s Hospital, I led a team focused on developing more effective approaches to study and support innovative approaches to apply evidence-based practices from initial discovery of simple effective solutions through scale-up to realize the full potential to improve care and reduce suffering and improve patient-centered outcomes and care delivery. At Northwestern Feinberg School of Medicine as Professor in the Departments of Medical Social Sciences and Psychiatry, member of the Third Coast Center for AIDS Research, my current work continues to focus on continuing the work to further apply implementation science methods to effectively measure and improve implementation and quality and effectiveness of care in the US and a number of countries in Africa. Throughout my career, I have been committed to providing training and mentorship for students and junior faculty in the US and in many countries in Africa including Tanzania, Rwanda, and Zimbabwe. I developed and co-led a course focused on building skills to produce scholarly mentored projects for students at Harvard Medical School, serve as a mentor for the Northwestern AOSC program and am co-PI for a newly funded D43 project in Tanzania to build capacity for patient centered outcome research. and have led multiple workshops to build capacity for measurement and interventions to improve quality of care, both technical and patient’s experience. Current projects include exploring barriers to pre-exposure prophylaxis for HIV for women in Chicago, primary health care improvement in low and middle income setting, strengthening quality measurement focusing on people-centered care and evaluation of quality improvement collaboratives in Africa.
My academic work has focused on understanding and improving disparities in quality and outcomes of health care in the united Stated and globally using implementation research. This work has ranged from understanding quality of care for women with HIV in the US to neonatal mortality reduction in Rwanda and improving maternal care in India. As an implementation and improvement scientist, I have also worked to develop novel approaches to using mixed methods to better understand these gaps and leverage the use of routine health information and more efficient measurement strategies. I am also working to increase the effectiveness of research to identify and understand disparities in care and outcomes, increasing data use and policy change o drive evidence-based decision making working with organizations including the Doris Duke Charitable foundation, the Bill and Melinda Gates Foundation and the World Health Organization.
Training Experience
1986 | Internship, Beth Israel Deaconess Medical Center, Boston |
1988 | Fellowship, Beth Israel Deaconess Medical Center, Boston |
1988 | Residency, Beth Israel Deaconess Medical Center, Boston |
1989 | Fellowship, Beth Israel Deaconess Medical Center, Boston |
1991 | Postdoctoral Fellowship, Beth Israel Deaconess Medical Center |
1992 | Postdoctoral Fellowship, Brigham and Women's Hospital and Beth Israel Hospital, Harvard |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MPH, Public Health, Harvard School of Public Health
… → 1992
MD, Medicine, Columbia College of Physicians and Surgeons
… → 1985
Research interests keywords
- AIDS
- Global Health
- Healthcare Quality
- Mixed Methods
- Program Evaluation
- Quality Improvement
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Evaluation of PrEP implementation strategies for the general population in Botswana
Hirschhorn, L. R. (PD/PI), Hirschhorn, L. R. (PD/PI), Van Pelt, A. E. (Co-Investigator) & Van Pelt, A. E. (Co-Investigator)
University of Botswana, National Institute of Mental Health
8/5/24 → 5/31/29
Project: Research project
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Examining the role of implementation strategies in sustaining evidence-based interventions in home visiting
Tandon, D. (PD/PI), Berry, A. B. (Co-Investigator) & Hirschhorn, L. R. (Co-Investigator)
National Institute of Mental Health
7/1/24 → 6/30/26
Project: Research project
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NEST 360 Phase 2 Advance Account 3
Hirschhorn, L. R. (Other) & Hirschhorn, L. R. (Other)
Rice University, Children's Investment Fund Foundation (UK)
1/1/24 → 12/31/28
Project: Research project
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NEST 360 Phase 2
Hirschhorn, L. R. (Other) & Hirschhorn, L. R. (Other)
Rice University, Bill & Melinda Gates Foundation
1/1/24 → 12/31/28
Project: Research project
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FOREST (Fostering Optimal Regulation of Emotion for prevention of Secondary Trauma): Implementation and evaluation of a burnout prevention program for staff in gun violence prevention programs
Moskowitz, J. T. (PD/PI), Addington, E. L. (Co-Investigator), Burnett-Zeigler, I. E. (Co-Investigator), Hirschhorn, L. R. (Co-Investigator), Papachristos, A. V. (Co-Investigator) & Phillips II, G. (Co-Investigator)
National Center for Complementary and Integrative Health
9/17/23 → 8/31/26
Project: Research project
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Blood biomarkers of trans-fatty acid intake among Nigerian adults in the Federal Capital Territory: a cross-sectional study
Marklund, M., Billyrose, S., Orji, I. A., Ikechukwu-Orji, M. U., Okoro, C., Obagha, C., Iyer, G., Jamro, E. L., Ojo, A., Harris, W. S., Wu, J. H., Hirschhorn, L. R., Van Horn, L., Huffman, M. D. & Ojji, D. B., Jan 2025, In: American Journal of Clinical Nutrition. 121, 1, p. 125-133 9 p.Research output: Contribution to journal › Article › peer-review
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Conceptualizing patient-level adverse effects in implementation trials
Goss, C. W., Filiatreau, L. M., Hirschhorn, L. R., Huffman, M. D., Mody, A., Powell, B. J., Tetteh, E., Geng, E. H. & Mosepele, M., Feb 2025, In: Annals of Epidemiology. 102, p. 55-61 7 p.Research output: Contribution to journal › Article › peer-review
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A hybrid type II effectiveness-implementation trial of a positive emotion regulation intervention among people living with HIV engaged in Ryan White Medical Case Management: protocol and design for the ORCHID study
Xavier Hall, C. D., Ethier, K., Cummings, P., Freeman, A., Bovbjerg, K., Bannon, J., Dakin, A., Abujado, F., Bouacha, N., Derricotte, D., Patterson, L., Hirschhorn, L. R., Bouris, A. & Moskowitz, J. T., Dec 2024, In: Trials. 25, 1, 631.Research output: Contribution to journal › Article › peer-review
Open Access -
A mixed methods approach identifying facilitators and barriers to guide adaptations to InterCARE strategies: an integrated HIV and hypertension care model in Botswana
Gala, P., Ponatshego, P., Bogart, L. M., Youssouf, N., Ramotsababa, M., Van Pelt, A. E., Moshomo, T., Dintwa, E., Seipone, K., Ilias, M., Tonwe, V., Gaolathe, T., Hirschhorn, L. R. & Mosepele, M., Dec 2024, In: Implementation Science Communications. 5, 1, 67.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Barriers and facilitators to the delivery of age-friendly health services in Primary Health Care centres in southwest, Nigeria: A qualitative study
Ogunyemi, A. O., Balogun, M. R., Ojo, A. E., Welch, S. B., Onasanya, O. O., Yesufu, V. O., Omotayo, A. T. & Hirschhorn, L. R., Mar 2024, In: PloS one. 19, 3 MARCH, e0288574.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Datasets
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Data-driven quality improvement in low-and middle-income country health systems: lessons from seven years of implementation experience across Mozambique, Rwanda, and Zambia
Wagenaar, B. H. (Creator), Hirschhorn, L. R. (Creator), Henley, C. (Creator), Gremu, A. (Creator), Sindano, N. (Contributor) & Chilengi, R. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3960531.v1, https://figshare.com/collections/Data-driven_quality_improvement_in_low-and_middle-income_country_health_systems_lessons_from_seven_years_of_implementation_experience_across_Mozambique_Rwanda_and_Zambia/3960531/1
Dataset
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Assessing the Integrated Community-Based Health Systems Strengthening initiative in northern Togo: a pragmatic effectiveness-implementation study protocol
Lauria, M. E. (Creator), Fiori, K. P. (Creator), Jones, H. E. (Creator), Gbeleou, S. (Contributor), Kenkou, K. (Contributor), Agoro, S. (Contributor), Agbèrè, A. D. (Contributor), Lue, K. D. (Creator) & Hirschhorn, L. R. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4701698, https://springernature.figshare.com/collections/Assessing_the_Integrated_Community-Based_Health_Systems_Strengthening_initiative_in_northern_Togo_a_pragmatic_effectiveness-implementation_study_protocol/4701698
Dataset
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Stakeholder perspectives to inform adaptation of a hypertension treatment program in primary healthcare centers in the Federal Capital Territory, Nigeria: a qualitative study
Okoli, R. C. B. (Creator), Shedul, G. (Creator), Hirschhorn, L. R. (Creator), Orji, I. A. (Creator), Ojo, T. M. (Creator), Egenti, N. (Creator), Omitiran, K. (Creator), Akor, B. (Creator), Baldridge, A. S. (Creator), Huffman, M. D. (Creator), Ojji, D. (Creator) & Kandula, N. R. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5594839, https://springernature.figshare.com/collections/Stakeholder_perspectives_to_inform_adaptation_of_a_hypertension_treatment_program_in_primary_healthcare_centers_in_the_Federal_Capital_Territory_Nigeria_a_qualitative_study/5594839
Dataset
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Adapting and usability testing of the Kansas city cardiomyopathy questionnaire (KCCQ) in a heart failure clinic in Tanzania: the Swahili KCCQ
Chillo, P. (Creator), Mlay, J. (Creator), Akanyirige, P. W. (Creator), Majani, N. (Creator), Janabi, M. (Creator), Kaaya, S. (Creator), Hawkins, C. (Creator) & Hirschhorn, L. R. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.c.6634622, https://springernature.figshare.com/collections/Adapting_and_usability_testing_of_the_Kansas_city_cardiomyopathy_questionnaire_KCCQ_in_a_heart_failure_clinic_in_Tanzania_the_Swahili_KCCQ/6634622
Dataset
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Does distance from a clinic and poverty impact visit adherence for noncommunicable diseases? A retrospective cohort study using electronic medical records in rural Haiti
Yan, L. D. (Creator), Pierre-Louis, D. (Contributor), Isaac, B. D. (Creator), Jean-Baptiste, W. (Contributor), Vertilus, S. (Creator), Fenelon, D. (Creator), Hirschhorn, L. R. (Creator), Hibberd, P. L. (Creator), Benjamin, E. J. (Contributor), Bukhman, G. (Creator) & Kwan, G. F. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.c.5175403, https://springernature.figshare.com/collections/Does_distance_from_a_clinic_and_poverty_impact_visit_adherence_for_noncommunicable_diseases_A_retrospective_cohort_study_using_electronic_medical_records_in_rural_Haiti/5175403
Dataset